Motivation: The implantation of a stent into a native coronary artery represents a bold intrusion of a totally foreign substance into the circulatory system. Although most of the clinically implanted coronary stents are uneventful in patients, many however failed due to disturbed flow caused by the stent. It is always desirable to continuously carry out research that may eventually lead to the development of an ideal stent for the future. Methods: The flow dynamics of a simple helical stent is numerically analyzed by computational fluid dynamics (CFD), (CFD-ACE+ 2004, ESI-CFD INC., USA). Based on the physiological character of coronary artery, the parameters of helical stent, pitch, roughness, leading angle, and diameter are manipulated to derive flow information of wall shear stress, pressure distribution, and vortices. Results and Conclusions: The results show that the flow is dominated by the contact geometry between the blood flow and the wall when the wall of stent is thick. Swirling flow is also observed when the helical stent is implanted into the artery with large wall effect and small screw angle. At the same stent thickness, the helical stent exhibits larger wall shear stress than mesh stent. Endothelium proliferation is thus expected to decrease.