The treasure room at the Collegium Maius of the Jagiellonian Museum in Cracow contains an armillary sphere dating from 1510. This scientific object of excellent French workmanship contains the Jagiellonian Globe, which looks surprisingly like the Lenox Globe, a sibling of the da Vinci Globe. The fact that the Jagiellonian Globe is mounted in an armillary sphere supports the hypothesis that the Lenox, cast from reddish copper, was most likely the central part of a lost armillary sphere. A horologist copied the cartography of the Lenox Globe. It is hypothesized that he also copied the decorative artistic design of the armillary sphere as a blueprint. Using primary data in his research, the author describes the compelling Jagiellonian instrument. He concentrates on aspects of epigraphy, toponymy, orthography, iconography, cosmography, ornamental history, visual arts, heraldry, kinematics, geometry, didactics and astronomy. The methodology used is based on analogy in the arts, stemmatics, cartographic, historiographical and comparative analysis based on the latest 3D photographic scanning technology of the Lazarus Project of the University of Rochester. Furthermore, more than 40 international experts and researchers contained in the list of acknowledgements assisted in making this research possible. The author attributes the Jagiellonian Globe to Jean Coudray, Early Modern horologist active for successive French Kings in Blois. This is substantiated by a monogram. It is a capital letter C next to a reversed half-Moon on the bottom of the Jagiellonian Globe. The author provides key evidence that this French horologist constructed the instrument between 1507 and 1510 based on a model armillary sphere. In making the Jagiellonian, Jean Coudray added the latest cartographic news in the form of a Latin phrase “America noviter reperta” thereby baptizing the name of America for the first time in Early Modern history on a three-dimensional object. Compelling arguments and chronological evidence are offered by the orthography, nomenclature, applied old French dimensions, iconography of the instrument and the unique cartography of the terrestrial globe contained at its center. The specific didactic scheme of this universal armillary sphere, in addition to the whirlpools adjacent to the orb, bear the visual signature of Leonardo da Vinci. However, the French horologist was not only influenced by stylistic Renaissance and didactical aspects used by Leonardo. He copied them. These include the mirroring of the Roman numerals and of the order of the hour band on the Equator reflecting the concaveness of the object based on a Vitruvian design. In addition, the unique design of the throne of the armillary sphere is influenced by Leonardo’s kinetics. The two scrolls of the throne contained in a newly developed design, in this case one of life-giving whirlpools, echoes the kinetic untamed energy and power of nature and of the oceans in particular. The iconography of the world sphere, the cosmic egg, in between the two scrolls means perfection, the primordial form which contains all the possibilities of all the forms as Plato’s animus mundi, the soul of the world. The anonymous large mountainous island mirroring the Regio Pathalis of Pliny and Bacon is used in the cartography of the da Vinci, Lenox and Jagiellonian Globe. Finally, the author offers evidence of a bibliographical reference to a specific astronomical clock instrument just like the Jagiellonian Armillary Sphere. This reference is listed in a contemporary French inventory of the famous Florimond Robertet, notorious client of Leonardo da Vinci, dating from 1532.