Virtual Health Library Research Articles

Oral herpes simplex virus infection in patients undergoing chemotherapy - an integrative review.

The purpose of this study is to undertake an integrative literature review in order to determine the prevalence, etiology, and reactivation of oral HSV infection in patients receiving chemotherapy (CT). The study was carried out in the PubMed/MEDLINE, Embase, Virtual Health Library, and Scopus databases, using the descriptors "Herpes Simplex", "Viral Diseases", "Mouth", and "Antineoplastic Agents". The findings suggest that HSV infection is widespread in this group of patients and can be severe. HSV infection is frequent in CT patients, and treatment should begin as soon as it is feasible, utilizing antivirals to avoid future difficulties, as patients are immunocompromised. It is critical for health professionals to be fully informed on the dangers and treatment choices available, with the most appropriate therapy for each circumstance. Furthermore, more recent research with acceptable methodological rigor is required to better quantify the prevalence of HSV in these patients.

Cuidados de enfermagem forense aos homens adultos vítimas de violências sexuais: scoping review

Abstract Objective To map and synthetize evidence on forensic nursing care for adult men victims of sexual violence. Methods A scoping review in accordance with JBI method. The eligibility criteria included: Population - adult men aged 18 to 59 years old; Concept - forensic nursing care; and Context - sexual violence against an adult man treated in health services. The search was carried out in three stages by two researchers, with the participation of a third reviewer to solve doubts. Data collection was carried out from data sources using descriptors and keywords. For this review, the temporal and idiomatic cut-off was not updated. The Virtual Health Library (VHL), Nursing Database (BDENF), Medical Literature Analysis and Retrieval System Online (MEDLINE) via PubMed, CINAHL via Ebsco databases and gray literature were used. Data were systematically spread sheeted, and inductive content analysis was carried out on 16 included studies. Synthesis of results was presented using charts, infographics and diagrams. Results It focused on compassionate care and helping relationship, subjective data recording, need to remove the victim’s clothes, head-foot examination, injury recording on body diagrams, photographic records, forensic trace collection and preservation, oropharyngeal collection, penile, scrotal and anorectal swabs. Care related to colposcopy, use of Wood’s lamp and anoscopy was mapped. Conclusion Situations of sexual violence against men, although little addressed, can occur frequently in everyday life, which implies the recognition of care that can promote welcoming in order to preserve their integrity and reduce trauma arising from this situation as well as guaranteeing forensic trace recording.

As práticas de terapeutas ocupacionais na enfermaria pediátrica: uma revisão integrativa

Abstract Introduction The pediatric ward is a field of occupational therapy, which helps patients and their companions develop strategies to cope with illness and hospitalization. Objective To identify, in the scientific literature, the practices of occupational therapists in pediatric wards in assisting children, adolescents and accompanying family members. Method This is an Integrative Literature Review, carried out in the databases: Virtual Health Library, MEDLINE and PubMed; and manual search in Brazilian journals: Cadernos Brasileiros de Terapia Ocupacional, Revista Interinstitucional Brasileira de Terapia Ocupacional and Revista de Terapia Ocupacional da Universidade de São Paulo. The articles were exported to the Rayyan® tool and selected by two authors independently. Data processing was carried out through Content Analysis, in thematic mode, using the ATLAS.ti® software. Results 23 articles were included and the analysis resulted in four categories: “Intervention”; “Intervention resources”; “Overview of occupational therapy services”; and “Humanization in family monitoring care”. Conclusion The study presents a perspective of occupational therapy in the pediatric ward, based on selected literature, offering elements that can help professionals guide their interventions and guide new studies on the topic.

Natalizumab intake during pregnancy in women with multiple sclerosis: a meta-analysis of current evidence

Background: Disease-modified therapy has changed the previous practice of discontinuing multiple sclerosis (MS) treatment for fear of side effects that might impact pregnancy. Many studies have described the use of natalizumab as a medicinal agent during pregnancy, with mixed results regarding its safety and efficacy during pregnancy. For instance, this study aimed to investigate the pregnancy outcomes in pregnant women with MS who took natalizumab during the pregnancy period. Methods: A systematic literature search was conducted during July 2023, adhering to the PRISMA guidelines. Five databases were included: PubMed, Google Scholar, Web of Science, Virtual Health Library, and Scopus. The following keywords were employed in the search "multiple sclerosis," "pregnancy," "pregnancies, "pregnant," and "natalizumab." Results: Only eight papers out of 1,000 total records were included. No significant difference between natalizumab and the control group in terms of abortion, C-section, preterm birth, congenital abnormalities, or birth height was found (p > 0.05). However, the natalizumab-treated group had a significantly lower birth weight than the control group [Mean difference = -97.89; 95% confidence interval (CI) = -171.32, -24.45], with 82.7% relapse rate (95% CI = 72.1-89.8), being highest in the second trimester (24.9%; 95% CI = 7.4, 58.0). Conclusion: While Natalizumab treatment appears to be relatively safe in terms of abortion rates, C-section rates, preterm delivery rates, and congenital anomalies, the increased relapse rate during pregnancy and lower birth weight observed necessitate careful monitoring and individualized care for pregnant MS patients taking natalizumab.

Valvulopathies of Rheumatic Origin: Management and Complications

Objective: The objective of this study is to gather information and studies about valvular heart disease of rheumatic origin and its clinical repercussions, management and complications. Methods: Integrative review, carried out between August 2024, using the digital library Scientific Electronic Library Online (SciELO), the Virtual Health Library (VHL) and PUBMED in the databases using the Boolean operators: AND and OR. The results were obtained through management with the Rayyan 16 QCRI application and were structured in PRISMA flowcharts. Results: With the search in the databases, 219 articles were found, of which 122 were selected for reading and, according to the objective of the present work, 7 articles were included in the research. Conclusion: In the studies observed, it is concluded that rheumatic valvular disease is a high-impact condition on the quality of life of patients who suffer from them and who influence in one way or another in the development of a country, as many manifest themselves in ages at which the person is economically active and the onset and exacerbations of symptoms translate into frequent work incapacity, hospitalizations and even more so if a surgical intervention is planned. It is important that the identification of clinical patterns by health professionals, with the early diagnosis and timely treatment.

Health care for patients with long COVID: a scoping review.

To map the scientific evidence on the care offered to health service users with Long Covid-19. This is a scoping review based on the methods of the Joanna Briggs Institute. Primary studies were included, in Portuguese, English and Spanish, published between December 2019 and June 2023, in the Virtual Health Library, Web of Science, Scopus, PUBMED, SciELO and LITCovid LongCovid databases. Of the ١٣ articles analyzed, it stands out that the care provided to patients with Long Covid is associated with drug prescription, indication of physical exercises, telerehabilitation and physiotherapy. A fragmentation was identified in the care provided to users of health services with Long Covid, with care directed only at isolated symptoms, without addressing the biopsychosocial care that people with this condition need.

Inflammatory Hematological Indices, Cardiovascular Disease and Mortality: A Narrative Review.

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, which generates a significant economic burden of billions per year on the healthcare system. Chronic inflammation is known for its importance in the pathogenesis of atherosclerosis and CVDs. Currently, inflammatory hematologic indices, obtained through the results of the complete blood count (CBC), have been characterized as potential prognostic factors for mortality in CVD. These indexes are calculated from neutrophil, lymphocyte, platelet, and monocyte counts, are easily accessible, have simple calculations, and have low cost, which facilitates their application in practice. The aim of this paper was prepare a synthesis of studies that investigated the relationship of inflammatory hematologic indices with cardiovascular risk and mortality. The search was been conducted in PubMed, Scopus, Embase, Web of Science, and Virtual Health Library (VHL) databases. Studies that investigated the association between inflammatory hematologic indices with cardiovascular risk and mortality were been selected. 1,470 studies were obtained in the search, with only 23 being eligible. We found that the hematological index most associated with overall mortality, cardiovascular events, and cardiovascular mortality was the systemic immune-inflammation index (SII) followed by the systemic inflammatory response index (SIRI). The hematological inflammatory indices proved advantageous for screening and identifying patients who have high cardiovascular risk and mortality risk, and may be useful in directing the treatment of these patients, obtaining information about prognosis, and improving risk stratification.

Systematic review on molecular detection of congenital and neonatal infections caused by TORCH and SARS-CoV-2 in newborns' cerebrospinal fluid.

To verify the use and identify advantages of molecular methods for congenital infections diagnosis in cerebrospinal fluid of neonates. The review was registered in the International Prospective Register of Systematic Reviews (PROSPERO), under CRD42021274210. The literature search was performed in databases: PubMed, Virtual Health Library/ Latin American and Caribbean Center on Health Sciences Information (VHL/BIREME), Scopus, Web of Science, Excerpta Medica database (EMBASE), Cochrane, ProQuest, and EBSCOhost. The search was carried out from August to October 2021 and updated in December 2022, respecting the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The selection sequence was: 1) Duplicate title removal; 2) Examination of titles and abstracts; 3) Full-text retrieval of potentially relevant reports; and 4) Evaluation of the full text according to eligibility criteria by two independent authors. Inclusion criteria considered randomized and non-randomized control trials, longitudinal, cross-sectional, and peer-reviewed studies in humans, published in English, Spanish, Italian, and Portuguese, with newborns up to 28 days old who had congenital neuroinfections by toxoplasmosis, rubella, cytomegalovirus, herpes simplex (TORCH), and others such as Treponema pallidum, Zika, parvovirus B-19, varicella zoster, Epstein-Barr, and SARS-CoV2, diagnosed by polymerase chain reaction (PCR). Two evaluators extracted the following information: author, year of publication, nationality, subjects, study type, methods, results, and conclusion. The most studied pathogen was herpes simplex. Several articles reported only nonspecific initial symptoms, motivating the collection of cerebrospinal fluid and performing PCR for etiological investigation. Molecular methods are effective to detect pathogen genomes in cerebrospinal fluid, which can impact clinical evolution and neurological prognosis.

Quality of life after necrotizing enterocolitis: an integrative review.

To describe the long-term health outcomes of neonates affected by necrotizing enterocolitis (NEC) and its implications for quality of life. This is an integrative review, conducted by searching the literature in the following databases: Virtual Health Library (BVS), Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), and PubMed, using Health Sciences Descriptors (DeCS): "necrotizing enterocolitis," "quality of life," and "prognosis" combined with the Boolean operators AND and OR: "quality of life" OR "prognosis." Inclusion criteria were: publication period between 2012 and 2022. A total of 1,010 studies were located, of which ten were selected to comprise the bibliographic sample of this review. Children with NEC are prone to exhibit cognitive neurological impairment, especially those who undergo surgical procedures due to more severe conditions. Motor development was considered below average when compared to healthy children, with more noticeable delays in fine and gross motor function development. The search for the relationship between NEC and quality of life revealed that this condition has a negative impact on the well-being of affected individuals. NEC has proven to be a serious condition contributing to high rates of morbidity and mortality in newborns, potentially leading to a reduction in the quality of life of affected patients.

Risk factors associated with the occurrence of the adverse event phlebitis in hospitalized adult patients.

to synthesize knowledge regarding risk factors associated with occurrence of adverse event phlebitis in hospitalized adult patients. an integrative literature review, carried out in the CINAHL, PubMed, Virtual Health Library, Embase, Web of Science and Scopus databases. The stages were carried out independently by two reviewers, and the data were analyzed descriptively. from the analysis of 31 quantitative primary studies, the following risk factors were summarized: length of stay; use of antibiotics; peripheral intravenous catheter dwell time; receive less nursing care; catheter inserted multiple times; patients with infection and comorbidities; presence of pain at catheter insertion site; Teflon® catheter use; reduced patient mobility; quality of patient's vein; skin elasticity; unsuccessful insertion. it is necessary to standardize the format for measuring occurrence of this adverse event and develop new studies with a higher level of evidence.

VELOCIDADE DA MARCHA ASSOCIADA AOS FATORES CLÍNICOS EM IDOSOS NA ATENÇÃO PRIMÁRIA À SAÚDE: REVISÃO INTEGRATIVA

ABSTRACT Objective: to analyze national and international scientific production on gait speed associated with signs, symptoms, and clinical factors in elderly people in primary health care. Method: integrative literature review carried out in five data sources (Virtual Health Library, Embase, Web of Science, Cumulative Index To Nursing And Allied Health Literature (CINAHL), and PubMed) with publications from January 2017 to June 2023. Results: 13 publications met the eligibility criteria, with a predominance of studies in English. Studies indicated that reduced gait speed is associated with fractures (p<0.05), dementia (p<0.01), cardiovascular (p<0.001) and neuropsychiatric (p<0.01) diseases, falls (p<0.05) and polypharmacy (p<0.001). Conclusion: altered gait speed patterns in the older people are related to various clinical factors, reinforcing the need for further studies and the guiding role of the geriatric nursing team in the health of the older person.

Tuberculose na adolescência: uma revisão integrativa com foco no cuidado centrado no paciente

ABSTRACT Objective: To identify how patient-centered care has been addressed in tuberculosis studies with adolescents. Data source: We searched for articles published in Portuguese, Spanish and English in the Virtual Health Library (LILACS), PubMed (MedLine), and Scopus (Elsevier) databases, from 2000 to 2020, using descriptors (DeCS, MeSH) in Portuguese and English. Data synthesis: 1,322 studies were identified, of which 18 were selected. The main themes found were related to adherence to tuberculosis treatment, knowledge, attitudes and practices, health education, and public policies. Conclusions: We observed that both the number of researchers dedicated to the topic and the presence of a truly person-centered view are still scarce elements in tuberculosis among adolescents research.

Relational and functional aspects of safety for patients and caregivers in intensive care: scoping review.

To analyze the relational and functional aspects of patient safety through the experiences reported by the patients themselves and/or their caregivers in intensive care units. Scoping review developed with searches, in September 2021 and updated in November 2022, in the following databases: Virtual Health Library, considering only the LILACS, BDENF, IBECS, ColecionaSUS databases; SCIELO, PsycINFO, EMBASE, COCHRANE, CINAHL, SCOPUS and Web of Science. The final selection included 14 articles highlighting communication as an essential relational factor for care safety. The most predominant functional aspects were physical care environment, structured protocols, and the performance of professionals in the care process. Communication processes were predominant in relational aspects and were decisive for functional aspects, with emphasis on the performance of professionals in the care process. Instruments developed for quality process analysis were used in most of the studies.

TECNOLOGIAS EDUCACIONAIS PARA AUTOCUIDADO DE CRIANÇAS COM ANEMIA FALCIFORME: REVISÃO INTEGRATIVA

ABSTRACT Objective: To identify the educational technologies used to help children with sickle cell anemia in their self-care. Method: an integrative review carried out in six consecutive phases, between June and July 2023, with no time frame, in the following information resources: Public/published Medline, Virtual Health Library, Scientific Electronic Library Online, and Web of Science and Cumulative Index to Nursing and Allied Health Literature. Results: Five studies were found, of which the following stood out: a game, two electronic applications, a coloring book, and a guided image for pain relief. All the educational technologies reflect the child’s better understanding of self-care. Conclusion: The selected studies allowed us to understand that educational technologies help children with sickle cell anemia to understand the disease and take actions that improve its signs and symptoms, favoring self-care, but it is essential to create new educational technologies since most of the findings are old and do not match the current reality.

The effectiveness of telemedicine in the management of type 2 diabetes: A systematic review.

Type 2 diabetes, a lifestyle-related disease demanding daily self-management, is a significant health concern. In this context, the use of telemedicine as a management tool is a relatively new and promising approach. This study aims to contribute to the growing body of knowledge by identifying the effectiveness of telemedicine in managing type 2 diabetes through a systematic review approach. Four databases were searched including PubMed, Virtual Health Library, Global Health Library, and Google Scholar on 27 July 2022. Additionally, a manual search was performed to identify any relevant articles that may have been missed. The quality of the included articles was rigorously assessed using the Study Quality Assessment Tools of the National Institute of Health. We analyzed data from 134 articles. All 134 studies were published between 2002 and 2022, including 103 controlled intervention trials, 13 cohort studies, 7 before-after (pre-post) studies with no control group, 1 initial trial, 1 case study, 1 pilot study, and 8 two-arm studies that did not report the study design. Accordingly, most studies show positive changes in glycemic index in every group using telemedicine. Overall, although the BMI and weight indices in the studies improved at the end of the course, the improvement values were considered insignificant. Telemedicine may be a valuable solution for blood sugar management in patients with type 2 diabetes. However, the effectiveness of telemedicine in improving BMI and quality of life is unclear.

Transplantes de órgãos: abordagens éticas e soluções legais

Abstract This integrative literature review investigates legal aspects and ethical solutions involved in the illegal organ trade, an activity that sparks debates about ethics and morals. Bibliographical search was conducted on the Virtual Health Library, PubMed and SciELO databases. A total of 14 papers were analyzed, which pointed to low supply associated with high demand for organs as the main etiology of the problem. This market takes advantage of vulnerable populations to coerce them into organ donations. Additionally, the lack of connection between international databases and instabilities in countries with high trafficking rates hinders police action to confront this crime. Organ trafficking should be combated by encouraging legal organ donation, confronting “transplant tourism” and actions aimed at the most vulnerable countries. International entities play a fundamental role in ensuring that different nations work together to repress this type of crime.

Factors Associated with Suicide among Police Officers in Brazil: An Integrative Literature Review Study

The study aimed to identify factors associated with suicide among police officers in Brazil. This is an integrative literature review that was based on the following guiding question: "What are the factors associated with suicide among police officers in Brazil?". Searches were performed in November 2023 in the scientific databases Virtual Health Library (VHL) (https:// pesquisa.bvsalud.org/portal/) and PubMed (https://pubmed.ncbi.nlm.nih.gov/), from the search key: ((POLICE) AND (SUICIDE)) and (BRAZIL). The descriptors used were extracted from the Mesh/National Library of Medicine platform. Original articles published in the last 10 years that presented characteristics, profile and risk factors associated with suicide were included. Literature review studies, dissertations, theses, letters to the editor and articles in duplicate were excluded. The studies were published between 2007 and 2022. The sample consisted of quantitative descriptive studies (n=3), retrospective cohort (n=1) and ecological time series (n=1). The surveys had samples mostly composed of military police men; only one study investigated federal highway police. The factors associated with suicide and suicidal ideation among police officers in Brazil were financial complications, psychopathological comorbidities, male sex, young age and incipient career graduation.

RECUPERAÇÃO ENTRE SÉRIES NO TREINO DE FORÇA: REVISÃO SISTEMÁTICA E META-ANALISE

ABSTRACT Introduction: The recovery interval (RI) between sets and exercises has received attention from strength training (ST) researchers, to understand the relationship of rest on performance maintenance, especially the total load in a training session. It is known that each individual responds in a specific way to the training stimulus. So, what would be the effect of the different recovery interval strategies on the strength performance? Objective: Compare the different recovery intervals in strength training volume, considering the number of repetitions in healthy adults. Methods: We conducted a systematic review and meta-analysis based on methodological criteria, comparing fixed and self-selected RI on training volume, identified by the number of repetitions performed in a weight training program. Three electronic databases (Pubmed, VHL Virtual Health Library, Ebsco Sportdiscus) were analyzed, combining the expressions “resistance training”, “resistance exercise”, “strength exercise”, “recovery interval”, “rest interval”, “interval auto suggested”, “auto range selected” with “AND” and “OR” combination. Results: Pooled data from five studies showed a large significant effect in favor of the experimental group (>2 minutes) (MD: 1.24; 95%-CI [0.78; 1.71]; z: 5.25, Q:1.08; p < 0.01), since in the studies, recovery interval allowed a greater training volume. Conclusion: Longer RI seems be better, for maintaining total training volume, although there is no consensus for different training objectives against the self-selected RI. Thus, we imagine that this strategy may be important in the organizing a bodybuilding exercise program. Level of Evidence I; Systematic Review and Meta Analysis.

Intubação de sequência rápida em emergências pediátricas: uma revisão integrativa

Objectives: To identify up-to-date information that contributes to increasing the progress of rapid sequence intubation (RSI) in pediatric emergencies. Methods: This is an integrative literature review that used the keywords “Rapid Sequence Induction and Intubation”, “Intubation, Intratracheal” and “Pediatric Emergency Medicine” in the Scielo, PubMed and Virtual Health Library databases, using, after applying the inclusion and exclusion criteria, the content analysis for discussion. Results: We found 9 articles that were later discussed. Conclusions: Many health professionals do not correctly indicate medications during and after RSI in pediatric emergencies, and educational interventions aimed at correcting this failure are beneficial. An accurate epidemiological profile of RSI in pediatric emergencies cannot yet be established. The best way to collect data in studies involving RSI is through video recording. Interventions aimed at reducing the time spent during orotracheal tube insertion may more effectively reduce the total apnea time during RSI. The use of apneic oxygenation and fractional expired oxygen (FeO2) analysis may have some benefits in RSI.

Pulmonary Function in People Living With Human Immunodeficiency Virus: A Meta-Analysis

BackgroundHIV can infect bronchial epithelial cells rendering individuals susceptible to lung damage. Our objective was to determine the effects of human immunodeficiency virus (HIV) infection on pulmonary function tests. MethodsWe performed a meta-analysis after conducting a literature search in PubMed, Embase, Cochrane Library and Virtual Health Library databases from inception to December 31st, 2022. We employed the inverse variance method with a random effects model to calculate the effect estimate as the mean difference (MD) and 95% confidence interval (CI). We calculated the heterogeneity with the I2 statistic and performed a meta-regression analysis by age, sex, smoking, CD4 T-cells count and antiretroviral therapy. We also conducted a sensitivity analysis according to the studies’ publication date, and excluding the study with the greatest weight in the effect. The PROSPERO registry number was CRD42023401105. ResultsThe meta-analysis included 20 studies, with 7621 living with HIV and 7410 control participants. The pooled MD (95%CI) for the predicted percentage of FEV1, FVC and DLCO were −3.12 (−5.17, −1.06); p=0.003, −1.51 (−3.04, 0.02); p=0.05, and −5.26 (−6.64, −3.87); p<0.001, respectively. The pooled MD for FEV1/FVC was −0.01 (−0.02, −0.01); p=0.002. In all cases, there was a considerable heterogeneity. The meta-regression analysis showed that among studies heterogeneity was not explained by patient age, smoking, CD4 T-cells count or antiretroviral therapy. ConclusionPulmonary function tests are impaired in people living with HIV, independently of age, smoking, CD4 T-cells count, and geographical region.