Response Variables Research Articles

Erythropoiesis-stimulating agent responsiveness and hemoglobin variability is associated with fat tissue index in hemodialysis patients with darbepoetin-alfa treatment: a prospective observational cohort study

Erythropoiesis-stimulating agent responsiveness and hemoglobin variability is associated with fat tissue index in hemodialysis patients with darbepoetin-alfa treatment: a prospective observational cohort study

Ethnic bias and the hidden curriculum: The impact of routine inclusion of ethnicity in medical education assessment

Introduction: In 2012, the University of Otago Medical School in New Zealand amended high stakes examination questions to routinely include ethnicity. This policy change was prompted by the assessment committee, including the Māori subcommittee. This study aimed to examine the portrayal of Māori patients and to explore the impact of routine inclusion of ethnicity. Methods: A quantitative description of demographic variables of examination questions and responses (role-model answers, multiple-response preferred answer, guidelines for markers) from a pre policy (2009–2011), post policy (2012–2013) and follow-up period (2018–2019) was undertaken. A qualitative content analysis of Māori examination questions was conducted with consideration of trends over time. Results: The majority (98%) of examination questions did not report ethnicity prior to the 2012 policy, whereas around 80% of cases did post policy implementation. Three themes were identified: the non-adherent Māori patient, determinants of health and the patient assigned Māori ethnicity. Examination questions and responses that portrayed Māori as being non-adherent were more common prior to the implementation of the policy. Post policy, many questions did not require students to consider the relevance of ethnicity but presented an increase in social and cultural contextual information of the patient over time. Conclusion: Policy implementation by the assessment committee led to less racist stereotyping and “othering” of Māori patients and prompted further refinement of social and cultural determinants of health over time. Future recommendations include increasing representation of Māori as a reflection of the increased burden of disease alongside representing intersectionality using other socio-cultural indicators.

ANALISIS TINGKAT KEPUASAN MASYARAKAT TERHADAP PELAYANAN PADA KANTOR IMIGRASI KELAS I KHUSUS TPI NGURAH RAI

This research was conducted to analyze the level of public satisfaction with services at the TPI Ngurah Rai Special Class I Immigration Office, which was motivated by the high number of complaints and requests for information as well as the lowest rating from Google reviews among other immigration offices in Bali. The results of previous research show varying results regarding the influence of tangible, reliability, responsiveness, assurance and empathy aspects on community satisfaction. The aim of this research is to determine the effect of service quality using ServQual (tangible, reliability, responsiveness, assurance and empathy) on community satisfaction at the TPI Ngurah Rai Special Class I Immigration Office partially and simultaneously. This research uses descriptive quantitative methods. The total sample was 100 respondents with sampling using the accidental sampling method. The data analysis technique uses multiple linear regression analysis with hypothesis testing using the t test and F test. The results simultaneously show that the variables tangible, reliability, responsiveness, assurance and empathy have a significant effect on community satisfaction. Partial results show that the tangible and assurance variables do not have a significant effect on community satisfaction, the empathy variable has a negative but not significant effect on community satisfaction, and the reliability and responsiveness variables have a significant influence on community satisfaction. The determination test showed that 62.9% of the variation in community satisfaction variables could be influenced by tangible, reliability, responsiveness, assurance and empathy variables.

Kepuasan Pelanggan pada Kualitas Layanan Bengkel Amien Jaya Motor Bangkalan

The aim of the study was to determine the effect of the dimensions of service quality which include tangibles, reliability, responsiveness, assurance and empathy on customer satisfaction at the Amien Jaya Motor workshop. This study used a quantitative method with a survey research type. This research was conducted at the Amien Jaya Motor Workshop involving 97 people or a questionnaire. Based on the results of the t test on tangible variables it has a significant effect on customer satisfaction while the t test on the reliability variable has a significant effect on customer satisfaction for the t test on the responsiveness variable also has a significant effect on customer satisfaction. In the t-test, the assurance variable has a significant effect on customer satisfaction, while in the t-test, the empathy variable also has a significant effect on customer satisfaction. Based on the results of the elaboration above, the quality of service which includes (Tangibles, Reliability, Responsiveness, Assurance, and Emphaty has a positive and significant simultaneous effect on customer satisfaction at Amien Jaya Motor (AJM) workshops). This can be proven by the results of the partial test (t test) the result shows that the f-count value is greater than the f- table so that it can be concluded that service quality affects customer satisfaction.

Impacts of Acute Psychological Stress on the Emotions of Individuals with Early Life Stress.

The study aimed to evaluate negative and positive emotional responses to acute psychological stress in individuals with early life stress (ELS). One hundred sixty-one participants from the Birmingham community in Alabama completed the study and were stratified into 2 groups based on measurements of ELS using the Childhood Trauma Questionnaire and a confirmatory clinical interview. Acute psychological stress, that is, the Trier Social Stress Test (TSST), was administered, and emotional responses were measured using the Visual Analogue Scale. Comparisons utilized chi-square for categorical variables and t-test for continuous variables. Analysis of covariance (ANCOVA) was applied to compare the 2 groups after controlling for confounding variables. Stepwise multiple linear regression analysis was used to investigate predictive power of variables for emotional responses to the TSST. Participants with ELS experienced less pleasantness at the baseline (P = .02), and 1 minute (P = .04), but not 90 minutes time points compared to the non-ELS group. Participants in the ELS group also reported higher anxiety at baseline (P = .003), and 90 minutes (P = .04) post-TSST. Data analysis showed the effect of time on emotional responses during the TSST. Different emotional responses, including pleasantness, anxiety, fatigue, and vigor, were able to be predicted by ELS severity. Our data demonstrates that individuals with ELS presented different positive and negative emotional responses when exposed to acute psychological stress. Our findings may be useful for clinicians who work with individuals with ELS. Our findings also highlight the importance of recognizing emotional responses and of building up resilience in response to acute stress.

Analysis of Service Effectiveness on Customer Satisfaction in the Food & Beverage Bussiness in Tarutung, North Tapanuli - North Sumatra

The aim of this research is to determine the impact of service towards the consumer satisfaction, and the use of digital technology in service operations in the food and beverage business in Tarutung, North Tapanuli. The data processing techniques were obtained through distributing questionnaires to 80 respondents. The data analysis technique used is simple regression analysis. The research shows that a). physical appearance variables have a significant negative effect on consumer satisfaction; the reliability variable has an insignificant positive effect on consumer satisfaction; the responsiveness variable has a negative/insignificant effect on consumer satisfaction; the concern variable has a negative/insignificant effect on consumer satisfaction; and the guarantee variable has a significant effect on consumer satisfaction. The variables that have a dominant influence are the physical appearance variable and the guarantee variable which has a significant influence on consumer satisfaction. This means that service effectiveness (reliability, response has a positive and significant effect on consumer or customer satisfaction in the food and beverage business "is proven empirically and is acceptable, b) the use of technology in food and beverage café and restaurant services in Tarutung City still tends to be limited and low

Strategy To Increase Customer Satisfaction Based On Service Quality

The purpose of this research is to determine and analyze how the affect of service quality (reliability, responsiveness, assurance, empathy, tangible) simultaneously and partially on customer satisfaction, customer satisfaction level index, and implementation and performance strategies of PT Jayamandiri Gemasejati Bogor. This research uses quantitative data and primary data types through distributing questionnaires using a Likert scale. The sample in this research distributrd to 100 people with non-probability sampling technique, namely accidental sampling. The method used in this research is multiple linear regression analysis. The results showed that in the simultaneous test results (f test) it was found that the independent variables of reliability, assurance, empathy, responsiveness, and Tangible simultaneously had a positive and significant affect on customer satisfaction and for the partial test results (t test) it is found that the variables of reliability, responsiveness, and assurance have a positive and significant affect on customer satisfaction, respectively At the same time, the variables of empathy and tangible partially are not having a positive and significant affect on customer satisfaction.. The result of the Customer Satisfaction Index (CSI) score of service quality is 68.25%. The implementation strategy uses important performance analysis (IPA), the strategy is a) Make continuous improvements so that performance attributes increase b) Maintaining so that the performance does not decrease c) This quadrant must be seriously managed because it usually causes customer disappointment d) Evaluate all excessive activities.

Metaplastic neuromodulation via transcranial direct current stimulation has no effect on corticospinal excitability and neuromuscular fatigue

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation tool with potential for managing neuromuscular fatigue, possibly due to alterations in corticospinal excitability. However, inconsistencies in intra- and inter- individual variability responsiveness to tDCS limit its clinical use. Emerging evidence suggests harnessing homeostatic metaplasticity induced via tDCS may reduce variability and boost its outcomes, yet little is known regarding its influence on neuromuscular fatigue in healthy adults. We explored whether cathodal tDCS (ctDCS) prior to exercise combined with anodal tDCS (atDCS) could augment corticospinal excitability and attenuate neuromuscular fatigue. 15 young healthy adults (6 males, 22 ± 4 years) participated in four pseudo-randomised neuromodulation sessions: sham stimulation prior and during exercise, sham stimulation prior and atDCS during exercise, ctDCS prior and atDCS during exercise, ctDCS prior and sham stimulation during exercise. The exercise constituted an intermittent maximal voluntary contraction (MVC) of the right first dorsal interosseous (FDI) for 10 min. Neuromuscular fatigue was quantified as an attenuation in MVC force, while motor evoked potential (MEP) amplitude provided an assessment of corticospinal excitability. MEP amplitude increased during the fatiguing exercise, whilst across time, force decreased. There were no differences in MEP amplitudes or force between neuromodulation sessions. These outcomes highlight the ambiguity of harnessing metaplasticity to ameliorate neuromuscular fatigue in young healthy individuals.

The assessment of therapist responsiveness in psychotherapy research: a systematic review.

Therapist responsiveness is an emerging construct in psychotherapy research that still lacks a clear definition and, consequently, a unique operationalization. Indeed, there is a great overlap between therapist responsiveness and other variables, such as attunement, flexibility, and empathy. This overlap inevitably hinders the assessment of the therapist's responsiveness, although it is crucial for the effectiveness of the treatments. Therefore, the current systematic review aims at exploring the different methodologies of measurement and analysis of therapist responsiveness, including both direct and indirect instruments. The results confirmed difficulties and divergences in the operationalization of the construct, as shown by the great heterogeneity found in the choice and use of the tools. Furthermore, this review provides guidance for future research, clinical practice, and training of therapists.

Analisis Kualitas Sistem SLIMS Terhadap Kepuasan Mahasiswa Dengan Metode E-Servqual dan Importance Performance Analysis

SLIMS at the XYZ University library has been built since 2014 and began to be implemented in 2018 and has been running until now. During implementation there were several problems, including incomplete book collections, this caused students to prefer choosing books manually. Apart from that, sometimes there are still some problems that occur when processing the data used. Many users still don't understand how to use SLIMS. This research aims to measure the level of user satisfaction and provide suggestions for improving the SLIMS system. The method used in this research is E-Servqual which has 5 variables in this method and the Importance Performance Analysis method is used to compare user assessments of the level of importance of service quality. The data obtained from this research was distributing questionnaires to a sample of 100 respondents. Data processing was carried out using the SMART-PLS 4 tool. The analysis results obtained for the level of user satisfaction were 3 variables that were significant and influenced user satisfaction, namely the Empathy, Responsiveness and Tangible variables. Meanwhile, the other 2 variables, namely Assurance and Reliability, do not have a significant relationship with user satisfaction. This shows that students are still quite satisfied and a science analysis was carried out on 4 quadrants to evaluate service factor based on the level of user satisfaction

Pengaruh Kualitas Pelayanan terhadap Kepuasan Pelanggan di Hotel Pyramid Suites Banjarmasin

Banjarmasin is a unique city nicknamed the City of a Thousand Rivers. This uniqueness is what causes many entrepreneurs to come to open businesses, one of which is a hotel business. The recommended hotel in Banjarmasin is the Pyramid Suites Hotel. Because apart from having good quality products and services, this hotel has also received many awards from various online hotel booking applications. Therefore, researchers are interested in further researching the Pyramid Suites hotel in Banjarmasin with the aim of analysing the influence of service quality on guest customer satisfaction at the Pyramid Suites Banjarmasin hotel. This study aims to analyse and describe how much influence service quality has on customer satisfaction. This type of research is quantitative, with a conclusive causal approach, namely research that aims to obtain a conclusion from the data that has been obtained and processed which explains the causal relationship between the variables. The population in this study are members of Hotel Pyramid Suites, namely guests who stay more than three times. research sample as many as 100 respondents. The data collection technique used a questionnaire which was then used as a score tabulation for each variable studied. The data analysis method used in this study is Smart PLS 3. The results showed that the quality of service which consists of variables of physical evidence, reliability, responsiveness, assurance and empathy affect customer satisfaction.

Pengaruh Kualitas Sumber Daya Manusia dan Budaya Organisasi terhadap Responsivitas Pelayanan Pegawai Badan Pendapatan Daerah Provinsi Sumatera Utara

The aim of this research is to determine and analyze the influence of HR quality on the service responsiveness of North Sumatra Province Regional Revenue Agency employees, to determine and analyze the influence of organizational culture on the service responsiveness of North Sumatra Province Regional Revenue Agency employees, to determine and analyze the influence of HR quality and organizational culture towards service responsiveness of North Sumatra Province Regional Revenue Agency employees. The population in this study were all employees of the Regional Revenue Agency of North Sumatra Province, namely 176 employees and sampling was carried out using total sampling so that 64 respondents were used as samples. Based on the research results, it is known that there is a positive influence of the HR quality variable on the Service Responsiveness variable, thus partially there is a significant influence between the quality of human resources on employee service responsiveness, there is a positive influence of the Organizational Culture variable on the Service Responsiveness variable) thus partially there is a significant influence between Organizational Culture on employee Service Responsiveness. The quality of human resources and organizational culture influence service responsiveness. Thus, there is a positive and significant influence on the quality of human resources and organizational culture on employee service responsiveness

Random Responses of Shield Tunnel to New Tunnel Undercrossing Considering Spatial Variability of Soil Elastic Modulus

This paper investigates the effect of spatial variability of soil elastic modulus on the longitudinal responses of the existing shield tunnel to the new tunnel undercrossing using a random two-stage analysis method (RTSAM). The Timoshenko–Winkler-based deterministic method considering longitudinal variation in the subgrade reaction coefficient and the random field of the soil elastic modulus discretized by the Karhunen–Loeve expansion method are combined to establish the RTSAM. Then, the proposed RTSAM is applied to carry out a random analysis based on an actual engineering case. Results show that the increases in the scale of fluctuation and the coefficient of variation of the soil elastic modulus lead to higher variabilities of tunnel responses. A decreasing pillar depth and mean value of the soil elastic modulus and an increasing skew angle strengthen the effect of the spatial variability of the soil elastic modulus on tunnel responses. The variabilities of tunnel responses under the random field of the soil elastic modulus are overestimated by the Euler–Bernoulli beam model. The results of this study provide references for the uncertainty analysis of the new tunneling-induced responses of the existing tunnel under the random field of soil properties.

Neural populations within macaque early vestibular pathways are adapted to encode natural self-motion.

How the activities of large neural populations are integrated in the brain to ensure accurate perception and behavior remains a central problem in systems neuroscience. Here, we investigated population coding of naturalistic self-motion by neurons within early vestibular pathways in rhesus macaques (Macacca mulatta). While vestibular neurons displayed similar dynamic tuning to self-motion, inspection of their spike trains revealed significant heterogeneity. Further analysis revealed that, during natural but not artificial stimulation, heterogeneity resulted primarily from variability across neurons as opposed to trial-to-trial variability. Interestingly, vestibular neurons displayed different correlation structures during naturalistic and artificial self-motion. Specifically, while correlations due to the stimulus (i.e., signal correlations) did not differ, correlations between the trial-to-trial variabilities of neural responses (i.e., noise correlations) were instead significantly positive during naturalistic but not artificial stimulation. Using computational modeling, we show that positive noise correlations during naturalistic stimulation benefits information transmission by heterogeneous vestibular neural populations. Taken together, our results provide evidence that neurons within early vestibular pathways are adapted to the statistics of natural self-motion stimuli at the population level. We suggest that similar adaptations will be found in other systems and species.

Analisis Kualitas Layanan dan Kepuasan Konsumen Pengguna Jasa Rumah Sakit Islam Nashrul Ummah

This research wants to describe the influence of service quality and service user satisfaction at the Nashrul Ummah Islamic Hospital. The analytical method used is multiple regression analysis. Service quality variables include Reliability (X1), Responsiveness (X2), Confidence (X3), Empathy (X4) and Satisfaction variables (Y). Data collection was done by distributing numbers to 50 respondents as service users. The research results show that service quality consisting of Reliability (X1), Responsiveness (X2), Confidence (X3), Empathy (X4) has significant variables on Satisfaction (Y). This research also shows that the responsiveness variable is very dominant in its influence on satisfaction

Focus on current and emerging treatment options for glioma: A comprehensive review.

This comprehensive review delves into the current updates and challenges associated with the management of low-grade gliomas (LGG), the predominant primary tumors in the central nervous system. With a general incidence rate of 5.81 per 100000, gliomas pose a significant global concern, necessitating advancements in treatment techniques to reduce mortality and morbidity. This review places a particular focus on immunotherapies, discussing promising agents such as Zotiraciclib and Lerapolturev. Zotiraciclib, a CDK9 inhibitor, has demonstrated efficacy in glioblastoma treatment in preclinical and clinical studies, showing its potential as a therapeutic breakthrough. Lerapolturev, a viral immunotherapy, induces inflammation in glioblastoma and displays positive outcomes in both adult and pediatric patients. Exploration of immunotherapy extends to Pembrolizumab, Nivolumab, and Entrectinib, revealing the challenges and variabilities in patient responses. Despite promising preclinical data, the monoclonal antibody Depatuxizumab has proven ineffective in glioblastoma treatment, emphasizing the critical need to understand resistance mechanisms. The review also covers the success of radiation therapy in pediatric LGG, with evolving techniques, such as proton therapy, showing potential improvements in patient quality of life. Surgical treatment is discussed in the context of achieving a balance between preserving the patient's quality of life and attaining gross total resection, with the extent of surgical resection significantly influencing the survival outcomes. In addition to advancements in cancer vaccine development, this review highlights the evolving landscape of LGG treatment, emphasizing a shift toward personalized and targeted therapies. Ongoing research is essential for refining strategies and enhancing outcomes in the management of LGG.

Semi-Active Groundhook Control of Offshore Tension Leg Platforms Using Tuned Mass Damper With Optimized Parameters and Magneto-Rheological Damper Under Multiple Hazards

Abstract The purpose of the current study is to recommend an offshore tension leg platform (TLP) semi-active control system to lessen vibrations caused by various risks, such as the wind load and regular and irregular waves. State-of-the-art indicates that there has not been much study on semi-active management of offshore TLPs exposed to numerous hazards while taking into account system nonlinearities and employing a control method that is resilient to uncertainty. An augmented velocity–displacement-based groundhook (AVDB-GH) semi-active control scheme using magneto-rheological (MR) dampers, which is an improvement over the displacement-based groundhook (DB-GH) control algorithm, is proposed. The proposed controller uses a semi-active tuned mass damper (SATMD) consisting of a passive tuned mass damper (TMD) and two semi-active MR dampers as the control devices. Constrained nonlinear optimization is used to determine the SATMD's optimized parameters in order to produce the best control performance. A significant reduction in surge response of TLP is observed both in the time domain and the frequency domain. Compared to the SATMD using the usual DB-GH algorithm, the suggested control strategy more successfully decreases the key response variables—deck displacement, power spectral density, and acceleration. The effectiveness of the controller is better for regular waves than for irregular waves and wind forces. Because the performance of the controller is unaffected by changes in the mass and stiffness of the TLP, the controller can be regarded as robust.

Mengukur Indeks Kepuasan Mahasiswa Fakultas Ekonomi Universitas 45 Surabaya Terhadap Variabel Layanan Akademik

This research aims to determine the quality of service at the Faculty of Economics, University 45 Surabaya. The population used as subjects in this research was 300 students from the Faculty of Economics, University 45 Surabaya. Determining the sample in this study used probability sampling with proportional sample strata. The results of the analysis using the Importance Performance Analysis (IPA) method show that the services that occur are not running effectively. In the results of the science map graph, there are variables that the faculty should pay special attention to, namely the physical evidence variable. This variable is considered important and is highly expected by students, but the performance shown is low. The variable whose performance must be maintained is the guarantee variable. The variables of responsiveness, reliability and empathy are variables with a low level of hope/importance but the existing performance has been running very well. The author's suggestion is that the faculty continue to maintain the performance of the assurance variable, concentrate more on improving the performance of the physical evidence variable and the responsiveness, reliability and empathy variables which are already running well.

Optimization of alginate extraction conditions from the brown seaweed Dictyota mertensii using a central composite design

This work extracts alginate from Dictyota mertensii, a brown macroalga found on the north coast of northeastern Brazil. A Central Composite Design (CCD) using Response Surface Methodology (RSM) was used to optimize the process of extracting the alginate present in the brown alga Dictyota mertensii, considering the factors of time, temperature, and concentration Na2CO3. Extraction yield (η), sulfate content, intrinsic viscosity ([η]), viscosimetric molar mass (Mv), color parameters (a*, b* e L*), M/G ratio and inhibitory concentration IC50 are model response variables. The Dictyota mertensii algae has its chemical composition expressed. Response surfaces are plotted from the variables studied, a quadratic model was predicted, the influence of factors is analyzed, and response variables are subjected to analysis of variance (ANOVA) and F-test at 95 % confidence. The predicted conditions are experimentally validated. The antioxidant potential was evaluated at seven concentrations (0.2–5.0 mg/mL) based on the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging. The maximum extraction yield was 29.28±0.02 %, and sulfate content ranged from 3.50±0,00 % to 12.33±0.29 %. The maximum values of [η] and Mv were 5.84±0.06 dL/g and 278.00±2.66 kDa, respectively. The alginate showed a dark brown color and M/G ratio < 1, indicating that the extracted alginate provides rigid and compact gels, which allows its application in films, encapsulations, and protecting probiotics. The maximum antioxidant capacity and the IC50 were 54.93±0.27 % and 0.51±0.07 mg/mL, respectively, indicating the material obtained as a moderate natural antioxidant.

Analisis Pengaruh Mutu Pelayanan IGD Terhadap Kepuasan Pasien Di RUMKIT TK II Iskandar Muda Banda Aceh

It can be said that patient satisfaction is an abstract thing and the results vary greatly because basically it really depends on each individual's perception. Patient satisfaction can be said to be fulfilled if the services provided are in accordance with their expectations. The aim of the research is to analyze the Quality of Emergency Room Services on Patient Satisfaction at RUMKIT TK II Iskandar Muda Banda Aceh. The research design used in this research is an analytical survey with a cross sectional design. The population in this study was all 2,058 emergency room patients. The number of samples to be studied is 95 people. Data analysis was carried out using univariate, bivariate and multivariate analysis. The statistical tests used are the chi square test and logistic regression. The results of the chi square test research show that there is an influence of 5 variables, namely reliability, responsiveness, assurance, empathy and physical evidence, which have a p-value &lt;α 0.05, meaning that reliability, responsiveness, assurance, empathy and physical evidence influence patient satisfaction in the RUMKIT TK ER. II Iskandar Muda Banda Aceh and the multivariate test shows that the 5 variables of reliability, responsiveness, assurance, empathy and physical evidence influence the results of the multiple logistic regression test showing that the responsiveness variable is the most dominant with an odds ratio (OR) of 15,104, meaning 15 times influencing patient satisfaction. The conclusion was that the dominant responsiveness variable had the most influence on patient satisfaction at the RUMKIT TK II Iskandar Muda Banda Aceh emergency room. It is recommended for hospitals to adopt policies to increase patient responsiveness in the ER in order to produce optimal patient satisfaction.&#x0D; &#x0D; &#x0D;