Integrating quantum key distribution (QKD) with classical optical communication is a deployment-friendly and cost-effective approach to advancing QKD network implementation. However, the noise introduced by intense classical signals into the quantum channel severely impacts the performance of the QKD system, presenting challenges for long-distance coexistence transmission. In this paper, we successfully demonstrate the simultaneous propagation of QKD and optical transport network (OTN) in the C-band over distances exceeding 100 km. We establish a coexistence transmission system based on a commercial OTN equipment and QKD device equipped with the Fabry-Perot filters, demonstrating the feasibility of combining QKD with 11 Tbps (110×100 Gbps) classical data over a 101.86 km fiber. To investigate longer transmission distances, we employ an optimized wavelength allocation method and conduct the co-propagation of QKD and 1 Tbps classical data over a 152.34 km fiber. To the best of our knowledge, these results are the first time that report the integration of QKD and large-capacity classical communication over hundred-kilometer scale fiber. Our works represent a significant advancement in developing OTN networks incorporating QKD systems.