Visual Recall Research Articles

How speech in acoustically different offices influences a working person? – Experiments in two countries

Working during task-irrelevant speech influences workers. Adequate room acoustic design can reduce the negative effects in open-plan offices, but harmonized target values do not exist. Our purpose was to examine the effects of room acoustic design levels on a working person during the exposure to task-irrelevant speech. The Finnish room acoustic regulation was chosen as a reference, as it is one of the strictest worldwide. Three room acoustic conditions were examined: regulation violated (Reg-) (Speech Transmission Index, STI=0.71), regulation fulfilled (Reg0) (STI=0.37), and regulation surpassed (Reg+) (STI=0.16). To examine the generalizability of the results, asimilar experiment was performed in two countries (two languages and laboratories): Finland and Germany (FinGer study, N=98). Experience was measured with questionnaires, performance with visual and auditory serial recall tasks, and physiological stress with heart rate variability. Results did not depend on the country, suggesting that our findings could be similar also in other countries. Speech annoyance and perceived concentration difficulty differed in each condition. With other experience measures, only Reg+ improved experience compared to the two other conditions. Visual serial recall performance was more accurate and faster in Reg+ than in Reg-. Accuracy was also improved in Reg0 compared to Reg-. The physiological stress levels did not depend on the condition. Our study shows that Reg0 was better than Reg- with respect to experience and performance but experience was further improved from Reg0 to Reg+. Therefore, it is beneficial to design room acoustics better than the Finnish regulation to maximize work performance and experience.

The investigation of visuospatial memory and visual attention in children with intellectual disability and Down syndrome

Within cognitive domains, memory and attention are among the most studied processes in people with intellectual disabilities, and studies have documented difficulties or even heterogeneities in their functioning. This study investigates the differences and similarities in the development of visuospatial memory and visual attention between children with typical development and intellectual disabilities of various etiologies. The study involved 106 children: 42 with typical development, 41 with intellectual disabilities, and 23 with Down syndrome. The sex ratio was 1:1, and the mean chronological age across groups was 8.81 years. Tools used included the Visual Information Recall Scale and Scales for Sustained Visual Attention and Visual Attention Span. Findings revealed that children with typical development outperformed the others, with statistically significant differences between groups. Notably, children with intellectual disabilities and Down syndrome also showed significant differences, highlighting the cognitive heterogeneity in intellectual disabilities.

Active noise-cancelling headphones do not improve cognitive performance in office noise environment

Our purpose was to determine the influence of different use settings of on-ear ANC (active noise-cancelling) headphones on performance, experience, and physiological stress in conditions resembling an office where task irrelevant speech is present. Laboratory experiment involved 54 participants, who were exposed to five conditions: 1. No headphones, 2. Headphones without ANC operation, 3. Headphones with ANC operation, 4. Headphones with sound masking playback, 5. Headphones with ANC operation and sound masking playback. In all conditions, speech was present in the room at 52 dB LAeq. Masking was 51 dB LAeq wideband noise played from the headphones. Participants' performance was measured with visual serial recall and 3-back tasks, and physiological stress with heart rate variability. The condition did not influence performances nor physiological stress. The only effects of sound condition were observed in subjective experiences. With masking (conditions 4 and 5), the speech was less annoying than without the headphones (condition 1). Sound environment was estimated to impair performance and disturb concentration less than without the headphones only in condition 5. Therefore, using headphones together with masking and ANC function can improve experience. Using headphones with ANC function alone did not improve performance nor reduce stress level.

Visual free recall and recognition in art students and laypeople.

Artists and laypeople differ in their ability to create drawings. Previous research has shown that artists have improved memory performance during drawing; however, it is unclear whether they have better visual memory after the drawing is finished. In this paper, we focused on the question of differences in visual memory between art students and the general population in two studies. In Study 1, both groups studied a set of images and later drew them in a surprise visual recall test. In Study 2, the drawings from Study 1 were evaluated by a different set of raters based on their drawing quality and similarity to the original image to link drawing evaluations with memory performance for both groups.We found that both groups showed comparable visual recognition memory performance; however, the artist group showed increased recall memory performance. Moreover, they produced drawings that were both better quality and more similar to the original image. Individually, participants whose drawings were rated as better showed higher recognition accuracy. Results from Study 2 also have practical implications for the usage of drawing as a tool for measuring free recall - the majority of the drawings were recognizable, and raters showed a high level of consistency during their evaluation of the drawings. Taken together, we found that artists have better visual recall memory than laypeople.

Multi-source auxiliary information tourist attraction and route recommendation algorithm based on graph attention network

Abstract In the field of tourism recommendation systems, accurately recommending scenic spots and routes for users is one of the hot research directions. In order to better consider the complex interaction between user preferences and attraction features, as well as the potential connections between different information sources, this study constructed a graph attention network model using knowledge graphs for tourist attraction and route recommendations, and extracted features from visual images using visual geometry group-16. The results indicate that, in Xian, when the learning rate is 0.01, the area under the curve value is 0.916. The area under the curve of New York is 0.909, and the learning rate is 0.001. The area under the curve value of the Tokyo dataset is 0.895. When the learning rate is moderate, the model quickly stabilizes in the first 16 rounds and reaches its optimal state in 26–30 rounds. When the propagation depth is 2, the accuracy is 0.920, 0.905, and 0.895, respectively. After introducing visual features, the accuracy, recall, and F1 score improved by 10 to 15.7%. The multi-layer perceptron further increased the effect by 4–6%. These experimental data fully demonstrate the effectiveness and accuracy of the recommendation algorithm. This study provides a powerful tool for tourism recommendation systems, which helps to further improve user experience.

Eye-Tracking Analyses of a Coach's Pointing Gestures Timed With Speech: Implications for Players' Recall of Basketball Tactical Instructions.

Coaches often use pointing gestures alongside their speech to reinforce their message and emphasize important concepts during instructional communications, but the impact of simultaneous pointing gestures and speech on learners' recall remains unclear. We used eye-tracking and recalled performance to investigate the impact of a coach's variously timed pointing gestures and speech on two groups of learners' (novices and experts) visual attention and recall of tactical instructions. Participants were 96 basketball players (48 novice and 48 expert) who attempted to recall instructions about the evolution of a basketball game system under two teaching conditions: speech accompanied by gestures and speech followed by gestures. Overall, the results showed that novice players benefited more from instructional speech accompanied by gestures than from speech followed by gestures alone. This was evidenced by their greater visual attention to the diagrams, demonstrated through a higher fixation count and decreased saccadic shifts between the coach and the diagrams. Additionally, they exhibited improved recall and experienced reduced mental effort, despite having the same fixation time on the diagrams and equivalent recall time. Conversely, experts benefited more from instructional speech followed by gestures, indicating an expertise reversal effect. These results suggest that coaches and educators may improve their tactical instructions by timing the pairing of their hand gestures and speech in relation to the learner's level of expertise.

The Efficacy of a Metacognitive Training Program in Amnestic Mild Cognitive Impairment: A 6-Month Follow-Up Clinical Study.

This study was conducted in response to the increasing prevalence of Alzheimer's disease (AD) dementia and the significant risk faced by individuals with amnestic mild cognitive impairment with multiple-domain deficits (aMCI-md). Given the promising effects of MTPs, the primary aim of this study was to further explore their impact by assessing the maintenance of their benefits. Thus, 45 participants were randomly allocated in two groups: the Experimental group (n = 22), which received the metacognitive training program (MTP), and the Control group (n = 23) that received the cognitive exercises program (CEP). The training programs-the MTP and the CEP-included 10 individual sessions of a one-hour duration and took place once per week. To test the efficacy of the MTP, cognitive and metacognitive outcomes were compared between two groups-Experimental (EG) and Control (CG)-at four distinct time points: before-after-3 months-6 months after intervention. Based on this study's findings, the positive effects of the MTP were evident over a six-month period. Specifically, already three months post-training, the CG began to show a decline in training-related gains. In contrast, the EG's performance consistently improved, highlighting the superior efficacy of the MTP. Gains attributed to the MTP were detected in cognitive measures: cognitive flexibility and immediate visual recall, as well as in metacognitive measures: metacognitive control, improved metacognitive beliefs of attention, and an increased use of cognitive strategies. In conclusion, the results demonstrated the sustained effects of the MTP in cognitive and metacognitive measures over a period of six months, providing novel insight into the application and efficacy of the MTP in individuals with MCI.

Human restricted CHRFAM7A gene increases brain efficiency.

CHRFAM7A, a uniquely human fusion gene, has been associated with neuropsychiatric disorders including Alzheimer's disease, schizophrenia, anxiety, and attention deficit disorder. Understanding the physiological function of CHRFAM7A in the human brain is the first step to uncovering its role in disease. CHRFAM7A was identified as a potent modulator of intracellular calcium and an upstream regulator of Rac1 leading to actin cytoskeleton reorganization and a switch from filopodia to lamellipodia implicating a more efficient neuronal structure. We performed a neurocognitive-MRI correlation exploratory study on 46 normal human subjects to explore the effect of CHRFAM7A on human brain. Dual locus specific genotyping of CHRFAM7A was performed on genomic DNA to determine copy number (TaqMan assay) and orientation (capillary sequencing) of the CHRFAM7A alleles. As only the direct allele is expressed at the protein level and affects α7 nAChR function, direct allele carriers and non-carriers are compared for neuropsychological and MRI measures. Subjects underwent neuropsychological testing to measure motor (Timed 25-foot walk test, 9-hole peg test), cognitive processing speed (Symbol Digit Modalities Test), Learning and memory (California Verbal Learning Test immediate and delayed recall, Brief Visuospatial Memory Test-Revised immediate and delayed recall) and Beck Depression Inventory-Fast Screen, Fatigue Severity Scale. All subjects underwent MRI scanning on the same 3 T GE scanner using the same protocol. Global and tissue-specific volumes were determined using validated cross-sectional algorithms including FSL's Structural Image Evaluation, using Normalization, of Atrophy (SIENAX) and FSL's Integrated Registration and Segmentation Tool (FIRST) on lesion-inpainted images. The cognitive tests were age and years of education-adjusted using analysis of covariance (ANCOVA). Age-adjusted analysis of covariance (ANCOVA) was performed on the MRI data. CHRFAM7A direct allele carrier and non-carrier groups included 33 and 13 individuals, respectively. Demographic variables (age and years of education) were comparable. CHRFAM7A direct allele carriers demonstrated an upward shift in cognitive performance including cognitive processing speed, learning and memory, reaching statistical significance in visual immediate recall (FDR corrected p = 0.018). The shift in cognitive performance was associated with smaller whole brain volume (uncorrected p = 0.046) and lower connectivity by resting state functional MRI in the visual network (FDR corrected p = 0.027) accentuating the cognitive findings. These data suggest that direct allele carriers harbor a more efficient brain consistent with the cellular biology of actin cytoskeleton and synaptic gain of function. Further larger human studies of cognitive measures correlated with MRI and functional imaging are needed to decipher the impact of CHRFAM7A on brain function.

Cognitive performance and mortality among patients receiving autologous hematopoietic stem cell transplant

Objectives Patients undergoing autologous hematopoietic stem cell transplant (HCT) are at risk for death and remain understudied relative to those undergoing allogeneic HCT. Cognitive functioning may be a useful indicator of mortality risk. We examined cognition among patients who underwent autologous HCT and its relationship to mortality. Methods Participants (N = 51; 11 patients deceased) completed tasks of processing speed, working memory, executive-mediated learning, and visual recall using the computerized CogState battery prior to HCT, 30 days post-autologous HCT, and 100 days post-autologous HCT. Results Slower processing speed (HR = 3.00) and more errors on an executive-mediated visual learning task (HR = 2.78) prior to HCT were associated with an increased risk of death following HCT. Our sample size limited longitudinal analyses of whether cognitive change predicted survival, however descriptive cognitive data of the deceased versus living patient’s performances over time suggested different patterns of performance across groups. Conclusions Pre-HCT cognition may have utility as an indicator of mortality risk following autologous HCT. More research is needed to examine whether cognitive changes after HCT could also predict mortality.

Visual Recognition Memory of Scenes Is Driven by Categorical, Not Sensory, Visual Representations.

When we perceive a scene, our brain processes various types of visual information simultaneously, ranging from sensory features, such as line orientations and colors, to categorical features, such as objects and their arrangements. Whereas the role of sensory and categorical visual representations in predicting subsequent memory has been studied using isolated objects, their impact on memory for complex scenes remains largely unknown. To address this gap, we conducted an fMRI study in which female and male participants encoded pictures of familiar scenes (e.g., an airport picture) and later recalled them, while rating the vividness of their visual recall. Outside the scanner, participants had to distinguish each seen scene from three similar lures (e.g., three airport pictures). We modeled the sensory and categorical visual features of multiple scenes using both early and late layers of a deep convolutional neural network. Then, we applied representational similarity analysis to determine which brain regions represented stimuli in accordance with the sensory and categorical models. We found that categorical, but not sensory, representations predicted subsequent memory. In line with the previous result, only for the categorical model, the average recognition performance of each scene exhibited a positive correlation with the average visual dissimilarity between the item in question and its respective lures. These results strongly suggest that even in memory tests that ostensibly rely solely on visual cues (such as forced-choice visual recognition with similar distractors), memory decisions for scenes may be primarily influenced by categorical rather than sensory representations.

Lumbosacral Plexogram: An Aid to Reconstructive Nerve Possibilities in the Lower Extremity.

The lumbosacral plexus is the network of nerves responsible for the motor and sensory function of the pelvis and lower limb. Our observation is that the anatomy of this plexus is less familiar to surgeons than that of the brachial plexus. Damage to the lumbosacral plexus and its terminal branches may have a significant impact on locomotion, posture, and stability. We have designed a visual representation of the lumbosacral plexus to aid clinicians treating peripheral nerve disorders. The utility is illustrated with a case report in which a patient underwent nerve transfers in the lower limb to restore function. A visual representation of the lumbosacral plexus is a valuable adjunct to a clinical examination and helps make sense of clinical signs. The color-coding of each root level and the arrangement of muscles from proximal to distal helps with visual recall. A clear assessment of complex lumbosacral plexus patients is essential for diagnosis and planning. As with the case described, a sound knowledge of the "plexogram" can identify solutions for complex patients and result in significant functional improvements. We hope it helps advance the field of nerve surgery and, particularly, nerve transfers.

Hippocampal subfield volumes and memory performances: associations with stimulus modality and free recall or recognition

AbstractBackgroundAge‐related memory decline is well associated with hippocampal atrophy, although the specific role of hippocampal subfields in memory function has not been thoroughly investigated yet. In this study, we investigated the associations between hippocampal subfield volumes and free recall and recognition performances in verbal and visual memory tasks in older adults without dementia.MethodWe selected 97 right‐handed participants without dementia aged 60 to 85, 42 males, from the Translational Biomarkers in Aging and Dementia (TRIAD) cohort. From T2‐weighted MRIs with 0.7*0.7*1mm voxel size, the hippocampi were segmented five subfields: 1) DG (DG); 2) CA2 with CA3 (CA2/CA3); 3) CA1; 4) strata radiatum, lacunosum and moleculare (SRLM); and 5) subiculum by using the MAGeT‐Brain algorithm. Memory was assessed with Rey Auditory Learning test for verbal free recall (RAVLT7) and recognition (RAVLT‐R), and with Aggie Figure Learning test for visual free recall (AFLT7) and recognition (AFLT‐R). Linear models were used to test the association between hippocampal subfield volumes and memory performances with age, sex and total intracranial volume as covariates (p<0.05, corrected for false discovery rate).ResultThe volumes of bilateral CA1 and SRLM were significantly associated with RAVLT7 and RAVLT‐R. The right DG volume was significantly associated with AFLT7 and RAVLT7. AFLT7 was also associated with the volume of right CA2/CA3 while AFLT‐R was not associated with any hippocampal subfield (see Figures 1 & 2).ConclusionOur results are consistent with the view that hippocampal subfields contribute differently to memory traces: CA1 for recollection that requires contextual information; the DG for pattern separation (creating new distinct representations of each stimulus); and CA3 for pattern completion (the recollection of a stimulus from a partial memory). Contextual information is more important when recollecting known words, while distinct and efficient encoding may be especially useful for search strategies inherent to free recall. Pattern completion could be particularly useful to efficiently recollect visual abstract figures based on visual features during free recall. Overall, this shows that hippocampal subfield segmentation offers a better understanding of their distinctive roles in cognition.

Hippocampal subfield volumes and memory performances: associations with stimulus modality and free recall or recognition

AbstractBackgroundAge‐related memory decline is well associated with hippocampal atrophy, although the specific role of hippocampal subfields in memory function has not been thoroughly investigated yet. In this study, we investigated the associations between hippocampal subfield volumes and free recall and recognition performances in verbal and visual memory tasks in older adults without dementia.MethodWe selected 97 right‐handed participants without dementia aged 60 to 85, 42 males, from the Translational Biomarkers in Aging and Dementia (TRIAD) cohort. From T2‐weighted MRIs with 0.7*0.7*1mm voxel size, the hippocampi were segmented five subfields: 1) DG (DG); 2) CA2 with CA3 (CA2/CA3); 3) CA1; 4) strata radiatum, lacunosum and moleculare (SRLM); and 5) subiculum by using the MAGeT‐Brain algorithm. Memory was assessed with Rey Auditory Learning test for verbal free recall (RAVLT7) and recognition (RAVLT‐R), and with Aggie Figure Learning test for visual free recall (AFLT7) and recognition (AFLT‐R). Linear models were used to test the association between hippocampal subfield volumes and memory performances with age, sex and total intracranial volume as covariates (p<0.05, corrected for false discovery rate)ResultThe volumes of bilateral CA1 and SRLM were significantly associated with RAVLT7 and RAVLT‐R. The right DG volume was significantly associated with AFLT7 and RAVLT7. AFLT7 was also associated with the volume of right CA2/CA3 while AFLT‐R was not associated with any hippocampal subfield (see Figures 1 & 2).ConclusionOur results are consistent with the view that hippocampal subfields contribute differently to memory traces: CA1 for recollection that requires contextual information; the DG for pattern separation (creating new distinct representations of each stimulus); and CA3 for pattern completion (the recollection of a stimulus from a partial memory). Contextual information is more important when recollecting known words, while distinct and efficient encoding may be especially useful for search strategies inherent to free recall. Pattern completion could be particularly useful to efficiently recollect visual abstract figures based on visual features during free recall. Overall, this shows that hippocampal subfield segmentation offers a better understanding of their distinctive roles in cognition.

Visual Perceptions Skills and its Association with Written Mathematical Communication Skills among Learning Disabilities Students in Jordan.

The present research sought at investigating the association between visual perception skills and written mathematical communication skills among a sample of students with learning disabilities in mathematics in Jordan. This was a cross-sectional correlational study that included a sample of 90 primary-stage students who were diagnosed as having learning disabilities in mathematics. To collect data, the researchers developed two data collection tools; the visual perception skills test (50 items) and the written mathematical communication skills test (6 items). The tests were validated and ensured for reliability before implementation on the original study sample. The data gathered in this study was analyzed using the Statistical Package of Social Sciences (SPSS). The results showed that there was a significant statistical association between visual discrimination and Written mathematical communication skills test (r=0.218), visual closing test and Written mathematical communication skills test (r=0.411), shape relationship perception test and Written mathematical communication skills test (r=0.438), Visual Integration and Spatial Relationship Perception Test and Written mathematical communication skills test (r=0.614), Visual information recall test and Written mathematical communication skills test (r=0.154). The results showed that there was a significant positive association between visual perception skills and written mathematical communication skills (r=0.509). The study ended up with that there is a significant positive association between visual perception skills and written mathematical communication skills among students with learning disabilities in mathematics. The study recommends developing mathematical educational material based on the visual approach and improving these skills among students with learning disabilities to develop their written mathematical communication skills.

A Process Analysis of Rey-Osterrieth Complex Figure Test Performance Using the Boston Qualitative Scoring System in HIV-Associated Neurocognitive Disorders.

Deficits in episodic verbal memory are commonly observed in persons with HIV (PWH) disease, in whom they are characterized by dysregulation of the executive aspects of encoding and retrieval and adversely impact everyday functioning. Deficits in episodic visual memory are also apparent in PWH, but we know less about their cognitive architecture. This study used the Boston Qualitative Scoring System (BQSS) for the Rey-Osterrieth Complex Figure (ROCF) to examine visual learning and recall in 43 individuals without HIV and 141 PWH who completed a full research neuropsychological, psychiatric, and medical assessment. A mixed model covarying for education and estimated verbal IQ showed that participants with HIV-associated neurocognitive disorders (HAND) performed worse than PWH without neurocognitive disorders and HIV- participants at comparable medium-to-large effect sizes across the Copy, Immediate, and Delayed trials of the BQSS-ROCF, suggesting a primary encoding deficit. A component process analysis of the BQSS-ROCF Copy Trial revealed that participants with HAND had specific difficulties with configural accuracy, cluster accuracy, and cluster placement. Within the PWH sample, measures of motor coordination and executive functions emerged as independent predictors of BQSS-ROCF Copy Trial performance. Findings extend prior research by showing that HAND may be associated with a primary encoding deficit for complex visuomotor learning and memory tasks that is driven by a combination of visuospatial, motor, and executive difficulties.

Hippocampal subfield associations with memory depend on stimulus modality and retrieval mode.

Hippocampal atrophy is a well-known feature of age-related memory decline, and hippocampal subfields may contribute differently to this decline. In this cross-sectional study, we investigated the associations between hippocampal subfield volumes and performance in free recall and recognition memory tasks in both verbal and visual modalities in older adults without dementia. We collected MRIs from 97 (41 males) right-handed participants aged over 60. We segmented the right and left hippocampi into (i) dentate gyrus and cornu ammonis 4 (DG/CA4); (ii) CA2 and CA3 (CA2/CA3); (iii) CA1; (iv) strata radiatum, lacunosum and moleculare; and (v) subiculum. Memory was assessed with verbal free recall and recognition tasks, as well as visual free recall and recognition tasks. Amyloid-β and hippocampal tau positivity were assessed using [18F]AZD4694 and [18F]MK6240 PET tracers, respectively. The verbal free recall and verbal recognition performances were positively associated with CA1 and strata radiatum, lacunosum and moleculare volumes. The verbal free recall and visual free recall were positively correlated with the right DG/CA4. The visual free recall, but not verbal free recall, was also associated with the right CA2/CA3. The visual recognition was not significantly associated with any subfield volume. Hippocampal tau positivity, but not amyloid-β positivity, was associated with reduced DG/CA4, CA2/CA3 and strata radiatum, lacunosum and moleculare volumes. Our results suggest that memory performances are linked to specific subfields. CA1 appears to contribute to the verbal modality, irrespective of the free recall or recognition mode of retrieval. In contrast, DG/CA4 seems to be involved in the free recall mode, irrespective of verbal or visual modalities. These results are concordant with the view that DG/CA4 plays a primary role in encoding a stimulus' distinctive attributes, and that CA2/CA3 could be instrumental in recollecting a visual memory from one of its fragments. Overall, we show that hippocampal subfield segmentation can be useful for detecting early volume changes and improve our understanding of the hippocampal subfields' roles in memory.

57 Clinical Utility of Neuropsychological Evaluation in the Differential Diagnosis Between Late-Onset Primary Progressive Aphasia Semantic Variant (PPA-SV) Versus Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): A Case Report

Objective:Primary progressive aphasia semantic variant (PPA-SV) is an atypical dementia subtype on the frontotemporal dementia (FTD) spectrum. PPA-SV is clinically defined by naming and semantic deficits, with progressive language decline that generalizes to other domains over time. Typically, it presents as an early-onset dementia with TDP-43 pathology, but 33-46% of PPA-SV cases display initial onset after age 65 with potentially different clinical features. Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE), a more recently discovered neurodegenerative entity, is defined by an older age of onset, hippocampal sclerosis/atrophy, and TDP-43 pathology with a gradually progressive amnestic profile that expands to other cognitive deficits over time. The authors present a case report with overlapping features and suspected TDP-43 neuropathology ante-mortem for two reasons: first, to highlight the need for clinical criteria to formally diagnose LATE, and second, to address a gap in the literature on the possible clinical differences of late-onset PPA-SV.Participants and Methods:The authors present a case of a 78-year-old Indian bilingual man (English dominant) with 18 years of education, noncontributory medical history, and gradually progressive cognitive complaints reported over the past few years who was seen for outpatient neuropsychological evaluation. Prior workup was notable for negative amyloid PET scan, negative p-tau 217 blood test, and abnormal brain MRI revealing marked bilateral hippocampal atrophy with ex vacuo ventriculomegaly and minimal cerebrovascular disease. He scored 23/30 on prior MMSE, was diagnosed with amnestic MCI, prescribed Namenda and Exelon, and complained of minor memory and word-finding difficulties with reportedly intact IADLs and no signs of NPH.Results:Neuropsychological testing revealed a profound dysnomia (RBANS Naming raw score = 1/10), and he provided 0 words on two semantic fluency tasks but 15 words on letter fluency. Receptive vocabulary score was also impaired (PPVT-4, <1st %). Memory performance also demonstrated rapid forgetting of information (RBANS List Recall raw = 0/10, Story Recall raw = 0/12) with no benefit to recognition cues (RBANS List Recognition raw = 12/20), but slightly better visual memory recall, albeit still impaired (RBANS Figure Recall raw = 4/20). Grooved pegboard scores were significantly worse with right-hand than left-hand. Irregular word reading (NAART = 16th %ile) was significantly below expectations and thought to reflect more of a surface dyslexia rather than a cultural confounder given that he has lived in the US for over 50 years and his occupational and educational history was completed in English.Conclusions:Results support the clinical utility of neuropsychological evaluation in the differential diagnosis to support a predominant clinical syndrome of PPA-SV despite overlapping features with LATE and suspected TDP-43 pathology. This case report highlights the diagnostic issue with the lack of literature describing the typical clinical progression or suggested diagnostic criteria of LATE. These findings also indicate that late-onset PPA-SV may include greater memory deficits earlier in the course, but this may also be a clinical masquerade that is more reflective of the extent of language deficits. Further research on late-onset manifestations of PPA-SV and LATE consensus clinical guidelines is advised.

Identifying Links Between Latent Memory and Speech Recognition Factors.

The link between memory ability and speech recognition accuracy is often examined by correlating summary measures of performance across various tasks, but interpretation of such correlations critically depends on assumptions about how these measures map onto underlying factors of interest. The present work presents an alternative approach, wherein latent factor models are fit to trial-level data from multiple tasks to directly test hypotheses about the underlying structure of memory and the extent to which latent memory factors are associated with individual differences in speech recognition accuracy. Latent factor models with different numbers of factors were fit to the data and compared to one another to select the structures which best explained vocoded sentence recognition in a two-talker masker across a range of target-to-masker ratios, performance on three memory tasks, and the link between sentence recognition and memory. Young adults with normal hearing (N = 52 for the memory tasks, of which 21 participants also completed the sentence recognition task) completed three memory tasks and one sentence recognition task: reading span, auditory digit span, visual free recall of words, and recognition of 16-channel vocoded Perceptually Robust English Sentence Test Open-set sentences in the presence of a two-talker masker at target-to-masker ratios between +10 and 0 dB. Correlations between summary measures of memory task performance and sentence recognition accuracy were calculated for comparison to prior work, and latent factor models were fit to trial-level data and compared against one another to identify the number of latent factors which best explains the data. Models with one or two latent factors were fit to the sentence recognition data and models with one, two, or three latent factors were fit to the memory task data. Based on findings with these models, full models that linked one speech factor to one, two, or three memory factors were fit to the full data set. Models were compared via Expected Log pointwise Predictive Density and post hoc inspection of model parameters. Summary measures were positively correlated across memory tasks and sentence recognition. Latent factor models revealed that sentence recognition accuracy was best explained by a single factor that varied across participants. Memory task performance was best explained by two latent factors, of which one was generally associated with performance on all three tasks and the other was specific to digit span recall accuracy at lists of six digits or more. When these models were combined, the general memory factor was closely related to the sentence recognition factor, whereas the factor specific to digit span had no apparent association with sentence recognition. Comparison of latent factor models enables testing hypotheses about the underlying structure linking cognition and speech recognition. This approach showed that multiple memory tasks assess a common latent factor that is related to individual differences in sentence recognition, although performance on some tasks was associated with multiple factors. Thus, while these tasks provide some convergent assessment of common latent factors, caution is needed when interpreting what they tell us about speech recognition.

The Long-Term Transferability of Clinical Judgment Via In-Class Simulations to Nursing Practice: A Qualitative Descriptive Study

BackgroundThe transferability of clinical judgment developed through in-class simulations to clinical practice is understudied. MethodsThis qualitative descriptive study utilized semi-structured interviews to determine to what extent new-to-practice nurses transfer active learning that occurred during observation of in-class simulations during their traditional pre-licensure nursing program to their nursing practice three years later. ResultsThree major themes emerged: cue recognition through visual recall, increased confidence in decision-making, and new cognitive frameworks for nursing practice. ConclusionUsing in-class simulations may improve transferability of clinical judgment through contextualizing student learning and promoting long-term retention as learners transition to practice.

How does a history of mild traumatic brain injury alter speech understanding in complex auditory environments?

Listening in complex environments is a challenge for most observers, but particularly for those with mild traumatic brain injury (mTBI). Here, we explored the relationship between working memory (WM) and the ability to understand speech in competition, using three spoken sentences presented simultaneously via earphones using a Virtual Spatial Array. The three utterances were either presented at the same spatial location or different locations. Participants completed both an auditory/visual WM task and the competing speech task. The WM task involves auditory and visual list recall as well as the ability to recall lists from one modality while ignoring the other or while attending to both modalities. Fifty adults, some with and some without a history of mTBI, participated. Their ages ranged from 18 to 74 years and they either had normal hearing or moderate hearing loss. Results showed relationships between the WM and speech tasks consistent with previous results. Further analyses will be presented exploring the ways in which a history of mTBI influences the ability to use (1) spatial cues and (2) WM to make sense of competing speech utterances.