ContextSemi-arid tropics is facing serious issues of malnutrition in population owing to poor quality of food grain production. Malnutrition is directly linked to lower grain protein and zinc yield due to inappropriate land and water, and nutrient management practices, which also resulted into reduced nitrogen use efficiency (NUE) in cereals. ObjectiveThe objectives of the study were to evaluate the effect of land and water and nutrient management on grain protein and zinc yield, and NUE of cereal-based cropping systems on vertisols soils in semi-arid tropics. MethodsThe study was carried out at Hyderabad in India during 2014–15 and 2015–16 and involved three cropping systems (two rotation systems: sorghum-chickpea and maize-groundnut; and one intercropping: pearl millet + pigeonpea), two land and water management i.e. flatbed and broad bed furrows and four nutrient management-N1: Control (no fertilizer), N2: 100% recommended application of macronutrient (nitrogen, phosphorus and potassium) through chemical fertilizer, N3: N2 + 100% recommended application of secondary nutrient (sulphur) and micronutrient (zinc and boron) through chemical fertilizer, and N4 (integrated nutrient): 50% of N2 + 50% nitrogen in cereals or phosphorus in legumes through organic fertilizer as vermicompost. ResultsIn sorghum-chickpea rotation system, the treatment interaction broad bed furrows with 100% recommended application of macronutrient, secondary nutrient and micronutrient recorded significantly higher grain zinc yield in both the years, while grain protein yield was significantly higher in second year. The grain protein and zinc yield in sorghum-chickpea rotation system, and agronomic nitrogen use efficiency in pearl millet+pigeonpea intercropping system was significantly higher in broad bed furrows than flatbed. The agronomic NUE of broad bed furrows was higher by 61% in 2014–15 and 65% in 2015–16 over flatbed. Among the nutrient management treatments, grain protein and zinc yield, and agronomic NUE were significantly higher in combined application of macronutrient, secondary nutrient, and micronutrients through chemical fertilizer i.e. N3 followed by N4, N2 and N1. ConclusionThe broad bed furrows and application of macronutrient, secondary nutrient and micronutrient could be an effective integrated land and water and nutrient management approach to improve grain quality and agronomic nitrogen use efficiency of cereal-based cropping systems in semi-arid tropics. ImplicationsThis study contributed to develop integrated land and water and nutrient management as an innovative agronomic management practice for cereal-based cropping systems, which needs to scale-up through Government agricultural policies to overcome the issue of malnutrition in population living in semi-arid tropics.