Combination Of Western Medicine Research Articles

Research Progress on the Combination of Traditional Chinese Medicine and Western Medicine for the Treatment of Ischemic Cardiomyopathy

Ischemic cardiomyopathy (ICM) refers to contractile left ventricular dysfunction in the case of severe coronary stenosis, which is the most common cause of heart failure. In recent years, the incidence of ICM has shown a significant upward trend, and the quality of life and life safety of patients have been seriously affected. At present, the treatment of ICM mainly focuses on dilating blood vessels, diuresis, improving myocardial metabolism and enhancing myocardial function. Research shows that traditional Chinese medicine has unique advantages in improving the prognosis and quality of life of ICM patients. There are a variety of treatment methods, including decoction, injections, proprietary Chinese medicine, etc. This article summarizes the research progress of ICM's traditional Chinese medicine, western medicine and integrated traditional Chinese and western medicine, with a view to providing reference for clinical treatment.

Research Progress of Integrated Traditional Chinese and Western Medicine in the Treatment of Early Diabetic Nephropathy

Diabetic nephropathy (DN) is a specific damage of diabetes, early DN can be manifested as microproteinuria, the symptoms are insidious, not easy to be detected, it will cause irreversible damage to the kidneys in a short period of time, and it can develop into kidney failure with the gradual progression of the disease, which seriously threatens the health of patients. Therefore, early intervention and effective treatment are crucial to reverse kidney damage and delay the progression of the disease. This article analyzes the literature on the treatment of DN in recent years, and clarifies that the combination of traditional Chinese and Western medicine has an ideal effect in the treatment of early DN, in order to provide reference for the clinical treatment of DN.

A Case of Peritoneal Dialysis-associated Encapsulated Peritoneal Sclerosis Treated with a Combination of Chinese and Western Medicine

A Case of Peritoneal Dialysis-associated Encapsulated Peritoneal Sclerosis Treated with a Combination of Chinese and Western Medicine

Clinical efficacy and pharmacological mechanism analysis of Xubi Capsule in the treatment of patients with liver and kidney deficiency osteoarthritis.

To explore the clinical efficacy and pharmacological mechanism analysis of Xubi capsule in the treatment of patients with liver and kidney deficiency osteoarthritis (OA). In this single-center retrospective study, 120 patients with liver and kidney deficiency OA admitted to the Hangzhou Fuyang Hospital of Traditional Chinese Medicine from January 2020 to May 2022 were included, and patients were divided into the intervention group (n = 60) and the control group (n = 60) according to their treatment. The control group was treated with Ibuprofen, while the intervention group was treated with Xubi capsule combined with Ibuprofen. According to the network pharmacology method, the mechanism of the Xubi capsule in the treatment of patients with liver and kidney deficiency OA was analyzed. After the treatment, the total effective rate in the intervention group was 93.33%, which was significantly higher than that in the control group (P < .001). After treatment, compared with the control group, the degree of joint swelling and tenderness in the intervention group were lighter, the muscle strength was better, the level of erythrocyte sedimentation rate was lower, and the pain visual score was lower (P < .05), while the C-reactive protein level was significantly lower (P < .001). The effective chemical composition of Xubi capsules is 176, with quercetin and palmitoleic acid being the most associated with diseases. There are 209 intersection targets between drugs and diseases. A total of 119 gene ontology cellular components were significantly enriched. The combination of traditional Chinese medicine and Western medicine adopted in this study can effectively treat patients with liver and kidney deficiency OA and relieve the joint pain of patients. In a multicomponent and multitarget approach, the Xubi capsule breaks through the limitations of traditional nonsteroidal anti-inflammatory drugs and has good clinical application value.

Research Progress in Integrated Chinese and Western Medicine Health Management for School-Age Children with Asthma

Objective: The purpose of this study is to investigate the application of Chinese and Western medicine in the health management of school-age children with asthma and its research progress, with a view to providing a more comprehensive and effective management strategy for the clinic. Methods: Using the method of literature review, this study systematically searched and analyzed the relevant studies on the combination of Chinese and Western medicine in the health management of school-aged children with asthma in recent years, focusing on Chinese medicine treatment, Western medicine treatment, and the combined health management of Chinese and Western medicine. Results: Chinese medicine treatment, Western medicine treatment, and the health management mode of combining Chinese and Western medicine showed unique advantages in school-age asthmatic children. Through the comprehensive use of Chinese medicine’s diagnosis and treatment, Chinese medicine conditioning, Chinese medicine characteristic therapy, and Western medicine’s modern medical methods, it not only effectively relieved asthma symptoms but also significantly improved the quality of life of the children. At the same time, this management mode also focuses on the psychological guidance and family care of the children, forming an all-round and multi-level health management system. Conclusion: The health management strategy of combining Chinese and Western medicine has a broad application prospect in school-age asthmatic children, and its specific interventions and mechanisms of action should be further studied to provide more scientific and systematic guidance for clinical practice.

Efficacy and safety of combined Chinese and western medicine in the treatment of metabolic syndrome: A network meta-analysis of randomized controlled trials

ObjectivesTo comprehensively analyze the randomized controlled clinical trials of integrated traditional Chinese medicine (TCM) and western medicine in the treatment of metabolic syndrome (MetS), and to explore the clinical efficacy and safety of different TCM combined with western medicine for MetS. The purpose of this study is to provide specific suggestions for clinical guidance in the treatment of MetS. MethodsA comprehensive literature review was conducted across several databases, including China Knowledge Network, Wanfang Data, VIP Information, China Biomedical Literature Service System, Embase, PubMed, and Web of Science, up to October 2023. The scope of this review was confined to RCTs focusing on the treatment of metabolic syndrome through an integrated approach of TCM and Western medicine. The primary efficacy endpoints analyzed were clinical efficacy, fasting blood glucose (FBG), triglyceride (TG), and high-density lipoprotein (HDL). Data synthesis and analysis were performed using Stata 16 and RevMan 5.4 for both traditional and network meta-analyses. ResultsThe findings from both traditional and network meta-analyses reveal that the combination of JiangZhiHuoXue pills (JZHX) + Conventional Western Medicine (CWM) significantly reduces FBG levels. Similarly, the AnShenNingXin capsules (ASNX) + CWM combination markedly lowers TG levels, while the FuFangQiMa capsules (FFQM) + CWM combination shows enhanced efficacy in elevating HDL levels. Notably, the combination of KangNing capsules (KNJN) + CWM demonstrates a more pronounced clinical effect compared to CWM/placebo alone. ConclusionsThe study concludes that the synergistic combination of TCM and Western medicine exhibits superior therapeutic benefits in treating MetS compared to CWM/Placebo treatments alone. The combinations of JZHX, AXNX, FFQM, and KNJN with CWM emerge as potentially effective treatments.

Liver cirrhosis: current status and treatment options using western or traditional Chinese medicine.

Liver cirrhosis arises from liver fibrosis and necroinflammation caused by various mechanisms of hepatic injury. It is a prevalent condition in clinical practice characterized by hepatocellular dysfunction, portal hypertension, and associated complications. Despite its common occurrence, the etiology and pathogenesis of liver cirrhosis remain incompletely understood, posing a significant health threat. Effective prevention of its onset and progression is paramount in medical research. Symptoms often include discomfort in the liver area, while complications such as sarcopenia, hepatic encephalopathy, ascites, upper gastrointestinal bleeding, and infection can arise. While the efficacy of Western medicine in treating liver cirrhosis is uncertain, Chinese medicine offers distinct advantages. This review explores advancements in liver cirrhosis treatment encompassing non-pharmacological and pharmacological modalities. Chinese medicine interventions, including Chinese medicine decoctions, Chinese patent medicines, and acupuncture, exhibit notable efficacy in cirrhosis reversal and offer improved prognoses. Nowadays, the combination of Chinese and Western medicine in the treatment of liver cirrhosis also has considerable advantages, which is worthy of further research and clinical promotion. Standardized treatment protocols based on these findings hold significant clinical implications.

Integrative therapy of traditional Chinese medicine and conventional medicine in the treatment of lupus nephritis from a single‐center experience

AbstractLupus nephritis (LN) is the most common complication of systemic lupus erythematosus and the leading cause of mortality. The complex pathogenesis and various clinical manifestations of this disease increase the difficulty of the treatments. The current treatments with Western medicine including glucocorticoids, mycophenolate mofetil and other immunosuppressants, and biological agents have greatly improved the patients' survival. However, frequent recurrence occurred and LN remained an important cause of end stage renal disease. The increasing adverse effects with the prolongation of treatment also restrained the efficacy of Western medicine. Increasing evidence has demonstrated the therapeutic efficacy of traditional Chinese medicine (TCM) which provides a theoretical basis for the integrative therapy of TCM and Western medicine for LN. We previously established a unique comprehensive treatment strategy for LN with the combination of TCM and Western medicine based on the TCM theory and achieved good clinical efficacy. This review will summarize the single‐center experience that integrative therapy of TCM, represented by Lupus Recipe and artesunate, and Western medicine for LN treatment, and elucidate the potential mechanism, with the purpose to provide reliable evidence for developing more effective personalized treatment strategies in the future.

Progress of Chinese and Western Medicine Research on Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a common clinical disease of reproductive endocrine hormone abnormalities and metabolic disorders, with a variety of clinical symptoms and complex etiology. Recent studies have shown that genetics, reproductive endocrine hormones, inflammatory factors, intestinal flora, microRNAs, signal transduction pathways and insulin resistance are closely related to the development of PCOS. Regarding the treatment modalities of PCOS, Western medicine mostly focuses on symptomatic treatment for elevated androgens, ovulation abnormalities, menstrual irregularities and insulin resistance. Chinese medicine focuses on conditioning, and adopts Chinese medicine, acupuncture and needle-medicine combination for different identification and typing through the idea of holistic view. The combination of Chinese and Western medicine gives full play to the advantages between modern medicine and traditional medicine, and combines Western medicine with Chinese medicine for symptomatic treatment, which is a holistic approach and has significant therapeutic effects. Therefore, this paper provides an overview of the research on the etiology and pathogenesis of PCOS in recent years, as well as an overview of the treatment of PCOS by Western medicine, Chinese medicine and the combination of Chinese and Western medicine.

Progress in the Treatment of Ovarian Cysts by Combination of Traditional Chinese and Western Medicine

Ovarian cyst is a common benign tumor in gynecology, often occurring in women of childbearing age. Its essence is a solid or liquid cystic filling structural disease formed inside or on the surface of the ovary, which is not easy to be detected in the early stage, the onset is slow, and serious symptoms and signs such as abdominal fullness, menstrual disorders, and touching mass will occur, affecting women's work and life. At present, both Chinese medicine and Western medicine have certain cognition and advantages in the treatment of ovarian cysts. Chinese medicine can be divided into internal treatment and external treatment, while Western medicine can be divided into drug treatment and surgical treatment. Clinical treatment should be fully considered in the selection of patients' clinical conditions. This paper analyzes the advantages of TCM and Western medicine in clinical treatment, aiming to improve clinical efficacy, reduce cyst recurrence, promote ovarian function recovery, and better protect female ovarian health through the combination of traditional Chinese and Western medicine.

A Case Report on Treating Progressive Supranuclear Palsy with a Combination of Chinese and Western Medicine

A case of progressive supranuclear palsy in a 66-year-old woman is presented. The patient complained of “progressive stiffness of both lower limbs for five years, accompanied by choking and coughing for more than 1 year,” and was diagnosed with paralysis in traditional Chinese medicine (TCM), which was characterized by a deficiency of liver and kidney, and phlegm and blood stasis blocking the collaterals. Western medicine diagnosed it as progressive supranuclear palsy. The patient was diagnosed with “Parkinson’s disease” several times in the past and was given “polybasic hydrazide” and “amantadine hydrochloride tablets,” etc. The patient did not have significant symptomatic relief, so she sought further treatment with a combination of traditional Chinese and Western medicine. Based on the concept of deficiency and excess, this disease is categorized as a paralytic disease in Chinese medicine, and the onset of the disease is closely related to the deficiency of the body after a long period of illness, with wind, phlegm, blood stasis, and deficiency as the main pathogenetic mechanism. The treatment is based on the combination of disease and evidence, with traditional Chinese medicine and acupuncture as the main treatments, supplemented by intermediate-frequency pulsed electrical stimulation, transcranial repetitive magnetic stimulation, medicated canisters, wax therapy, traditional Chinese medicine guasha, and acupoint injections. Western medicine is based on symptomatic treatment, and the patient’s symptoms were relieved significantly after the combination of Chinese and Western medicine.

The combination of tetramethylpyrazine and vitamin A acid in the treatment of skin photoaging by activating the HIF-1α pathway.

Skin photoaging is a skin degenerative disease that causes patients to develop malignant tumors. The existing clinical treatment of photoaging has limitations. This greatly reduces the recovery rate of photoaging patients. Studies have confirmed that Ligusticum wallichii Franch (LWF) monomer tetramethylpyrazine (TMP) alleviates various skin diseases. The combination of traditional Chinese medicine and Western medicine helps with this process. Our research aimed to explore the specific treatment mode and molecular mechanism of TMP in treating skin photoaging. CCK-8 assays were used to evaluate the activity and toxicity of HaCaT cells. β-galactosidase aging, Carbonyl compound and nitrosylated tyrosine assays were used to analyze the aging of HaCaT cells. ROS assays and ELISA were used to analyze the enrichment of ROS. The molecular docking experiment analyzed the binding of TMP and HIF-1α. qRT-PCR and Western blot were used to detect the activation of skin aging-related pathways. HE staining was used to analyze the thickness of the stratum corneum skin on the back skin of mice. 200μg/L LWF alleviates cellular photoaging and mouse skin photoaging by reducing ROS enrichment. Its monomer TMP plays an important role in this process. The combination of TMP and HIF-1α accelerates the degradation of ROS by activating the Nrf2/ARE signaling pathway. This process reduces the apoptosis of cells damaged by light. In addition, we also found that the combination of TMP and retinoic acid (RA) is more beneficial for the treatment of skin damage caused by light in mice. The combination therapy of TMP and RA alleviates skin oxidative stress response through overexpression of HIF-1α. This plan is beneficial for the treatment of skin photoaging.

Combination of Chinese and Western Medicine: Molnupiravir and Lianhua Qingwen in the Treatment of Novel Coronavirus Pneumonia (COVID-19)

Objective: This study aimed to assess the effectiveness of Molnupiravir and Lianhua Qingwen in treating patients with novel coronavirus pneumonia (COVID-19). Materials and Methods: We conducted a study involving 14 cases of COVID-19 infection within a unit group in Laos. During the treatment regimen, these patients received the antiviral drugs Molnupiravir and Lianhua Qingwen as prescribed. We utilized laboratory results of viral nucleic acid tests as observational parameters and statistically analyzed the data using SPSS 26.0 software (linear regression analysis). Our data analysis aimed to determine if there were significant differences in the Ct values of the N gene and ORF1ab gene of SARS-CoV-2 before and after treatment. Results: The results indicated statistically significant differences in the N gene (t =﹣7.014, P &lt; 0.001) and ORF1ab gene (t =﹣7.398, P &lt; 0.001). Post-treatment, the values of the N gene and ORF1ab gene were significantly higher than their pre-treatment values, signifying that the combined utilization of Molnupiravir and Lianhua Qingwen had a substantial impact on the treatment of COVID-19. Conclusion: Molnupiravir and Lianhua Qingwen effectively inhibited the replication of SARS-CoV-2, resulting in a marked improvement in the clinical symptoms of the patients. Laboratory test results also indicated a significant reduction in viral load. These findings provide substantial evidence supporting the efficacy of the combination of Molnupiravir and Lianhua Qingwen in the treatment of COVID-19.

The effects of Nardosinone on levodopa intervention in the treatment of Parkinson's disease

BackgroundThe roots and rhizomes of Nardostachys jatamansi DC. are reported to be useful for the treatment of Parkinson's disease (PD). Previous research has also shown that Nardosinone, the main active component isolated from Nardostachys jatamansi DC., exhibits the potential to treat PD. Aim of the studyTo investigate how the effects of Nardosinone could assist levodopa in the treatment of PD, how this process changes the intestinal flora, and to explore the effective forms of Nardosinone in the intestinal flora. Material and methodsWe used behavioral experiments, and hematoxylin-eosin staining and immunohistochemical staining, to investigate the effects of a combination of Nardosinone and levodopa on rotenone-induced PD rats. In addition, we used LC/MS-MS to determine the levels of levodopa, 5-hydroxytryptamine, dopamine and its metabolite 3, 4-dihydroxyphenylacetic acid, and homovanillic acid, to investigate the effect of the intestinal flora on co-administration in the treatment of PD. LC/MS-MS was also used to detect the metabolites of Nardosinone on the gastrointestinal tract and intestinal flora. ResultsThe behavioral disorders and neuronal damage associated with PD were significantly improved following the co-administration. Analysis also revealed that the co-administration increased the levels of five neurotransmitters in the striatum, plasma and feces. In vitro experiments further demonstrated that the levels of dopamine and levodopa were increased in the intestinal flora. In total, five metabolites of Nardosinone were identified. ConclusionOur findings indicate that Nardosinone and its metabolites might act as a potential adjutant to enhance the efficacy of levodopa via the intestinal flora, thus expanding the therapeutic potential of the combination of Chinese and Western medicine as a treatment method for PD.

An overview of remedial treatment for sudden hearing loss

In the acute phase of sudden hearing loss, in patients for whom two weeks of standardized treatment is ineffective or unsatisfactory, or patients for whom the condition has accumulated for more than three weeks, remedial treatment for about 1 week-1 month can be actively pursued to provide an opportunity for hearing recovery. The mainstay of remedial therapy is intratympanic and retro auricular hormone injections. If the disease has progressed beyond 6 weeks and there is still no significant improvement with local hormone injections, the overall efficacy of the treatment can be improved by a combination of Chinese and Western medicine, such as hyperbaric oxygen chambers, acupuncture, and massage (tui na). However, remedial treatments combining Chinese and Western medicine have not been standardized, and attention should be paid to the diagnosis and treatment during the remedial period.

Evaluation and Monitoring System for Exercise Rehabilitation Based on Combined Chinese and Western Medicine Technology

INTRODUCTION: Developing exercise rehabilitation assessment and monitoring systems is essential in rehabilitation medicine. Introduces a sports rehabilitation assessment and monitoring system based on combining Chinese and Western medicine technology, aiming to integrate traditional Chinese and Western medicine theory and modern Western medicine technology to provide more comprehensive and personalized rehabilitation services. Through the systematic integration of technologies, the author is committed to building an efficient and precise rehabilitation system to provide patients with more scientific and practical rehabilitation programs. OBJECTIVE: The research system employs various sensor technologies, including motion capture devices, biosensors, and pulse recognition technology, by combining Chinese and Western medicine. The motion capture device enables real-time monitoring of the patient's movement trajectory, joint mobility, and other physiological indicators; the biosensor collects the patient's physiological data, such as heart rate and blood pressure. Meanwhile, Chinese and Western medicine pulse recognition technology was introduced to obtain pulse information specific to Chinese and Western medicine to provide more comprehensive data support for rehabilitation assessment. Integrating these technologies, a multi-level and multi-dimensional rehabilitation assessment system was established. METHODS: This study aims to improve the accuracy and personalization of the rehabilitation assessment and to tailor a rehabilitation plan more in line with the patient's actual situation. Through the combination of Chinese and Western medicine techniques, it aims to break the single perspective of traditional rehabilitation assessment and make the rehabilitation plan closer to the physiological characteristics and pathological state of the patients as well as the needs of the combination of Chinese and Western medicine in the identification and treatment. RESULTS: The system has achieved remarkable results in practical application. The accurate monitoring of the motion capture device provides a more comprehensive understanding of the patient's motor status and accurately analyzes the rehabilitation progress. At the same time, the data collection of biosensors provides doctors with more detailed physiological information, enabling them to formulate rehabilitation plans more comprehensively. The introduction of combined Chinese and Western medicine pulse recognition technology adds a unique auxiliary diagnostic tool of collaborative Chinese and Western medicine to the rehabilitation assessment and improves the personalized level of the rehabilitation plan. CONCLUSION: The sports rehabilitation assessment and monitoring system combining Chinese and Western medicine technology brings new ideas and methods for developing rehabilitation medicine. By fully utilizing the advantages of modern technology and traditional medical knowledge, a comprehensive and in-depth rehabilitation assessment system was constructed to provide patients with more scientific and caring rehabilitation services. Future research will optimize the system's performance and promote the broad application of integrated Chinese and Western medicine technology in rehabilitation.

Determinants of Knowledge Sharing Behaviors: Developing and Testing an Integrated Theoretical Model

Hyperprolactinemia is a hypothalamic-pituitary disorder caused by increased serum prolactin levels from a variety of causes. Increased secretion of prolactin (PRL) in the blood can lead to a variety of somatic disorders, including menstrual abnormalities such as scanty or absent menstruation, as well as breast engorgement and infertility. If left untreated, this condition can progress and lead to recurrent miscarriage, embryonic arrest, osteoporotic fractures, and other complications. In recent years, the combination of traditional Chinese medicine and Western medicine has been used to effectively treat hyperprolactinemia. This review aims to provide a comprehensive overview of the treatment of hyperprolactinemia using both traditional and modern medicine, to improve diagnosis and treatment options for this condition.

Research progress of traditional Chinese medicines as quorum sensing inhibitors in collaboration with antibiotics to inhibit drug-resistant bacteria

Quorum sensing system regulates the expression of genes related to bacterial growth, metabolism and other behaviors by sensing bacterial density, and controls the unified action of the entire bacterial population. This mechanism can ensure the normal secretion of bacterial metabolites and the stability of the biofilm microenvironment, providing protection for the formation of biofilms and the normal growth and reproduction of bacteria. Traditional Chinese medicine, capable of quorum sensing inhibition, can inhibit the formation of bacterial biofilms, reduce bacterial resistance, and enhance the anti-infection ability of antibiotics when combined with antibiotics. In recent years, the combination of traditional Chinese and Western medicine in the treatment of drug-resistant bacterial infections has become a research hotspot. Starting with the associations between quorum sensing, biofilm and drug-resistant bacteria, this paper reviews the relevant studies about the combined application of traditional Chinese medicines as quorum sensing inhibitors with antibiotics in the treatment of drug-resistant bacteria. This review is expected to provide ideas for the development of new clinical treatment methods and novel anti-infection drugs.

A Medical Case of Treating Liver Abscess with Combination of Traditional Chinese and Western Medicine

A Medical Case of Treating Liver Abscess with Combination of Traditional Chinese and Western Medicine

Study on the Promotion of Gastrointestinal Function Recovery in Postoperative Patients by the Combination of Traditional Chinese and Western Medicine

Study on the Promotion of Gastrointestinal Function Recovery in Postoperative Patients by the Combination of Traditional Chinese and Western Medicine