Various Types Of Nanoparticles Research Articles

Functionalized Carbon Nanotubes: An Advanced Tool with Enhanced Biomedical Attributes

Background: The drug delivery system is revolutionized by nanoparticles, an essential component of nanotechnology, exhibiting an ultra-small size, large surface area to mass ratio, and high reactivity, different from bulk materials having the same composition. Various types of nanoparticles include liposomes, neosomes, micelles, carbon-based, etc. The most useful among them are carbon nanotubes because of their distinct optical, electrical, thermal, and mechanical properties and their architectures. Furthermore, the carbon nanotubes could either be single-walled or multiple-walled, based on the number of graphene sheets rolled. Like any other technique, these come with many limitations, including their tendency of hydrophobicity, insolubility, bundling together, low dispersibility, and, majorly toxicity. Objective: In this review, the main objective is to update the applications of functionalized carbon nanotubes as drug delivery systems in various therapies. Methods: Functionalization came into being to solve the mentioned disabilities. Functionalization could be covalent as well as non-covalent. As a result, functionalized carbon nanotubes have shown improvement in mentioned drawbacks. Conclusion: Now, the above-said functionalized carbon nanotubes have achieved bigger objectives with a better approach than conventional carbon nanotubes in the field of drug delivery systems.

Application of nanoparticles as surface modifiers of dental implants for revascularization/regeneration of bone

BackgroundOsseointegrated dental implants are widely established as a first-choice treatment for the replacement of missing teeth. Clinical outcomes are however often compromised by short or longer-term biological complications and pathologies. Nanoparticle-coated materials represent a very active research area with the potential to enhance clinical outcomes and reduce complications of implant therapy. This scoping review aimed to summarize current research on various types of nanoparticles (NPs) used as surface modifiers of dental implants and their potential to promote biological and clinical outcomes.MethodsA systematic electronic search was conducted in SCOPUS, PubMed and Google Scholar aiming to identify in vivo, in situ, or in vitro studies published between 2014 and 2024. Inclusion and exclusion criteria were determined and were described in the methods section.ResultsA total of 169 articles (44 original papers from Scopus and PubMed, and 125 articles from Google Scholar) were identified by the electronic search. Finally, 30 studies fit the inclusion criteria and were further used in this review. The findings from the selected papers suggest that nanoparticle-coated dental implants show promising results in enhancing bone regeneration and promoting angiogenesis around the implant site. These effects are due to the unique physicochemical properties of nanoparticle-coated implants and the controlled release of bioactive molecules from nanoparticle-modified surfaces.ConclusionNanoscale modifications displayed unique properties which could significantly enhance the properties of dental implants and further accelerate revascularization, and osseointegration while facilitating early implant loading. Yet, since many of these findings were based on in-vitro/in-situ systems, further research is required before such technology reaches clinical application.

Assessment of the Effects of Nanofuels on Combustion and Emissions in a Diesel Engine by Considering Various Types of Nanoparticles in Combination with Biodiesel or Ethanol

Assessment of the Effects of Nanofuels on Combustion and Emissions in a Diesel Engine by Considering Various Types of Nanoparticles in Combination with Biodiesel or Ethanol

Overview on Nanomaterials for Nanocosmetics

One of the scientific areas with the highest growth right now is nanotechnology. The development of nanocosmetics through the use of nanoscale materials has become more popular in recent years. Due to distinct structures, chemical, physical, physiochemical, and functional properties - most of them are absent in their non-nanoscale forms - some nanomaterial types are extremely appealing for use in the cosmetics sector. Regardless of their kind, form, morphology, or content, nanomaterials have two primary purposes in cosmeceutical inventory [1]: nano-constructs as (UV) filters, and [2] nanostructures as biologically active components for topical applications and other treatments associated with cosmeceuticals, such as moisturizers, skincare, makeup, sunscreen, and hair care products. As Ultraviolet filters or Ultraviolet protectants, various types of nanoparticles, such as silver, gold, titanium, and zinc, have been employed in the former scenario to hinder or to Utilize UV radiation and shield the layer beneath the skin from damaging consequences. Nanoliposomes are the delivery systems used in the 2nd concept usage. Therefore, next-generation cosmeceutical solutions for blossoming beauty that offer enhanced skin hydration, bioavailability, agent stability, and regulated UV occlusion have been highlighted as potentially becoming nanomaterial-loaded nanocosmetics. In light of the criticisms mentioned earlier and the potentialities of nanomaterials, we first examined the benefits of using nanoliposomes and nanoparticles as UV filters and delivery systems. The work's second split discusses the safety and legal implications of nanoparticles employed in compositions. Concluding remarks and suggestions for further study round out the work and enable material scientists to securely utilize nanoparticles in large-scale commercial goods.

Green Synthesis and Applications of Nanoparticles in Biomedical Chemistry

AbstractNumerous case studies have shown that nanoparticles (NPs) can help address raw material challenges in biomedical as well as healthcare‐related fields. The NPs derived from metal as well as metal oxide have exhibited remarkable therapeutic potential in clinical research. The strategies for nanomaterials interaction with cells can be employed to demonstrate their significance as well as enhance their optimistic potential in the health as well as medical domain. There have been numerous scientific initiatives to discuss antibiotic resistance as well as the antibacterial properties of metal‐based NPs. Regardless of such advancements; there is still a need to investigate their achievement to address current challenges in this field. Thus, this review looks into the contributions of various types of nanoparticles, as well as potential biological and biomedical applications. According to recent advancements as well as applications, metal oxide, and metal‐based NPs are predicted to play a significant part in the healthcare system. The opportunities, as well as challenges for NP commercial advancement, are linked to improving production with optimized scenarios.

Techniques and Instruments for Assessing and Reducing Risk of Exposure to Nanomaterials in Construction, Focusing on Fire-Resistant Insulation Panels Containing Nanoclay.

The paper explains how nano exposure is assessed in the construction field and focuses on the production of fire-resistant insulation panels with nanoclay. Utilizing the commercial ANSYS CFX® software, a preliminary theoretical simulation was conducted on nano exposure in the workplace, which revealed that particle dispersion is primarily driven by diffusion. Panel post-processing through drilling results in the highest inhalation exposure, followed by mixing and grinding activities. Compared to a state of 'no activity', each activity resulted in an exposure increase by a factor of min. 1000. An overall assessment suggests that the use of nanoparticles in construction materials may not significantly heighten workers' exposure to nanopowders when considering particle concentration alone as opposed to using traditional micro-scale materials. However, the issue persists when it comes to blending powders or performing finishing tasks on panels, with concentration levels being significantly higher for drilling, grinding, and mixing powders at 2.4 times above the standard reference value (40,000 particles/cm3); this is unacceptable, even for brief durations. Examination of dermal contact with gloves and masks worn by workers revealed no nanoparticle penetration. Safety measures were proposed for workers based on decision trees to enhance their safety. Ten categories of protection strategies have been devised to combat the impact of nanoparticles, which are tailored to specific technical situations, but they must be modified for various types of nanoparticles despite potential shared health implications.

K-means clustering optimization of various quantum dots and nanoparticles-added biofuels for engine performance, emission, vibration, and noise characteristics

The utilization of biodiesel as a bio-lubricant, combined with various types of nanoparticles, and quantum dots presents an innovative approach towards enhancing the performance of diesel engines. In this study, biodiesel was blended with different nanoparticles to improve its lubricating properties, and the k-means clustering method was applied to identify the optimal nanoparticle that maximizes the performance of the diesel engine. The experiment involved synthesizing biodiesel-based lubricants infused with nanoparticles of varying compositions, including but not limited to carbon nanotubes, graphene oxide, and metal oxides. The successful implementation of the Entropy-k-means hybrid model facilitated the identification of the optimal bio-lubricant for diesel engines. The experimentation uncertainty came out to be 4 % which lies in an acceptable range. Additionally, a strong Pearson r correlation was observed between Brake Thermal Efficiency (BTE) and Sound, highlighting their interrelationship. Moreover, the prioritization analysis indicated that NOx obtained the highest priority at 0.45, contrasting with the lowest priority attributed to sound at 0.01. Furthermore, the clustering analysis conclusively identified magnetic bio-lubricant as the top-performing option with minimum centroidal distance of 1.2. The optimal outcomes are BTE (30.5 %), Brake Specific Fuel Consumption (191.5 g/kWh), NOx (88 ppm), CO (7.1 g/km), Vibration (68.5 Hz), and Sound (74.5 dB). The application of k-means clustering facilitated the identification of the most effective nanoparticle for enhancing engine performance, thereby contributing to the advancement of sustainable lubrication technologies in the automotive industry.

Comprehensive Review of Recent Advances in Nanoparticle-Based Corrosion Inhibition Approaches

Corrosion of metals is a persistent challenge in various industries, leading to significant economic losses and safety hazards. Conventional corrosion inhibitors often face limitations such as environmental toxicity, low efficiency, and short-term protection. Nanoparticle-based corrosion inhibitors have emerged as a promising alternative due to their unique properties and versatile applications. This paper provides a comprehensive review of the recent advances in nanoparticle-based corrosion inhibition strategies from 2015-2024 by harvesting data from secondary sources. The fundamental mechanisms underlying the corrosion inhibition by nanoparticles are discussed, including adsorption processes, passivation mechanisms, and synergistic effects with other inhibitors. Various types of nanoparticles, including metallic nanoparticles, metal oxide nanoparticles, polymer nanocomposites, carbon-based nanoparticles, and organic-inorganic hybrid nanoparticles, are explored for their corrosion inhibition potential. Furthermore, the applications of nanoparticle-based corrosion inhibitors in industries such as oil and gas, aerospace, automotive, marine, and infrastructure are highlighted. Despite significant progress, challenges such as stability, compatibility, and environmental concerns remain to be addressed. Future directions in nanoparticle-based corrosion inhibition research are also discussed, aiming to guide further developments in this promising field.

Inhaled Nanoparticulate Systems: Composition, Manufacture and Aerosol Delivery.

An increasing growth in nanotechnology is evident from the growing number of products approved in the past decade. Nanotechnology can be used in the effective treatment of several pulmonary diseases by developing therapies that are delivered in a targeted manner to select lung regions based on the disease state. Acute or chronic pulmonary disorders can benefit from this type of therapy, including respiratory distress syndrome (RDS), chronic obstructive pulmonary disease (COPD), asthma, pulmonary infections (e.g. tuberculosis, Yersinia pestis infection, fungal infections, bacterial infections, and viral infections), lung cancer, cystic fibrosis (CF), pulmonary fibrosis, and pulmonary arterial hypertension. Modification of size and surface property renders nanoparticles to be targeted to specific sites, which can serve a vital role in innovative pulmonary drug delivery. The nanocarrier type chosen depends on the intended purpose of the formulation and intended physiological target. Liquid nanocarriers and solid-state nanocarriers can carry hydrophilic and hydrophobic drugs (e.g. small molecular weight drug molecules, large molecular weight drugs, peptide drugs, and macromolecular biological drugs), while surface modification with polymer can provide cellular targeting, controlled drug release, and/or evasion of phagocytosis by immune cells, depending on the polymer type. Polymeric nanocarriers have versatile architectures, such as linear, branched, and dendritic forms. In addition to the colloidal dispersion liquid state, the various types of nanoparticles can be formulated into the solid state, offering important unique advantages in formulation versatility and enhanced stability of the final product. This chapter describes the different types of nanocarriers, types of inhalation aerosol device platforms, liquid aerosols, respirable powders, and particle engineering design technologies for inhalation aerosols.

Solid‐State Processing of Nascent Disentangled UHMWPE Reactor Powders Mixed with Carbon Nanoparticles

AbstractAspects of solid‐state processing of nascent disentangled ultra‐high‐molecular‐weight polyethylene (UHMWPE) powders of different syntheses mixed with electrically conductive carbon nanoparticles (NPs) of various types are studied. Effect of multiple parameters of the processing procedures on the electrophysical characteristics of the composite samples is investigated. Such parameters include time of preliminary ultrasonication (US) of NPs, time of US of UHMWPE/NPs mixtures, molding time, temperature, and pressure, deformation degree, etc. It is observed that by selecting optimal values of such parameters it is possible to obtain samples of composites with an extremely segregated structure made of the NPs, with NPs distributed evenly on the surfaces of the compacted UHMWPE powder particles. This ensures high levels of conductivity at very low values of NPs content. The segregated structure is retained when the composites are strengthened using the solid‐state uniaxial shear deformation process. While conductivity of most of the composites filled with various types of NPs monotonously decreases with the deformation ratio, conductivity of the composites filled with exceptionally long double‐walled carbon nanotubes is maintained. The processed oriented composites are also characterized by high EMR shielding properties, as well as interesting temperature dependencies of the electrical conductivity.

Flotation Coefficient Distributions of Lipid Nanoparticles by Sedimentation Velocity Analytical Ultracentrifugation.

The robust characterization of lipid nanoparticles (LNPs) encapsulating therapeutics or vaccines is an important and multifaceted translational problem. Sedimentation velocity analytical ultracentrifugation (SV-AUC) has proven to be a powerful approach in the characterization of size-distribution, interactions, and composition of various types of nanoparticles across a large size range, including metal nanoparticles (NPs), polymeric NPs, and also nucleic acid loaded viral capsids. Similar potential of SV-AUC can be expected for the characterization of LNPs, but is hindered by the flotation of LNPs being incompatible with common sedimentation analysis models. To address this gap, we developed a high-resolution, diffusion-deconvoluted sedimentation/flotation distribution analysis approach analogous to the most widely used sedimentation analysis model c(s). The approach takes advantage of independent measurements of the average particle size or diffusion coefficient, which can be conveniently determined, for example, by dynamic light scattering (DLS). We demonstrate the application to an experimental model of extruded liposomes as well as a commercial LNP product and discuss experimental potential and limitations of SV-AUC. The method is implemented analogously to the sedimentation models in the free, widely used SEDFIT software.

An Overview of Nanoparticle-Based Delivery Platforms for mRNA Vaccines for Treating Cancer.

With its unique properties and potential applications, nanoparticle-based delivery platforms for messenger RNA (mRNA) vaccines have gained significant attention in recent years. Nanoparticles have the advantages of enhancing immunogenicity, targeting delivery, and improving stability, providing a new solution for drug and vaccine delivery. In some clinical studies, a variety of nanoparticle delivery platforms have been gradually applied to a wide range of vaccine applications. Current research priorities are exploring various types of nanoparticles as vaccine delivery systems to enhance vaccine stability and immunogenicity. Lipid nanoparticles (LNPs) have shown promising potential in preclinical and clinical studies on the efficient delivery of antigens to immune cells. Moreover, lipid nanoparticles and other nanoparticles for nucleic acids, especially for mRNA delivery systems, have shown vast potential for vaccine development. In this review, we present various vaccine platforms with an emphasis on nanoparticles as mRNA vaccine delivery vehicles. We describe several novel nanoparticle delivery platforms for mRNA vaccines, such as lipid-, polymer-, and protein-based nanoparticles. In addition, we provide an overview of the anti-tumor immunity of nanovaccines against different tumors in cancer immunotherapy. Finally, we outline future perspectives and remaining challenges for this promising technology of nanoparticle-based delivery platforms for vaccines.

Ferroptosis resistance in cancer cells: nanoparticles for combination therapy as a solution.

Ferroptosis is a form of regulated cell death (RCD) characterized by iron-dependent lipid peroxidation. Ferroptosis is currently proposed as one of the most promising means of combating tumor resistance. Nevertheless, the problem of ferroptosis resistance in certain cancer cells has been identified. This review first, investigates the mechanisms of ferroptosis induction in cancer cells. Next, the problem of cancer cell resistance to ferroptosis, as well as the underlying mechanisms is discussed. Recently discovered ferroptosis-suppressing biomarkers have been described. The various types of nanoparticles that can induce ferroptosis are also discussed. Given the ability of nanoparticles to combine multiple agents, this review proposes nanoparticle-based ferroptosis cell death as a viable method of circumventing this resistance. This review suggests combining ferroptosis with other forms of cell death, such as apoptosis, cuproptosis and autophagy. It also suggests combining ferroptosis with immunotherapy.

Nanoparticles for the treatment of spinal cord injury.

Spinal cord injuries lead to significant loss of motor, sensory, and autonomic functions, presenting major challenges in neural regeneration. Achieving effective therapeutic concentrations at injury sites has been a slow process, partly due to the difficulty of delivering drugs effectively. Nanoparticles, with their targeted delivery capabilities, biocompatibility, and enhanced bioavailability over conventional drugs, are garnering attention for spinal cord injury treatment. This review explores the current mechanisms and shortcomings of existing treatments, highlighting the benefits and progress of nanoparticle-based approaches. We detail nanoparticle delivery methods for spinal cord injury, including local and intravenous injections, oral delivery, and biomaterial-assisted implantation, alongside strategies such as drug loading and surface modification. The discussion extends to how nanoparticles aid in reducing oxidative stress, dampening inflammation, fostering neural regeneration, and promoting angiogenesis. We summarize the use of various types of nanoparticles for treating spinal cord injuries, including metallic, polymeric, protein-based, inorganic non-metallic, and lipid nanoparticles. We also discuss the challenges faced, such as biosafety, effectiveness in humans, precise dosage control, standardization of production and characterization, immune responses, and targeted delivery in vivo. Additionally, we explore future directions, such as improving biosafety, standardizing manufacturing and characterization processes, and advancing human trials. Nanoparticles have shown considerable progress in targeted delivery and enhancing treatment efficacy for spinal cord injuries, presenting significant potential for clinical use and drug development.

Exploring dielectric properties and polarization relaxation processes in ionic liquid crystals with synthesized carbon and gold nanoparticles

The main goal is to study the structural and dielectric characteristics of advanced composite materials based on ionic metal alkanoates with various types of nanoparticles. The matrix Cd+2(C7H15COO)−2 formed as a result of the reaction of cadmium with the carboxylate groups of alkanoate (C7H15COO)−2 is used for the synthesis of nanoparticles. At room temperature, the matrix of the ionic crystalline material represents multilayer structure with each layer thickness of 1.8 nm. However, when heated in the temperature range from 100 °C to 180 °C, the matrix undergoes a phase transition into the liquid crystalline smectic A phase, preserved after cooling to room temperature. This transition opens up possibilities for the synthesis of carbon and gold nanoparticles. The temperature treatments of the matrix allow to control of the size and shape of nanoparticles during synthesis and create highly stable nanocomposites. The structural features and dielectric properties of these nanocomposites are studied using transmission electron microscopy, enabling to determine of the sizes of nanoparticles and their dispersion and impedance spectroscopy, respectively. Dielectric properties of nanocomposite materials were studied at different temperatures corresponding to two material phases. We carried out an analysis of the dielectric characteristics of the pure matrix in comparison with nanocomposite materials, containing carbon and gold nanoparticles to identify the role of the nanoparticles. Based on our experimental data, we proposed a model to explain the charge transfer process, taking into account relaxation processes and polarization of nanocomposite materials.

Development and Characterization Pioglitazone Hydrochloride Loaded Nanoparticle for Management of Diabetes Mellitus

The potential applications of nanoparticles as oral drug delivery systems for diabetes treatment are discussed in this research article. This paper discusses polymeric nanoparticles, polysaccharides, and polymeric nanoparticles in the oral administration of anti-diabetic drugs. Diabetes is a chronic metabolic disorder characterized by insulin deficiency. Diabetes treatments are numerous, and nanoparticles have several advantages. Several studies and research reports based on nanotechnological approaches in the formulation of anti-diabetic drugs have highlighted the fact that research in the formulation of nanodrugs improved diabetes-fighting strategies based on plausible molecular mechanisms of action of the drugs. Additionally, efforts have been made to determine the optimal drug concentration and time of exposure in order to recommend a scientifically validated drug dose response in the development of various therapeutic strategies for anti-diabetic drugs, various types of nanoparticles are available; polymeric nanoparticles are one of the most commonly used nanoparticles. Polymeric nanoparticles range in size from 10-1000 nm. Polymeric nanoparticles created by combining a drug and a polymer. The main advantages of polymeric nanoparticles are their ease of preparation, targeted delivery, dose minimization, and high therapeutic efficiency.

Volatile carbonyl metabolites analysis of nanoparticle exposed lung cells in an organ-on-a-chip system

The evaluation of nanoparticles (NPs) cytotoxicity is crucial for advancing nanotechnology and assessing environmental pollution. However, existing methods for NPs cytotoxicity evaluation suffer from limited accuracy and inadequate information content. In the study, we developed a novel detection platform that enables the identification of cellular carbonyl metabolites at the organ level. The platform is integrated with a cell co-culture lung organ chip (LOC) and a micropillar concentrator. Notably, our work represents the successful measurement of the amounts of cellular metabolites on LOC system. The volatile carbonyl metabolites (VCMs) generated by cells exposure to various types of NPs with different concentrations were captured and detected by high-resolution mass spectrometry (MS). Compared with conventional cell viability and reactive oxygen species (ROS) analysis, our method discerns the toxicological impact of NPs at low concentrations by analyzed VCM at levels as low as ppb level. The LOC system based metabolic gas detection confirmed that low concentrations of NPs have a toxic effect on the cell model, which was not reflected in the fluorescence detection, and the effect of NP material is more significant than the size effect. Furthermore, this method can distinguish different NPs acting on cell models through cluster analysis of multiple VCMs.

Different therapeutic approaches in melasma: advances and limitations.

Melasma is a chronic hyperpigmentation skin disorder that is more common in the female gender. Although melasma is a multifactorial skin disorder, however, sun-exposure and genetic predisposition are considered as the main etiologic factors in melasma occurrence. Although numerous topical and systemic therapeutic agents and also non-pharmacologic procedural treatments have been considered in melasma management, however, the commonly available therapeutic options have several limitations including the lack of sufficient clinical effectiveness, risk of relapse, and high rate of unwanted adverse drug reactions. Recruitment of nanotechnology for topical drug delivery in melasma management can lead to enhanced skin penetration, targeted drug delivery to the site of action, longer deposition at the targeted area, and limit systemic absorption and therefore systemic availability and adverse drug reactions. In the current review, first of all, the etiology, pathophysiology, and severity classification of melasma have been considered. Then, various pharmacologic and procedural therapeutic options in melasma treatment have been discussed. Afterward, the usage of various types of nanoparticles for the purpose of topical drug delivery for melasma management was considered. In the end, numerous clinical studies and controlled clinical trials on the assessment of the effectiveness of these novel topical formulations in melasma management are summarized.

Evaluation of Antidiabetic Activity and Cytotoxic Effect of Strontium Nanoparticles Synthesized Using Mimosa Pudica.

Nanotechnology is emerging as a promising approach in the development of novel therapeutic strategies. Nanoparticles, due to their unique physicochemical properties and small size, have the potential to improve the delivery of therapeutic agents, enhance their bioavailability, and increase their efficacy. Among various types of nanoparticles, strontium nanoparticles have gained attention due to their potential antidiabetic activity and cytotoxic effects against cancer cells. Mimosa pudica, also known as "Sensitive Plant" or "Touch-Me-Not," is a medicinal plant known for its diverse pharmacological activities, including antidiabetic and anticancer properties. Recent research has focused on the synthesis of strontium nanoparticles by using Mimosa pudica as a green and sustainable approach. These nanoparticles have shown promising results in terms of their antidiabetic activity and cytotoxic effects against cancer cells. Thus, in this study, the antidiabetic effect was studied using the alpha-amylase inhibitor assay, and the cytotoxic effect was studied using the brine shrimp lethality assay. In these assays, increasing concentration of Mimosa pudica-mediated strontium nanoparticles exhibited increasing antidiabetic and cytotoxic effects, which was similar to the standard used, which is acarbose. Hence, this can be used as a novel antidiabetic and cytotoxic agent in the future.

The Impact of Nanomaterials on Photosynthesis and Antioxidant Mechanisms in Gramineae Plants: Research Progress and Future Prospects.

As global food security faces challenges, enhancing crop yield and stress resistance becomes imperative. This study comprehensively explores the impact of nanomaterials (NMs) on Gramineae plants, with a focus on the effects of various types of nanoparticles, such as iron-based, titanium-containing, zinc, and copper nanoparticles, on plant photosynthesis, chlorophyll content, and antioxidant enzyme activity. We found that the effects of nanoparticles largely depend on their chemical properties, particle size, concentration, and the species and developmental stage of the plant. Under appropriate conditions, specific NMs can promote the root development of Gramineae plants, enhance photosynthesis, and increase chlorophyll content. Notably, iron-based and titanium-containing nanoparticles show significant effects in promoting chlorophyll synthesis and plant growth. However, the impact of nanoparticles on oxidative stress is complex. Under certain conditions, nanoparticles can enhance plants' antioxidant enzyme activity, improving their ability to withstand environmental stresses; excessive or inappropriate NMs may cause oxidative stress, affecting plant growth and development. Copper nanoparticles, in particular, exhibit this dual nature, being beneficial at low concentrations but potentially harmful at high concentrations. This study provides a theoretical basis for the future development of nanofertilizers aimed at precisely targeting Gramineae plants to enhance their antioxidant stress capacity and improve photosynthesis efficiency. We emphasize the importance of balancing the agricultural advantages of nanotechnology with environmental safety in practical applications. Future research should focus on a deeper understanding of the interaction mechanisms between more NMs and plants and explore strategies to reduce potential environmental impacts to ensure the health and sustainability of the ecosystem while enhancing the yield and quality of Gramineae crops.