The fracturedlow permeability reservoirs develop complex fracture network. As the of waterflooding recovery heightens, excessive high injection pressures and excessive water injection rate will result in open, initiation, propagation and coalescence of microfracture, connecting injection with production form the high permeability zone, which results in a one-way onrush of waterflooding, water cut in oil well water rise quickly, causing a severe oil well flooding and channeling, thereby reducing the ultimate oil recovery efficiency. The effect of the waterflooding seepage within natural fracture on fracture initiation is studied and analyzed here, applying the theory of rock fracture mechanics to analyze the interaction of fracture system for naturally fractured reservoirs in waterflooding developing process, studying the mechanical mechanism of opening, initiation, propagation and coalescence of natural fracture under injection pressure, which is important theoretical significance for studying the distribution law of fracture and defining appreciate water injection mode and injection pressure in the process of injection development of the naturally fractured reservoir and for delaying the directivity water break-through and water flooding rate of oil well in the process of injection development.