Mesoscale oceanic eddies are known to influence air-sea interactions during tropical cyclone (TC) passage by either hindering or sustaining air-sea fluxes into the TC core. However, little is known as to how TCs alter the dynamical structure of such eddies during and after TC passage. Through simulations of Hurricane Irma (2017) using the Navy’s Coupled Ocean Atmospheric Mesoscale Prediction Scheme for Tropical Cyclones, it is found that a simulated mesoscale warm core eddy (WCE) located to the right of the model track disappeared shortly after the TC had passed over it. To further explore this phenomena, time series of ocean kinetic energy, available potential energy (APE), a vorticity budget, and a potential vorticity (PV) budget are examined to understand how TC-induced upper ocean currents influenced the eddy disappearance. Time series of APE within the model-simulated eddy show APE reaching a minimum as the circulation of the eddy disappeared in the model field and positive vorticity, dominated by vertical vorticity advection, became a maximum approximately 6 h after TC passage. These results were confirmed by the PV budget. The succession of subsurface vorticity changes suggest that the WCE was eradicated by a near-inertial wave wake that occurred earlier than expected. As found in a prior study, the early-onset of a near-inertial wake occurs when the model simulated TC with a small radius of maximum winds interacts with the subsurface ocean current field. The findings are important with regards to TC forecasting because the accurate representation and placement of eddies in the model field is necessary to correctly predict the coupled air-sea response during TC passage and for subsequent TCs with similar tracks. Such feedbacks from TCs can also have near-term and long-term influence on the prediction of air-sea interaction in the local and regional marine environment.