Abstract. The dynamics of the ice sheets on glacial timescales are highly controlled by interactions with the solid Earth, i.e., the glacial isostatic adjustment (GIA). Particularly at marine ice sheets, competing feedback mechanisms govern the migration of the ice sheet's grounding line (GL) and hence the ice sheet stability. For this study, we developed a coupling scheme and performed a suite of coupled ice sheet–solid Earth simulations over the last two glacial cycles. To represent ice sheet dynamics we apply the Parallel Ice Sheet Model (PISM), and to represent the solid Earth response we apply the 3D VIscoelastic Lithosphere and MAntle model (VILMA), which, in addition to load deformation and rotation changes, considers the gravitationally consistent redistribution of water (the sea-level equation). We decided on an offline coupling between the two model components. By convergence of trajectories of the Antarctic Ice Sheet deglaciation we determine optimal coupling time step and spatial resolution of the GIA model and compare patterns of inferred relative sea-level change since the Last Glacial Maximum with the results from previous studies. With our coupling setup we evaluate the relevance of feedback mechanisms for the glaciation and deglaciation phases in Antarctica considering different 3D Earth structures resulting in a range of load-response timescales. For rather long timescales, in a glacial climate associated with the far-field sea-level low stand, we find GL advance up to the edge of the continental shelf mainly in West Antarctica, dominated by a self-amplifying GIA feedback, which we call the “forebulge feedback”. For the much shorter timescale of deglaciation, dominated by the marine ice sheet instability, our simulations suggest that the stabilizing sea-level feedback can significantly slow down GL retreat in the Ross sector, which is dominated by a very weak Earth structure (i.e., low mantle viscosity and thin lithosphere). This delaying effect prevents a Holocene GL retreat beyond its present-day position, which is discussed in the scientific community and supported by observational evidence at the Siple Coast and by previous model simulations. The applied coupled framework, PISM–VILMA, allows for defining restart states to run multiple sensitivity simulations from. It can be easily implemented in Earth system models (ESMs) and provides the tools to gain a better understanding of ice sheet stability on glacial timescales as well as in a warmer future climate.