Abstract At present, in the process of oil drilling, the drill string is an essential downhole drilling tool. It is immersed in the hole filled with drilling fluid for a long time, and it is driven by the rotation of the rotary table to drill down. In this process, the drill string will not only rotate around its axis but also may rotate around the axis of the hole and produce radial motion. It is important to study the flow law of Newtonian fluid flow induced by drill string movement, which can effectively reduce drilling accidents caused by drill string vortex and buckling, thus reducing economic losses. After research and analysis, the finite volume method, which has good applicability and obvious advantages, is used to discretize the established mathematical model, and the mathematical equation after discretization is obtained. By using MATLAB software, the flow field of Newtonian fluid induced by drill string rotation motion is analyzed, the axial velocity distribution diagram and tangential velocity distribution diagram are obtained, and the velocity flow diagram under different eccentricity conditions is drawn. It is found that secondary flow occurs only when the eccentricity reaches a certain distance requirement.