A generalized turbulent diffusion model has been developed which evaluates the time rate of growth of a simulated ‘cloud’ of particles released into a turbulent (i.e. diffusive) atmosphere. The general model, in the form of second-order differential equations, computes the three-dimensional size of the cloud as a function of time. Parameters which influence the cloud growth, and which are accounted for in the model equations, are: (1) length scales and velocity magnitudes of the diffusive field, (2) rate of viscous dissipation e, (3) vertical stability as characterized by the relative adiabatic lapse rate (1/T)(g/Cp+∂T/∂z), and (4) vertical shear in the mean horizontal winds\({{\partial \bar U} \mathord{\left/ {\vphantom {{\partial \bar U} {\partial z}}} \right. \kern-\nulldelimiterspace} {\partial z}}\), and\({{\partial \bar V} \mathord{\left/ {\vphantom {{\partial \bar V} {\partial z}}} \right. \kern-\nulldelimiterspace} {\partial z}}\), for a given height and of spatial extent equal to that of the diffusing cloud. Sample results for near ground level and for upper stratospheric heights are given. For the atmospheric boundary layer case, the diffusive field is microscale turbulence. In the upper stratospheric case it is considered to be a field of highly interactive and dispersive gravity waves.