Water Solutions Of Compounds Research Articles

Quinoline Derivatives as Growth Regulators for Ornamental Plants

It is investigated the effect of synthesized organic compounds of 6-hydroxy-2,2,4-trimethyl-1,2- dihydroquinoline, its derivatives, and hydrogenated analogs. These compounds affected the height of seedlings when they were used for pre-sowing seed treatment of the following ornamental plants: annual ornamental grass – scarlet sage (Salvia splendens) and woody plant – yellow rhododendron (Rhododendron luteum). Prior to the sprouting process, the seeds of Rh. luteum and S. splendens were soaked in water solutions of compounds with concentrations of 0.01%, 0.05%, and 0.1% for 18 hours. Dihydro- and tetrahydroquinolines with a concentration of 0.05% proved to be the most effective for both plants. For Rhododendron luteum, the compounds of 6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline, its derivatives, and hydrogenated analogs with a concentration of 0.1% proved to be the most effective. Dihydroquinolines at concentrations of 0.05 and 0.1% proved to have the strongest effect when applied to the studied perennial woody plant (Rhododendron luteum). Dihydroquinoline at the concentration of 0.05% also proved to be effective when applied to the annual grass (Salvia splendens). For annual S. splendens, tetrahydroquinoline at concentrations of 0.01 and 0.05% appeared to be the most effective. The pre-sowing seed treatment of grass Salvia splendens and woody plant Rhododendron luteum with the studied compounds demonstrated that their effect on the height of the seedlings is species-specific. The pre-sowing seed treatment of Rh. luteum and S. splendens allows increasing the height of the seedlings by 3-61 % and 17-25 %, respectively. It is suggested using the compounds of 6-hydroxy-2,2,4- trimethyl-1,2-dihydroquinoline, its derivatives, and hydrogenated analogs as effective growth stimulators for ornamental grasses and woody plants

QUINOLINE DERIVATIVES AS GROWTH REGULATORS FOR ORNAMENTAL PLANTS

It is investigated the effect of synthesized organic compounds of 6-hydroxy-2,2,4-trimethyl-1,2- dihydroquinoline, its derivatives, and hydrogenated analogs. These compounds affected the height of seedlings when they were used for pre-sowing seed treatment of the following ornamental plants: annual ornamental grass – scarlet sage (Salvia splendens) and woody plant – yellow rhododendron (Rhododendron luteum). Prior to the sprouting process, the seeds of Rh. luteum and S. splendens were soaked in water solutions of compounds with concentrations of 0.01%, 0.05%, and 0.1% for 18 hours. Dihydro- and tetrahydroquinolines with a concentration of 0.05% proved to be the most effective for both plants. For Rhododendron luteum, the compounds of 6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline, its derivatives, and hydrogenated analogs with a concentration of 0.1% proved to be the most effective. Dihydroquinolines at concentrations of 0.05 and 0.1% proved to have the strongest effect when applied to the studied perennial woody plant (Rhododendron luteum). Dihydroquinoline at the concentration of 0.05% also proved to be effective when applied to the annual grass (Salvia splendens). For annual S. splendens, tetrahydroquinoline at concentrations of 0.01 and 0.05% appeared to be the most effective. The pre-sowing seed treatment of grass Salvia splendens and woody plant Rhododendron luteum with the studied compounds demonstrated that their effect on the height of the seedlings is species-specific. The pre-sowing seed treatment of Rh. luteum and S. splendens allows increasing the height of the seedlings by 3-61 % and 17-25 %, respectively. It is suggested using the compounds of 6-hydroxy-2,2,4- trimethyl-1,2-dihydroquinoline, its derivatives, and hydrogenated analogs as effective growth stimulators for ornamental grasses and woody plants.

Design, synthesis and biological evaluation of carbohydrate-based sulphonamide derivatives as topical antiglaucoma agents through selective inhibition of carbonic anhydrase II

A series of new carbohydrate-based sulphonamide derivatives were designed, synthesised by employing the so-call ‘sugar-tail’ approach. The compounds were evaluated in vitro against a panel of CAs. Compared to their parent compound p-sulfamoylbenzoic acid, these compounds showed nearly 100-fold improvement in their binding affinities against hCA II in vitro. All of compounds showed great water solubility and the pH value of their water solutions of compounds is 7.0. Such properties are advantageous to make them much less irritating to the eye when applied topical glaucomatous drugs, compared to the relatively highly acidic dorzolamide preparations (pH 5.5). Notably, compounds 7d, 7 g, 7 h demonstrated to topically lower intraocular pressure (IOP) in glaucomatous animals better than brinzolamide when applied as a 1% solution directly into the eye. Low cytotoxicity on human cornea epithelial cell was observed in the tested concentrations by the MTT assay.