Background. Currently, there is a problem of studying intervals represented by weakly cemented core, although such rocks can be the main reservoirs. Lack of reliable petrophysical information leads to underestimation of the main parameters of porosity and permeability, which in the future is likely to lead to incorrect estimation of hydrocarbon reserves. The relevance of the work is due to the lack of unified regulatory and methodological approaches to the research of weakly cemented core material. Objective. To develop our own methodological approach by selecting technologies and techniques, which allows to carry out primary preparation, sampling, profile measurements and petrophysical studies of weakly cemented core. Materials and methods. We used weakly cemented core from the Volga-Ural oil and gas province and conducted the research in accordance with the requirements specified in the guidelines for laboratory tests using necessary supplies. The methods considered in the article cover the time interval from the early 2000s. Results. In the course of the work, standard methods of core investigation were considered, and the possibility of their application to the samples of weakly cemented rock was evaluated. The peculiarities of sample preparation and research on weakly cemented core were also revealed. Conclusions. A methodological approach was developed that allows primary preparation, sampling, profile measurements and petrophysical studies of weakly cemented core.