VapoRub Research Articles

Ingredients of Vicks VapoRub inhibit rhinovirus-induced ATP release.

Over-the-counter therapies, such as Vicks VapoRub, are frequently used in the management of upper respiratory tract infection symptoms. Of these, acute cough is the most bothersome; however, the mechanisms involved have not been fully elucidated. The temperature-sensitive transient receptor potential (TRP) channels, including TRPA1, TRPV1, TRPM8 and TRPV4, are potential candidates. TRPV4 is also thought to be involved in cough through the TRPV4-ATP-P2X3 pathway. Here, we hypothesise that Vicks VapoRub ingredients (VVRIs) modulate the TRP cough channels. Stably transfected HEK cells expressing TRP channels were challenged with VVRIs, individually or in combination, and the agonist and antagonist effects were measured using calcium signalling responses. In addition, rhinovirus serotype-16 (RV16)-infected A549 airway epithelial cells were pre-incubated with individual or combinations of VVRIs prior to hypotonic challenge and extracellular ATP release analysis. Calcium signalling reconfirmed some previously defined activation of TRP channels by specific VVRIs. The combined VVRIs containing menthol, camphor and eucalyptus oil activated TRPV1, TRPV4, TRPM8 and untransfected wild-type HEK293 cells. However, pre-incubation with VVRIs did not significantly inhibit any of the channels compared with the standard agonist responses. Pre-incubation of RV16-infected A549 cells with individual or combined VVRIs, except menthol, resulted in a 0.45-0.55-fold reduction in total ATP release following hypotonic stimulation, compared with infected cells not treated with VVRIs. These findings suggest that some VVRIs may reduce symptoms associated with upper respiratory tract infection by modulating specific TRP receptors and by reducing RV16-induced ATP release.

Patient perspectives of wound care management in hidradenitis suppurativa.

Wound care management and costs in hidradenitis suppurativa (HS) are unmet needs. This study explored patient perspectives of at-home management of acute flares of HS and chronic daily wounds, their satisfaction with current wound care methods, and the financial burden of wound care supplies. An anonymous, multiple choice, cross-sectional questionnaire was distributed among online HS-related forums between August and October 2022. Participants 18years or older with a diagnosis of HS who live in the United States were included. In total, 302 participants completed the questionnaire: 168 White (55.6%), 76 Black (25.2%), 33 Hispanic (10.9%), 7 Asian (2.3%), 12 multiracial (4.0%), and 6 other (2.0%). Dressings commonly reported included gauze, panty liners or menstrual pads, tissues or toilet paper, antiseptic dressing, abdominal pads, and adhesive bandages. Commonly reported topical remedies for acute flares of HS included warm compresses, Epsom salt baths, Vicks VapoRub, tea tree oil, witch hazel, and bleach baths. One-third of participants (n = 102) reported dissatisfaction with current wound care methods, and 48.8% (n = 103) believed that their dermatologist does not meet their wound care needs. Nearly half (n = 135) reported being unable to afford the type and quantity of dressings and wound care supplies they would ideally want. Black participants were more likely than White participants to report being unable to afford their dressings and find the cost as very burdensome. Overall, dermatologists must improve patient education of wound care methods in HS and address the financial burden of wound care supplies by exploring insurance-funded options.

Multi-Symptom Relief for Cough & Cold: Benefits of Adding Vicks VapoRub to the Treatment Regimen

Multi-Symptom Relief for Cough & Cold: Benefits of Adding Vicks VapoRub to the Treatment Regimen

Otorhinolaryngological Manifestations and Its Management in COVID 19 Patients.

COVID 19 pandemic is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The first case was identified in December 2019, in Wuhan, China. It is an infectious disease and has led to the ongoing global pandemic. This pandemic has also started in Assam, with its first case reported on 31 March, 2020. A prospective study was conducted on 2000 laboratory confirmed coronavirus cases. Proper history were taken and clinical examinations were performed. They were also advised to do the necessary blood investigations, electrocardiogram and chest X- rays. Olfactory functions were assessed using substances like scented soap, mint toothpaste, vicks vaporub, etc. Gustatory functions were also assessed. In our study, we found that 83% (1650) patients presented with otorhinolaryngological or ENT (Ear, nose, throat) manifestations and 17% (350) did not have any otorhinolaryngological manifestations. The most common ENT symptoms with which the patients presented were sore throat (80%) and headache (76%). The other ENT symptoms were hyposmia (44%), dysgeusia (32%) and nasal congestion (28%). The most common non-ENT symptoms were fever (92%) and cough (85%). The other non-ENT symptoms with which the patient presented were malaise, generalized bodyache and abdominal symptoms (like diarrhea). This prospective study gives a view of the incidence of otorhinolaryngological manifestations in COVID 19 patients. But, no significant co-relation was seen between presence of ENT symptoms and the severity of the disease. However, further studies are required to know the pathogenesis of causing ENT symptoms properly and also for definitive treatment of these symptoms.

The common cold

Many people experience colds during the fall. A cold is a viral infection of the upper respiratory tract and is one of the top five diagnosed conditions in the United States. They are the leading cause of work and school absenteeism. Most colds are self-limiting—symptoms usually resolve on their own in 7 to 14 days. The objectives of self-treatment are to reduce symptoms, improve functioning and sense of well-being, and prevent spread of the disease. Nonpharmacologic therapy is the mainstay of treatment. Because symptoms appear, peak, and resolve at different times, a stepwise approach using single-entity products targeting specific symptoms is preferable to the use of combination products. Patient education regarding the administration of I.N. and ocular drugs is important. Although evidence of efficacy is lacking, popular therapies include increased fluid intake, adequate rest, a nutritious diet as tolerated, and increased humidification with steamy showers, vaporizers, or humidifiers. Saline nasal sprays or drops moisten irritated mucosal membranes and loosen encrusted mucus. Salt gargles may ease sore throats. Hot tea with lemon and honey, chicken soup, and vegetable and other broths are also soothing. Medical devices, such as Breathe Right nasal strips, are marketed for temporary relief from cold- and allergy-related nasal congestion and stuffiness. These lift the nares open and enlarge the anterior nasal passages. Aromatic oils (e.g., camphor, menthol, eucalyptus) in products such as Vicks VapoRub (for patients aged 2 years and older) also ease nasal congestion and improve sleep by producing a soothing sensation. Nondrug therapy for all patients includes upright positioning to enhance nasal drainage. Proper hand hygiene reduces the transmission of cold viruses and is especially important during the current COVID-19 pandemic. Decongestants treat sinus and nasal congestion. They are adrenergic agonists (sympathomimetics) that constrict blood vessels, thereby decreasing sinusoid vessel engorgement and mucosal edema. Direct-acting (e.g., phenylephrine, oxymetazoline, tetrahydrozoline) bind directly to adrenergic receptors; indirect-acting (e.g., ephedrine) displace norepinephrine from storage vesicles in prejunctional nerve terminals; and mixed (e.g., pseudoephedrine) have both direct and indirect activity. Rhinitis medicamentosa (RM)—that is, rebound congestion—has been associated with use of topical decongestants. Depending on the active ingredient, therapy of 3 to 7 days is the accepted duration to avoid RM. Decongestants interact with numerous drugs including MAOIs, ergot derivatives, serotonin/norepinephrine reuptake inhibitors, anticholinergic agents, some antivirals, and others. Decongestants may exacerbate diseases sensitive to adrenergic stimulation, such as hypertension, coronary heart disease, ischemic heart disease, diabetes mellitus, hyperthyroidism, elevated intraocular pressure, and prostatic hypertrophy. Certain patients may use other products such as antihistamines, local anesthetics, systemic analgesics, and antitussives to treat cold symptoms such as sore throat, aches, fever, and nonproductive cough. Combination products are highly marketed and may be convenient, but this benefit must be weighed against the risks associated with taking unnecessary drugs. Drug use during pregnancy and lactation requires a balance between risk and benefit. Because most colds are self-limiting, many providers recommend nondrug therapy for treatment of bothersome but not life-threatening symptoms. FDA does not recommend nonprescription cold medications for children younger than 2 years because of the lack of efficacy and risk of misuse or overuse leading to adverse events and death. Providers should emphasize nondrug measures in children; if pharmacotherapy is necessary, parents should follow dosing instructions carefully and avoid combination products. FDA requires all liquid products to include a measuring device. When selecting a product, consider patient references, such as product formulation, flavor, frequency of use, and safety. Numerous complementary therapies are marketed for cold symptom management, including zinc and vitamin C. In vitro studies have shown these have a modest antiviral effect at best, and efficacy data remain inconclusive. Products that claim to strengthen the immune system such as Airborne, Emergen-C Immune+, and others have not been proved to be effective in preventing or treating colds. Not all patients should self-treat their colds. Those who have a temperature above 100.40F, are experiencing shortness of breath, have an underlying chronic cardiopulmonary condition, are frail or older adults, and infants aged 3 months or younger should be referred to their primary care provider.

Topical ayurvedic ointment-induced chemical injury presenting as bilateral acute keratitis

A 40-years-old female patient was referred to the cornea clinic as a probable case of bilateral keratitis. The patient had a history of headache followed by acute onset of redness,...

Efficacy of a Topical Aromatic Rub (Vicks VapoRub<sup>®</sup>) on Effects on Self-Reported and Actigraphically Assessed Aspects of Sleep in Common Cold Patients

Common cold sufferers frequently report sleep disruption during the symptomatic period of infections. We examined the effects of treatment with a topical aromatic pharmaceutical ointment (Vicks VapoRub®), on associated sleep disturbances. The effects of Vicks VapoRub® versus placebo (petrolatum ointment) on subjective and objective measured sleep parameters were assessed in an exploratory study of 100 common cold patients, in a randomized, single blind, controlled, two-arm, parallel design study. The primary efficacy variable was subjective sleep quality measured with the SQSQ (Subjective Quality of Sleep Questionnaire). Additional measures included, ease of falling asleep and depth of sleep (measured with a post-sleep Visual Analog Scale), total sleep time, sleep onset latency, activity score, percentage of sleep, sleep efficiency (measured with actigraphy and SQSQ) and sleep quality index measured with a modified Karolinska Sleep Diary (KSD). The primary endpoint, “How was the quality of your sleep last night?” showed a statistically significant difference in change from baseline in favour of VapoRub treatment (p = 0.0392) versus placebo. Positive effects of VapoRub versus placebo were also observed for “How refreshed did you feel upon waking up?” (p = 0.0122) (SQSQ), “Did you get enough sleep?” (p = 0.0036) (KSD), “How was it to get up?” (p = 0.0120) (KSD) and “Do you feel well-rested?” (p = 0.0125) (KSD). No statistically significant changes from baseline versus placebo were detected in the Actiwatch endpoints. Vicks VapoRub® when applied before retiring to bed can reduce subjective sleep disturbances during a common cold. The results of this exploratory study support the belief among patients that the use of VapoRub improves subjective sleep quality during common cold which was associated with more refreshing sleep.

Practices during Common Cold and Ear Ache in Children among the Koraga Tribes: A Descriptive Survey

Background: Common cold and ear ache are one of the major problems which occur due to infection in children. Tribal populations use different practices to get rid of these infections. Objectives: The objective of the study was to assess the practices of the Koraga tribes during common cold and ear ache in children. Materials and Method: The study used a descriptive survey approach to collect data from 200 Koraga tribal care takers using a practice questionnaire. The data was analysed using SPSS 16.0 software. Results: Majority 110 (55%) of caretakers were using pepper, 49 (24.5%) were using lemon and honey mixture and 19 (9.5%) were using ginger for common cold. Other practices include applying Vicks vaporub over forehead, nose and neck 156 (78%), using pepper and black cumin kashayam 21 (10.5%) and samabarbelle leaves 23 (11.5%). Practices during ear ache in children includes, 96 (48%) of caretakers were not practicing any home remedies, 58 (29%) putting oil into the ear, 14 (7%) putting water into the ear and 32 (16%) of sample were observing and cleaning the ear with soft cotton. Other practice includes dry fish water into the ear 11 (5.5%). Conclusion: The study concluded that majority of Koraga tribes still practice many home remedies to treat the children with common cold and ear ache.

Camphor poisoning presenting as acute diffuse demyelination of brain

Camphor is a colorless substance available in solid and liquid form. Volatile oil form of camphor is the active ingredient of Vicks Vaporub, and Tiger Balm ointments. These ointments are commonly used as home remedies for treatment of cough, cold and for topical analgesics. They are inexpensive, over the counter remedies, hence widely used in India. Neurological complication due to camphor toxicity reported is headache, mental confusion and seizures. Here we report, a case of diffuse white matter lesions in a young female due to accidental camphor inhalation while working in factory that manufactures vicks and tiger balm. The case highlights camphor as a possible cause of toxic demyelination hence potentially exposed workers should be educated about health and safety measures to prevent such complication.

Efficacy of a Topical Aromatic Rub (Vicks VapoRub<sup>®</sup>)-Speed of Action of Subjective Nasal Cooling and Relief from Nasal Congestion

Vicks VapoRub® (VVR) is a pharmaceutical preparation containing a combination of levomenthol, eucalyptus oil, turpentine oil and camphor as active ingredients, and thymol, cedarwood oil, and white soft paraffin as excipients. VVR is a petrolatum-based ointment to be either applied topically to the chest, throat, and back or added to hot water and the aromatic vapours inhaled. When used topically, the actives are evaporated by body temperature and inspired. The main therapeutic effects are the feeling of relief from nasal congestion and relief from cough. These were primarily experienced by patients as the trigeminal and olfactory impact of the aromatics and were hypothesized to be experienced within minutes. This was a randomized, single-(Investigator) blind, controlled, 2-arm (VVR vs. petrolatum), parallel design pilot study in 50 otherwise healthy adult patients suffering from common cold and experiencing nasal congestion. Speed to detection of a sensation of nasal cooling and nasal decongestion was assessed following application of the recommended amount of product. The time to first experience of a sensation of nasal cooling was significantly (p < 0.001) faster for patients who received VVR compared to control (median times of 23 and 99 seconds respectively). VVR delivered a statistically significant sensation of nasal cooling at all times from 12 seconds to 15 minutes after product application. The time to first experience of a sensation of nasal decongestion was significantly (p = 0.0102) faster for patients who received VVR compared to control (median times of 62 and 126 seconds respectively). VVR delivered a statistically significant sensation of nasal decongestion at all times from 62 seconds to 15 minutes after product application. No adverse events were reported during the study. Conclusion: Patients using Vicks VapoRub® as directed experienced significant differences from control for sensation of nasal cooling in 12 seconds and the sensation of nasal decongestion in 62 seconds.

Evaluation of the full evaporation technique for quantitative analysis of high boiling compounds with high affinity for apolar matrices

In order to reduce inaccuracies due to possible matrix effects in conventional static headspace-gas chromatography (sHS-GC), it is standard practice to match the composition of calibration standards towards the composition of the sample to be analysed by adding blank matrix. However, the latter is not always available and in that case the full evaporation technique (FET) could be a solution. With FET a small sample volume is introduced in a HS vial and compounds of interest are completely evaporated. Hence no equilibrium between the condensed phase and vapour phase exists. Without the existence of an equilibrium, matrix effects are less likely to occur. Another issue often encountered with sHS-sampling is that low vapour pressure compounds with a high affinity for the dilution medium show a limited sensitivity. FET has proven to be an appropriate solution to address this problem too.In this work, the applicability of FET for the quantitative analysis of high boiling compounds in different complex apolar matrices is examined. Data show that FET is an excellent tool to overcome matrix effects often encountered with conventional sHS analysis. The tested method shows excellent accuracy with recovery values around 100% as well as repeatability with RSD values around 1% for the quantification of high boiling compounds (bp>200°C) such as camphor, menthol, methyl salicylate and ethyl salicylate in various matrices. LOQ values were found to be around 0.3μg per vial. Following validation of the technique, several topical pharmaceutical formulations like ThermoCream®, Reflexspray®, Vicks Vaporub® and Radosalil® were examined. For the latter, a comparison has been made with a sHS-method described in literature.

Dark &amp; Raw

Dark & Raw John Griswold (bio) Crapalachia: A Biography of a Place Scott McClanahan Two Dollar Radio www.twodollarradio.com/ 192 Pages; Print $16.00 Hill William Scott McClanahan Tyrant Books www.nytyrant.com/books.html 200 Pages; Print $11.94 Scott McClanahan grew up in one of those provinces in the American empire where natural resources are removed to the detriment of the land and for the enrichment of somebody else. His West Virginia is the sort of place where old matriarchs apply Vicks VapoRub and ghost stories as medicine, and wild dumbasses—friends, neighbors, relatives—provide comic relief and horror. A chapter in the memoir Crapalachia is called “Crazy Fuckers I Knew,” and McClanahan’s Uncle Nathan, incapacitated by cerebral palsy, asks young Scott to pour a six-pack down his feeding tube directly into his stomach. Crapalachia has many suggestions of region: A hog that bites off a sick cat’s head, a quilt-peddling granny, a mountain graveyard, moonshine shacks, a denied mine pension. But with the exception of an ironic mention of a couple of “accidents of history” (the Sago mine disaster and Buffalo Creek Flood) that kept West Virginia down, this “Biography of a Place” mostly ignores politics, labor, economics, race, ethnicity, and the environment. What it does contain is plenty of tales about people McClanahan says he’s known. These tales are McClanahan’s lights, in two meanings: His big talent lies in finding them, and their quickness on the page moves things along. They could easily be short stories in his earlier collections—a ceremonial dove, meant to represent the soul, won’t fly when released at the funeral, obstinate as dead Grandma Ruby was in life. A guy becomes obsessed with a girl because, “She wasn’t ignoring him like everyone else and that’s all it took;” Uncle Leslie “kick(s) the fuck out of The Toughest Man in Fayette County,” when Leslie is eleven—but here McClanahan strings them together, mostly successfully. One chapter ends with suffering Uncle Nathan looking sad, and McClanahan empathetically imagines, “It was like he was thinking about graveyards again.” The next chapter, titled “Graveyards,” is about a visit to a graveyard with McClanahan, Grandma Ruby, her son Nathan, and yet another uncle. (Ruby had thirteen children. More on that later.) These tales, with their simple syntax and diction, have attracted a growing audience and allowed McClanahan to avoid the trap of regionalism. The prose may be more the product of Internet and pop culture anyway, with its slightly flat, alienated, but good-natured tone that’s more Kurt Vonnegut than Harry Caudill. Characters are preoccupied with the “outside world”—soap operas, movies, pro wrestling, porn—that’s already their own dirty-realist world. Crapalachia, like the story collections, is also laced with comic-book or graphic novel sensibilities, such as typographical onomatopoeia (“Tick, tick, tick, tick, tick...”) biff-bam-pow interruptions of story (“BUT STOP!”), and exclamations by the narrator (“SHIT!”) that serve as meta-commentary on the progress of the narrative itself. McClanahan’s smart, scatological jumble may have kept him (so far) out of the hands of corporate publishers, whose editorial and marketing resources he deserves. One is as likely to find in Crapalachia teen lore of a turd left in the principal’s desk drawer by a friend, snickers over crotchless panties, or a joke about the obese, as to find an epigraph by Robert Penn Warren, a possible nod to Joyce, or a phrase such as, “vague family parameters.” In some ways, McClanahan is a manifestation of David Foster Wallace’s prophecy that writers in the new millennium would try to have their po-mo irony and eat it too: “The quilt wasn’t a fucking symbol of anything. It was something [Grandma Ruby] made to keep her children warm. Remember that. Fuck symbols.” The prose can be powerfully affecting. Nathan asks his nephew to shoot him, as assisted suicide: “I giggled but then I stopped. He wasn’t joking.” But it can also be sentimental enough to melt your Hershey bar: “There is enough fire burning inside my secret heart to keep [a list of people] warm for a long...

English

INTRODUCTION: Lunsford Richardson developed the formula in 18941.When he created a salve for his children after travelling to France and he named the product for his brother-in-law Dr.Joshua Vick. A Penn state study showed Vicks Vaporub to be effective in helping to reduce nasal congestion i.e seen in common cold (coryza) and thus reduce cough in both children and adults2. Vicks Vaporub is an effective cough medicine for Guinea pigs3. Vicks Vaporub has also been used in the treatment of onychomycosis (fungal infection of nail)4. ACTIVE INGREDIENTS: Label reads: special vick medications (camphor, menthol, spirits of turpentine, eucalyptus oil, cedar leaf oil, thymol, myristica oil) compounded by the original vick process. Camphor (4.8%) cough suppressant and topical analgesic. Eucalyptol (1.2%) cough suppressant. Menthol (2.6%) cough suppressant and topical analgesic. INACTIVE INGREDIENTS: Cedar leaf oil, Nutmeg oil, Turpentine oil, special petrolatum.

New Concepts in Median Nail Dystrophy, Onychomycosis, and Hand, Foot, and Mouth Disease Nail Pathology

Nails are underutilized as diagnostic tools, despite being involved in many dermatologic conditions. This paper explores new concepts in the treatment of median nail dystrophy (MND), onychomycosis, and the nail pathology of hand, foot, and mouth disease (HFMD). A Pubmed database literature search was conducted for MND treatment, onychomycosis treatment, and HFMD nail pathology. Only papers published after January 2008 were reviewed. The results showed that 0.1% tacrolimus ointment can be an effective treatment for MND. Early studies on laser therapy indicate that it is a safe and efficacious treatment option for onychomycosis, compared to conventional oral antifungal agents. Vicks VapoRub (The Proctor & Gamble Company, Cincinnati, OH) is effective against onychomycosis and is a reasonable option in patients who choose to forgo conventional treatments. Lastly, there is evidence to support a correlation between HFMD and onychomadesis.

Vapor Rub Better Than Petrolatum &amp; No Treatment for Cold Symptoms

Vapor Rub Better Than Petrolatum &amp; No Treatment for Cold Symptoms

The Great Wall of Lucy Wu (review)

Reviewed by: The Great Wall of Lucy Wu Kate Quealy-Gainer Shang, Wendy Wan -Long . The Great Wall of Lucy Wu. Scholastic, 2011. [320p]. ISBN 978-0-545-16215-9 $17.99 Reviewed from galleys R Gr. 4-6. Sixth grade is going to be the best year of eleven-year-old Lucy Wu’s life. Or at least so it seems, until her parents inform her that Yi Po, her grandmother’s sister from China, will be staying with Lucy’s family until Christmas. Now Lucy has to give up half of her bedroom to an old lady who smells like Vicks VapoRub and gets up at the crack of dawn—and who is not and never will be Po Po, Lucy’s beloved, recently deceased grandmother. To make matters worse, Lucy’s parents are making Lucy attend Chinese school in an effort to get their American-born daughter to better respect her heritage, and they are threatening to forbid her from playing her beloved basketball if her attitude does not improve. Most readers will know where this is going, but the book’s predictability is not necessarily a fault here, rather just another comfortable element of a cozily hopeful exploration of family dynamics and cultural history. Yi Po’s gentle sense of humor and serious cooking skills inevitably win her grandniece over, and Lucy realizes that a connection to Yi Po is an honor, not a rebuke, to her grandmother’s memory. Though the relationship between Lucy and Yi Po is front and center in the story, Shang also capably portrays the family as a whole, presenting a fully realized unit that has both smooth and rough times. Bits of Chinese history and culture as well as allusions to incidents of prejudice and racism are effectively integrated without melodrama, leaving the focus entirely on Lucy’s preteen and familial experience. Her struggle to determine what and who is important to her will most certainly resonate with young readers. [End Page 298] Copyright © 2011 The Board of Trustees of the University of Illinois

Novel Treatment of Onychomycosis using Over-the-Counter Mentholated Ointment: A Clinical Case Series

current medication treatments for onychomycosis have less than full cure-rate efficacy and have the potential for adverse side effects. Vicks VapoRub (The Proctor & Gamble Company, Cincinnati, OH) has been advocated in the lay literature as an effective treatment for onychomycosis. This pilot study tested Vicks VapoRub as a safe, cost-effective alternative for treating toenail onychomycosis. eighteen participants were recruited to use Vicks VapoRub as treatment for onychomycosis. Participants were followed at intervals of 4, 8, 12, 24, 36, and 48 weeks; digital photographs were obtained during initial and follow-up visits. Primary outcome measures were mycological cure at 48 weeks and clinical cure through subjective assessment of appearance and quantifiable change in the area of affected nail by digital photography analysis. Patient satisfaction was a secondary outcome, measured using a single-item questionnaire scored by a 5-point Likert scale. fifteen of the 18 participants (83%) showed a positive treatment effect; 5 (27.8%) had a mycological and clinical cure at 48 weeks; 10 (55.6%) had partial clearance, and 3 (16.7%) showed no change. All 18 participants rated their satisfaction with the nail appearance at the end of the study as "satisfied" (n = 9) or "very satisfied" (n = 9). Vicks VapoRub seems to have a positive clinical effect in the treatment onychomycosis.

My Mother Was Right About VapoRub

Many of us can recall the use of Vicks VapoRub during childhood. In a manufacturer-sponsored study, 138 children (age range, 2–11 years) seen at a

Contact Dermatitis to Vicks VapoRub

Vicks VapoRub (VVR) is a commonly used inhalant ointment that helps relieve symptoms of upper respiratory tract infections. It contains several plant substances, including turpentine oil, eucalyptus oil, and cedar leaf oil, which can potentially irritate or sensitize the skin, as well as camphor, menthol, nutmeg oil, and thymol. Although many reports describe allergic contact dermatitis (ACD) to the various constituents in VVR ointment, there are no cases of VVR directly causing ACD. We present a case of a patient who developed an ACD secondary to application of her VVR.

Vicks VapoRub Induces Mucin Secretion, Decreases Ciliary Beat Frequency, and Increases Tracheal Mucus Transport in the Ferret Trachea: Abanses JC, Arima S, Rubin BK. Chest 2009;135:143–8

Vicks VapoRub Induces Mucin Secretion, Decreases Ciliary Beat Frequency, and Increases Tracheal Mucus Transport in the Ferret Trachea: Abanses JC, Arima S, Rubin BK. Chest 2009;135:143–8