Addressing the practical challenges of difficult drilling for blasting-induced permeability enhancement in deep, soft, and high-gas coal seams, where fractures remain underdeveloped and prone to re-compaction, this study proposes blasting operations within the floor strata. This approach aims to enhance the permeability of soft coal seams, thereby extending the duration of effective gas extraction. A bidirectional loading gas–solid coupling blasting simulation system was established in the laboratory, enabling multi-faceted analysis of experimental models through macroscopic crack patterns, internal damage mechanisms, and strain data of coal and rock masses. Comparative experiments were conducted, contrasting various control hole spacings with conventional blasting techniques. The findings reveal that as the blasting stress wave traverses the control hole walls, tensile stress waves are reflected, facilitating crack propagation. The guiding effect of the control holes and the spatial compensation they provide significantly increase the extension distance of explosion-induced cracks, resulting in directional failure of the test specimens and heightened damage in the far field of the blast. After the blasting process, the arrangement of control holes can result in an increase of up to 133% in damage to the coal seam and a reduction of up to 167% in damage to the floorboard compared to the model without control holes. Notably, when the control holes are proximal to the coal-rock interface, the near-end coal body experiences the most pronounced effects, with peak damage and tensile strain in the d = 20 mm model being 1.93 and 1.79 times higher, respectively, than those in models without control holes. Conversely, for control holes located further from the interface, the distal coal body experiences the greatest influence, exhibiting 1.53 and 1.55 times higher peak damage and tensile strain, respectively, in the d = 80 mm model compared to uncontrolled counterparts. Field observations at the C13 coal seam of a mine within the Huainan mining area corroborate these findings, where the volume of gas extraction and its concentration experienced a rapid increase following blasting and penetration enhancement. Optimum permeability enhancement occurs when the blasting hole is situated 4 m from the extraction point, resulting in a 131% increase in gas extraction purity from 0.15 × 10–3 m3/min to 1.97 × 10–3 m3/min. Furthermore, gas concentration soars by 373%, from 5.86% to 21.86%. These research outcomes offer valuable insights and hold considerable reference significance for blasting-induced permeability enhancement in deep, soft, and high gas coal seams.