Here, we point out that interactions with time delay can be described at the quantum level using a multi-time wave function , i.e. a wave function depending on one spacetime variable per particle. In particular, such a wave function makes it possible to implement direct interaction along light cones (not mediated by fields), as in the Wheeler–Feynman formulation of electrodynamics. Our results are as follows. (1) We derive a covariant two-particle integral equation and discuss it in detail. (2) It is shown how this integral equation (or equivalently, a system of two integro-differential equations) can be understood as defining the time evolution of ψ in a consistent way. (3) We demonstrate that the equation has strong analogies with Wheeler–Feynman electrodynamics and therefore suggests a possible new quantization of that theory. (4) We propose two natural ways how the two-particle equation can be extended to N particles. It is shown that exactly one of them leads to the usual Schrödinger equation with Coulomb-type pair potentials if time delay effects are neglected.