You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Prostate & Genitalia1 Apr 20131170 UNDERSTANDING THE MECHANISTIC ROLE OF PAIN APPRAISALS AND BEHAVIOURAL COPING STRATEGIES BETWEEN PAIN AND QUALITY OF LIFE IN CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME (CP/CPPS) Dean A. Tripp, J. Curtis Nickel, Adrijana Koljuskov, Daniel Shoskes, Michel Pontari, Mark S. Litwin, and Mary F. McNaughton-Collins Dean A. TrippDean A. Tripp Kingston, Canada More articles by this author , J. Curtis NickelJ. Curtis Nickel Kingston, Canada More articles by this author , Adrijana KoljuskovAdrijana Koljuskov Kingston, Canada More articles by this author , Daniel ShoskesDaniel Shoskes Cleveland, OH More articles by this author , Michel PontariMichel Pontari Philadelphia, PA More articles by this author , Mark S. LitwinMark S. Litwin Los Angeles, CA More articles by this author , and Mary F. McNaughton-CollinsMary F. McNaughton-Collins Boston, MA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.807AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is characterized by pelvic pain and is largely refractory. Studies have correlated pain, depression, catastrophizing and sedentary behavior on quality of life (QoL) or pain, showing the saliency of psychosocial factors. However, no study has examined a comprehensive list of pain appraisal and behavioural coping strategies as mechanisms in the relationship between pain and QoL. From a self-regulation model, understanding how appraisals and coping interact with outcomes like pain and QoL are important in advancing patient management. METHODS Men (n=168) previously enrolled in the NIH Chronic Prostatitis Cohort study in North American tertiary care centers (6-U.S., 1-Canada) completed a one-time survey of validated self-report measures (QoL:SF-12; demographics; pain: McGill; behavioural pain coping:CPCI; catastrophizing:PCS; Social Support:MSPSS). Data were examined for normality and missing values. Associations of validated pain appraisals (Catastrophizing) and behavioural coping (Illness-focused coping) with outcomes of pain and QoL were examined. Multivariable mediation models tested mediation roles between pain and QoL. RESULTS Multivariable mediation analyses for the relationship between pain and physical QoL was run with mediators of Illness-Focused Coping (IF-coping), Wellness-Focused Coping (WF-coping), Social Support and Catastrophizing showing that only IF-coping was a significant mediator of this relationship (<.001). Follow-up analyses of subscales for IF-coping (Guarding, Resting, Asking for Assistance, Medication Use) showed Guarding was a unique mediator. Mediation analyses between pain and mental QoL was run with mediators of IF-coping, Social Support and Catastrophizing showing support and catastrophizing were significant mediators (<.001). Subscale follow-ups for support (Family, Friends, Significant Other) and Catastrophizing (Rumination, Magnification, Helplessness) showed Friends and Helplessness were unique mediators. CONCLUSIONS These results suggest that IF-coping, Helpless Catastrophic pain appraisals and Friends act as mechanisms that drive and buffer the negative association between pain and QoL indices. Due to the nature of these associations, the hypothesis that symptoms may be physically and mentally disabling through behavioural, cognitive and environmental mechanisms is supported. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e478 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Dean A. Tripp Kingston, Canada More articles by this author J. Curtis Nickel Kingston, Canada More articles by this author Adrijana Koljuskov Kingston, Canada More articles by this author Daniel Shoskes Cleveland, OH More articles by this author Michel Pontari Philadelphia, PA More articles by this author Mark S. Litwin Los Angeles, CA More articles by this author Mary F. McNaughton-Collins Boston, MA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...