Movement Variability Research Articles

The Crux of Human Movement Variability

The Crux of Human Movement Variability

Can we reliably assess spine movement quality in clinics? A comparison of systems to evaluate reliability of spine movement quality in a healthy population

Inertial measurement units (IMUs) have the potential to facilitate a large influx of spine movement and neuromuscular control data to stratify low back pain (LBP) diagnosis and care; however, uncertainties related to validity and reliability are preventing widespread use and acceptance. This study evaluated the concurrent validity of Xsens DOT IMUs relative to gold-standard optical motion capture equipment, and compared within- and between-day reliability of both systems to track spine range of motion (ROM) and movement quality (MQ) by evaluating intraclass correlation coefficients (ICC), standard error of measurement (SEM), coefficient of variation (CV), and minimum detectable difference (MDD). ROM was evaluated during planar ROM movements, and local dynamic stability (LDS; λmax), mean absolute relative phase (MARP) and deviation phase (DP) were estimated from repetitive trunk flexion at 3 speeds, in 15 healthy controls. Results show no statistically significant differences between systems for all metrics, and ICCs ≥ 0.86; therefore, validity was confirmed for tracking primary axis ROM and MQ. IMU data revealed that absolute (C7, T12, and S1) and relative (thoracic, lumbar, and total) ROM was the most reliable metric, followed by λmax, DP, and MARP. Reliability was similar between systems, suggesting that the poorer between-day reliability (higher SEM and CV, lower ICC) observed is attributable to movement variability and sensor placement rather than equipment error. MDDs provide thresholds to researchers and clinicians for identifying change in MQ. Further standardization of evaluated movements/metrics, and patient subgrouping are suggested to improve reliability assessments and refine MDDs in future work.

Cocreation of a Video Feedback Tool for Managing Self-Care at Home With Pairs of Older Adults: Remote Experience-Based Co-Design Study.

Involving older adults in co-design processes is essential in developing digital technologies and health care solutions to enhance self-care management at home, especially for older adults with chronic illness and their companions. Remote co-design approaches could provide technologically sustainable solutions that address their personal needs. This study aimed to cocreate and test the usability of a video feedback tool to facilitate self-care management at home. This experience-based co-design approach involved collaboration between 4 pairs of older adults, 4 researchers, and 2 service designers in three steps: (1) six iterative workshops (5 remote and 1 in person) to cocreate self-care exercises within an existing video feedback tool by identifying factors influencing self-care management; (2) developing and refining the self-care exercises based on suggestions from the older adults; and (3) usability testing of the cocreated exercises with the 4 pairs of older adults in their homes. Among the older adults (68-78 years), 3 adults had heart failure and 1 adult had hypertension. Data were analyzed inductively through thematic analysis and deductively using the USABILITY (Use of Technology to Engage in Adaptation by Older Adults and/or Those With Low or Limited Literacy) framework. The identified influencing factors guiding the contents and format development of 2 new self-care exercises were that pairs of older adults support and learn from each other in performing self-care, which increases their motivation and engagement in practicing self-care at home. The usability test of the 2 new self-care exercises, "Breathing exercises" and "Picking up from the floor," revealed that the pairs found the exercises and the video feedback component valuable for learning and understanding, for example, by comparison of performances highlighting movement variability. However, they found it difficult to manage the video feedback tool on their own, and a support structure or tailored education or training was requested. This study emphasizes that the video feedback tool holds the potential to facilitate learning and understanding in self-care management, which may support motivation. The studied video feedback tool can be beneficial for pairs of older adults managing self-care at home as a complement to traditional health care services, but an accurate supporting structure is required. The effectiveness of the video feedback tool and its integration into existing health care services still need to be assessed and improved through careful design and structured support.

Determining the optimum number of cycles for calculating joint coordination and its variability during running at different speeds: A timeseries analysis

Understanding the intricacies of human movement coordination and variability during running is crucial to unraveling the dynamics of locomotion, identifying potential injury mechanisms and understanding skill development. Identification of minimum number of cycles for calculation of reliable coordination and its variability could help with better test organization and efficient assessment time. By adopting a cross-sectional study design, this study investigated the minimum required cycles for calculating hip-knee, hip-ankle and knee-ankle coordination and their variability using a continuous relative phase (CRP) method. Twenty-nine healthy adults ran on a treadmill at speeds of 9, 12.5, and 16 km.h−1 while 3D kinematic data of their lower limbs were recorded using 6 optoelectronic cameras. Using Intraclass Correlation Coefficient (ICC) analysis, reliability between CRP and its variability (CRPv) in different gait cycles (3, 5, 10, 20, 30) was assessed for each speed. A minimum of 10 cycles was required for CRP calculation across all speeds, whereas CRPv necessitated a minimum of 30 cycles for moderate to good reliability. While increasing the number of cycles improved ICC values for inter-joint CRP, the same trend was not consistently observed for CRPv, emphasizing the importance of separately assessing CRP and its variability metrics.

Gender differences in the use of an upper-extremity exoskeleton during physically and cognitively demanding tasks- a study protocol for a randomized experimental trial.

Upper limb exoskeletons are recommended to alleviate muscle fatigue, particularly in working conditions inducing musculoskeletal discomfort like overhead work. However, wearing an exoskeleton might introduce cognitive-motor interference, affecting performance. Understanding its neural impact and potential gender differences in design effects is crucial. Therefore, the aim of this study is to examine exoskeleton effects addressing cross-gender comparisons, and exploring the impact on cognitive and physical workload in real-world scenarios. The research questions address the impact of exoskeleton use on muscle synergies, upper body posture, cognitive resources, comfort/discomfort, acceptance and usability. The cross-sectional study integrates a multifactorial mixed-measure design. Participants are grouped by gender (female vs. male) and working condition (with vs. without exoskeleton). Motor performance and underlying neuronal correlates (fNIRS) will be analyzed. Based on an a priori sample size calculation, 80 participants (40 female/40 male) will be recruited. Working performance will be assessed by 1. Physical Performance Task (PILE task) and 2. Precision Task (following the Fitts paradigm), while body postures will be monitored with an Xsens motion capture system. Brain activation will be captured with an fNIRS system comprising 32 active optodes. Postural comfort/discomfort, acceptance, and usability will be reported via standardized questionnaires. The study will gain insights into potential gender differences in exoskeleton use and will contribute to designing and optimizing the implementation of exoskeletons by considering muscle synergies, movement variability and cognitive resource allocation. Additionally, the study also highlights user discomfort, a crucial factor that could impede widespread adoption, particularly among females, in real-world scenarios.

Spatial Price Transmission and Dynamic Volatility Spillovers in the Global Grain Markets: A TVP-VAR-Connectedness Approach.

The global food market's escalating volatility has led to a complex network of uncertainty and risk transmission across different grain markets. This study utilizes the Time-Varying Parameter Vector Autoregression (TVP-VAR)-Connectedness approach to analyze the price transmission and volatility dynamics of key grains, including wheat, maize, rice, barley, peanut, soybean, and soybean meal, and their dynamic spillover directions, intensity, and network. By integrating the TVP-VAR-Connectedness model, this research captures the time-varying variability and interconnected nature of global grain price movements. The main findings reveal significant spillover effects, particularly in corn prices, with prices of soybean dominating other grains while prices of peanut and corn experience higher external spillover effects from other grains. The conclusions drawn underscore the imperative for policymakers to consider a holistic perspective of all types of grains when addressing global food security, with this study providing valuable insights for risk management in the grain sector at both global level and country level.

Speaking to a metronome reduces kinematic variability in typical speakers and people who stutter.

Several studies indicate that people who stutter show greater variability in speech movements than people who do not stutter, even when the speech produced is perceptibly fluent. Speaking to the beat of a metronome reliably increases fluency in people who stutter, regardless of the severity of stuttering. Here, we aimed to test whether metronome-timed speech reduces articulatory variability. We analysed vocal tract MRI data from 24 people who stutter and 16 controls. Participants repeated sentences with and without a metronome. Midsagittal images of the vocal tract from lips to larynx were reconstructed at 33.3 frames per second. Any utterances containing dysfluencies or non-speech movements (e.g. swallowing) were excluded. For each participant, we measured the variability of movements (coefficient of variation) from the alveolar, palatal and velar regions of the vocal tract. People who stutter had more variability than control speakers when speaking without a metronome, which was then reduced to the same level as controls when speaking with the metronome. The velar region contained more variability than the alveolar and palatal regions, which were similar. These results demonstrate that kinematic variability during perceptibly fluent speech is increased in people who stutter compared with controls when repeating naturalistic sentences without any alteration or disruption to the speech. This extends our previous findings of greater variability in the movements of people who stutter when producing perceptibly fluent nonwords compared with controls. These results also show, that in addition to increasing fluency in people who stutter, metronome-timed speech also reduces articulatory variability to the same level as that seen in control speakers.

Heart Rate Variability and Interoception in Periodic Limb Movements in Sleep: Interference with Psychiatric Disorders?

Periodic limb movements in sleep (PLMS) are a prevalent disorder characterized by rhythmic, involuntary movements of the lower limbs, such as dorsiflexion of the ankle and extension of the big toe, occurring in periodic intervals during sleep. These movements are often linked to disrupted autonomic nervous system (ANS) activity and altered interoception. Interoception involves perceiving internal bodily states, like heartbeat, breathing, hunger, and temperature, and plays a crucial role in maintaining homeostasis and the mind-body connection. This review explores the complex relationships between PLMS, heart rate variability (HRV), ANS dysregulation, and their impact on psychiatric disorders. By synthesizing the existing literature, it provides insights into how ANS dysregulation and altered interoceptive processes, alongside PLMS, contribute to psychiatric conditions. The review highlights the potential for integrated diagnostic and therapeutic approaches and presents a cause-and-effect model illustrating the mutual influence of psychiatric disorders, ANS dysregulation, PLMS, and interoception.

Temporally enhanced abnormal behavior detection based on multi-channel coupling

Abnormal behavior detection in surveillance videos based on deep learning has becomea hot topic in current research. However, due to the complexity and variability of crowd movement and external environment, detecting abnormal behavior faces great challenges. Current abnormal behavior recognition models have limitations in feature extraction and pay insufficient attention to dynamic temporal features. To address these problems, a spatiotemporal enhancement anomaly detection method based on multi-channel coupling is proposed. Based on the SlowFast network, a multi-channel coupled temporal enhancement module and a spatial enhancement module are introduced respectively to extract more discriminative static and dynamic feature information. A large number of experiments are carried out on three benchmark datasets (Violent Flow, Hockey Fight, and Real-life Violence Situations). The results show that the prediction accuracy of the proposed abnormal behavior recognition method reaches 95.3%、97.3%and respectively 94%, thus verifying the effectiveness of the method.

Climatological Tracking and Lifecycle Characteristics of Mesoscale Convective Systems in Northwestern South America

AbstractMesoscale convective systems (MCSs) are crucial in shaping large‐scale tropical circulation and the hydrological cycle, particularly in Northwestern South America (NwSA), a region marked by complex terrain and significant MCS activity. Understanding MCSs in NwSA is vital due to their impact on precipitation patterns and potential for severe weather events. To enhance this understanding, the ATRACKCS algorithm was developed for tracking convective systems, utilizing precipitation and brightness temperature data sets. This research focuses on documenting the spatiotemporal variability of MCS occurrence, life cycle, and movement. Notably, MCS hotspots were identified to the west of the major orographic features in the region, with maximum occurrences at night, contrasting with the region's typical afternoon peak in land convection. MCS movement is also heavily influenced by topography, with higher velocities on the eastern (windward) side of the Andes compared to velocities on the western (leeward) side. MCSs generally move westward, driven by easterly winds, but this pattern is not consistent throughout the year or region. Northward movement is predominant to the west of the Andes, while southward movement is observed to the east. These seasonal and regional movement variations are linked to factors such as the intertropical convergence zone position, moisture availability, topography, and low‐level jets. This research underscores the complexity of MCSs in NwSA and emphasizes the need for detailed studies on the atmospheric environment shaping these systems. Additionally, it provides a robust 21‐year MCS database for NwSA and an advanced tracking tool for research in various geographic contexts and impact areas.

Inhibitory control and working memory predict rhythm production abilities in patients with neurocognitive deficits

Deficits in rhythm perception and production have been reported in a variety of psychiatric, neurodevelopmental and neurologic disorders. Since correlations between rhythmic abilities and cognitive functions have been demonstrated in neurotypical individuals, we here investigate whether and how rhythmic abilities are associated with cognitive functions in 35 participants with neurocognitive deficits due to acquired brain lesions. We systematically assessed a diverse set of rhythm perception and production abilities including time and beat perception and finger-tapping tasks. Neuropsychological tests were applied to assess separable cognitive functions. Using multiple regression analyses we show that lower variability in aligning movements to a pacing sequence was predicted by better inhibitory control and better working memory performance. Working memory performance also predicted lower variability of rhythmic movements in the absence of an external pacing sequence and better anticipatory timing to sequences with gradual tempo changes. Importantly, these predictors remained significant for all regression models when controlling for other cognitive variables (i.e., cognitive flexibility, information processing speed, and verbal learning ability) and potential confounders (i.e., age, symptom strength of depression, manual dexterity, duration of illness, severity of cognitive impairment, and musical experience). Thus, all rhythm production abilities were significantly predicted by measures of executive functions. In contrast, rhythm perception abilities (time perception/beat perception) were not predicted by executive functions in this study. Our results, enhancing the understanding of cognitive underpinnings of rhythmic abilities in individuals with neurocognitive deficits, may be a first mandatory step to further potential therapeutic implications of rhythm-based interventions in neuropsychological rehabilitation.

Assessing the spatial variability of cage movement and velocity attenuation of an off-bottom oyster farm and its influence on eastern oyster (Crassostrea virginica) growth performance

The global shellfish aquaculture industry has expanded over the last seven decades. Similarly, the size of individual shellfish farming operations has grown in some states. Circulation processes in natural water bodies are dynamic and vary across multiple temporal and spatial scales. How gear installation affects the circulation of currents and waves, and subsequent phytoplankton delivery to crops within farms, is largely unknown. Documenting and understanding variability in wave and current energy within an individual farm could help optimize production. Our study sought to understand the variability in oyster growth attributable to hydrodynamic and atmospheric forcing across an active commercial shellfish aquaculture lease in the Patuxent River, Maryland. We observed a 17 % reduction in water flow downstream of the farm (rho = −0.673, p = 0.002, Spearman rank test), suggesting the bottom cages attenuated downstream current velocity during flood tides. Differences in flow speed and the movement of cages and oysters throughout the farm correlated with variances in oyster shell morphology and oyster survival while in bottom cages. Our results demonstrate the occurrence of variability in production within an individual farm location. Further, our findings suggest that insight into the spatial growth patterns across a lease can be practical for forecasting growth and quality of cultured oysters and may enable growers to strategically place oysters within their farm to improve yield and product consistency.

Associations between pain-related fear and lumbar movement variability during activities of daily living in patients with chronic low back pain and healthy controls

Low back pain (LBP) is a global issue involving biological, psychological, and social factors. Pain-related fear has been shown to influence movement behavior, however, its association with some measures of movement behavior, such as spinal movement variability, remains inconclusive. To further investigate this, spinal kinematics during various activities of daily living (i.e., walking, running, lifting, and stair climbing) of 49 patients with chronic LBP and a group of 51 sex-, age-, and BMI-matched healthy controls were used to calculate lumbar spine movement variability which was quantified using different indices (i.e., coefficient of variation, coupling angle variability in vector coding, deviation phase of the continuous relative phase and an angle-angular velocity variability). General and task-specific pain-related fear was assessed using the Tampa Scale of Kinesiophobia and the Photograph Series of Daily Activities—Short Electronic Version, respectively. Linear regression analyses showed no significant association between movement variability and pain-related fear, however, the sample consisted of younger individuals with moderate disability and with low levels of pain and pain-related fear. In addition, the different variability indices were weakly correlated and varied greatly depending on the method used and the task performed. Therefore, comparisons between studies with different movement variability calculation methods or different activities should be treated with caution.

Evaluation of the Movement and Play Opportunities and Constraints Associated With Containers for Infants.

Containers (eg, strollers, bouncers) are an important part of infants' environment but may negatively impact infant development and health. This study evaluated movement and play opportunities, constraints, and manufacturers' developmental claims for infant containers. Containers were identified through Amazon.com. A content analysis of identified products was conducted to identify movement and visual-manual play opportunities, constraints, and developmental claims. Content was analyzed for 460 containers. Containers varied in their movement and play opportunities; however, most did not incorporate toys and restricted trunk movement, self-directed locomotion, and independent head and trunk control. Containers, especially those with built-in toys, often had claims related to gross motor, sensory, and fine motor development. These findings demonstrate the variability of movement and play opportunities observed across and within categories of infant containers. General recommendations about container use may be less effective than more specific education to parents about selecting and implementing containers.

Directional-Specific Modulation of Postural Control and Stepping Kinematics in Multidirectional Gait Initiation.

Daily living activities present a diverse array of task and environmental constraints, highlighting the critical role of adapting gait initiation (GI) for an individual's quality of life. This study investigated the effects of GI directions, obstacle negotiation, and leg dominance on anticipatory postural adjustments and stepping kinematics. Fourteen active, young, healthy individuals participated in GI across 4 directions-forward, medial 45°, lateral 45°, and lateral 90°-with variations in obstacle presence and leg dominance. Results revealed a consistent decreasing trend in maximum center of pressure displacement, anticipatory postural adjustment duration, step distance, and swing leg velocity with lateral shifts in GI directions, yet the step duration and swing leg heel trajectory were not affected by GI directions except in lateral 90° GI. Center of pressure displacements were intricately scaled to directional propulsive forces generation, and the stepping kinematics were influenced by the directional modifications in movements. With obstacles, modifications in anticipatory postural adjustment metrics and stepping kinematics reflected the obstacle clearance movements. The dominant leg GI exhibited longer step durations and greater movement variability in medial 45° GI. The current investigation of GI factors expands our existing understanding of GI dynamics and offers valuable insights applicable to fall prevention and gait rehabilitation strategies.

Plasma volume response patterns and a physiologic model of ultrafiltration in hemodialysis.

Ultrafiltration (UF) is an essential process of restoring fluid homeostasis during hemodialysis (HD). Fluid shifts across the extracellular compartments during UF, predominantly across the capillary interface and between the macro- and microcirculation. A mismatch between UF and transcapillary fluid transport can lead to hemodynamic instability leading to cardiac morbidity. We wished to study intradialytic fluid transport characteristics and their variation during UF to identify factors that govern variability in transcapillary fluid movement in HD. Twenty-two patients undergoing stable HD sessions were studied to measure and monitor absolute blood and plasma volume throughout UF. A computational mathematical model of predicted plasma volume decay during UF was analyzed with respect to the intradialytic real-time data profile. Pre- and post-dialysis fluid status was assessed using multifrequency bioimpedance spectroscopy. Serum electrolytes, osmolality, and total protein concentration were measured pre- and post-dialysis and during the intradialytic phase. Two distinct profiles of PV responses were detected. 60% of the patients presented plasma volume decline, characterized by a high percentage of volume decrease during the first hour, and a subsequent slower decrease with early rebound. The model was modified to achieve a proper fit of these volume profiles, assuming time-dependent changes in selected parameters governing the refilling flow. Although the modified model could more accurately fit the data, the new parameter values often fell outside of a physiologically acceptable range, suggesting that other factors not included in the classic description of transcapillary fluid transport might be the cause of the observed patterns.

Individual variability in the movement ecology of Northern pike Esox lucius in a highly connected wetland system

Maintaining hydrological connectivity is important for sustaining freshwater fish populations as the high habitat connectivity supports large-scale fish movements, enabling individuals to express their natural behaviours and spatial ecology. Northern pike Esox lucius is a freshwater apex predator that requires access to a wide range of functional habitats across its lifecycle, including spatially discrete foraging and spawning areas. Here, pike movement ecology was assessed using acoustic telemetry and stable isotope analysis in the River Bure wetland system, eastern England, comprising of the Bure mainstem, the River Ant and Thurne tributaries, plus laterally connected lentic habitats, and a system of dykes and ditches. Of 44 tagged pike, 30 were tracked for over 100 days, with the majority of detections being in the laterally connected lentic habitats and dykes and ditches, but with similar numbers of pike detected across all macrohabitats. The movement metrics of these pike indicated high individual variability, with total ranges to over 26 km, total movements to over 1182 km and mean daily movements to over 2.9 km. Pike in the Thurne tributary were more vagile than those in the Ant and Bure, and with larger Thurne pike also having relatively high proportions of large-bodied and highly vagile common bream Abramis brama in their diet, suggesting the pike movements were potentially related to bream movements. These results indicate the high individual variability in pike movements, which was facilitated here by their access to a wide range of connected macrohabitats due to high hydrological connectivity.

Darts fast-learning reduces theta power but is not affected by Hf-tRNS: A behavioral and electrophysiological investigation

Sports trainers have recently shown increasing interest in innovative methods, including transcranial electric stimulation, to enhance motor performance and boost the acquisition of new skills during training. However, studies on the effectiveness of these tools on fast visuomotor learning and brain activity are still limited. In this randomized single-blind, sham-controlled, between-subjects study, we investigated whether a single training session, either coupled or not with 2 mA online high-frequency transcranial random noise stimulation (hf-tRNS) over the bilateral primary motor cortex (M1), would affect dart-throwing performance (i.e., radial error, arm range of motion, and movement variability) in 37 healthy volunteers. In addition, potential neurophysiological correlates were monitored before and after the training through a 32-electrode portable electroencephalogram (EEG). Results revealed that a single training session improved radial error and arm range of motion during the dart-throwing task, but not movement variability. Furthermore, after the training, resting state-EEG data showed a decrease in theta power. Radial error, arm movement, and EEG were not further modulated by hf-tRNS. This indicates that a single training session, regardless of hf-tRNS administration, improves dart-throwing precision and movement accuracy. However, it does not improve movement variability, which might require multiple training sessions (expertise resulting in slow learning). Theta power decrease could describe a more efficient use of cognitive resources (i.e., attention and visuomotor skills) due to the fast dart-throwing learning. Further research could explore different sports by applying longer stimulation protocols and evaluating other EEG variables to enhance our understanding of the lasting impacts of multi-session hf-tRNS on the sensorimotor cortex within the framework of slow learning and training assistance.

Ergonomic Considerations for Practicing Massage Therapists.

The physical demands and repetitive movements performed by massage therapists during a treatment increase the risk for work-related musculoskeletal disorders. While massage therapy meets the level of heavy physical demand, the ergonomic risk of performing a massage was previously unknown. The Massage Therapy Foundation undertook a job task analysis to be used by educators, employers, and clinicians to create an optimal work environment. Data collected via survey were used to create the protocol for an onsite data collection where massage therapists were evaluated on the ergonomic risk factors by trained ergonomists. The results of the job task analysis found the highest variability in movement when the massage therapist was treating the neck prone, neck supine, and leg prone. When the massage therapists did not change positions during a stroke, there was increased forward flexion of the trunk which increased postural stress on the extensors of the back and neck. Strokes such as effleurage which can span the entire length of the body part had the highest cumulative load, requiring postures that put mild biomechanical stress on the shoulders (90% of the time), neck (70% of the time), and trunk (60% of the time). The forward-bending posture of the massage therapist increases the eccentric demands of the therapist's neck and back musculature, thereby increasing fatigue and leading to an increase in the chance of overuse injury. The job task analysis recommends the massage therapist monitor the duration of application in an unsupported position, take more time between sessions, work in an optimum environment, including correct table height, and have a healthy, active lifestyle to maintain career longevity.

Experimentally induced pain increases absolute but not relative errors and reduces variability in joint repositioning of the knee joint in healthy participants

BackgroundJoint position sense (JPS) plays an important role in knee joint function. Despite the possible influence of pain on the proprioceptive system, the effects of experimental muscle pain on knee JPS have not been studied. ObjectivesTo investigate if experimentally induced muscle pain affects knee JPS in healthy participants. MethodsMeasurements of knee JPS were conducted before and after the injection of 5.8% sterile hypertonic saline in the vastus medialis muscle of 26 healthy physically active adults. Knee JPS was assessed through a passive/active repositioning paradigm in target angles of 15°, 45° and 60° using an isokinetic dynamometer. Absolute and relative angular errors were calculated. The coefficient of variation analysis was used to assess differences in the angles’ variability during the repositioning task. ResultsAbsolute angular error increased in all three angles following experimentally induced pain. The difference was statistically significant at 45° (p = 0.003, d = 0.6) and 15° (p = 0.047, d = 0.4) but not at 60° (p = 0.064, d = 0.4). Relative error did not show directional bias at 45° (p = 0.272, d = 0.2), 15° (p = 0.483, d = 0.1) or 60° (p = 0.091, d = 0.3). The coefficient of variation analysis revealed a statistically significant reduction in variability at angles of 60° (p = 0.002, d = 0.7) and 15° (p = 0.031, d = 0.4) after the pain intervention. ConclusionThe presence of experimentally induced muscle pain affects the ability of healthy participants to accurately reposition the knee at two angles of knee flexion and reduces movement variability during the repositioning task. Further research is required to determine if these deficits also impact patients with clinical knee pain.