The article examines the evolution of the psychiatric clinic of Voronezh State University (VSU) from the evacuation of Dorpat University to Voronezh until the reorganization of VSU in 1930 and the creation of an independent Voronezh Medical Institute on the basis of the Faculty of Medicine. A brief analysis of the activities of the heads of the Yuryevsky (Derpsky) clinic and Voronezh universities is given.