Wahidin Sudirohusodo Hospital Makassar Research Articles

Factors affecting hematological abnormality in HIV-infected patients at Dr. Wahidin Sudirohusodo Hospital Makassar, Indonesia

Factors affecting hematological abnormality in HIV-infected patients at Dr. Wahidin Sudirohusodo Hospital Makassar, Indonesia

Level of Survivin in Breast Cancer Patients Serum

Objectives: The progressivity of breast cancer is controlled by a balance between cell proliferation and apoptosis. Dysregulation of apoptotic pathways leading to disorders such as cancer, autoimmune, and immunodeficiency diseases, as well as neurodegenerative disorders. Cancer cells be resistant to apoptosis by expressing an anti-apoptotic protein i.e. Apoptosis Protein Inhibitor (IAP). Survivin is an apoptotic inhibitor protein (IAP) that selectively plays a role in cancer cells, inhibits apoptosis, promotes cell division and improves angiogenesis. Detection of survivin in the blood can serve as an ideal marker for cancer diagnosis and detection. This study aims to determine the levels of survivin in breast cancer and its role as a marker of breast cancer. Methods: A cross-sectional method was conducted in Dr. Wahidin Sudirohusodo Hospital Makassar and Hasanuddin University Academic Hospital during the period from July to August 2017. There were 72 subjects (20 control, 26 non-metastatic breast cancer and 26 metastatic breast cancer), with age range of 30-61 years. The survivin test using human survivin kit with enzyme linked immunosorbent assay method (ELISA). Results: The results showed that serum surviving level in breast cancer group was significantly higher than control group (p=0,000), also higher in the metastasis group than in non-metastatic, but statistically not significant (p=0,147). Conclusion: Survivin level serum in breast cancer patients was increase.International Journal of Human and Health Sciences Supplementary Issue 01: 2024 Page: S57

Relationship between TLR-2 level and clinical or radiological severity on patients with tuberculosis spondylitis in Dr. Wahidin Sudirohusodo hospital Makassar.

Spinal tuberculosis or TB spondylitis is one of the most common types of extra pulmonary tuberculosis, which is about 15% of all cases. It causes severe morbidity, neurological deficits, and severe deformities in the patients. The growth of Mycobacterium tuberculosis in culture specimens obtained from infected tissue is the single gold standard diagnostic test for spinal TB. Toll-like receptor (TLR) is one of the important receptors in the first-line defence system against microbes. TLR-2 and TLR-4 are known to be associated with tuberculosis infection. Based on this background, the researchers were interested in examining the relationship between TLR-2 levels and the clinical and radiological severity of TB spondylitis patients. A cross-sectional study was conducted with patients diagnosed with tuberculosis spondylitis at Dr Wahidin Sudirohusodo Makassar. Patients diagnosed with TB spondylitis confirmed by blood tests, GeneExpert, and magnetic resonance imaging without prior treatment were included. Data analysis were conducted by using descriptive analysis and one-way ANOVA for bivariate analysis. The mean value of TLR2 levels in TB spondylitis patients was 9.1 g/dL. TLR2 levels in paraesthesia were significantly higher than normal (P < .05). Similar trend were analyzed on the motor neurologic status with TLR2 levels in paraparesis were significantly higher than those in normal (P < .05). There is a significant relationship between the TLR2 levels in TB spondylitis and their impaired motor and sensory function. Spinal destruction has been shown to provide significant relationship with TLR2 value in spondylitis TB.

Profile of Nasopharyngeal Carcinoma in Dr. Wahidin Sudirohusodo Hospital Makassar 2011 – 2021

Background: Nasopharyngeal carcinoma (NPC) is Indonesia’s most common head and neck malignancy. NPC presents non-specific signs and symptoms, which lead to a late or missed diagnosis. Early detection and prevention are essential based on the NPC profile. Objective: This study aimed to assess NPC’s sociodemographic and clinical characteristics in Dr. Wahidin Sudirohusodo Hospital Makassar 2011 – 2021.

Analysis of Carcinoembryonic Antigen (CEA) markers and Lymphocyte Monocyte Ratio (LMR) in patients with colorectal cancer

Background: Colorectal cancer (CRC) is cancer of the colon or rectum and one of the leading causes of cancer-related deaths. The marker for CRC is Carcinoembryonic Antigen (CEA). Lymphocytes play a role in cytotoxic cell death, inhibition of tumor cell proliferation, and migration. Lymphocyte Monocyte Ratio (LMR) is an easy-to-use laboratory biomarker to predict clinical outcomes in patients with colon cancer. This study aims to evaluate the relationship between CEA and LMR levels with the severity of CRC. Methods: The researcher cross-sectional analyzed 53 CRC patients by taking secondary data from medical records of colorectal cancer patients, CEA, and CBC data at Dr. Wahidin Sudirohusodo Hospital Makassar. The data were grouped and then analyzed statistically. Data analysis was performed using SPSS version 25.0 for Windows Results: The number of patients with male sex was 38 people (71.7%) and 15 women (28.3%). The age group of the patients ranged from 32 to 84 years, with a mean of 58.1 ± 11.3 years. The most severe degree of CRC was moderate, 29 people (73.6%), followed by mild degree, 8 people (15.1%), and severe degree, 6 people (11.3%). There is a significant negative correlation between LMR and CEA (r=-0.357; p=0.009) Conclusion: There is a significant negative correlation between LMR and CEA. A decrease in LMR can be associated with a poor prognosis in cancer patients, whereas an increase in LMR before treatment can provide a good prognosis

Description of Parental Characteristics on the Level of Anxiety of Parents Whose Children Are Being Treated in the P ICU at Dr Wahidin Sudirohusodo Hospital Makassar

Based on the research results Helena (2008) concluded from the 11 respondents who had a good knowledge gained 7 respondents experienced mild anxiety (63.6%), 3 respondents had moderate anxiety (27.2%) and 1 respondent suffered from severe anxiety (9.1%). The purpose of this study is to know the description of characteristics of parents towards anxiety level of parents whose children were hospitalized in PICU. This was descriptive research. This study will describe the association between parents; characteristics and anxiety level. The results showed that of the 40 samples studied based on the characteristics of sex, male sex as many as 7 people (17.5%) and female sex as many as 33 people (82.5%), the characteristics of age, it was shown younger age group as many as 14 people (35.0%) and older age group as many as 26 people (65%), obtained with low education as many as 10 people (25.0%) and high education as many as 30 people (75%), all respondents work (100%) or 40 respondents. The level of parental anxiety, experiencing mild anxiety level as many as 16 people (40%), anxiety levels were as many as 14 people (35%) and severe anxiety level as many as 10 people (25%). Expected in the implementation of nursing and medical measures should still pay attention to the principle of the provision of information and education of patients about the actions to be taken in order to better understand thus enhancing individual coping and reducing parental anxiety.

Characteristics of Pregnant Women with Thyroid Disorders at Wahidin Sudirohusodo Hospital Makassar

Backgrounds: At least 2% -3% of pregnant women experience thyroid dysfunction, which affects the health of the mother and baby. There is still little research on pregnant women with thyroid disorders. Aim: Investigating the characteristics of pregnant women with thyroid disorders in Dr. Wahidin Sudirohusodo Hospital Makassar.

Correlation between Histopathologic Features and β-HCG Levels in the Event of Hydatidiform Mole

Background: Hydatidiform mole is a gestational trophoblastic disease with the highest incidence in Indonesia where the incidence is 1 in 40 pregnancies. The cause of the high incidence of Hydatidiform mole is influenced by the reproductive performance of patients such as disorders of the hypothalamic-pituitary-ovarian system which causes hyperproliferation of trophoblastic cells, hydrophic degeneration of chorionic villi, and increased levels of β-hCG. Methods: This research was involving human subjects so that was related to the issues of ethical consideration. It was done at the Anatomical Pathology Laboratory and the medical record division of the Hasanuddin University Hospital and Dr Wahidin Sudirohusodo Hospital Makassar from September - November 2019. The number of samples was 28 which used the total sampling method that fulfill the inclusion and exclusion criteria. Data analysis used chi-square. Results: There are correlation between the histopathologic features with β-hCG levels, they are hydrophic degeneration of chorionic villi with β-hCG levels (p= 0.008) and proliferation of trophoblast cell with β-hCG (p= 0.001). Conclusions: There is a correlation between the histopathologic features and β-hCG levels in the event of hydatidiform mole at Hasanuddin University Hospital and Dr. Wahidin Sudirohusodo Hospital Makassar. The higher levels of β-hCG, the histopathologic features of hydropic degeneration villi will increase and trophoblastic cells will become hyperproliferation.

The Compatibility of Chest CT Scan with RT-PCR in Suspected COVID-19 Patients

Background: Thoracic CT scan plays a role in detecting and assessing the progression of COVID-19. It can evaluate the response to the therapy given. In diagnosis, the CT scan of the chest may complement the limitations of RT-PCR. Several recent studies have discussed the importance of CT scans in COVID-19 patients with false-negative RT-PCR results. The sensitivity of chest CT scan in the diagnosis of COVID-19 is reportedly around 98%. This study aimed to determine the compatibility of CT scan of the thorax with RT-PCR in suspected COVID-19 patients. Materials and methods: This research was conducted in the Radiology Department of the Wahidin Sudirohusodo Hospital Makassar from April to December 2020 with 350 patients. The method used was a 2x2 table diagnostic test. Results: The study included 188 male patients (53.7%) and 162 female patients (46.2%). The most common age group was 46–65 years (35.4%). The most common types of lesions were GGO (163 cases), consolidation (128 cases), and fibrosis (124 cases), mostly found in the inferior lobe with a predominantly peripheral or subpleural distribution. The sensitivity of the CT scan to the PCR examination was 86%, and the specificity was 91%. Conclusions: Thoracic CT scan was a good modality in establishing the diagnosis of COVID-19. CT scan of the chest with abnormalities could confirm the diagnosis in 88% of cases based on RT-PCR examination. It excluded the diagnosis in 91% based on the RT-PCR examination. The accuracy of the thoracic CT scan was 88% with RT-PCR as the reference value.

ELECTROCARDIOGRAM PATTERN PRE AND 24 HOURS POST THERAPY IN HYPONATREMIA WITH HEART FAILURE PATIENT

Background : Hyponatremia is the most common electrolyte disturbance in hospitalized heart failure patients, with a prevalence of around 19%-25%. The relationship between hyponatremia and cardiac conduction disorders has not been demonstrated yet. When there is a decrease in extracellular Na+ levels, there is a delay in the depolarization phase. This study was conducted to observe the ECG pattern in hyponatremic patients with heart failure (particularly in the P wave, PR interval, and QRS complex) and ECG changes after 24 hours of therapy. Methode: This study used a longitudinal observational descriptive method. Patients who were included in this study were hyponatremic patients with heart failure at the Wahidin Sudirohusodo Hospital Makassar from April to September 2021. The patient's electrocardiogram data when first admitted and after 24 hours of therapy. Statistical test using McNemar and Wilcoxon Signed Rank Test, where the test results are statistically significant when the p value &lt;0.05. Result : This study included 51 subjects with a distribution of 68.6% men with an age range of 18-85 years. Pre-therapy ECG pattern showed 12 patients with prolonged P-R interval, and 4 patients with widening of the QRS complex. After 24 hours of therapy, 12 people became normonatremia and the mean P wave and P-R interval were lower than pre-therapy, while the QRS complex did not show any changes. Conclusion : The ECG pattern in hyponatremia with heart failure are prolonged P-R interval and widening of the QRS complex, but the ECG changes were not significant to Na+ levels changes.

Description of the Characteristics of Parents on the Level of Anxiety of Parents whose Children are Cared for in the PICU Room of Dr. Wahidin Sudirohusodo Hospital Makassar

Based on the research results Helena (2008) conclude from the 11 respondents who had a good knowledge gained 7 respondents experiencing mild anxiety (63.6%), 3 respondents had moderate anxiety (27.2%) and 1 respondent suffered from severe anxiety (9.1 %). The purpose of this study is to know description of characteristics of parents towards anxiety level of parents whose children were hospitalized in PICU. This was descriptive research. This study will describe association between parents; characteristics and anxiety level. The result showed that of the 40 samples studied based on the characteristics of sex, male sex as many as 7 people (17.5%) and female sex as many as 33 people (82.5%), the characteristics of age, it was shown younger age group as many as 14 people (35.0%) and older age group as many as 26 people (65%), obtained with low education as many as 10 people (25.0%) and high education as many as 30 people (75%), all respondents work (100%) or 40 respondents. The level of parental anxiety, experiencing mild anxiety level as many as 16 people (40%), anxiety levels were as many as 14 people (35%) and severe anxiety level as many as 10 people (25%). Expected in the implementation of nursing and medical measures should still pay attention to the principle of the provision of information and education of patients about the actions to be taken in order to better understand thus enhancing individual coping and reduce parental anxiety.

The Effectiveness of Progressive Muscle Relaxation (PMR) Against Anxiety in Breast Cancer Patients Undergoing Chemotherapy at Dr Wahidin Sudirohusodo Hospital Makassar

Breast cancer is a malignant disease that most commonly attacks women. One pharmacological therapy for breast cancer is chemotherapy, but this treatment can cause anxiety due to the side effects it causes. Non-pharmacological treatment is really needed, one of which is Progressive Muscle Relaxation (PMR) which can reduce anxiety. The aim of the research was to determine the effectiveness of Progressive Muscle Relaxation (PMR) on anxiety in breast cancer patients. Sampling used purposive sampling technique. The total sample was 30 respondents (15 respondents were given PMR therapy) and (15 respondents were given deep breathing). Anxiety measurement uses the State Trait Anxiety Inventory (STAI) questionnaire. The test used to correlate PMR with disease duration is the Pearson test. Differences in cancer stage and mean anxiety score independent t-test. One-way anova test chemotherapy cycle. Meanwhile, the difference between pre and post PMR and control used the paired t-test. The results of the study showed no significant values for the duration of suffering from total anxiety p = 0.476, state anxiety p = 0.424, trait anxiety p = 0.464. At stage 3 it showed significant values for total anxiety p = 0.004, state anxiety p = 0.003, trait anxiety p = 0.018, at stage 4 total anxiety p = 0.009, state anxiety p = 0.009, trait anxiety p = 0.020. The chemotherapy cycle was not significant for total anxiety p = 0.084, and state anxiety p = 0.177, while trait anxiety showed a significant value of p = 0.026. Pre and post PMR showed significant values for total anxiety, state anxiety, and trait anxiety p = 0.001. The PMR and control groups showed significant values for PMR total anxiety, state anxiety, and trait anxiety p = 0.001 and the control was significant for total anxiety p = 0.028 and state anxiety p = 0.026, while trait anxiety was not significant p = 0.100. The mean anxiety scores (mean difference) of PMR and controls showed significant values for total anxiety p = 0.042, state anxiety p = 0.027 and trait anxiety p = 0.033. Conclusion Progressive Muscle Relaxation (PMR) exercise therapy is effective in reducing anxiety in breast cancer patients undergoing chemotherapy.

Perawatan Stoma pada Bayi dengan Malformasi Anorektal Letak Tinggi tanpa Fistula di Ruang Neonatal Intensive Care Unit : Studi Kasus

Anorectal malformation without fistula is a congenital disorder that requires a colostomy. Stoma care is very important to prevent infection in neonates, with good care it is hoped that there will be no damage to the integrity of the skin area around the stoma.&#x0D; This study was to report changes in skin color around the stoma in infants with high anorectal malformations without fistulas in the Neonatal Intensive Care Unit (NICU) after stoma treatment.&#x0D; Using a case study design by describing the nursing care given to baby S with a gestational age of 38 weeks in a level III A NICU room at Dr. Wahidin Sudirohusodo Hospital Makassar. Data were collected through observation and documentation of stoma care twice at an 8-day interval. Presentation of data using narrative in explaining the results obtained from case studies&#x0D; After the stoma treatment, the skin color appears reddish, and there is no necrotic. Interventions performed on infants with colostomy are stoma care to prevent damage to skin integrity. On were the first observation before the stoma treatment, the skin color around the stoma was brownish and there was necrotic then, after the stoma treatment, the skin color appeared reddish, there was no necrotic.&#x0D; In conclusion, changes in the skin color of the area around the stoma improved after treatment, the patient's stoma appeared to change from brown and there was necrotic to reddish color and no necrotic.&#x0D;

ANALISIS PELUANG PENERAPAN APLIKASI SISTEM PELAPORAN KEGIATAN PEMELIHARAAN PERALATAN MEDIS BERBASIS ANDROID MELALUI PENDEKATAN TEORI SWOT DI RSUP dr WAHIDIN SUDIROHUSODO MAKASSAR

ABSTRACT&#x0D; The hospital is one of the institutions that has an important role in providing health services to the community. Availability of medical equipment that is complete and in good condition is one of the supports for the realization of improving the quality of electromedical services, especially in the supervision and maintenance of medical facilities that are more efficient and effective at Dr. Wahidin Sudirohusodo Hospital Makassar.The purpose of this study was to determine the readiness at RSUP dr Wahidin Sudirohusodo Makassar in the plan to implement an android-based medical equipment maintenance activity reporting system.This research is a qualitative research that aims to obtain a complete picture of a matter according to the view of the human being studied. This research was carried out at Dr Wahidin Sudirohusodo Hospital Makassar in July-August 2021. By involving 5 respondents who met the requirements in this study, namely the Director of Planning, Organization and General Affairs, Head of Facility Maintenance Agency, Head of Sub-Installation of Medical Equipment Maintenance, and Electromedical technical staff. Dr. Wahidin Sudirohusodo Hospital, Makassar. Data collection was done by open interview and observation. The entire interview process was recorded using audio recordings. Data is presented in narrative form.The results showed that based on the analysis with the SWOT theory approach, it was found that the chances of implementing an Android-based medical equipment maintenance reporting system application plan could be implemented well if the strengths and opportunities were combined into a good form of planning to be implemented in the process. The conclusion in this study is that dr Wahidin Sudirohusodo Hospital Makassar is ready to plan the implementation of an android-based medical equipment maintenance activity reporting system.It is hoped that all relevant parties will always try to minimize bad possibilities in the application of the android-based medical equipment maintenance activity reporting system.&#x0D; Keywords: Android Application, Facility Maintenance, SWOT Theory

Interleukin-6 Expression in Patients with Frailty Syndrome

Frailty is an age-related biological syndrome characterized by a decrease in physiological capacity and stress resistance as a result of a gradual decline in the body's physiological systems. Frailty syndrome is categorized into three categories: robust / fit, pre-frail, and frail. As a crucial aspect of immunosenescence, the presence of chronic "inflamm-aging" systemic inflammation characterizes aging. Proinflammatory cytokines, such as IL-6, increased in response to a rise in molecular inflammation as people got older. The goal of this study was to investigate the levels of IL-6 in older people dependent on their frailty status.&#x0D; Methods: This study used a cross-sectional design with 90 patients with frailty syndrome aged &gt;=60 years who met the research requirements at Wahidin Sudirohusodo Hospital Makassar's Geriatric Polyclinic. The Cardiovascular Health Study (CHS) scoring system is used to assess frailty syndrome. The Anova and Kruskal-Wallis tests were used in the statistical analysis, and the results were considered significant if the p-value was less than 0.05.&#x0D; Results: Males made up the majority of the participants (54.4%), while females made up the rest (45.6 percent ). The most common form of weakness is frailty (43.3 percent ). Frail people had the highest levels of interleukin-6 (31.1213.40), compared to pre-frail people (22.503.29) and robust people (18.532.04). There was a statistically significant difference. Age &gt;=70 years (27.019.02) and age 60-69 years (24.7110.94) had higher IL-6 levels. There was a statistically significant difference. Only at the age of 60-69 years did IL-6 levels change significantly between robust, pre-frail, and frail people.&#x0D; Conclusions: In subjects 60-69 years old, IL-6 levels increased in proportion to the severity of frailty. Interleukin-6 levels did not vary according to the severity of frailty status in population over the age of 70

Synovial fluid evaluation in COVID-19 patients

Background: COVID-19 can provide symptoms outside the respiratory tract and musculoskeletal symptoms. Some viruses can indeed cause arthritis, and the genetic material of these viruses can be found in a joint fluid using PCR assays. With this study, we will conduct an examination using PCR on the joint fluid of COVID-19 patients who have musculoskeletal symptoms, especially arthralgia, during the infection.&#x0D; Methods: This cross-sectional study with a descriptive explanation of synovial fluid in COVID-19 patients was performed from April 1st to July 30th, 2021, with patient data collection conducted centrally at Wahidin Sudirohusodo Hospital Makassar Synovial fluid was taken from the knee using the sterile procedure in a patient that met the inclusion criteria, such as hospitalized patients who had positive PCR swab results in the nasopharynx for less than 2 weeks and had arthralgia symptoms on April – July 2021. Other musculoskeletal symptoms (e.g., myalgia and fatigue) were noted. About 2 ml sample of synovial fluid was tested using a PCR kit (M BioCov) in the laboratory. The sample shows a positive result when there is an amplification of RDNP with a CT value below 40.&#x0D; Results: 189 patients with 21 participated, 14 subjects were male, and 7 subjects were female. Age range 18 - 72 years with arthralgia, myalgia, and fatigue symptoms. Only 2 patients had arthralgia, 13 patients had myalgia and arthralgia, 1 patient had fatigue and arthralgia, and 5 patients had all of the symptoms (arthralgia, myalgia, and fatigue). Only 1 patient had direct contact with the COVID-19 patient. PCR test for synovial fluid in all patients showed negative for COVID-19.&#x0D; Conclusion: COVID-19 infection can be manifest in the musculoskeletal system. Detection of COVID-19 virus using a specimen from knee synovial fluid in a patient with musculoskeletal symptoms (arthralgia, myalgia, fatigue) was negative.

Storytelling Therapy Effectively Reduces Anxiety in Children with Leukemia at DR Wahidin Sudirohusodo General Hospital Makassar

Background: Children with leukemia are prone to experience anxiety due to various factors. Moreover, side effects of chemotherapy such as diarrhea, nausea, and vomiting add stress to the children. Storytelling therapy can be used as one of the non-pharmacological methods to reduce anxiety in children.&#x0D; Objectives: seeing the effectiveness of storytelling therapy with audio-visual media in reducing anxiety in children with leukemia&#x0D; Methods: quantitative research with quasi-experimental: pretest-posttest without a control group. Anxiety in children is measured by Hamilton Anxiety Rating Scale (HARS) instrument. Statistical test with the Wilcoxon signed-rank test with α = 0,05&#x0D; Results: There is a decrease in anxiety levels in children with leukemia after being given story-telling therapy. Based on data analysis by the Wilcoxon test, p: 0.000 means story-telling therapy is effective in reducing anxiety in children with leukemia at RSUP DR Wahidin Sudiro Husodo Hospital Makassar&#x0D; Conclusion: Storytelling therapy with audio-visual media is effective in reducing anxiety levels in children with leukemia

Molecular Detection of VEB and OXA-23 Resistance Gene in Pseudomonas Aeruginosa Isolates at Dr. Wahidin Sudirohusodo Hospital Makassar

Pseudomonas aeruginosa is a common gram-negative pathogen in nosocomial infections in immune-compromised patients. It exhibits high rates of intrinsic resistance to many classes of antibiotics, especially beta-lactam antibiotics. Production of extended-spectrum beta-lactamase (ESBL) and genes belonging to the carbapenem-hydrolyzing class D subgroup β-lactamases (CHDL) are a problem for increasing antibiotic resistance worldwide. This study aimed to identify P. aeruginosa containing the VEB and OXA-23 genes. Eighty-five clinical isolates of P. aeruginosa from various clinical samples were identified and tested for antimicrobial susceptibility using VITEK 2 compact. VEB and OXA-23 genes were detected using the Polymerase Chain Reaction (PCR) method. The PCR results revealed that 13 (15.3%) of P. aeruginosa isolates were positive OXA-23 gene, but no isolate positive for the VEB gene in P. aeruginosa isolates. The study results demonstrated the spread of the OXA-23 gene in P. aeruginosa isolates at Dr. Wahidin Sudirohusodo Hospital Makassar.

Relationship of Gastroesophageal Flap Valve with Gastroesophageal Reflux Disease Assessed Based on GerdQ Scores and Endoscopic Images

Background: Gastroesophageal reflux disease (GERD) is a condition where reflux of stomach contents causes troublesome symptoms or complications. The gastroesophageal flap valve (GEFV) is one of the protective structures against esophageal reflux. This study aimed to determine the relationship between GEFV, measured by Gastroesophageal Reflux Disease Questionnaire (GerdQ) scores, and the endoscopic features of GERD patients.&#x0D; Method: This observational cross-sectional study was performed at Wahidin Sudirohusodo Hospital Makassar from August 2021 to October 2021. The participants were GERD patients who met the inclusion criteria. They were diagnosed using GerdQ scores and endoscopic features based on the Los Angeles criteria. The GEFV was assessed using retroflection endoscopy according to Hill’s criteria. Data analysis used SPSS version 25. The Kolmogorov–Smirnov test was used to assess data normality, along with the Chi-square test and calculation of odds ratio (OR). The results of the statistical tests were significant if p&lt;0.05.&#x0D; Results: This study included 100 GERD patients: 49 men and 51 women. They had a mean age of 40.5±12.8 years and a mean body mass index of 22.4±3.8 kg/m2. Abnormal GEFV was a risk for a GerdQ score of ≥8 compared to &lt;8 (OR 4.56; 95% CI 1.53–13.52). Both normal and abnormal GEFV in esophagitis reflux were higher than in non-erosive reflux disease (p=0.943).&#x0D; Conclusion: Abnormal GEFV was a risk factor for GERD based on a GerdQ score of 8, at 4.56 times higher than with normal GEFV. No statistically significant relationship existed between GEFV and endoscopic images.

Identifying feeding artery during preoperative embolization of juvenile nasopharyngeal angiofibroma

Treatment of choice and standard of care is surgical resection of the tumor. Nasopharyngeal angiofibromas receive an abundant blood supply mainly from the external carotid branches and partly from the internal carotid artery branches. Many patients are treated with preoperative embolization to minimize the risk of intraoperative hemorrhage and related complications . This retrospective study, we obtained analysis of the medical and imaging records of 11 patients with pathologically proven juvenile nasopharyngeal angiofibroma. Who we performed preoperative endovascular embolization between January 2019 until Desember 202 in Wahidin Sudirohusodo Hospital, Makassar, Indonesia. The procedure was carried out using a cathlab monoplane Philips. A total 11 patients (only 1 female) with juvenile nasopharynx angiofibroma underwent endovascular embolization from 2019-2021 in Wahidin Sudirohusodo Hospital Makassar. Arteriography examination in patients with angiofibroma tumors revealed that the feeding arteries originate from the internal maxillary artery, ascending pharyngeal artery, fascial artery, middle meningeal artery and branches of the internal carotid artery. Identifying the feeding artery before embolization is very important to facilitate the embolization process