White Core Research Articles

Evolution mechanism of Ti(C,N)-based cermet microstructure under microwave sintering

Experimental studies of microwave-sintered cermets were carried out at different sintering temperatures and holding times to investigate their microstructure evolution mechanism. Results of the study show that: (1) As sintering temperature increases, main microstructure evolution mechanisms of cermets are as follows: metal-phase melting, hard-phase skeleton filling of large pores in hard-phase skeletons, secondary rearrangement of the liquid phase (the liquid phase gradually fills the space between grains), and cooling down (precipitation–crystallization–reattachment); (2) As holding time increases, main microstructure evolution mechanisms of cermets are as follows: complete filling of large pores in the hard-phase skeleton, secondary rearrangement of the liquid phase, intense dissolution precipitation enhancing the formation of core-rim phase, and secondary homogeneous arrangement of the liquid phase. The special electromagnetic effects of microwave-sintered cermets and their influence on the sintering process were analyzed. It was found that both tip-discharge effect and hot-spot effect occurring during the microwave sintering process are conducive to the sintering process. The formation process of core-rim phase of cermets was also studied. Results show that: (1) Cermets form black core–white rim–grey rim structure via dissolution–precipitation and precipitation–crystallization phenomena; (2) Cermets form white core–grey rim structure through agglomeration of small particles, dissolution–precipitation, and precipitation–crystallization phenomena.

Universal Diffusion in Coulomb Crystals.

Diffusion coefficients for crystallized Coulomb plasmas are essential microphysics input for modeling white dwarf cores and neutron star crusts but are poorly understood. In this work we present a model for diffusion in Coulomb crystals. We show that melting and diffusion follow the same universal scaling such that diffusion is independent of screening. Our simulations show, contrary to prevailing wisdom, that the formation of vacancies is not suppressed by the large pressure. Rather, vacancy formation and hole diffusion is the dominant mode of self-diffusion in Coulomb crystals.

Heavy dark matter in white dwarfs: multiple-scattering capture and thermalization

We present an improved treatment for the scattering of heavy dark matter from the ion constituents of a white dwarf. In the heavy dark matter regime, multiple collisions are required for the dark matter to become gravitationally captured. Our treatment incorporates all relevant physical effects including the dark matter trajectories, nuclear form factors, and radial profiles for the white dwarf escape velocity and target number densities. Our capture rates differ by orders of magnitude from previous estimates, which have typically used approximations developed for dark matter scattering in the Earth.We also compute the time for the dark matter to thermalize in the center of the white dwarf, including in-medium effects such as phonon emission and absorption from the ionic lattice in the case where the star has a crystallized core. We find much shorter thermalization timescales than previously estimated, especially if the white dwarf core has crystallized.We illustrate the importance of our improved approach by determining the cross section required for accumulated asymmetric dark matter to self-gravitate.

Supernovae and superbursts triggered by dark matter clumps

Cosmologies in which dark matter clumps strongly on small scales are unfavorable to terrestrial detectors that are as yet unexposed to the clumps. I show that subhectometer clumps could trigger thermonuclear runaways by scattering on nuclei in white dwarf cores (carbon and oxygen) and neutron star oceans (carbon), setting off type-Ia-like supernovae and x-ray superbursts, respectively. I consider two scenarios: “dark clusters” that are essentially microhalos and “long-range dark nuggets,” essentially macroscopic composites, with long-range Yukawa baryonic interactions that source the energy for igniting explosions. I constrain dark clusters, weighing between the Planck mass and asteroid masses, and long-range dark nuggets over a wider mass range spanning 40 orders of magnitude. These limits greatly complement searches proposed by myself and co-workers [] for scattering interactions of dark clumps in neutron stars, cosmic rays, and prehistoric minerals. Published by the American Physical Society 2024

Laughing from the Outside‐In: Considering ‘What's Up Africa’ as an(other) humorous humanitarian digilantism

AbstractThis article examines the intersection of humour and humanitarianism in engaging Northern audiences with global Southern poverty issues. It analyses witty social media campaigns that critique humanitarian practices and Africa’s representation, notably What’s Up Africa (WUA) on YouTube, Radi‐Aid on YouTube, Humanitarians of Tinder on Tumblr and Barbie Savior on Instagram. Using ‘contraflow’, it shows how humour and positionality shape reception. WUA’s Black African‐centric comedy, particualrly, highlights the often‐underexplored role of race in development discourse, challenging the White institutional core of humanitarianism. These insights reveal power dynamics and invite further academic inquiry into the transformative potential of comedic humanitarian critique.

Effectiveness of endoscopic ultrasound-guided tissue acquisition with stereomicroscopic on-site evaluation for preoperative diagnosis of resectable or borderline resectable pancreatic cancer: a prospective study.

To validate endoscopic ultrasound-guided tissue acquisition (EUS-TA) used in conjunction with stereomicroscopic on-site evaluation (SOSE) as a preoperative diagnostic tool for resectable pancreatic cancer (R-PC) and borderline resectable PC (BR-PC). Seventy-eight consecutive patients who underwent EUS-TA for suspected R-PC or BR-PC were enrolled. The primary endpoint was the sensitivity of EUS-TA together with SOSE based on the stereomicroscopically visible white core (SVWC) cutoff value. One or two sites were punctured by using a 22-gauge biopsy needle for EUS-TA, based on the SOSE findings. We collected 99 specimens from 56 and 22 patients with R-PC and BR-PC, respectively. Based on the SOSE results, we performed 57 procedures with one puncture. The SVWC cutoff values were met in 73.7% and 73.1% of all specimens and in those obtained during the first puncture, respectively. The final diagnoses were malignant and benign tumors in 76 and two patients, respectively. The overall sensitivity, specificity, and accuracy of EUS-TA for the 78 lesions were 90.8%, 100%, and 91.0%, respectively. The sensitivity for malignant diagnosis based on the SVWC cutoff value were 89.5% and 90.4% for the first puncture and all specimens, respectively. The sensitivity of EUS-TA in conjunction with SOSE for malignancy diagnosis in patients with suspected R-PC or BR-PC was 90.4%.

Endoscopic Ultrasound-Guided Tissue Acquisition Using Fork-Tip Needle for Subepithelial Lesions: A Single-Center Validation Study.

The cutoff value for stereomicroscopic on-site evaluation (SOSE) in endoscopic ultrasound-guided tissue acquisition (EUS-TA) has high diagnostic sensitivity when a Franseen needle is employed for upper gastrointestinal subepithelial lesions (SELs) (stereomicroscopically visible white core [SVWC] ≥ 4mm). We aimed to determine whether high diagnostic sensitivity could be obtained when EUS-TA was performed using a Fork-tip needle. Twenty-one patients were prospectively registered. Patients underwent EUS-TA using a Fork-tip needle for upper gastrointestinal SELs at Kitasato University Hospital between January and November 2022. Punctures were made twice using the needle, and SOSE was conducted for each specimen. Blood and physical examination were performed to assess adverse events. Pathological diagnosis was made using hematoxylin and eosin-stained sections and immunohistochemical staining. Statistical comparisons were completed using Fisher's exact tests. The diagnostic rate of EUS-TA was 100% (21/21 cases). The final diagnosis was gastrointestinal stromal tumor in 17 (81.0%) and leiomyoma in 4 (19.0%) patients. SOSE was conducted on all 42 punctures, and the tissue sampling rate was 100% (42/42 punctures). Specimens with SVWC ≥ 4mm were collected in 97.6% punctures (41/42 punctures) and the diagnostic sensitivity for these specimens was 100% (41/41 punctures), which is significantly higher (p < 0.0238) compared to the absence of cutoff value (diagnostic sensitivity of 0%). No EUS-TA-related adverse events occurred. EUS-TA combined with SOSE for upper gastrointestinal SEL using a fork-tip needle had a high diagnostic rate, and the cutoff value of SVWC ≥ 4mm had high diagnostic sensitivity.

Elastic and breaking properties of epitaxial face‐centered crystals in neutron star crusts and white dwarf cores

AbstractCrystallization of dense matter in neutron star crusts and white dwarf cores may be similar to epitaxial crystal growth in terrestrial laboratories. However, in stellar crystals, the spacing between horizontal planes has to gradually increase with the outward movement of the crystallization front, tracing decrease of the electron density. This process produces Coulomb crystals with stretched rather than cubic elementary cells. We extend the analysis of the elastic and breaking properties of such crystals to the face‐centered (fc) lattice. Shear deformations orthogonal to the stretch direction have been studied for 22 crystallographic shear planes. A common property for all these planes is the reduction and eventual nulling of the breaking shear strain with deviation from the unstretched configuration. The effective shear moduli for deformations orthogonal to the stretch direction have been calculated. It is possible that the epitaxial crystallization in compact stars results in a formation of large‐scale crystallites or, at least, in growth of the whole crystallization front perpendicular to particular crystallographic planes. For fc structure growth orthogonal to the planes, we expect that, at any density, () of crystallite height is occupied by layers one (two) orders of magnitude weaker than the bulk of the crystallite. This may be important for realistic modeling of crustquakes on neutron stars.

The Impact of Breathing Pulses during Core Helium Burning on the Core Chemical Structure and Pulsations of Hydrogen-rich Atmosphere White Dwarfs

Breathing pulses are mixing episodes that could develop during the core helium-burning phase of low- and intermediate-mass stars. The occurrence of breathing pulses is expected to bear consequences on the formation and evolution of white dwarfs, particularly on the core chemical structure, which can be probed by asteroseismology. We aim to explore the consequences of breathing pulses on the chemical profiles and pulsational properties of variable white dwarf stars with hydrogen-rich envelopes, known as ZZ Ceti stars. We compute stellar models with masses of 1.0M ⊙ and 2.5M ⊙ in the zero-age main sequence and evolve them through the core helium-burning phase to the thermal pulses on the asymptotic giant branch, and finally to advanced stages of white dwarf cooling. We compare the chemical structure of the core of white dwarfs whose progenitors have experienced breathing pulses during the core helium-burning phase with the case in which breathing pulses have not occurred. We find that when breathing pulses occur, the white dwarf cores are larger and the central abundances of oxygen are higher than for the case in which the breathing pulses are suppressed, in line with previous studies. However, the occurrence of breathing pulses is not sufficient to explain the large cores and the excessive oxygen abundances that characterize recently derived asteroseismological models of pulsating white dwarfs. We find absolute differences of up to ∼30 s when we compare pulsation periods of white dwarfs coming from progenitors that have experienced breathing pulses with the case in which the progenitors have not suffered breathing pulses.

Rice grain structural characteristics of sake rice cultivar Hakutsurunishiki for daiginjo-shu brewing.

Hakutsurunishiki is a sake rice cultivar bred using Yamadabo (seed parent) and Wataribune 2 (pollen parent), equivalent to a Yamadanishiki sibling. This study evaluated the structural characteristics of the Hakutsurunishiki rice grain that contribute to the brewing characteristics of daiginjo-shu, via a comparison with Yamadanishiki. Hakutsurunishiki brown rice was a little heavy and had a large white core. Observing a cross-section of white rice after soaking revealed that the rice grain structure of Hakutsurunishiki was different from that of Yamadanishiki. Hakutsurunishiki white rice showed fewer voids than Yamadanishiki, promoting a slower water absorption rate. Glucose distribution in rice koji obtained by mass spectrometry imaging showed that Hakutsurunishiki rice koji, like Yamadanishiki, is tsuki-haze type, suggesting that its grain structure is suitable for making rice koji for daiginjo-shu. With these observations, we were able to clarify the structural characteristics of Hakutsurunishiki rice grain.

Efficacy of endoscopic ultrasound-guided tissue acquisition using stereo-microscopic on-site evaluation for possible comprehensive genome profile in patients with advanced pancreatic cancer.

Stereomicroscopic on-site evaluation (SOSE) is a rapid evaluation method for endoscopic ultrasound-guided tissue acquisition (EUS-TA) with a high diagnostic sensitivity when the stereomicroscopically visible white core (SVWC) cut-off value (≥11mm) is met. We prospectively examined the association between SVWCs and the adequacy of tissue specimens, assuming subsequent comprehensive genome profiling (CGP). This study included 66 consecutive patients with suspected unresectable pancreatic cancer who underwent EUS-TA. The primary endpoint was the frequency of combined samples with ≥20% tumor cell content that met over twice the SVWC (T-SVWC) cut-off value, achieved through multiple punctures. The secondary endpoints were the number of punctures, the percentage of SVWC cut-off values, adverse events, the positive diagnosis rate, and the tissue section area. The median number of EUS-TA punctures for suspected unresectable pancreatic cancer was 3 (range, 3-4); SVWC and T-SVWC cut-off values were obtained in 171/206 specimens and 65/66 patients, respectively. There were no EUS-TA-related adverse events. The positive diagnosis rate of EUS-TA was 95.5%. Among the 63 patients meeting the T-SVWC cut-off value in pathological diagnoses, the median tumor cell content was 40% (range, 5-80%), with 57 patients having tumor cell content ≥20%. The median tissue section area was 15 (range, 3-40) mm2. When performing EUS-TA for unresectable pancreatic cancer with the intention of subsequent CGP, obtaining a high tumor cell content (≥20%) by assessing the T-SVWC cut-off value via SOSE may serve as a novel indicator for on-site estimation of CGP suitability for EUS-TA specimens.

Liquid-phase epitaxy of neutron star crusts and white dwarf cores

ABSTRACT Near-equilibrium bottom-up crystallization of fully ionized neutron star crusts or white dwarf cores is considered. We argue that this process is similar to liquid-phase epitaxial (i.e. preserving order of previous layers) crystal growth or crystal pulling from melt in Earth laboratories whereby lateral positions of newly crystallizing ions are anchored by already solidified layers. Their vertical positions are set by charge neutrality. Consequently, interplane spacing of a growing crystal either gradually increases, tracing ne decrease, as the crystallization front moves away from the stellar centre, or decreases, tracing decrease of 〈Z〉, when the crystallization front crosses a boundary between layers of different compositions. This results in the formation of stretched Coulomb crystals, in contrast to the standard assumption of cubic crystal formation, which is based on energetics arguments but does not take into account growth kinetics. Overstretched crystals break, which limits the vertical sizes of growing crystallites. We study breaking shear strain and effective shear modulus of stretched matter and discuss possibility of macrocrystallite formation. The latter has interesting astrophysical implications, for instance, appearance of weak crustal layers, whose strength may increase by a few orders of magnitude upon breaking and refreezing at a late-time event. We also analyse interaction of adjacent Coulomb crystals, having different ion compositions, and estimate the strength of such interfaces.

Tissue processing of endoscopic ultrasound-guided fine-needle aspiration specimens from solid pancreatic lesions.

Now that tissue cores can be obtained using fine-needle biopsy (FNB) needles, the ways tissues are handled for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) are changing. Direct smear, touch smear of core tissues, and centrifugation have been used for cytological examinations, and liquid-based cytology (LBC), which allows immunostaining and genetic tests that use residual samples, is emerging as an alternative. We emphasize that liquid cytology (Cytospin™ cytology and LBC) is still important, because it enables the diagnosis of pancreatic ductal adenocarcinoma (PDAC) when cancerous cells are scarce in specimens. Cell blocks are being replaced by core tissues obtained via FNB needles. Recent reports indicate that rapid on-site evaluation (ROSE) is not necessary when FNB needles are used, and macroscopic on-site evaluation is used to evaluate specimen adequacy. Macroscopic findings of specimens are helpful in the diagnostic workup and for clarifying specimen-handling methods. In addition to the red strings and white cores observed in PDAC, mixed red and white strings, gray tissues, and gelatinous tissues are observed. Gray (necrotic) tissues and gelatinous (mucus) tissues are more suitable than histology for cell block or cytological processing. Tumor cells in neuroendocrine tumors (NETs) are numerous in red strings but cannot be observed macroscopically. ROSE might thus be necessary for lesions that may be NETs. Core tissues can be used for genetic tests, such as those used for KRAS mutations and comprehensive genomic profiling. Cytological materials, including slides and LBC specimens, can also be genetic test materials.

Glacial secrets uncovered: Revealing the modes of survival of metabolically active microbial communities entrapped in polar glacial ice

Glacial secrets uncovered: Revealing the modes of survival of metabolically active microbial communities entrapped in polar glacial ice

Macroscopic qualitative evaluation of solid pancreatic lesion specimens from endoscopic ultrasound-guided fine needle aspiration/biopsies

ObjectivesTo pathologically clarify the macroscopic features of endoscopic ultrasound-guided fine needle aspiration/biopsy (EUS-FNA/B) specimens in representative pancreatic diseases and establish tissue-handling standards based on the macroscopic findings. MethodsWe gathered EUS-FNA/B specimens of cases at our institution with the final diagnoses of pancreatic ductal adenocarcinoma (PDAC, n = 172), neuroendocrine tumor (NET, n = 19), and chronic inflammatory lesion (CIL, n = 24) including autoimmune pancreatitis. We classified the specimens' macroscopic features in five categories (red strings, mixed-red-and-white strings, white cores, gray tissues, gelatinous tissues) and compared the specimens' features on cytological and histological slides. ResultsAll five macroscopic categories were observed in variable combinations in the PDACs; red strings and white cores predominated in the NETs and CILs. White cores represented neoplastic (PDAC, NET) or lesion (CIL) tissues. Mixed-red-and-white strings were unique to PDACs and contained cancerous cells. Neoplastic cells were numerous in red strings in NETs but not the other groups. Gray and gelatinous tissues represented necrosis and mucin, respectively, and the former were almost exclusively observed in PDACs. Red strings, mixed-red-and-white strings, and white cores were suitable for histological examination, whereas gray and gelatinous tissues were suitable for cytological examination. The white cores, mixed-red-and-white strings, and gelatinous tissues may be composed of non-neoplastic tissues such as contaminated gastrointestinal epithelium. In seven PDACs, although white cores were obtained, a histological diagnosis was not established. ConclusionsMacroscopic evaluations of EUS-FNA/B can enable the identification of specimen components and a possible diagnosis. They also contribute to the selection of the optimal tissue-handling methods.

A theoretical study of heavy nucleus-acoustic waves in white dwarf core environments

A theoretical study of heavy nucleus-acoustic waves in white dwarf core environments

In vivo Evaluation of Shade Replication of Different Generations of Zirconia to Natural Teeth Using Digital Color Determinations.

The color difference between the final shade of restorations milled from different zirconia blocks, and the control teeth in the esthetic zone is yet uncertain. For eight patients who required a singular maxillary central incisor restoration, twenty-four crowns made of zirconia were created. These were grouped into three categories based on the shade and nature of zirconia (Zr) utilized (white core, colored core, and monolithic high-translucency (ht) Zr crowns). The difference in color (ΔE) between the three zirconia crowns and the neighboring teeth was calculated by the use of Easyshade spectrophotometer. Two shades of resin luting cement were used. The measured ΔE values were evaluated based on a clinically acceptable color difference of 1.6ΔE, which is not visible to the human eye. Among the three groups, no differences of statistical significance were observed in terms of ΔE with different Zr types and resin cement color. Within the limits of this study, the usage of different shades of zirconia blanks and resin cements did not display a statistically significant effect on the final color of the crown. Changing the shade of resin cements does not appear to add value to the final shade of crown. In addition, the generation of zirconia does not influence the shade of the crown. Crowns made of zirconia can be cemented with opaque or transparent cement with no effect on the final color.

The (im)possibility of complaint: on efforts of inverting and (en)countering the university

ABSTRACT Over the past decades, research has documented how endemic racism, sexism, and ableism are in academia. Universities have complaint procedures to address these issues. Much research focuses on individual experiences of making a complaint and the institutional uptake of complaints and demonstrates how such ‘isms’ are located in the individual rather than in the institution. This paper instead scrutinizes how complaint procedures mask and reproduce the structures with which complaints are concerned resulting in the complaints’ limited transformative abilities. I demonstrate how complaint procedures only allow for treating complaints as isolated, singular and unusual events that require temporary solutions, which ensures that complaints and complaint work are peripheralized while the white patriarchal ableist core of universities remains intact. Complaints as efforts of inverting the white patriarchal university are too limited as they are quickly reverted. Hence, what is needed is more than a mere procedure but a total inversion of the institution to make difference fit which requires work that goes in and beyond one’s institution.

Integrated genome-wide differentiation and association analyses identify causal genes underlying breeding-selected grain quality traits in japonica rice

Improving grain quality is a primary objective in contemporary rice breeding. Japanese modern rice breeding has developed two different types of rice, eating and sake-brewing rice, with different grain characteristics, indicating the selection of variant gene alleles during the breeding process. Given the critical importance of promptly and efficiently identifying genes selected in past breeding for future molecular breeding, we conducted genome scans for divergence, genome-wide association studies, and map-based cloning. Consequently, we successfully identified two genes, OsMnS and OsWOX9D, both contributing to rice grain traits. OsMnS encodes a mannan synthase that increases the white core frequency in the endosperm, a desirable trait for sake brewing but decreases the grain appearance quality. OsWOX9D encodes a grass-specific homeobox-containing transcription factor, which enhances grain width for better sake brewing. Furthermore, haplotype analysis revealed that their defective alleles were selected in East Asia, but not Europe, during modern improvement. In addition, our analyses indicate that a reduction in grain mannan content during African rice domestication may also be caused a defective OsMnS allele due to breeding selection. This study not only reveals the delicate balance between grain appearance quality and nutrition in rice but also provides a new strategy for isolating causal genes underlying complex traits, based on the concept of “breeding-assisted genomics” in plants.

White Rabbit Expansion Board: Design, Architecture, and Signal Integrity Simulations

The White Rabbit protocol allows synchronization and communication via an optical link in an integrated, modular, and scalable manner. It provides a solution to those applications that have very demanding requirements in terms of synchronization. Field-programmable gate arrays are used to implement the protocol; additionally, special hardware is needed to provide the necessary clock signals used by the dual-mixer time difference for precise phase measurement. In the present work, an expansion board that allows for White Rabbit functionality is presented. The expansion board contains the oscillators required by the White Rabbit protocol, one running at 125 MHz and another at 124.922 MHZ. The architecture of this board includes two oscillator systems for tests and comparison. One is based on VCOs and another on crystal oscillators running at the desired frequencies. In addition, it incorporates a temperature sensor, from where the medium access control address is extracted, an electrically erasable programmable read-only memory, a pulse-per-second output, and a USB UART to access the White Rabbit IP core at the field-programmable gate array. Finally, to ensure the quality of the layout design and guarantee the level of synchronization desired, the results of the power and signal integrity simulations are also presented.