Indonesia Virus Research Articles

A hybrid deep learning optimization for predicting the spread of a new emerging infectious disease

<span lang="EN-US">In this study, a novel approach geared toward predicting the estimated number of coronavirus disease (COVID-19) cases was developed. Combining long short-term memory (LSTM) neural networks with particle swarm optimization (PSO) along with grey wolf optimization (GWO) employ hybrid optimization algorithm techniques. This investigation utilizes COVID-19 original data from the Ministry of Health of Indonesia, period 2020-2021. The developed LSTM-PSO-GWO hybrid optimization algorithm can improve the performance and accuracy of predicting the spread of the COVID-19 virus in Indonesia. In initiating LSTM initial weights with weaknesses, using the hybrid optimization algorithm helps overcome these problems and improve model performance. The results of this study suggest that the LSTM-PSO-GWO model can be utilized as an effective and reliable predictive tool to gauge the COVID-19 virus’s spread in Indonesia. </span>

Partial Derivatives of Gompertz, Logistic, and Weibull Non-Linear Growth Models on Confirmed COVID-19 Cases

. The epidemiological picture of COVID-19 is still unknown, and the number of confirmed cases of COVID-19 varies every day. Researchers have studied COVID-19 a lot, and many of them have used statistical models to estimate the growth of the outbreak. Non-linear statistical models can be used to describe growth behavior, as it varies in time. The aim of this research is to analyze, compare, and find the best model from the Gompertz, Logistic, and Weibull non-linear models. Daily cumulative data on confirmed COVID-19 viruses in Indonesia for 2020-2021 will be used in this research. The results obtained by the Logistic model proved to be very effective in describing the COVID-19 epidemic curve and estimating epidemiological parameters. The Logistic Model provides the best results compared to other growth models applied by Gompertz and Weibull. The R-Square of the logistic model is 0.9990, meaning that the model is able to explain or predict 99.90% of the data and 0.10% is explained by other factors. However, this research cannot explain the turning point of the curve, because there are many factors other than the model. One of them is the nature of the virus carrier from one place to another, then the behavior of the carrier who has not fully implemented the health protocol rules.

Identification of Garlic Viruses Associated with Seed Bulbs and Consumption Bulbs from Several Locations in Indonesia

Virus infection is one of the major constraints in garlic production since the viruses are readily accumulated on vegetative propagation material (bulbs). This research aimed to detect garlic common latent virus (GCLV), shallot latent virus (SLV), onion yellow dwarf virus (OYDV), and leek yellow stripe virus (LYSV) infecting local garlic as seed bulb and imported garlic as consumption bulb. Seed bulb samples were obtained from seed breeders in several garlic growing centers in Indonesia. In contrast, consumption bulb samples were obtained from plant quarantine warehouses and three local markets in Bogor. Some bulb samples were used for morphological observations, and some were germinated in the laboratory until the leaves emerged. Leaves were collected for virus detection by RT-PCR using specific primers for GCLV, SLV, OYDV, and LYSV. Seed and consumption bulbs have differences in their morphological characteristics, especially in the type of neck hardness and the size of the bulb diameter. OYDV and LYSV infections were successfully detected in seed and consumption bulbs, while SLV was only found in consumption bulbs. Nucleotide sequence analysis showed that SLV from consumption bulbs formed one group, GCLV from seed bulbs formed one group, while OYDV and LYSV from seed and consumption bulbs were in different groups, indicating that the viruses came from different strains. Further research through high-throughput detection methods and providing virus-free planting material are needed to anticipate the spread of new strains of garlic viruses in Indonesia.

Pelatihan Pengelasan lanjutan dalam Pembuatan Tong Sampah untuk Anak Berkebutuhan Panti Karya HEPHATA HKBP Sumatera Utara

In connection with the easing of the Covid 19 virus in Indonesia, the Indonesian Christian University (UKI) Engineering PKM TEAM conducted welding training offline for children with special needs. The purpose of the Service for children at the Panti Karya is to be able to provide training in welding and making trash cans easily and effectively as life skills for the children of the HEPHATA HKBP Panti Karya Foundation in North Sumatra Participants, to be able to implement cleanliness around the Hephata HKBP Panti Karya Foundation in North Sumatra as well as children who already have the skills to make trash cans from welding training can generate incoming funds for the HKBP Hephata Panti Foundation in North Sumatra. With this dedication, we can equip the children of the Karya Orphanage with life skills in making trash cans and welding to increase their competence.

Molecular characterization of Rice ragged stunt virus and Rice grassy stunt virus on Rice in Gianyar, Bali, Indonesia

Rice stunt disease is one of the causes of rice harvest failure. It is caused by the infection of Rice ragged stunt virus (RRSV) and Rice grassy stunt virus (RGSV) infection. Information about disease severity and the molecular characteristics of stunt viruses in Indonesia is still limited. Thus, this research aimed to determine the disease severity and the genetic diversity of rice stunt viruses in Gianyar, Bali. The research method consisted of observation of incidence and disease severity in the field and virus detection by reverse transcription-polymerase chain reaction (RT-PCR) using primers specific for RRSV and RGSV. The observation of the disease incidence and severity were performed in seven districts in Gianyar Regency, Bali, namely Blahbatuh, Gianyar, Payangan, Sukawati, Tampaksiring, Tegallalang, and Ubud. Stunt disease was found in all observation sites. High stunt disease incidence (> 44%) was found in three districts: Ubud, Tampaksiring, and Payangan, while the low disease incidence rate of <10% was found in Blahbatuh and Gianyar Districts. The highest stunt disease severity occurred in Tampaksiring District (60.82%), while the lowest severity occurred in Gianyar District (18.84%). The IR-64 and Ciherang cultivars are vulnerable to rice stunt disease infection. The highest homology of RRSV and RRGV nucleotides was found with Vietnam isolates being >98% and >97%, respectively. The phylogenetic analysis showed that Indonesian isolates of RRSV and RGSV were clustered in the same group as Vietnam isolates.

PENERAPAN K-MEANS DAN K-MEDOIDS BERBASIS RFM PADA SEGMENTASI PELANGGAN DI MASA PANDEMI COVID-19

The outbreak of the CORONA virus in Indonesia in early March 2020 has created unrest, especially in the business world. The impact caused some small and medium-sized businesses to go out of business, so the right marketing strategy is needed to maintain and increase customer loyalty. The purpose of this research is to segment PT Megadaya Maju Selaras' customers based on their characteristics by comparing the RFM-based K-Means and K-Medoids algorithms as attributes in the research. The dataset used comes from the purchase transaction data of PT Megadaya Maju Selaras customers. Experiments in this study used the CRISP-DM model. The results showed that the K-Means algorithm has a smaller Davies Bouldin Index (DBI) value than K-Medoids, meaning that the K-Means method is the right method for this research. With the K-Means method, the overall data shows the optimal k in cluster 4 with a DBI value of 0.286, the data before the pandemic shows the optimal k value in cluster 2 with a DBI value of 0.299, after the pandemic shows the optimal k in cluster 5 with a DBI value of 0.278. The overall data is divided into 4 segments, namely superstar, typical customer, occational customer and dormant customer. Data before the pandemic is divided into 2 segments, namely typical customers and superstars. Meanwhile, after the pandemic is divided into 5 segments, namely typical customer, occational customer, golden customer, dormant customer and superstar. With this research, PT Megadaya Maju Selaras can provide the right service for each customer group.

Aksi Solidaritas Sosial (Studi Pada Komunitas Driver Ojek Online dan Non Komunitas di kota Palangka Raya)

<table width="614" border="1" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="409"><p>Social solidarity among online motorcycle taxi drivers is the main goal in an online motorcycle taxi driver community. This can be seen in a community of online motorcycle taxi drivers when conducting associations. However, the association has faded along with the spread of the COVID-19 virus in Indonesia. This makes the community association of online ojek drivers unscheduled and unable to conduct associations between online motorcycle taxi drivers due to the implementation of community activity restrictions (PPKM). With conditions like this, the association of online motorcycle taxi drivers in a community in palangkaraya city is hampered. This study aims to find out how solidarity occurs between online motorcycle taxi drivers in Palangka Raya city after the Covid-19 pandemic when viewed from the point of view of social solidarity theory. This research uses qualitative-descriptive methods to describe each behavior of the activities of the object under study, so as to produce accurate information, also carried out with a sociological approach. The theory used is social solidarity as formulated by Emile Durkheim. All forms of data collection and processing are carried out by means of surveys as well as the author's participation in the activities of the online motorcycle taxi driver community in the city of Palangkaraya. The results of this study show that online motorcycle taxi drivers who in fact vary in ethnicity, religion and culture play an important role as actors in developing an attitude of social solidarity as a result of disaster fundraising or disaster sesame drivers, gatherings every two weeks on certain days, regular social gatherings that are carried out once a week on Saturdays.</p><p class="Normal1"> </p></td></tr></tbody></table>

Penjatuhan Pidana Mati Terhadap Pelaku Tindak Pidana Korupsi Dimasa Pandemi Covid-19

Introduction: : Amid the conditions or circumstances of the outbreak of the corona virus disease covid 2019 (covid-19) in Indonesia, it turns out that there are still crimes of corruption committed during this pandemic. Acts of corruption that no longer look at the condition of the country in a state of health emergency. In the provisions of Article 2 paragraph (2) of the corruption law it is stated that in cases of corruption committed under certain circumstances, death penalty can be imposed so that the issue raised for analysis is whether the condition of the Covid-19 pandemic can be used as an excuse for certain circumstances according to law corruption.
 Purposes of the Research: The purpose of this study is to analyze and discuss the conditions of the Covid-19 pandemic which can be used as reasons for certain circumstances according to the corruption law. death can be applied in criminal acts of corruption during the Covid-19 pandemic.
 Methods of the Research: The research used in this paper is juridical-normative, namely identifying legal issues that develop in society, studying law applications in society, or studying positive legal provisions and legal principles and doctrines to clarify research results.
 Results of the Research: In the midst of the conditions or circumstances of the outbreak of the Covid-19 virus in Indonesia, it turns out that there are still crimes of corruption committed during this pandemic. Acts of corruption that no longer look at the condition or state of the country in non-natural disaster situations. Several corruption cases that occurred during the Covid-19 pandemic are raised in this paper. Ironically, corruption can occur in social assistance funds intended for handling Covid-19, which was carried out by former social minister Juliari Batubara with a total corruption fund of 32 billion rupiah and was sentenced to 12 years in prison by the Jakarta Corruption Court.

Analysis of the Differences in Length of Stay of Covid-19 Patients with a History of Comorbids and Without a History of Comorbids on the Impact of Hospital Financing in Central Sulawesi Province in 2023

Case is a health problem experienced throughout the world. The increasing spread of the Covid virus in Indonesia has resulted in hospitals designated by the Ministry of Health being unable to accommodate patients infected with Covid. Analysis of the differences in treatment duration for Covid-19 patients with comorbidities and without comorbidities is important to know so that the prognosis of patients with comorbidities can be predicted, so that Covid-19 patients with comorbidities can receive more optimal special health services so that the death rate due to Covid-19 can be maximally prevented. and can reduce costs for treating Covid-19 patients. The aim of this research is to analyze the difference in length of stay for Covid-19 patients with and without a history of comorbidities in Central Sulawesi Province in 2023. This research uses a cross sectional type of research . The population in this study was 9 6 samples. The sampling technique used was Accidental Sampling, data analysis used was bivariate analysis with the Mann Whitney test. The results of the study showed that the highest length of stay was for Covid patients who underwent short-term treatment with a proportion of 88.5% and those with a history of comorbidities had the most comorbidities with a proportion of 63.5%. The results of the Mann Whitnay statistical test show that there is no difference in the average frequency of length of stay for Covid-19 patients with a history of comorbidities and without comorbidities. with the value ρ Value 0.512. The advice in this research is that it is hoped that the hospital, especially the Health Promotion section, will always disseminate health education about the factors that influence the length of stay and treatment of Covid-19 patients with and without comorbidities. Covid cases accompanied by comorbidities are mostly age. Furthermore, it is necessary to provide education on Covid prevention through leaflets and Covid pocket books at Posyandu for the elderly

Portraying Indonesian English language teachers’ readiness for teaching online classes

Amidst the proliferation of the COVID-19 virus in Indonesia, educators, students, and educational institutions are still adapting to the implementation of online instructional methods. This investigation delves into the preparedness of English as a Foreign Language (EFL) teachers in conducting online classes, as well as the obstacles they encounter while doing so. The purpose of this study is to serve as a foundation for schools to develop effective strategies for administering online classes, and to equip teachers with the necessary skills to facilitate learning in the online realm. This current research employed a mixed-method design in order to gather the essential information required to address the research questions at hand. The data was collected through the utilization of an online Likert-scale questionnaire and focus group interviews. The questionnaire was utilized to evaluate teachers' preparedness across three dimensions: Technological Pedagogical Content Knowledge (TPACK), teachers' presence, and institutional support. A total of 336 EFL teachers from various high schools in Indonesia voluntarily participated in the survey, while nine participants took part in the focus group interviews. The findings of this investigation indicate that, on average, EFL teachers possess a moderate to high level of perceived preparedness across the three aforementioned dimensions. This suggests that the majority of teachers are adequately equipped to engage in distance learning. However, the present findings also shed light on the concerns expressed by teachers during the online teaching and learning process. These challenges encompass the proficiency of teachers in utilizing TPACK, the workload imposed on teachers, the psychological well-being of students, and the support provided by educational institutions. Furthermore, this exploration provides a concise overview of the intricate nature of teachers' preparedness.

Reaksi Pasar Modal Akibat Pengumuman Kasus Positif Pertama Virus Covid-19 Varian Omicron Di Indonesia

The capital market reaction to an announcement or event containing information is an important thing for investors to pay attention to. Important information for investors to know for future decision making. This research aims to determine the capital market reaction caused by the announcement of the first positive case of the Omicron variant of the Covid-19 virus in Indonesia on December 16 2021. This research uses the event study method with a 7 day research period. The research sample was taken using the Slovin technique from 80 companies that are members of the Kompas100 Index. The hypothesis test used in this research is the One Sample T-test. The results of this research show that there is no market reaction as indicated by the insignificant abnormal returns obtained around the announcement event. The results of this research indicate that the capital market in Indonesia can take the form of an informationally efficient, semi-strong market.
 Keywords: Market Capital Reaction; Abnormal Return; Omicron Virus; Efficient Market Hypothesis; Signaling Theory

Genetic Comparison of H3N2 Influenza Virus in Indonesia with WHO Recommended Strains During the Period 2004 – 2021

Influenza caused by A/H3N2 virus is one commonly found infections in tropical countries. Vaccination policy against A/H3N2 virus is already established for Northern and Southern hemisphere, however, no specified policy is established for tropical countries such as Indonesia. World Health Organization (WHO) has recommended Indonesia to use vaccine formulation designated for Northern hemisphere. Some studies, however, have shown that there were mismatches between recommended vaccine and circulating strains present in Asian countries, which might have caused regional outbreaks. This study was aimed to compare the genetic makeup of WHO recommended vaccine strain with H3N2 virus circulating in Indonesia. A total of 147 HA and 148 NA complete nucleotide sequences from Indonesian population, as well as 14 HA and 14 NA WHO-recommended nucleotide sequences, were downloaded from GISAID. These sequences were subjected to phylogenetic analysis using MEGA 11. Furthermore, antigenicity of these isolates was analyzed using Kolaskar and Tangonkar Prediction method accessible through IEDB website and Vaxijen 2.0. This study revealed that WHO-recommended vaccine strain for southern hemisphere in 2010 were compatible with Indonesian strains circulating in 2009. Furthermore, there were no recommended vaccine strain that matched strain in circulation between 2010 to 2012 and 2019. Kolaskar and Tongaonkar antigenicity prediction analysis had simulated that several mutations rendered some antigenic epitopes of HA and NA protein to be non-antigenic. These findings highlighted the importance of reliable national surveillance network of influenza to prevent regional epidemic and the development of local influenza vaccine to better accommodate Indonesian population.

Implementasi Kebijakan New Normal pada Pelaku Usaha Waterpark Transera di Kabupaten Bekasi

The purpose of this study was to conclude that the management of the waterpark Bekasi supported it completely and ignored the agnation of new normal policies, Management understands the importance of applying health protocols to businesses and individuals so that the waterpark begins implementing strict, intensive health protocols starting with all of waterpark Bekasi, as well as the transfer of tools and the resulting infrastructure of the covid-19 pandemic. Causing various policies to break the spread of the covid-19 virus in Indonesia. Efforts by governments are among those that are implemented Civility to society in order to carry out Covid-19, excluding activities in all forms of crowds, assemblies, and avoiding meetings involving many people. Such efforts are aimed at communities that can be done to break the current covid-19 pandemic chain. The provisions of infrastructure in accordance with government regulations and therefore Transera waterpark provide comfort and security to the organizers.

Data Clustering of Confirmed COVID-19 Patients Using Fuzzy C-Means

The continuous mutation of COVID-19 generates new virus variants with nearly identical symptoms, such as sneezing, runny nose, sore throat, cough, fever, loss of taste and smell, and shortness of breath. Since the emergence of this virus in Indonesia, there still needs to be more research on the symptoms caused by the different COVID-19 variants, leaving the public with minimal information that may result in inappropriate early treatment, inefficient costs, and insufficient recovery time. This study aimed to classify COVID-19 patient data into two clusters based on the severity of the symptoms experienced by patients: the confirmed cluster and the unconfirmed cluster. Using Fuzzy C-Means, patient data will be clustered into two confirmed and unconfirmed clusters of covid 19 disease as the initial step in the research phase. The results of this study are anticipated to provide information on variations in the severity of symptoms among infected patients, thereby enhancing the precision of early diagnosis and treatment. The resulting clustering model is based on data collection and processing outcomes using Python and the Fuzzy C-Means algorithm, which is based on experimentation.
 Keywords: Cluster, COVID-19, Fuzzy C-Means.

CRISPR Target-based Single-guide RNA (sgRNA) for Diagnostic Testing of Hepatitis B Virus

Background: Indonesia is the second-highest country with hepatitis B cases in the South East Asian region. Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated protein 12 (Cas12) could be developed as a diagnostic tool to detect hepatitis B infection. This study was aimed to develop a diagnostic method for hepatitis B virus by designing CRISPR target-based single-guide RNA (sgRNA).Materials and method: The preCore/Core-gene sequences of hepatitis B virus were collected from the National Center for Biotechnology Information (NCBI) website. The selected sequence was submitted to Cas Designer and CRISPOR tools to design sgRNA. The resulting sgRNA was cloned in silico into an expression vector using Benchling software.Results: The 23-nucleotide sequence 5'- GTAGTCAGTTATGTCAATGTTAA-3’ had 30% GC content, 68.3 out-of-frame and 76 predicted efficiencies. This sequence had no mismatch based on analysis.Conclusion: This preliminary study will help design a CRISPR-based diagnostic kit for the detection of hepatitis B virus in Indonesia. However, further in vitro and in vivo studies are required to demonstrate its potential and efficiency.Keywords: CRISPR-Cas12b, diagnostic, HBV, sgRNA

Detection and identification of foot-and-mouth disease O/ME-SA/Ind-2001 virus lineage, Indonesia, 2022

ABSTRACT Foot-and-mouth disease (FMD) is a contagious disease affecting cloven-hoofed animals, which has been well-documented as one of the major animal diseases that causes severe economic loss in livestock sectors. The disease is endemic in many countries, particularly in Asia and Africa. Indonesia has been declared a disease-free country since 1986, and the World Organization of Animal Health (WOAH/OIE) recognized Indonesia as an FMD-free country without vaccination in 1990. However, the FMD virus was detected in many disease outbreaks in cattle and goats in Indonesia in May 2022. This study reports the detection and identification of FMD serotype O viruses in Indonesia. Although these viruses appeared to belong to the ME-SA/Ind-2001e lineage, they formed a unique cluster with 95.3% average nucleotide sequence similarity of the FMD VP1 gene to Ind-2001e viruses from other Asia countries. The illegal trade of live animals from endemic areas in Southeast Asia is one of the possible routes regarding the incursion of FMD in Indonesia, however, it requires further investigation.

IMPROVING STUDENTS’ READING COMPREHENSION THROUGH SQ5R METHODS: A DISTANCE LEARNING DURING THE PANDEMIC COVID-19

The entry of the Covid-19 virus in Indonesia has had a major impact on the education sector. The teacher could use several strategies during the learning process to be able to achieve the learning objectives. This study aimed to optimize the use of the Survey, Question, Read, Recite, Record, Review, Reflect (SQ5R) method in teaching reading during online learning at SMPN 3 Lamongan. The researcher used action research with direct observation during the learning process. The results showed that the SQ5R method could improve students' reading comprehension. The minimum score obtained by students in the initial test was 45. This value increased up to 65 in the final test, which indicated that all students had reached the minimum passing criteria standard that had been set. Meanwhile, the observations showed that students were able to analyze visual information, predict content and improve their notes. Overall, it was evident that the SQ5R approach has a positive impact on students' reading comprehension.

DAMPAK PANDEMI TERHADAP KETAHANAN KELUARGA PEDAGANG KAKI LIMA DI KOTA PROBOLINGGO

Since the end of 2019, the world has been shocked by the outbreak of the corona virus or what we usually refer to as Covid-19 which has spread in almost all parts of the world. The spread of this epidemic has had a major impact on various sectors in the world order, from the cancelation of large-scale events (international sports matches) to the almost complete cancellation, the economic decline in several countries, including Indonesia. The spread of the Covid-19 virus in Indonesia greatly affected all sectors, especially in the economic sector. The impact of this economic downturn was also felt by street vendors in Probolinggo City, who experienced a decrease in income due to the PSBB policy. The impact of the decrease in the income of street vendors in Probolinggo City is very influential on the harmony of their families, it is not uncommon for differences of opinion to occur which result in arguments between husbands and wives. Especially with financial problems when the wife asks for shopping money to meet her daily needs, but the husband, during the pandemic, his income from sales has decreased drastically, even to the point where he is forced not to sell because the place they usually use to sell is closed.

Analysis Of Students Mastering Speaking And Listening Skill In English Course Using Interactive Learning Multimedia Method In Online Class At Stikom Uyelindo Kupang

The outbreak of the covid-19 virus in Indonesia has had major consequences for the world of education, which has issued a government policy through the ministry of education and culture regarding the prohibition of universities from holding lectures in order to break the chain of the spread of the covid-19 virus. One alternative learning method that is considered appropriate to replace face-to-face lectures with lectures held online by the campus as a facilitator of learning media providers as used on the STIKOM Uyelindo Kupang campus is by using zoom meeting media. In English courses, especially in speaking and listening classes, they have difficulty in giving lectures in online lectures. This will result in the level of mastery of students' speaking and listening skills. Therefore, the authors apply interactive multimedia learning methods using English films that are played during lectures. The purpose of this study was to analyze students' abilities in speaking and listening classes using interactive multimedia learning methods held online. The research method used is quantitative using questionnaires distributed by sampling to students related to the learning method by watching movies in English online classes. This method describes an interactive multimedia learning method held online at STIKOM Uyelindo Kupang in English courses (speaking and listening classes), with STIKOM Uyelindo Kupang students as research subjects. With the application of learning methods with interactive multimedia in speaking and listening classes in English courses, students can experience a fun learning process so that they can improve students' speaking and listening skills.
 

Edukasi Covid-19 Sebagai Adaptasi Kebiasaan Baru Pada Anak

Real Work Lecture is a student learning process through various activities directly in the community. Students strive to be part of the community and are actively and creatively involved in the dynamics that occur in society. Students have a strategic role to change the Real Work Lecture (KKN) which is a form of dedication of higher education students to the community through the provision of assistance, one of which is counseling. The existence of the COVID-19 virus in Indonesia is still one of the problems that children inside or outside of school do not understand, so our group held a Real Work Lecture (KKN) program through counseling which aims to provide education on the COVID-19 virus. 19. In the implementation method, we went directly to the field to provide direct counseling and provide an approach to students at the MI Al-Hidayah school. This counseling is held in grades 2, 3 and 4 which are divided into several classes within the whole class. The results achieved from this outreach activity were providing an understanding of covid-19, children complying with health protocols to prevent the transmission of covid-19 and children having high awareness about the dangers of covid-19.