The wavy flow of generalized fluid namely, Cross fluid is mathematically formulated on a gravitationally affected vertical wavy surface with significant physical effects which is the main theme of this work. This particular dynamics of chemically reactive materials is further explored with an irreversible process. A significant heat transfer is measured through thermal resistance during the consideration of entropy optimization. Since entropy generation is associated with the mechanical systemenergy loss is more helpful in monitoring the entropy production in different engineering and industrial processes. Specifically, such irreversibility process appearance causing a noticeable low efficiency in the relevant practical sectors. For better performance in the minimization of friction on the wavy surface, flow is dissipated in terms of heat. However, the measure of loss in terms of work is introduced in the form of thermal radiation, viscous dissipation, magnetic field, and first-order chemical reaction. Additionally, the expected pressure drooping on the wavy surface is another goal of the entire study. The non-linear mathematical equations are determined by following the maximum viscosity approach. Relevant and important results are portrayed to show the various features of the newly developed work. The significant findings are approximated via one of the collocation methods while using MATLAB software. The Richardson number and buoyancy parameter enhanced the flow speed of the materials. The heat transfer rate is decreased by both Eckert number and wavy amplitude and the chemical reaction factor enhanced the mass transfer rate. The heat energy of the materials is escalated with the help of electromagnetic wave radiation and temperature ratio factor. Strengthening the chemical reaction factor declined the mass flow during the typical motion of the liquid. In the last, a comparison is provided to show the accuracy of the numerical approach.
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