Ethanol-water Solution Research Articles

Arabic gum-grafted-polyaniline@MnFe2O4/UIO66-NH2 bionanocomposite as adsorbent for quercetin antioxidant: Efficiency, kinetics, thermodynamics and isotherm modelling

Quercetin is one of the most powerful antioxidants in nature and a major dietary flavonoid, so its efficient recovery by nanoadsorbents can be valuable for human health. In this study, the nanocomposite Arabic gum-grafted-polyaniline@MnFe2O4/UIO66-NH2 (AG-g-PANI@MnFe2O4/UIO66-NH2) was synthesized by in situ copolymerization. The physicochemical and structural properties of the AG-g-PANI@MnFe2O4/UIO66-NH2 nanocomposite were examined using various methods, including XRD, FE-SEM, FT-IR, EDX, VSM, TGA, and BET. The adsorption capacity of natural nanoadsorbent was evaluated for the adsorption of quercetin antioxidant from an ethanol-water solution (50 % v/v) in a batch system. The influence of controlling factors such as solution pH, adsorbent dose, contact time, initial quercetin concentration and temperature on the adsorption process was investigated. The highest adsorption capacity (9.1157 mg.g−1) was achieved at a pH of 8, with 0.025 g of adsorbent, a quercetin solution concentration of 20 mg.L−1, a 300 min contact time and at the temperature 298.15 K. In addition, the data from adsorption experiments were analyzed using different isotherm and kinetic models. The findings demonstrated that the Temkin isotherm and the pseudo-second-order kinetic model are the most suitable for representing the adsorption behavior. In addition, from analysis of the temperature effect was found that the adsorption of quercetin on AG-g-PANI@MnFe2O4/UIO66-NH2 is a spontaneous (∆G° < 0) and exothermic (ΔH° < 0) process. Finally, the reusability of nanoadsorbent and desorption kinetics of quercetin were investigated and it was specified that AG-g-PANI@MnFe2O4/UIO66-NH2 can be effectively renewed and recycled, maintaining its adsorption efficacy without significant reduction after five repeated cycles.

Sorption thermodynamic and kinetic study of Cu(II) onto modified plant stem bark.

In this study, four types of "Juá" stem barks (Ziziphus joazeiro) were investigated for the removal of Cu(II) from aqueous solutions. The tested samples included natural coarse barks, and barks washed with water, ethanol-water, and NaOH solutions. The solvent-modified materials simulated the waste of the industrial extraction of saponins from bark. The valorization of these processing residues as sorbents was evaluated. The NaOH-washed sorbent exhibited the highest sorption capacity for Cu(II) (maximum sorption capacity 32mgg-1). Ion exchange process between copper and exchangeable surface cations and electrostatic attraction of copper with carboxylate and phenolate groups were identified as the primary sorption mechanisms. Desorption tests revealed that a large portion of the metal sorbed (80%) was easily released from the sorbent thus suggesting, in line with the proposed mechanisms, the existence of weak sorbate-sorbent interactions. The sorptive process was found to be exothermic (∆H° = - 48.1 ± 13.5kJ.mol-1) and thermodynamically favorable at lower temperatures.

Solubility effect of deep eutectic solvent and ethanol concentration on corncob lignin extraction

This research investigates the solubility effect of deep eutectic solvent (DES) mass ratio and ethanol–water solution concentration on corncob lignin extraction. The objective is to propose a solubility matching technique based on like-dissolves-like theory to optimize lignin extraction conditions. The choline chloride (ChCl):lactic acid (LA) mass ratio that maximized lignin extraction was determined by varying DES mass ratio between 1:2 and 1:5, and ethanol–water solution (5–95 % (v/v)) was added to precipitate lignin. By using the solubility matching technique, the maximum lignin extraction was achieved at 1:4 ChCl:LA mass ratio, and 70 % (v/v) ethanol–water concentration yielded the highest lignin precipitation. Lignin is highly soluble where the solubility (δ-values) of lignin, DES, and precipitant are similar. Unlike conventional trial-and-error methods, the solubility matching technique relies on δ-values calculated by the Hildebrand and Scott equation. The proposed technique can also be applied to optimize the extraction conditions of other biomass materials.

Controlled released dynamics of methotrexate from chitosan-based capsules: A detailed energy landscape analysis

Polymeric membranes are extensively used to construct vehicles for various drug delivery applications. In this study, we investigated the potential of chitosan-based membranes as a carrier for the controlled release of methotrexate (MTX), a widely used drug in cancer treatment. The chitosan (CS) chains were cross-linked with sodium tripolyphosphate (STPP) to form a rigid matrix capable of encapsulating MTX. Molecular dynamics simulations were employed to assess the performance of the CS-based membranes in releasing MTX upon exposure to water. We have calculated the potential of mean force to understand the energy landscape in the aqueous medium or ethanol-water solution. We have observed that the free energy in the ethanol-water solution reduced to ∼52.4 kcal/mol as compared to an aqueous solution. In addition, we have shown the effect of the concentration of STPP on the binding of CS with MTX. Understanding how STPP concentration affects MTX release is crucial for designing drug delivery systems. By adjusting the concentration of STPP, one can fine-tune the release profile of the drug. We have also shown the comparative study of energy requirement to release a drug molecule from the CS matrix with and without STPP molecules. The pair correlation displayed that the water molecules have a stronger interaction with the STPP molecules compared to CS chains and MTX molecules. Our findings indicate that the CS nanoparticles exhibit promising characteristics for controlled drug release, making them a potential candidate for improving the efficacy and safety of MTX therapy in cancer treatment.

Crystalline LiYF4:Nd3+ nanoparticles synthesized via laser ablation method in water solutions of ethanol

Crystalline LiYF4:Nd3+ nanoparticles synthesized via laser ablation method in water solutions of ethanol

Characterizing the concentration of ethanol-water solutions by oblique-incidence reflectivity difference combined with deep learning algorithms

The detection of ethanol–water solution concentration plays an important role in industries, medical care, food and other aspects, which has attracted much attention. In this paper, a 632.8 nm laser combined with the oblique-incidence reflectivity difference (OIRD) method was used to obtain a signal linearly related to the solution concentration and containing the information of the dielectric constant of the solution. Combined with a variety of deep learning algorithms, ethanol–water solutions with a volume concentration of 0–95 % are detected. Among them, the prediction accuracy of the MLP, CNN, LSTM, CNN + BiLSTM + Attention models were 93.65 %, 96.54 %, 97.12 %, 99.23 %, respectively. The experimental results indicate that the OIRD method can achieve rapid, non-destructive, accurate and reliable detection of ethanol–water solutions.

Synthesis of PVA–MWCNTs–UMCNOs–starch crosslinked nanocomposite biodegradable films for the removal of methylene blue and Congo red dyes from wastewater

AbstractPlastic waste and wastewater are indeed significant environmental issues that have wide‐ranging impacts on ecosystems, human health, and the economy. This study outlines the synthesis of biodegradable polyvinyl alcohol (PVA)–starch polymeric films incorporating multiwalled carbon nanotubes (MWCNTs) derived from plastic waste and unzipped carbon nanotubes oxides (UMCNOs) as co‐filled nanomaterials. These films were formulated based on data generated using a mixture design method in Design Expert 13 software, resulting in the synthesis of 19 films utilizing five types of PVA–starch polymer solutions (Types A–E). The synthesized films underwent characterization to study their surface morphology via scanning electron microscope and Fourier transform infrared spectroscopy analysis. Subsequently, the films were individually subjected to vacuum filtration, through which cationic dyes such as methylene blue (MB) and anionic dye Congo red (CR) were passed in batches. The highest removal efficiency of 96.43% for MB dye was achieved, accompanied by an exceptionally high flux of 3146.78 LMH. Similarly, the maximum removal of 88.08% for CR was observed with a flux of 1512.66 LMH. The renewable active sites mechanism resulted in increased dye removal with every cycle. Results indicated efficient reusability, particularly when washed with ethanol–water solution.

Experimental and theoretical investigations of the threshold actuation voltages of aqueous solutions, glycerol–water solutions, and ethanol–water solutions on a coplanar electrode device

In digital microfluidics, actuation voltage is critical in droplet manipulation using electrowetting-on-dielectric. Compared to parallel electrode devices, the droplet manipulation on coplanar electrodes requires a higher actuation voltage due to its structure. This study derives an equation related to the threshold actuation voltage and many critical parameters (applied frequency, surface tension, fluid conductivity, droplet volume, dielectric thickness, etc.). Our developed model has three innovations: (1) liquid and device parameters related to the threshold actuation voltage are integrated into the model, (2) the absolute value of the complex permittivity of the fluid is added into our model to clarify the conductivity-dependent and frequency-dependent threshold actuation voltage, and (3) the extrand model is used to derive the effects of the surface tension, contact angles, and droplet radius on the threshold actuation voltage. Additionally, we used many solutions for biochemical and biomedical assays—DI (Deionized) water, DMEM (Dulbecco's Modified Eagle Medium), PBS (phosphate buffered saline), glycerol–water solutions, ethanol–water solutions, potassium chloride solutions, and sodium chloride solutions—to verify the developed Vth in our model. By using the model and conducting an experiment, we investigated the Vth of different liquids on coplanar electrodes. Our model can successfully explain the difference of Vth between these solutions on coplanar electrode devices. The model and experimental data can be utilized to predict the actuation voltage for a broad range of buffers and organic solvents on coplanar electrodes.

High-Sensitivity Differential Sensor for Characterizing Complex Permittivity of Liquids Based on LC Resonators.

This paper proposes a high-sensitivity microstrip differential sensor for measuring the complex permittivity of liquids. The prototype of the differential sensor was formed by cascading two LC resonators on a microstrip transmission line based on stepped impedance. A strong electric field was found to be distributed in the circular patch of the LC resonator; therefore, a cylindrical micropore was set in the center of the circular LC resonator to measure the dielectric sample, which maximized the disturbance of the dielectric sample on the sensor. By optimizing the size of the circular LC resonator, a high-sensitivity sensor circuit was designed and manufactured. The complex permittivity of the test sample was calculated by measuring the transmission coefficient of different molar concentrations of ethanol-water solutions. The experimental results show that the designed differential sensor can accurately measure the complex permittivity of liquid materials with an average sensitivity of 0.76%.

Exploring protective potential of Vitamin E in mitigating liver steatosis in alcoholic liver injury.

Objective: To investigate and assess the efficacy of Vitamin E in preventing or reducing fatty liver changes associated with alcoholic liver injury. Study Design: Experimental study. Setting: Department of Anatomy and Animal Facility of Peshawar Medical College, Peshawar. Period: February 2018 to April 2020. Methods: The study involved eighteen male domestic rabbits (Oryctolagus cuniculus), organizing them into categories based on the time frames specified for the research. Animals in "Category E8" were subjected to an 8-week time period, while those in "Category E4" underwent a 4-week experimental duration. Each category was further divided into three groups: "Control Group A" received standard laboratory food and daily access to normal saline as drinking water, "Experimental Group B" received standard nutrition, a 30% ethanol solution in distal water (30ml per kg/day) and normal saline for drinking, and "Experimental Group C" was treated with the necessary standard diet, a 30% ethanol solution in distal water (30ml per kg/day), and "Vitamin E" (50mg dissolved in 2ml distal water per kg/day) via nasogastric tube. Liver tissue specimens from all animals were stained with H&amp;E and Masson’s trichrome stain for quantification of fatty change. Results: A significant difference in steatosis development was observed among the E4 groups and among the E8 groups having a respective p-values of 0.001 and 0.003. This underscored the impact of alcohol within the context of alcohol-induced liver injury. However, no appreciable differences were noted between BI &amp; CI and BII &amp; CII (p-values &gt; 0.05) indicating no significant distinction in liver steatosis between subjects treated with vitamin E and those not receiving vitamin E. Conclusion: In the context of alcohol-induced liver injury, the study failed to deliver anticipated protective benefits of vitamin E. There is a possibility of adverse effects, potentially rendering its use counterproductive.

The First In Vivo Study Shows That Gyrophoric Acid Changes Behavior of Healthy Laboratory Rats.

Gyrophoric acid (GA), a lichen secondary metabolite, has attracted more attention during the last years because of its potential biological effects. Until now, its effect in vivo has not yet been demonstrated. The aim of our study was to evaluate the basic physicochemical and pharmacokinetic properties of GA, which are directly associated with its biological activities. The stability of the GA in various pH was assessed by conducting repeated UV-VIS spectral measurements. Microsomal stability in rat liver microsomes was performed using Ultra-Performance LC/MS. Binding to human serum albumin (HSA) was assessed using synchronous fluorescence spectra, and molecular docking analysis was used to reveal the binding site of GA to HSA. In the in vivo experiment, 24 Sprague-Dawley rats (Velaz, Únetice, Czech Republic) were used. The animals were divided as follows. The first group (n = 6) included healthy males as control intact rats (♂INT), and the second group (n = 6) included healthy females as controls (♀INT). Groups three and four (♂GA/n = 6 and ♀GA/n = 6) consisted of animals with daily administered GA (10 mg/kg body weight) in an ethanol-water solution per os for a one-month period. We found that GA remained stable under various pH and temperature conditions. It bonded to human serum albumin with the binding constant 1.788 × 106 dm3mol-1 to reach the target tissue via this mechanism. In vivo, GA did not influence body mass gain, food, or fluid intake during the experiment. No liver toxicity was observed. However, GA increased the rearing frequency in behavioral tests (p < 0.01) and center crossings in the elevated plus-maze (p < 0.01 and p < 0.001, respectively). In addition, the time spent in the open arm was prolonged (p < 0.01 and p < 0.001, respectively). Notably, GA was able to pass through the blood-brain barrier, indicating its ability to permeate into the brain and to stimulate neurogenesis in the hilus and subgranular zone of the hippocampus. These observations highlight the potential role of GA in influencing brain function and neurogenesis.

Synthesis and Characterization of Ni based Metal Organic Framework for Enhancing the Removal of Typical Organic Dyes

In this report we present a simple synthesis of a nickel-based metal organic framework (MOF-Ni) at the room temperature using a solution of dimethylformamide (DMF), ethanol and distilled water. The MOF-Ni synthesized in various solvents displayed numerous different properties and advantages over other materials including easy synthesis procedure, good crystallinity, rigidity, and robust chemical stability. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and thermal gravimetric analysis (TGA) were employed to analyze the as-synthesized MOF-Ni. The as-obtained MOF-Ni was used to investigate its adsorption kinetics of red telon dye (RTL) molecules. The effects of time (30–270 min), initial RTL concentration (20–300 mg/L), adsorbent dose (2–50 mg), solution pH (2–12), and temperature (10–80 °C) were investigated. The pseudo-first order rate equation was able to provide the best description of the adsorption kinetics data in the studied time scale. The Langmuir and Freundlich adsorption models were applied to describe the equilibrium isotherms, and the isotherm constants were also determined. Dye adsorption turned out to strongly depend on pH, and a low pH was found to increase the amount of adsorbed dyestuff. Compared with other samples, MOF-Ni synthesized in (DMF ​+ ​C2H5OH ​+ ​H2O) had a significantly enhanced adsorption ability for RTL dye. The MOF-Ni high adsorption capacity for RTL dye was attributed to the electrostatic attraction/repulsion phenomena. Moreover, MOF-Ni showed an improved stability at 370, 417, and 423 °C temperatures. The results obtained through our experiments suggested that our porous MOF-Ni microstructures synthesized in DMF ​+ ​C2H5OH ​+ ​H2O have potential applications for treating wastewaters containing RTL dyes.

Preparation and Regulation of Natural Amphiphilic Zein Nanoparticles by Microfluidic Technology.

Microfluidic technology, as a continuous and mass preparation method of nanoparticles, has attracted much attention in recent years. In this study, zein nanoparticles (ZNPs) were continuously fabricated in a highly controlled manner by combining a microfluidics platform with the antisolvent method. The impact of ethanol content (60~95%, v/v) and flow rates of inner and outer phases in the microfluidics platform on particle properties were examined. Among all ZNPS, 90%-ZNPs have the highest solubility (32.83%) and the lowest hydrophobicity (90.43), which is the reverse point of the hydrophobicity of ZNPs. Moreover, when the inner phase flow rate was 1.5 mL/h, the particle size decreased significantly from 182.81 nm to 133.13 nm as the outer phase flow rate increased from 10 mL/h to 50 mL/h. The results revealed that ethanol content had significant impacts on hydrophilic-hydrophobic properties of ZNPs. The flow rates of ethanol-water solutions and deionized water (solvent and antisolvent) in the microfluidics platform significantly affected the particle size of ZNPs. These findings demonstrated that the combined application of a microfluidics platform and an antisolvent method could be an effective pathway for precisely controlling the fabrication process of protein nanoparticles and modulating their physicochemical properties.

A joint experimental and theoretical investigation of the binding mechanism between zein and folic acid in an ethanol–water solution

ABSTRACT The aim of the present study was to determine the binding mechanisms between zein and folic acid in an ethanol – water solution. Fluorescence spectroscopy demonstrated that folic acid quenched the fluorescence intensity of zein by both dynamic and static fluorescence quenching mechanisms, with static quenching playing a prominent role. The binding constants (Ka) of the zein-folic acid complex at 292, 302, and 312 K were evaluated to be 5.97 × 105, 3.00 × 105 and 1.54 × 105 L/mol, respectively. The process of folic acid binding zein was driven by ∆H0 = –51.24 kJ/mol, ∆S0 = –64.90 J/mol•K. Van der Waals forces and hydrogen bonding primarily governed the formation of the zein-folic acid complex. Confirmation of the complex formation was obtained via UV-visible absorption spectroscopy, Fourier transform infrared spectroscopy, and circular dichroism spectroscopy, which also revealed alterations in the secondary structure of zein upon binding to folic acid. Measurements of particle size and zeta potential demonstrated an enhancement in the stability of the complex system. Scanning electron microscopy and transmission electron microscopy showed the complex to possess a spherical morphology, with significant changes in the zein’s morphology following its binding to folic acid. Additionally, zein increased the photostability of folic acid against UV light radiation. Molecular docking and molecular dynamics simulations were used to investigate the binding mechanisms involved further, and the results effectively elucidated the observed experimental phenomena. This research establishes a significant theoretical foundation for the utilization of zein as a system for delivering and safeguarding folic acid.

Dual-emission Tb-based coordination polymer as a ratiometric fluorescence probe for the detection of phosphate.

A simple, sensitive dual-emission probe was developed for the detection of phosphate (Pi). The probe Tb-BTB/DPA was synthesized by mixing dual-ligand, 1,3,5-tri(4-carboxyphenyl) benzene (H3BTB) and dipicolinic acid (DPA), with metal ions Tb3+ in ethanol-water solution at 40℃ for 2h. Tb-BTB/DPA exhibits two emission peaks, the emission at 362nm is attributed to H3BTB, an energy transfer between Tb3+ nodes, and DPA further enhances the fluorescence of Tb3+ at 544nm. Pi competes with ligand H3BTB to coordinate Tb3+, resulting in partial collapse of the Tb-BTB/DPA structure and interrupting the electron transfer between H3BTB and Tb3+. Therefore, the emission at 362nm is enhanced, while the emission at 544nm is unchanged, and a ratiometric fluorescence method is developed to detect Pi. Tb-BTB/DPA exhibits good linearity within the Pi concentration range (0.1-50µmol/L), and the detection limit was 25.8nmol/L. This study provides a new way to prepare probes with dual emission sensing properties.

Synthesis, Structural Characterization, and Hirschfeld Surface Analysis of a New Cu(II) Complex and Its Role in Photocatalytic CO2 Reduction.

A new Cu(II) complex, [CuL1L2(CH3COO)2(H2O)]·H2O, was synthesized by the reaction of Cu(CH3COO)2·H2O, 6-phenylpyridine-2-carboxylic acid (HL1), and 4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]pyridine (L2) in ethanol-water (v:v = 1:1) solution. The Cu(II) complex was characterized using elemental analysis, IR, UV-vis, TG-DTA, and single-crystal X-ray analysis. The fluorescence properties of the copper complex were also evaluated. The structural analysis results show that the Cu(II) complex crystallizes in the triclinic system with space group P-1. The Cu(II) ion in the complex is five-coordinated with one O atom (O2) and one N atom (N1) from one 6-phenylpyridine-2-carboxylate ligand (L1), one N atom (N2) from 4-[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]pyridine ligand (L2), one O atom (O4) from acetate, and one O atom (O5) from a coordinated water molecule, and it adopts a distorted trigonal bipyramidal geometry. Cu(II) complex molecules form a two-dimensional layer structure through intramolecular and intermolecular O-H…O hydrogen bonding. The two-dimensional layer structures further form a three-dimensional network structure by π-π stacking interactions of aromatic rings. The analysis of the Hirschfeld surface of the Cu(II) complex shows that the H…H contacts made the most significant contribution (46.6%) to the Hirschfeld surface, followed by O…H/H…O, N…H/H…N and C…H/H…C contacts with contributions of 14.2%, 13.8%, and 10.2%, respectively. In addition, the photocatalytic CO2 reduction using Cu(II) complex as a catalyst is investigated under UV-vis light irradiation. The findings reveal that the main product is CO, with a yield of 10.34 μmol/g and a selectivity of 89.4% after three hours.

Sequence-dependent dipeptide solubility in ethanol-water and DMSO-water solutions

Reliable solubility data is crucial for controlling and optimising crystallisation conditions, to provide a cost-effective purification method with the potential for scaling up. This study investigated the effect of amino acid sequence on determining peptides solubility behaviours. Four dipeptides with different sequences and combinations of alanine and glycine were selected to study their temperature dependent (283.15 K to 313.15 K) aqueous solubilities and solubility in the presence of ethanol and DMSO as antisolvent at 298.15 K. Aqueous solubility data of dipeptides presents the following order: glycyl-L-alanine (gly-ala) > L-alanyl-L-alanine (ala-ala) > glycyl glycine (gly-gly) > L-alanyl glycine (ala-gly). This solubility order has been substantiated by solvation free energy calculations using molecular dynamics (MD) simulations, providing insights into the underlying molecular interactions that govern these solubility patterns. The solubility data also demonstrated difference in the temperature dependency that: gly-gly > gly-ala > ala-gly > ala-ala, corresponding to their dissolution enthalpy order. In the presence of antisolvent range from 0 % to 80 % (by mass) concentration, peptide’s solubility was more susceptible to DMSO than ethanol. Accurate prediction of the solubilities validated the effectiveness of non-random two-liquid (NRTL) model for peptide studies.

Synthesis of polymer ionic liquids of the ionene type

New regularities have been discovered in the synthesis of polymer ionic liquids and ionene-type ionic liquids based on polyionenes derived from tetrahydro-1,4-oxazine. The methods for regulating the molecular weight of the synthesized polymers have been improved by varying the nature and composition of the solvent, as well as the concentration of the starting monomers. These improvements have resulted in the creation of new and promising materials. For the first time, we investigated the effects of temperature, solvent type and composition, chemical structure, and concentration of polyionenes derived from tetrahydro-1,4-oxazine on their behavior in water and water-ethanol solutions, as well as the shape of macromolecules in different solvents. Newly synthesized polymeric ionic liquids and ionene ionic liquids with an ionic conductivity of 10–2–10–5 S•cm–1 and a glass transition temperature range of –1500С–150С exhibit five to six orders of magnitude higher ionic conductivity compared to known analogues.

Protolytic properties of methyl yellow both in water-ethanol medium and in hardened gelatin gel with the presence of sodium dodecylsulphate and tetrabutylammonium chloride

This paper presents the results of studying the acid-base properties of the indicator dye methyl yellow in water–ethanol solutions with a volume fraction of alcohol of 10 % and 50 %. The influence of the addition of NaCl salts and tetrabutylammonium chloride, as well as the anionic surfactant sodium dodecylsulfate (SDS) on the acidity constant of the indicator, was evaluated. Under the chosen conditions, ethanol additives have a more significant effect on the pKa value. For the first time, using the dynamic light scattering method, the particle sizes, polydispersity index, and ζ-potential of colloidal particles in pure aqueous and mixed water–ethanol solutions of methyl yellow (φalcohol from 0.2 % to 50 %) in the presence of NaCl and SDS were estimated. In solutions with φalcohol = 50 % colloidal particles were not found. It has been shown that the hardened gelatin gel of photographic film can be used as a convenient sorbent for methyl yellow. In the process of dye extraction into a gelatin film from water-alcohol solutions containing SDS and NaCl, the acid-base properties of the methyl yellow remained almost unchanged. The difference between the pKa values obtained for the indicator both in solution and in the film did not exceed the measurement error.

Oxyfl uorinated polyethylene terephthalate for liquid storage containers

The effectiveness of surface modification of polyethylene terephthalate with a mixture of fluorine and oxygen to reduce the permeability to water and aqueous ethanol solutions has been studied. We obtained a decrease in the permeability coefficient of the modified fi lm for water and ethanol solutions, the degree of decrease in the permeability coefficient depends on the chemical composition of the liquid. Oxyfluorination leads to the production of a modified fi lm with an increased liquid diffusion coefficient compared to the original fi lm, which is associated with the formation of local defects which is confirmed by micrographs made with of an atomic force microscope and by measuring the surface roughness of the original and modified films.