Wall Envelope Research Articles

Innovate, insulate, integrate: Embracing circular economy in innovative insulations for reduced air conditioning expenses and carbon mitigation in fly ash brick buildings

Global demand for energy in the construction sector has increased drastically. A substantial portion of this energy belongs to fulfilling the heating, ventilation, and air-conditioning requirements of buildings, which are essential for maintaining the well-being of people. The development of zero-energy or environmentally friendly structures is required to attain a sustainable future. Strategic design of the building’s envelopes in green energy buildings can reduce air conditioning expenses. This article focuses on several insulation-integrated fly ash brick wall envelopes that have been designed to reduce CO2 emissions, reduce air conditioning expenses, and figure out payback times in warm-temperate and hot-arid regions. The degree-hour technique for heating and cooling, as well as unsteady heat transfer characteristics, are taken into consideration in this research. This is achieved by incorporating thirteen innovative insulation materials into fly ash bricks in three distinct configurations, (i.e., insulation layer near to the outer end of the fly ash block, on the middle of the fly ash block, and near to the inside end of the fly ash block). Experimental measurements were carried out to determine the thermo-physical characteristics of insulation materials. The analytical findings are confirmed through experimental validation. In hot-arid and composite climatic zones, placing an insulation layer (cloth-40/foam-60) near the outer end of the fly ash block resulted in the highest savings on air-conditioning costs of 0.89 $/m2 and 0.90 $/m2, respectively. They also achieved the highest carbon mitigation values at 17.2 and 16.8 kg/kWh. Insulation-integrated wall envelopes represent the pinnacle of energy efficiency in green building design, seamlessly combining advanced insulation materials with cutting-edge construction techniques to minimise energy consumption and maximise sustainability.

Building Performance Strategy to Achieve Thermal Comfort on Post-Disaster Design

Purpose: This study is a development of previous studies that focused on testing building performance from the aspect of building comfort. A house is a place to live that is used daily that must meet the needs of the occupants' thermal comfort which is greatly influenced by environmental and building conditions, such as natural lighting, air flow, and thermal performance as well as the conditions of the building's orientation layout and space openings. To determine the thermal performance of a building, it is necessary to conduct several analyses of several parameters of air temperature, air circulation and thermal conditions that occur in buildings in several conditions of building layout or orientation and openings made. Theoretical reference: Adaptive buildings are buildings that have adaptation to external environmental conditions, occupant needs and building operational conditions with the aim of increasing energy efficiency, comfort and sustainability. These adaptive buildings are able to provide a more comfortable environment, flexible and efficient space by maximizing natural ventilation and using building materials that function as insulation against temperature and solar radiation. Method: To determine the thermal comfort conditions of the building, it is necessary to conduct several tests on several parameters, such as natural lighting, air flow, and thermal performance using several analyzes such as solar analysis, air movement analysis and thermal analysis of the planned building prototype with several alternative building orientations. To test the thermal performance of the building, solar analysis and thermal analysis are carried out using Revit-based computational fluid dynamics (CFD). Results and Conclusions: The results of the study showed that the influence of building orientation and opening placement patterns will produce several different thermal performances. And the optimal results obtained from this adaptive strategy were that the optimal heat generated caused heat generation in the envelope of 0.76 kW/m2, meaning that by considering the heat transfer value of the building envelope not exceeding 35 W/m2 (SNI 6389:2020), a wall envelope made of 10 cm thick calciboard with air holes was used to withstand the rate of heat flow into the room. Research implications: As part of the adaptive building context that supports the field of knowledge and practice in the fields of architecture, engineering and the environment, it has positive implications related to the flexibility of spatial arrangement to adjust to the needs of occupants' space, the use of more efficient and environmentally friendly building technology and materials according to the needs of adaptive buildings, and the adjustment of natural ventilation strategies according to local climate potential. Originality/value: The components that distinguish this research from previous research can be seen from the various approaches and innovations carried out by the author, namely: Adaptive Design Method: developing the functionality of spatial arrangements in post-disaster residential buildings that apply the principles of spatial efficiency and arrangement to improve more dynamic relationships between spaces and their relationships with the surrounding environment. Use of New and Data-based Technology: applying new technology in ways to monitor and control the quality of space with the surrounding environment that affects it in real-time. Using technology applications for data analysis, modeling and predicting the performance of post-disaster residential buildings according to environmental and building parameters that affect them, and using big data analysis to understand the thermal behavior of buildings to optimize building design and operations.

Coassembled Multicomponent Protein Nanoparticles Elicit Enhanced Antibacterial Activity.

The waning pipeline of the useful antibacterial arsenal has necessitated the urgent development of more effective antibacterial strategies with distinct mechanisms to rival the continuing emergence of resistant pathogens, particularly Gram-negative bacteria, due to their explicit drug-impermeable, two-membrane-sandwiched cell wall envelope. Herein, we have developed multicomponent coassembled nanoparticles with strong bactericidal activity and simultaneous bacterial cell envelope targeting using a peptide coassembly strategy. Compared to the single-component self-assembled nanoparticle counterparts or cocktail mixtures of these at a similar concentration, coassembled multicomponent nanoparticles showed higher bacterial killing efficiency against Acinetobacter baumannii, Pseudomonas aeruginosa, and Escherichia coli by several orders of magnitude (about 100-1,000,000-fold increase). Comprehensive confocal and electron microscopy suggest that the superior antibacterial activity of the coassembled nanoparticles proceeds via multiple complementary mechanisms of action, including membrane destabilization, disruption, and cell wall hydrolysis, actions that were not observed with the single nanoparticle counterparts. To understand the fundamental working mechanisms behind the improved performance of coassembled nanoparticles, we utilized a "dilution effect" system where the antibacterial components are intermolecularly mixed and coassembled with a non-antibacterial protein in the nanoparticles. We suggest that coassembled nanoparticles mediate enhanced bacterial killing activity by attributes such as optimized local concentration, high avidity, cooperativity, and synergy. The nanoparticles showed no cytotoxic or hemolytic activity against tested eukaryotic cells and erythrocytes. Collectively, these findings reveal potential strategies for disrupting the impermeable barrier that Gram-negative pathogens leverage to restrict antibacterial access and may serve as a platform technology for potential nano-antibacterial design to strengthen the declining antibiotic arsenal.

Relative comparison of the benefits of wall envelope insulation materials in the South African energy zones, subject to the new national building energy efficiency standards

Introduction: South Africa is ranked among the 20 highest greenhouse gas (GHG) emitters worldwide, mainly due to its heavy reliance on coal for energy. The residential building industry can play a significant role towards the minimization of both GHG emissions and energy consumption. This research assesses the beneficial impacts of utilizing wall envelope insulation measures using five insulation materials, for a detached residential building, within the seven energy zones of South Africa in accordance with the South African National code for Building energy efficiency (SANS10400-XA).Methods: Lifecycle analysis (for 50 years), regression methods and sequential search techniques of building energy modelling were used to determine both the energy saving implications of adopting the insulation materials (at various levels of thickness), and their corresponding energy payback periods. The study area consisted of eight selected locations representing all the seven energy zones in South Africa (Welkom, Witbank, Thohoyandou, Cape Town, Pretoria, Ixopo, Sutherland, and Fraserburg).Results: Sutherland (zone 6), Cape Town (zone 4) and Fraserburg (zone 7) benefitted most from energy savings due to application of insulation measures. Witbank (Zone 2), Thohoyandou (zone 3) and Pretoria (zone 5) never benefitted from application of wall envelope insulation (in terms of energy savings). Cellulose and straw yielded the lowest payback periods. Generally, polyurethane yielded the highest net energy savings at lower insulation thickness levels, while cellulose was preferable at higher insulation thickness levels in Welkom (zone1) Cape Town (zone 4), Ixopo (zone 5H), Sutherland (zone 6) and Fraserburg (zone 7).Discussion: Lower optimal wall envelope insulation thicknesses (that maximized energy savings) appeared to correspond to locations with higher annual temperature ranges. Higher temperature ranges (hence, higher degree days) would ensure that more energy is saved in order to keep the indoor temperatures within the acceptable comfort limits, due to application of insulation. However, the selection of insulation material is also influenced by other factors such as resistance to insect and mould attack (which easily affect bio-insulation materials), fire retardancy, durability (which affects cellulose), sound proofing, structural strength, and resistance to water vapour.

Hygrothermal performance of hempcrete in a multi-layer wall envelope

Hempcrete is a promising self-bearing thermal insulation material, as it has low thermal conductivity and a minor to negative CO2 footprint. It is also believed to be applicable not only in building construction, but also for renovation or additional insulation, since hempcrete hygrothermal properties are compatible with wooden structural elements. To utilize it efficiently, it must be possible to make predictions regarding hempcrete hygrothermal performance and whether it is up to the modern standards — this requires a verified material model for use in numerical simulations. Previously, we have shown that hempcrete by itself performs well as insulation for building wall envelopes, and we have validated a material mode for hempcrete. This study assesses, both experimentally numerically, if hempcrete is suitable for use in multi-layer envelopes. A multi-layered wall envelope of a wooden multi-story building was insulated from the inside with hempcrete blocks. Relative humidity and temperature within the wall, as well as heat flow, were monitored over ∼2 years. The wall envelope was modeled numerically using WUFI. Temperature and humidity dynamics predicted numerically are in good enough agreement with experimental observations. In addition, the mold risk forecast derived from simulation and experiment results agree rather well with actual observations — no mold risk was predicted, and no mold was observed upon inspection. All of this suggests that hempcrete could indeed be used as a part of multi-layer building insulation envelopes, at least for climate conditions sufficiently similar to Latvian.

A scalable solar-based adsorption thermal battery for day and night heating in a low-carbon scenario

A proof-of-concept realization of a solar ATB wall envelope integrated into a residential building, which comprises a high-performance thermal battery and solar wall design, aiming at achieving day and night space heating in low-carbon scenarios.

Assessing Hygrothermal Performance in Building Walls Engineered for Extreme Cold Climate Environments

Buildings located in extreme cold climates encounter challenges (e.g., heat loss, condensation, and frozen utilities), especially within their wall envelopes. These challenges also play a pivotal role in occupant health, comfort, and the structural integrity of the building. While the existing literature has primarily focused on thermal performance, this study underscores the importance of evaluating hygrothermal performance within wall envelopes, given the existence of mold growth even in cases of high thermal resistance. Therefore, the aim of this study was to evaluate the hygrothermal performance of an adaptable house wall (AHW) panel that incorporates composite infill panels paired with vacuum-insulated panels to endure harsh cold conditions in Alaska. Therefore, three steps were proposed to: (1) collect the material and thermal properties of the AHW; (2) model the hygrothermal performance of the AHW in WUFI® PRO v6.7 software; and (3) analyze the results. The results revealed a moderate risk of mold growth in the inner plywood layer of the AHW, whereas the outer plywood layer showed zero risk, indicating an acceptable condition. The findings aid decisionmakers in recognizing potential mold-related issues in building walls before advancing to the construction phase.

Research into the frost resistance of cast foam plastics in multilayer wall envelopes Natalia A. Emelyanova

Research into the frost resistance of cast foam plastics in multilayer wall envelopes Natalia A. Emelyanova

Identification of potential molecular targets and repurposed drugs for tuberculosis using network-based screening approach, molecular docking, and simulation

The spread of drug-resistant strains of tuberculosis has hampered efforts to control the disease worldwide. The Mycobacterium tuberculosis cell wall envelope is dynamic, with complex features that protect it from the host immunological response. As a result, the bacterial cell wall components represent a potential target for drug discovery. Protein-protein interaction networks (PPIN) are critical for understanding disease conditions and identifying precise therapeutic targets. We used a rational theoretical approach by constructing a PPIN with the proteins involved in cell wall biosynthesis. The PPIN was constructed through the STRING database and embB was identified as a key protein by using four topological measures, betweenness, closeness, degree, and eigenvector, in the CytoNCA tool in Cytoscape. The ‘Drug repurposing’ approach was employed to find suitable inhibitors against embB. We used the Schrödinger suites for molecular docking, molecular dynamics simulation, and binding free energy calculations to validate the binding of protein with the ligand. FDA-approved drugs from the ZINC database and DrugBank were screened against embB (PDB ID: 7BVF) using high-throughput virtual screening, standard precision, and extra precision docking. The drugs were screened based on the XP docking score of the standard drug ethambutol. Accordingly, from the top five hits, azilsartan and dihydroergotamine were selected based on the binding free energy values and were further subjected to Molecular Dynamics Simulation studies for 100 ns. Our study confirms that Azilsartan and Dihydroergotamine form stable complexes with embB and can be used as potential lead molecules based on further in vitro and in vivo experimental validation. Communicated by Ramaswamy H. Sarma

Investigation of the inhibitory effect and mechanism of EGCG against Streptococcus suis sortase A.

Streptococcus suis (S. suis) seriously harms people and animals, and importantly, causes great economic losses in the pig industry. Similar to most gram-positive pathogenic bacteria, sortase A (SrtA) of S. suis can mediate the anchoring of a variety of virulence factors that contain specific sorting sequences to the surface of the bacterial cell wall envelope and participate in pathogenicity. The purpose of this study is to clarify the molecular mechanism of epigallocatechin-3-gallate (EGCG) inhibiting Streptococcus suis SrtA and provide more evidence for the development of novel anti- Streptococcus suis infections drugs. Through the SrtA substrate cleavage experiment, we found that the main component of green tea, EGCG, can effectively inhibit the enzyme activity of Streptococcus suis SrtA. Further, molecular docking and molecular dynamics simulation were used to clarify the molecular mechanism of its inhibitory effect, demonstrating that EGCG mainly interacts with amino acids at 113 and 115 to exert its inhibitory function. It was previously found that EGCG can inhibit the growth of S. suis and reduce the activity of suilysin and inhibit its expression. Our research reveals a new function of EGCG in S. suis infection. Our research proves that EGCG can effectively inhibit the transpeptidase activity of SrtA. We also clarify the accompanying molecular mechanism, providing more sufficient evidence for the use of EGCG as a potential lead compound against S. suis infection.

Moonlighting genes harbor antisense ORFs that encode potential membrane proteins

Moonlighting genes encode for single polypeptide molecules that perform multiple and often unrelated functions. These genes occur across all domains of life. Their ubiquity and functional diversity raise many questions as to their origins, evolution, and role in the cell cycle. In this study, we present a simple bioinformatics probe that allows us to rank genes by antisense translation potential, and we show that this probe enriches, reliably, for moonlighting genes across a variety of organisms. We find that moonlighting genes harbor putative antisense open reading frames (ORFs) rich in codons for non-polar amino acids. We also find that moonlighting genes tend to co-locate with genes involved in cell wall, cell membrane, or cell envelope production. On the basis of this and other findings, we offer a model in which we propose that moonlighting gene products are likely to escape the cell through gaps in the cell wall and membrane, at wall/membrane construction sites; and we propose that antisense ORFs produce “membrane-sticky” protein products, effectively binding moonlighting-gene DNA to the cell membrane in porous areas where intensive cell-wall/cell-membrane construction is underway. This leads to high potential for escape of moonlighting proteins to the cell surface. Evolutionary and other implications of these findings are discussed.

Evaluation of building energy load of a multipurpose hall and its optimization through spectrally selective fenestration and passive design concepts

Sports complexes and recreational centers are large and long-term investments that provide integrated facilities for training athletes and hosting social-cultural events. Due to their daily functioning, such buildings involve high energy consumption resulting in environmental impacts at both local and global scales. This article investigates the currently available methods for assessing the performance characteristics of a Multipurpose Hall using passive design techniques by modifying the building materials used for the wall envelope and fenestration design. Given that the proposed Multipurpose Hall is located near the composite climate of New Delhi, India, a study of climatic responses together with an energy evaluation of the building provides insight into the important envelope design for enhancing a building's energy efficiency. Several energy simulations were performed using DesignBuilder software to determine the annual lighting, heating, and cooling consumption for wall envelopes, window glazings, and dynamic shading techniques. Additionally, the solar gain of various fenestration designs was investigated, and the most energy-efficient building envelope was selected. The comparison of the baseline envelope with the modified envelope design revealed a notable improvement in energy performance.

Effects of LytR on bacterial morphology in Streptococcus pyognes

A robust cell envelope is the first line of defense in infectious pathogens when encountering host immune defenses. In Gram-positive bacteria, LytR-CpsA-Psr (LCP) family proteins play a major role in the synthesis and assembly of the cell envelope. The Gram-positive bacterium S. pyogenes causes a wide range of diseases from pharyngitis to septicemia, but the involvement of LytR in the synthesis and assembly of the cell wall envelope in this bacterium is not clear. Therefore, we investigated whether LytR of S. pyogenes, like LytR of other streptococci, is involved in cell wall formation. The lytR gene-deficient strains were used to investigate the bacteria's ability to form a chaining, drug sensitivity to penicillin G, an inhibitor of cell wall synthesis, bacterial biofilm formation, and the morphological structure of bacteria by transmission electron microscopy, and the expression of pbp2b, which encodes a penicillin-binding protein, compared with the wild-type strain. Our results showed that LytR-deficient strains had reduced bacterial chaining compared to wild-type strains. Compared to wild-type strains, LytR-deficient strains were also more drug sensitive to the cell wall synthesis inhibitor penicillin G. This genetic study was accompanied by increased expression of the pbp2b gene in the LytR-deficient strains. In addition, the LytR-deficient strain showed a reduced ability to form biofilms, and the lytR gene-deficient strain showed morphological irregularities with abnormal bacterial septa. These results indicate that the lytR gene is involved in cell wall synthesis in S. pyognes.

Research on anti leakage construction of building engineering exterior wall based on improved attribute recognition model

Due to the complexity of building shape, the diversification of building materials and the nonstandard construction technology, the seepage channel exists in the outer wall envelope of building engineering, which causes the leakage of the outer wall of the building project to become more and more serious. Therefore, the research on the construction of anti leakage of the exterior wall of the building project based on the improved attribute identification model is proposed. On the basis of the attribute recognition theory subsystem, this paper introduces the grey correlation degree method in the grey system to improve the attribute recognition theory subsystem, and uses the improved attribute recognition model to analyze the influencing factors of the leakage of the building envelope. Based on the porous medium model and numerical simulation method, this paper studies the internal flow of the medium in the external wall of construction engineering, and constructs the micro flow numerical model of fracture water. In this paper, the influence of wind pressure, height and local structure on crack flow is analyzed. The results show that the initial velocity of water is related to wind pressure, building height and the local structure of surrounding retaining structure. The water flowing into the fracture is deep at a small speed, and the velocity inside the fracture has nothing to do with the pressure distribution inside the fracture.

Innovative seismic and energy retrofitting of wall envelopes using prefabricated textile-reinforced concrete panels with an embedded capillary tube system

This paper investigates the experimental seismic performance of an innovative seismic-plus-energy retrofit solution for RC and URM structures. The intervention aims to simultaneously improve thermal efficiency and seismic safety of buildings with a light, cost-effective, and sustainable approach. The proposed hybrid retrofit system consists of prefabricated textile capillary-tube panels, mechanically connected through mortar or adhesives to existing building envelopes. This study assesses for the first time the seismic behaviour of such a system through quasi-static in-plane cyclic tests on three 3/5-scaled masonry-infilled RC frames. First, the response of a frame retrofitted with textile capillary-tube elements is compared with its two counterparts: a non-retrofitted frame and a frame retrofitted with textile-reinforced mortar and extruded polystyrene boards. Next, the paper demonstrates the application of the panels on three squat URM piers and presents preliminary but promising results from in-plane cyclic shear-compression tests. Overall, the retrofitted specimens exhibited considerably greater stiffness, strength, and displacement capacity than bare configurations. Furthermore, the panels proved to be equally effective in improving overall seismic response and controlling damage with established retrofit techniques based on textile-reinforced mortars. Finally, the thermal performance of the proposed integrated retrofitting system was assessed through in-situ experimentation on a real residential masonry building wall, exhibiting high efficiency.

High-Efficiency Plasmid DNA Transformation in Yeast.

Transformation of DNA into cells of the budding yeast Saccharomyces cerevisiae and other industrially important yeasts is most commonly performed using chemical-based methods. Current protocols typically involve exposure of the cells to lithium ions in a solution containing the crowding agent polyethylene glycol (PEG), often in conjunction with other reagents such as dimethyl sulfoxide (DMSO) that promote destabilization of the cell wall and/or cell envelope. Recent work has demonstrated that it is possible to achieve high transformation efficiencies with early stationary phase cells, i.e., small overnight liquid cell cultures, using methods that are rapid and readily scalable for high-throughput projects. Herein, we describe carrier DNAs, chemical reagents, and cell growth media that permit transformation of yeast cells with either plasmids or linear DNA fragments with high efficiency.

Numerical calculation of lateral pressure on frozen wall envelope

Numerical calculation of lateral pressure on frozen wall envelope

1249. Metabolomic Profile of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus (hVISA) in Latin-American MRSA Isolates

BackgroundVancomycin (VAN) is a first-line therapeutic option in severe infections caused by MRSA in Latin-America (LA). Development of reduced susceptibility to VAN has been associated with multiple changes in genes encoding pathways for cell wall metabolism and envelope stress responses. Nevertheless, a detailed and coherent mechanistic model to explain the phenotype remains elusive. To gain further insights into the hVISA phenotype, we sought to explore the metabolomic profile of hVISA isolates from LA. MethodsThe undirected profile of intracellular S. aureus metabolites was analysed in four clinical isolates (two hVISA and two VSSA [Vancomycin susceptible S. aureus]) belonging to the Chilean/Cordobes clone-ST5 (the predominant hVISA lineage in LA), and two reference strains Mu3 and N315. The metabolites were obtained in mid-exponential growth phase in trypticase soy broth in five independent replicates. The metabolites were determined by reverse phase liquid chromatography and hydrophilic interaction. The metabolic profile was determined by variable importance in the projection score (VIP > 1). The differences between hVISA and VSSA were maximized by orthogonal partial least squares discriminant analysis (OPLS-DA) and the affected metabolic pathways were identified with MetaboAnalyst.ResultsAmong the differences identified in the metabolic profiles of hVISA respect to VSSA, 69 metabolites were relevant. Of these, 47 were fatty acids (including glycerol), 7 amino acids and 6 nucleosides (Table 1). These changes mainly impact the biosynthesis of amino acids derived from pyruvate since tyrosine, valine and leucine, had a reduction of 34%, 57% and 41% in hVISA compared to VSSA, respectively, which suggests alterations of the acid cycle tricarboxylic (TCA). Additionally, a reduction in purine and pyrimidine metabolism in hVISA was identified with reduction of nucleosides and dinucleotides derived from the pentose phosphate pathway.Table 1. Metabolites with higher VIP scores in the comparison of the hVISA and VSSA profile ConclusionWe were able to observe metabolic alterations in TCA, pentose phosphate pathway and purine intermediates in hVISA-ST5 isolates. Our results support that gluconeogenesis and biosynthesis of carbohydrates and nucleic acids are the main pathways involved in the reduced susceptibility to VAN as reported in VISA isolates.Disclosures Cesar A. Arias, M.D., MSc, Ph.D., FIDSA, Entasis Therapeutics (Grant/Research Support)MeMed Diagnostics (Grant/Research Support)Merk (Grant/Research Support) Lorena Diaz, PhD , Nothing to disclose

Fast modeling of lightweight glubam frame structures based on connection test information

SummaryThe main lateral load‐carrying components of lightweight glued laminated bamboo (glubam) structures are shear walls. It is essential to understand lightweight glubam shear walls' performances to assess lightweight glubam structures' overall performance. A simplified numerical model was developed to predict the nonlinear response of lightweight glubam shear walls and structures. Based on the assumption that (1) the panel‐frame connectors govern the lateral resistance of the lightweight frame shear walls due to the high in‐plane shear stiffness and strength of the sheathing panel, (2) the out‐of‐plane bulking of the sheathing panel is avoided through the frame and the connections between them, and (3) the resistance capacity of the frame is negligible, the numerical model was developed based on the connection test information. Glubam nail connection tests were conducted considering different nail types and loading directions. The corresponding simplified hysteric wall model is composed of two kinds of input parameters. First are the parameters determining the wall's envelope curve under monotonic loading conditions, which regulate the hysteresis rules. The parameters related to the envelope curve are obtained through the modeling results of the nonlinear static analysis of the shear wall, whereas those related to the hysteresis rules are estimated through the connection test information. The influences of different nails, wall sizes, and openings on the walls' behavior are evaluated based on this simplified model. Based on the numerical simulation results of shear walls, the seismic performance of a glubam house was assessed.

Thermal performance simulation of nano material modified fly ash light energy-saving wallboard in assembly building

Nowadays, China's urbanized buildings are prominent, and the building area continues to grow. The study of keeping the temperature of the building walls constant has become an indispensable key standard for building energy conservation. The purpose of this paper is to simulate and study the thermal energy performance of nanomaterial modified fly ash lightweight energy-saving model in prefabricated buildings. In this paper, in the selection of nanomaterial modified fly ash technology, the finite element simulation technology is adopted to study the thermal insulation effect of nanomaterial modified fly ash in building materials, and it also plays a guiding role in the actual work. In the experiment of improving fly ash lightweight and energy-saving wallboard with nanomaterials, we set up two groups of controlled experiments, namely modifying fly ash with traditional materials and modifying fly ash with nanomaterials. By comparing the heat preservation and heat insulation performance of modified energy-saving wall panels in prefabricated buildings. The results show that the nano-material modified fly ash foamed concrete, as 140 mm thick fabricated wall panel, has a good inhibitory effect on temperature transfer in the simulation of heat transfer. Under the condition of air-conditioning heating in winter and cooling in summer, the temperature difference between the inner surface temperature of the wall envelope (16.32 °C in winter and 23.25 °C in summer) and the indoor temperature (15 °C in winter and 23 °C in summer) is less than 3 °C. Therefore, the flyash lightweight energy-saving wallboard modified by nanomaterials can play a role in heat insulation and show good heat insulation characteristics in prefabricated buildings.