Venom Of Philanthus Triangulum Research Articles

Effects of the venom of the solitary wasp Philanthus triangulum F. on glutamate uptake in the nerve endings of locust muscles—A high resolution autoradiographic study

Using electron microscope autoradiography it was shown that the glutamate uptake in both glia cells and axon in the synaptic region of locust muscles was reduced to ca. 50% under the influence of the venom of the solitary wasp Philanthus triangulum F. However, the ratio of the glutamate accumulation in the glia and the nerves remained identical. Implications are discussed in relation to known postsynaptic effects of the venom of Philanthus triangulum F.

Neuromuscular block in insects caused by the venom of the digger wasp philanthus triangulum F.

1. 1. The venom of Philanthus triangulum F. blocks the excitatory and inhibitory neuromuscular transmission, with a concurrent decrease in size of the excitatory and inhibitory post-synaptic potentials. 2. 2. It causes a decrease in frequency of the excitatory and inhibitory miniature potentials without influencing their amplitude to any significant extent. 3. 3. This leads to the conclusion that the venom presynaptically inhibits the release of transmitter substances, possibly in a relatively aspecific manner.