Web-based Assessment Research Articles

ChineseCVD: a web-based Chinese-specifi c cardiovascular risk calculator incorporating long COVID, COVID-19vaccination, SGLT2i and PCSK9i treatment effects

Abstract Background Web-based risk prediction tools for cardiovascular diseases are crucial for providing rapid risk estimates for busy clinicians, but there is none available specifically for Chinese subjects. This study developed ChineseCVD, a risk calculator for cardiovascular disease. Methods Adult patients attending government-funded family medicine clinics in Hong Kong between 1st January 2000 and 31st December 2003 were included. The primary outcome was major adverse cardiovascular events (MACE) defined as a composite of myocardial infarction, heart failure, transient ischaemic attacks/ischaemic strokes, and cardiovascular mortality. Results A total of 155,066 patients were used as the derivation cohort. Over a median follow-up of 16.1 (11.6-17.8) years, 31,061 (20.44%) had MACE. Cox regression identified male gender, age, comorbidities, cardiovascular medications, systolic and diastolic blood pressure, and laboratory test results (neutrophil-lymphocyte ratio, creatinine, ALP, AST, ALT, HbA1c, fasting glucose, triglyceride, LDL and HDL) as significant predictors of the above outcomes. ChineseCVD further incorporates the impact of smoking status, COVID-19 infection, number of COVID-19 vaccination doses, and modifier effects of newest medication classes of PCSK9i and SGLT2i. The calculator enables clinicians to demonstrate to patients how risks vary with different medications. Conclusions The ChineseCVD risk calculator enables rapid web-based risk assessment for adverse cardiovascular outcomes, thereby facilitating clinical decision-making at the bedside or in the clinic.

Coefficients of variation analyses of internal quality control status for blood lead in China from 2015 to 2023.

Blood lead test is widely conducted in Chinese laboratories, while the imprecision of blood lead measurement based on internal quality control (IQC) across China has not been comprehensively evaluated nowadays. Using the IQC data of blood lead collected through a web-based external quality assessment (EQA) reporting system, we analyzed current coefficients of variation (CVs) of blood lead from 2015 to 2023 among Chinese laboratories. Two allowable total error (TEa) imprecision levels from EQA were applied to calculate the pass rates, namely percentages of laboratories meeting precision quality specifications. Besides, CV values and pass rates by different subgroups were further performed to assess potential differences. Generally, median CV values significantly declined year by year from 6.8% in February 2015 to 5.9% in March 2023. The pass rates based on 1/3 TEa showed upward trends increasing from 15.3% in February 2015 to 20.0% in March 2023, but these percentages were non-ideal with less than 25%. No significant differences in CVs were found between tertiary hospitals and non-tertiary hospitals and between accredited and non-accredited laboratories. Significant time trends were observed in tertiary hospitals and nonaccredited laboratories. As for manufacturers, Bohui and self-made QC sample were most widely-used with obvious interannual declining trends of CVs. The CVs of blood lead demonstrated continuous overall improvements in the past twenty years. However, relatively lower pass rates indicated the non-ideal imprecision performance, and more proper performance specifications are warranted. Thus, imprecision improvement and ongoing investigation for blood lead IQC are still needed.

Evaluating User Experiences and Preferred Features of a Web-Based 24-Hour Dietary Assessment Tool: Usability Study.

Intake24, a web-based 24-hour dietary recall tool developed in the United Kingdom, was adapted for use in New Zealand (Intake24-NZ) through the addition of a New Zealand food list, portion size images, and food composition database. Owing to the customizations made, a thorough evaluation of the tool's usability was required. Detailed qualitative usability studies are well suited to investigate any challenges encountered while completing a web-based 24-hour recall and provide meaningful data to inform enhancements to the tool. This study aims to evaluate the usability of Intake24-NZ and identify improvements to enhance both the user experience and the quality of dietary intake data collected. We used a mixed methods approach comprising two components: (1) completion of a single 24-hour dietary recall using Intake24-NZ with both screen observation recordings and collation of verbal participant feedback on their experience and (2) a survey. A total of 37 participants aged ≥11 years self-completed the dietary recall and usability survey (men and boys: 14/37, 38% and women and girls: 23/37, 62%; Māori: 10/37, 27% and non-Māori: 27/37, 73%). Although most (31/37, 84%) reported that Intake24-NZ was easy to use and navigate, data from the recorded observations and usability survey revealed challenges related to the correct use of search terms, search results obtained (eg, type and order of foods displayed), portion size estimation, and associated food prompts (eg, did you add milk to your tea?). This comprehensive usability study identified challenges experienced by users in completing a dietary recall in Intake24-NZ. The results informed a series of improvements to enhance user experience and the quality of dietary data collected with Intake24-NZ, including adding new foods to the food list, optimizing the search function and ordering of search results, creating new portion size images, and providing clearer instructions to the users.

Association between cognitive reserve proxies and frailty phenotype: data from UK Biobank.

A potential protective role of cognitive reserve proxies against frailty has been suggested in older adults. We explored the cross-sectional association between cognitive reserve indicators and frailty phenotype. Data were obtained from the UK Biobank. We included 31,975 dementia-free participants aged ≥ 60years (50.7% females, 2.2% frail) who completed a web-based cognitive assessment (fluid intelligence, working memory, visuospatial attention and processing speed, and executive functioning). Frailty was defined according to the Fried's phenotype (unintentional weight loss, exhaustion, low physical activity, slowness, and weakness). Participants meeting three or more criteria were classified as frail. Cognitive performance was compared between nonfrail and frail groups, and regression models were employed to analyze the associations between cognitive reserve proxies (education, skill level of occupation, social support, and multiple deprivation index (MDI)) and the likelihood of frailty. Frail and nonfrail groups significantly differed on cognitive function, with frail individuals demonstrating poorer performance on all cognitive functions (all p < .05) except fluid intelligence. Regression analysis showed that, after adjusting for age and sex, a lower educational level (odds ratio (OR) .797, 95% confidence interval (CI) .673-.944, p = .009), having maintained occupations with low cognitive requirements (OR .790, 95% CI .668-.936, p = .006), having less social support (OR .755, 95% CI .631-.903, p = .002), and living in a region with a high rate of multiple deprivation (OR 1.025, 95% CI 1.019-1.031, p < .001), significantly increased the probability of experiencing frailty. Our findings support the relationship between declined cognitive functions and frailty emphasizing the importance of implementing public health measures to enhance cognitive reserve.

Development of a web-based ecological momentary assessment tool to measure day-to-day variability of the symptoms in patients with Sjögren’s disease

ObjectivesTo develop and validate a web-based ecological momentary assessment (EMA) tool to enhance symptoms monitoring among patients with Sjögren’s disease (SjD).MethodsConsecutive adults with SjD were enrolled in this pilot observational...

Web-Based Assessment System for Graduate Learning Achievements in Outcome-Based Education

This research utilizes the Rapid Application Development (RAD) approach, with the analysis stage involving a review of relevant literature and interviews with prospective system users. The next stage is the requirement planning, which entails defining the features or services within the software accessible to prospective system users. The design phase employs use case diagrams, activity diagrams, and Entity Relationship Diagrams (ERD). Subsequently, it is translated into the Laravel framework and undergoes testing to produce a software system for assessing Graduate Learning Outcomes (CPL). This system offers facilities for academic programs to create outcome-based education (OBE) mappings and enables instructors to assess students based on the established mapping data. It also provides students with the ability to view their outcome results. CPL refer to the essential skills that students must acquire following their academic studies. These skills encompass the internalization of grades, attitudes, general knowledge, and specific skills, which students are required to fulfill throughout their academic journey. Outcome grades, as mapped, are attained by students through participation, written tests (quizzes), observations (practical exercises), performance (presentations), mid-term exams, final exams, and oral tests (group assignments). This Graduate Learning Outcomes assessment software is expected to assist program administrators and instructors in managing CPL and also enable students to access detailed records of their outcome grades.

Is a web-based Thai version of the work-related quality of work-life scale-2 a reasonable alternative to the paper-based version?

ABSTRACT This study investigates the suitability of a Thai web-based assessment tool for comprehensively evaluating the Work-Related Quality of Life (WRQoL). A descriptive study was conducted. The web-based questionnaire was distributed to health workers at the University Hospital of the Faculty of Medicine at Khon Kaen University, Khon Kaen, Thailand, via convenience sampling, yielding 290 usable responses after data cleaning. IBM SPSS and AMOS performed Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA). The results revealed enhanced internal consistency upon excluding 1 item (Q24) and delineated dimensions into 5 categories: homework interface and working conditions web-based (HWCW), web-based job and career satisfaction (JCSW), web-based general well-being (GWBW), web-based control at work (CAWW), and web-based stress at work (SAWW). This web-based assessment tool has potential advantages in technological convenience and interpretation accuracy. It offers a robust framework for assessing WRQoL dimensions and advancing workplace well-being assessment methodologies.

Addressing the climate adaptation tracking gap: an assessment method and its application to the Caribbean region

This article addresses the climate adaptation tracking gap. Indeed, we still ignore the intensity, nature, spatial distribution, effectiveness, and recent evolution of adaptation efforts at the national, regional, and global scales. We propose a web-based replicable assessment method using key variables to document adaptation efforts: country/territory, location, goal, implementation date, type of action, holder, funding source. Applying it to the Caribbean region, we analyzed 100 coastal adaptation actions. This studies the method while also highlighting the difficulties faced to track adaptation. We found that coastal adaptation efforts are substantial and increasing in the Caribbean, revealing the use of diversified adaptation actions; prevalence of hard protection (51%); increase use of Nature-based Solutions (22%); limited use of retreat (6%); and accommodation (2%). Combined actions (17%) increased over time, due to the failure of single actions and need to find tradeoffs between human asset protection encouraging hard protection and the maintenance of attractive tourist beaches encouraging beach nourishment. Puerto Rico and Trinidad and Tobago fall under the engineering-based “one-size-fits-all” adaptation model, whereas Jamaica and Barbados experiment diversified options and combinations of options. Jamaica, Puerto Rico, Trinidad and Tobago, and Barbados are particularly active in taking adaptation action, while most dependent islands and sub-national island jurisdictions have no adaptation action reported. Considering the advantages and limitations of a web-based method compared to a field-based approach, we recommend the combined use of these two complementary approaches to support adaptation tracking and help structuring communities of practice to the benefits of decision-makers and practitioners and scholars.

A - 15 Convergent Validity between Standard Neuropsychological Assessment and Web-Based Voice-Recognition Neuropsychological Assessment (Intraneuron)

Abstract Objective The prevalence of mild cognitive impairment (MCI) remains high, and often cases may go undetected. The gold standard for detection of cognitive decline is neuropsychological assessment. However, access to neuropsychological assessment can be impacted by geographic and financial limitations. Prior research has determined that electronic-based testing is effective in detecting cognitive change. This study aimed to investigate a convergent validity between standard neuropsychological assessment (SNA) and a web-based, voice-recognition neuropsychological assessment tool (Intraneuron). Method 75 participants from a community-based neurology practice completed SNA and Intraneuron. Intraneuron is comprised of an auditory list learning/recall test and verbal fluency tests (F/A/S, animals). Pearson correlations were conducted to examine the convergent validity between SNA and Intraneuron. A McNemar cross tabulation analysis was utilized to compare the proportions of detected “normal” and “abnormal” screening for SNA (based on clinical diagnosis) and Intraneuron (utilizing 1SD and 1.5SD below the mean as cutoffs). Results There were moderate, positive correlations between the SNA and Intraneuron: animals (r = 0.43, p &amp;lt; 0.001), F/A/S (r = 0.67, p &amp;lt; 0.001), delayed word list recall (r = 0.49, p &amp;lt; 0.001). The McNemar test showed that the classification between SNA and Intraneuron were similar at 1SD and 1.5SD. Conclusions The study demonstrated convergent validity SNA and Intraneuron. Results suggest that the Intraneuron is equivalent in the detection of early cognitive decline compared to SNA. This data provides support for the value of a web-based screening tool and the potential to maximize utilization across multiple settings and improve early detection of cognitive decline.

Web-based objective and structured assessment of point-of-care lung ultrasound skills in resource-limited settings

BackgroundObjective assessment of skills after training is essential for safe implementation of lung point-of-care ultrasound (POCUS). In low-and middle-income countries (LMIC) there is a need for assessment tools without onsite experts to scale up POCUS access. Our objective is to develop a web-based assessment tool and evaluate trainees across different countries and at different time points after initial lung POCUS training.MethodsWe adapted the objective and validated lung ultrasound score (LUS-OSAUS) to a web-based tool with quiz and practical skills test. Trainees were evaluated after a short (4-day) standardized lung POCUS training and were classified in distinct groups according to (i) their geographical location (Benin vs. South-Africa) and (ii) time elapsed since training (Benin 0 months vs. Benin 6 months). The Benin 6 months group had minimal continuous education. Skills test images were read by two blinded experts. We report the overall success rates and then compare these rates based on location and timing since training, using the Fischer’s exact test.ResultsA total of 35 out of 43 participants completed the online LUS-OSAUS quiz and skills test. The overall success rate was 0.84 (95%CI 0.80–0.88), with lower success rates for “correct depth” 0.54 (0.37–0.71), “correct assessment of pleura” 0.63 (0.45–0.79) and “conclusion” 0.71 (0.54–0.85). There were no differences based on location, with respective rates of 0.86 (0.80–0.92) and 0.83 (0.75–0.91) (p-value = 0.125) for Benin and South Africa at 0 months, respectively. Similarly, there were no differences according to timing with success rates of 0.86 (0.80–0.92) and 0.82 (0.72–0.93) (p-value = 0.563) for Benin at 0 months and 6 months, respectively.ConclusionWeb-based objective and structured assessment of lung POCUS skills in LMIC following a short-standardized training is feasible and has a good overall success rate with consistent results across regions and up to 6 months after training given minimal continuous education. Overall, technical and POCUS-based clinical conclusion skills are the most difficult to acquire.

Unleashing frailty from laboratory into real world: A critical step toward frailty-guided clinical care of older adults.

Understanding patients' degree of frailty is crucial for tailoring clinical care for older adults based on their physiologic reserve and health needs ("frailty-guided clinical care"). Two prerequisites for frailty-guided clinical care are: (1) access to frailty information at the point of care and (2) evidence to inform decisions based on frailty information. Recent advancements include web-based frailty assessment tools and their electronic health records integration for time-efficient, standardized assessments in clinical practice. Additionally, database frailty scores from administrative claims and electronic health records data enable scalable assessments and evaluation of the effectiveness and safety of medical interventions across different frailty levels using real-world data. Given limited evidence from clinical trials, real-world database studies can complement trial results and help treatment decisions for individuals with frailty. This article, based on the Thomas and Catherine Yoshikawa Award lecture I gave at the American Geriatrics Society Annual Meeting in Long Beach, California, on May 5, 2023, outlines our group's contributions: (1) developing and integrating a frailty index calculator (Senior Health Calculator) into the electronic health records at an academic medical center; (2) developing a claims-based frailty index for Medicare claims; (3) applying this index to evaluate the effect of medical interventions for patients with and without frailty; and (4) efforts to disseminate frailty assessment tools through the launch of the eFrailty website and the forthcoming addition of the claims-based frailty index to the Centers for Medicare and Medicaid Services Chronic Conditions Data Warehouse. This article concludes with future directions for frailty-guided clinical care.

Correlates of lifestyle patterns among children in Singapore aged 10 years: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study

ObjectiveTo characterise lifestyle patterns (comprising dietary and movement behaviour aspects) of children in Singapore and examine the correlates of these patterns.DesignAn observational study approach was used. Children recorded their diet and activities over two weekdays and two weekend days on a validated web-based assessment, My E-Diary for Activities and Lifestyle (MEDAL). Lifestyle patterns were derived using principal component analysis, and the correlations of these with multiple known determinants organised by distal, intermediate, and proximal levels of influence were studied.SettingChildren of the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort.ParticipantsTen-year-old children (n = 397).ResultsThree lifestyle patterns, “high snacks and processed food”, “balanced” and “mixed”, were identified. We focused on the more health-promoting “balanced” pattern, characterised by lower screen-viewing and higher consumption of fruits, vegetables, wholegrains, and dairy. Among the distal factors, girls were more adherent to the “balanced” pattern compared to boys, and children of parents with lower education levels were less adherent to this pattern. Among intermediate factors, children of mothers with higher diet quality were more adherent to the “balanced” pattern. Among the proximal factors, engagement in active transport, leisure sports, and educational activities outside of school were positively associated with the “balanced” pattern, whereas screen-viewing while travelling was negatively associated with this pattern. Having siblings, pet ownership, mother’s physical activity, parenting style, parental bonding, child’s outdoor time, and breakfast consumption were not associated with children’s lifestyle patterns.ConclusionsThese findings provide direction for future interventions by identifying vulnerable groups and contexts that should be prioritised.

Practical Application of Assessment Theories for English Teacher through Digital Technologies

Digital technology has revolutionized educational quality, particularly in English as a Foreign Language (EFL) classrooms. This article examines the benefits and challenges of using web-based applications such as Kahoot, Quizizz, Google Apps, and Nearpod for assessments. These tools offer innovative alternatives to traditional methods by enabling dynamic evaluation of student progress, providing real-time feedback, and creating engaging learning experiences. However, challenges such as internet connectivity issues, technological proficiency gaps, and the need for adequate devices can hinder their effectiveness. This paper provides guidelines for optimizing digital assessments, including assessing students' proficiency levels, setting realistic deadlines, ensuring equitable access to technology, and selecting appropriate platforms. The methodology comprises a thorough review and analysis of existing literature on digital tools in EFL classrooms, emphasizing the benefits and challenges of web-based assessment applications. By following these guidelines, educators can design assessments that are valid, reliable, fair, and transparent, thus enhancing teaching strategies and student outcomes. The article also highlights the importance of understanding various assessment types—initial, formative, and summative—and tailoring digital tools to meet specific EFL education objectives. By leveraging digital technologies, educators can improve the assessment process, ultimately contributing to a more effective and successful teaching and learning experience.

Validation of an web-based dietary assessment tool (RiksmatenFlex) against doubly labelled water and 24 h dietary recalls in pregnant women

IntroductionDigital technologies have enabled new possibilities to assess dietary intake and have shown promise in terms of decreased participant burden, improved accuracy and lower costs. However, their potential and validity in pregnant populations are scarcely explored.ObjectivesThis study aimed to (a) validate energy intakes obtained from a web-based dietary recall method developed for national surveys (RiksmatenFlex) against total energy expenditure (TEE) by means of the doubly labelled water (DLW) method, and (b) to compare intakes of macronutrients, key unhealthy and healthy foods as well as adherence to food-based dietary guidelines between RiksmatenFlex and repeated 24 h telephone dietary recalls in healthy Swedish pregnant women.MethodsThis study was conducted as a nested validation within the HealthyMoms trial. Intakes of foods, macronutrients and energy were assessed during three days through RiksmatenFlex and 24 h telephone dietary recalls, and Swedish Healthy Eating Index (SHEI) scores were also calculated for both methods (n = 52). For 24 women, TEE was also assessed through the DLW method. Paired Samples T-tests and Wilcoxon Signed Ranks Tests were used to identify differences between means for foods, macronutrients, energy and SHEI scores. Pearson correlation coefficient or Spearman’s rho were performed to identify relationships between variables. To compare energy intake (RiksmatenFlex) with TEE (DLW method) and 24 h telephone dietary recalls, Bland and Altman plots were constructed.ResultsAverage energy intake from RiksmatenFlex (10,015 [SD 2004] kJ) was not statistically different from TEE (10,252 [SD 1197] kJ) (p = 0.596) (mean difference: -237 kJ/24 h). Correspondingly, there were small mean differences between average intakes of key unhealthy and healthy foods and average SHEI scores between RiksmatenFlex and 24 h telephone dietary recalls. However, the Bland and Altman plots showed wide limits of agreement for all dietary variables (e.g., for energy intake using RiksmatenFlex versus TEE: ±4239 kJ/24 h). High correlations between the investigated dietary variables for the two dietary methods were observed (r = 0.751 to 0.931; all p < 0.001).ConclusionRiksmatenFlex captured average intakes of energy, unhealthy and healthy food groups and adherence to food-based dietary guidelines in a comparable way to 24 h telephone dietary recalls and the DLW method. Our results support the validity of RiksmatenFlex as a web-based dietary assessment method for future use in pregnancy for intervention studies and national dietary surveys.

Deliberate Practice as an Effective Method for Reducing Diagnostic Error in Identifying Burn and Bruise Injuries Suspicious for an Abusive Injury

To examine the effectiveness of an education intervention for reducing physician diagnostic error in identifying pediatric burn and bruise injuries suspicious for abuse, and to determine case-specific variables associated with an increased risk of diagnostic error. This was a multicenter, prospective, cross-sectional study. A convenience sample of pediatricians and other front-line physicians who treat acutely injured children in the United States and Canada were eligible for participation. Using a web-based education and assessment platform, physicians deliberately practiced with a spectrum of 300 pediatric burn and bruise injury image-based cases. Participants were asked if there was a suspicion for abuse present or absent, were given corrective feedback after every case, and received summative diagnostic performance overall (accuracy), suspicion for abuse present (sensitivity), and absent (specificity). Of the 93/137 (67.9%) physicians who completed all 300 cases, there was a significant reduction in diagnostic error (initial 16.7%, final 1.6%; delta -15.1%; 95% CI 13.5, 16.7), sensitivity error (initial 11.9%, final 0.7%; delta -11.2%; 95% CI 9.8, 12.5), and specificity error (initial 23.3%, final 6.6%; delta -16.7%; 95% CI 14.8, 18.6). Based on 35,627 case interpretations, variables associated with diagnostic error included patient age, sex, skin color, mechanism of injury, and size and pattern of injury. The education intervention substantially reduced diagnostic error in differentiating the presence versus absence of a suspicion for abuse in children with burn and bruise injuries. Several case-based variables were associated with diagnostic error, and these data can be used to close specific skill gaps in this clinical domain.

"Boosting Students' Engagement with Web-Based Assessment Platforms: A Self-Determination Theory Perspective"

"Boosting Students' Engagement with Web-Based Assessment Platforms: A Self-Determination Theory Perspective"

Applying Meaning and Self-Determination Theory to the Development of a Web-Based mHealth Physical Activity Intervention: Proof-of-Concept Pilot Study.

Meaning in life is positively associated with health, well-being, and longevity, which may be partially explained by engagement in healthier behaviors, including physical activity (PA). However, promoting awareness of meaning is a behavior change strategy that has not been tested in previous PA interventions. This study aims to develop, refine, and pilot-test the Meaningful Activity Program (MAP; MAP to Health), a web-based mobile health PA intervention, theoretically grounded in meaning and self-determination theory, for insufficiently active middle-aged adults. Following an iterative user-testing and refinement phase, we used a single-arm double baseline proof-of-concept pilot trial design. Participants included 35 insufficiently active adults in midlife (aged 40-64 years) interested in increasing their PA. After a 4-week baseline period, participants engaged in MAP to Health for 8 weeks. MAP to Health used a web-based assessment and just-in-time SMS text messaging to individualize the intervention; promote meaning salience; support the basic psychological needs of autonomy, competence, and relatedness; and increase PA. Participants completed measures of the hypothesized mechanisms of behavior change, including meaning salience, needs satisfaction, and autonomous motivation at pretest (-4 weeks), baseline (0 weeks), midpoint (4 weeks), and posttest (8 weeks) time points, and wore accelerometers for the study duration. At the end of the intervention, participants completed a qualitative interview. Mixed models compared changes in behavioral mechanisms during the intervention to changes before the intervention. Framework matrix analyses were used to analyze qualitative data. Participants were aged 50.8 (SD 8.2) years on average; predominantly female (27/35, 77%); and 20% (7/35) Asian, 9% (3/35) Black or African American, 66% (23/35) White, and 6% (2/35) other race. Most (32/35, 91%) used MAP to Health for ≥5 of 8 weeks. Participants rated the intervention as easy to use (mean 4.3, SD 0.8 [out of 5.0]) and useful (mean 4.3, SD 0.6). None of the hypothesized mechanisms changed significantly during the preintervention phase (Cohen d values <0.15). However, autonomy (P<.001; Cohen d=0.76), competence (P<.001; Cohen d=0.65), relatedness (P=.004; Cohen d=0.46), autonomous motivation (P<.001; Cohen d=0.37), and meaning salience (P<.001; Cohen d=0.40) increased significantly during the intervention. Comparison of slopes before the intervention versus during the intervention revealed that increases during the intervention were significantly greater for autonomy (P=.002), competence (P<.001), and meaning salience (P=.001); however, slopes were not significantly different for relatedness (P=.10) and autonomous motivation (P=.17). Qualitative themes offered suggestions for improvement. MAP to Health was acceptable to participants, feasible to deliver, and associated with increases in the target mechanisms of behavior change. This is the first intervention to use meaning as a behavior change strategy in a PA intervention. Future research will test the efficacy of the intervention in increasing PA compared to a control condition.

Reproducibility of a Web-Based Dietary Assessment Tool—myfood24®—In a Danish Population: A Repeated Cross-Sectional Validation Study

Reproducibility of a Web-Based Dietary Assessment Tool—myfood24®—In a Danish Population: A Repeated Cross-Sectional Validation Study

Biological Validity of a Web-Based Dietary Assessment Tool—myfood24®—In a Danish Population: A Cross-Sectional Validation Study

Biological Validity of a Web-Based Dietary Assessment Tool—myfood24®—In a Danish Population: A Cross-Sectional Validation Study

Continuous Associations between Remote Self-Administered Cognitive Measures and Imaging Biomarkers of Alzheimer’s Disease

BackgroundEasily accessible and self-administered cognitive assessments that can aid early detection for Alzheimer’s disease (AD) dementia risk are critical for timely intervention.Objectives/DesignThis cross-sectional study investigated continuous associations between Mayo Test Drive (MTD)–a remote, self-administered, multi-device compatible, web-based cognitive assessment–and AD-related imaging biomarkers.Participants/Setting684 adults from the Mayo Clinic Study of Aging and Mayo Clinic Alzheimer’s Disease Research Center participated (age=70.4±11.2, 49.7% female). Participants were predominantly cognitively unimpaired (CU; 94.0%).MeasurementsParticipants completed (1) brain amyloid and tau PET scans and MRI scans for hippocampal volume (HV) and white matter hyperintensities (WMH); (2) MTD remotely, consisting of the Stricker Learning Span and Symbols Test which combine into an MTD composite; and (3) in-person neuropsychological assessment including measures to obtain Mayo Preclinical Alzheimer’s disease Cognitive Composite (Mayo-PACC) and Global-z. Multiple regressions adjusted for age, sex, and education queried associations between imaging biomarkers and scores from remote and in-person cognitive measures.ResultsLower performances on MTD were associated with greater amyloid, entorhinal tau, and global tau PET burden, lower HV, and higher WMH. Mayo-PACC and Global-z were associated with all imaging biomarkers except global tau PET burden. MCI/Dementia participants showed lower performance on all MTD measures compared to CU with large effect sizes (Hedge’s g’s=1.65–2.02), with similar findings for CU versus MCI only (Hedge’s g’s=1.46–1.83).ConclusionMTD is associated with continuous measures of AD-related imaging biomarkers, demonstrating ability to detect subtle cognitive change using a brief, remote assessment in predominantly CU individuals and criterion validity for MTD.