The Northern Alpine Foreland Basin (i.e., Molasse Basin) developed due to flexural subsidence from slab- and topographic loading during continental collision between the Adriatic and European plates. Previous studies highlight a diachronous transition from underfilled- to overfilled conditions in the Molasse Basin in response to orogen-parallel variations in flexural subsidence and sediment supply. In this contribution, we investigate the lithospheric- and crustal-scale orogenic process(es) that generated this diachronous transition. For this, we conducted a tectonostratigraphic analysis of the Molasse Basin. Firstly, we constructed a 3D geological model to derive the architecture of the European margin during the Eocene onset of flexure. Second, 2D/3D reflection seismic- and borehole data were used to characterise the spatiotemporal development of depositional environments and syn-flexural normal fault kinematics in the German Molasse. Our data show a stepwise rather than continuous eastward migration of the underfilled- to overfilled transition. Furthermore, syn-flexural fault kinematics document a Rupelian to early Burdigalian northward younging trend and higher cumulative Cenozoic offsets in the Eastern German Molasse (< 230 m) compared to the Western German Molasse (< 150 m). This implies a west-to-east increase in the curvature of bending of the European plate, induced by along-strike variations in the magnitude of applied loads and/or European lithospheric strength variations. These variations drove lateral variations in accommodation space and sediment supply. Subsequently, this led to the diachronous underfill-to-overfilled transition in the Molasse Basin. Taken together, we suggest that the diachronous transition was driven by spatiotemporal variations in the thickening of the orogenic wedge supported by slab detachment, promoted by subduction- and collision of the irregular European margin.
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