Short production runs are common in industries that require high flexibility and variety in manufacturing. Only a limited amount of researches on multivariate control charts in short production runs exists in the literature. This article proposes two one-sided adaptive charts for monitoring the multivariate coefficient of variation (MCV) in short production runs by varying the sample size (called the VSS MCV SPR charts). The two one-sided adaptive charts are the upper-sided and lower-sided VSS MCV SPR charts for monitoring increasing and decreasing shifts, respectively, in the process MCV. The optimal parameters of the VSS MCV SPR charts in minimizing the out-of-control truncated average run length (TARL) value, for various shift sizes, are presented. The proposed VSS MCV SPR charts outperform their non-adaptive short production runs Shewhart MCV counterparts (called the SH MCV SPR charts), as the former have smaller out-of-control TARL value than the latter, for the same shift size. The sensitivity of the VSS MCV SPR charts, in terms of the probability of signaling an alarm within I inspections is also studied, where the VSS MCV SPR charts surpass their corresponding SH MCV SPR charts. An example for implementing the VSS MCV SPR charts is provided.