Value Of High-resolution MRI Research Articles

The value of high-resolution MRI in the diagnosis, efficacy of treatment, and prognosis of central nervous system vasculitis.

To explore the high-resolution magnetic resonance imaging (HR-MRI) characteristics of central nervous system (CNS) vasculitis and to explore the value of HR-MRI in the treatment effect and prognosis evaluation of CNS vasculitis. During the follow-up of 24 patients diagnosed as CNS vasculitis by the Second Hospital of Hebei Medical University, 3.0T HR-MRI was used for imaging examination and HR-MRI characteristics were analysed. The affected vessel wall of 24 patients showed diffuse uniform centripetal thickening. The HR-MRI examination showed varying degrees of lumen stenosis, including 5 cases (20.8%) involving a single arterial segment, and 19 cases (79.2%) involving multiple arterial segments. And most cases (92.9%) showed grade 2 enhancement of the involved vessel wall. Except for one case involving the basilar artery at the same time, the remaining 23 cases involved only the anterior circulation vessels. We analysed and compared the affected vessels between the relapsed group and the non-relapsed group, and found that the average number of involved vascular segments was 6.5 ±3.4 (3-11) in the relapsed group and 3.5 ±2.1 (1-8) in the non-relapsed group, with a significant difference between the two groups (p = 0.039). The CNS vasculitis was more likely to involve the anterior circulation vessels. The number of affected vascular segments in the relapsed group of CNS vasculitis was higher than in the non-relapsed group, suggesting that the more vascular segments involved, the more prone to recurrence.

The value of high-resolution MRI in the differential diagnosis of Moyamoya disease and atherosclerosis-related Moyamoya syndrome

Objective To explore the value of high-resolution MRI(HR-MRI) on clinical application in the differential diagnosis between Moyamoya disease(MMD) and atherosclerosis-related Moyamoya syndrome (A-MMS). Methods Seventeen cases of patients with MMD and 18 cases of patients with A-MMS in our hospital from January 2014 to September 2015 were prospectively enrolled in the study. Record the clinical data and the proximal middle cerebral artery (M1 portion) performance on HR-MRI, the max-vessel area, the min-vessel area, the max-lumen area, the min-lumen area, the wall max-thickness, the styles of M1 portion thickening (eccentric or concentric), whether the wall was enhanced or not, and analysis the recorded data statistically, t test and χ2 test were used for the statistical analysis. Results The wall max-thickness of MMD group was (0.94 ± 0.17) mm, which was smaller than that in A-MMS group (1.23 ± 0.42) mm, there was statistic significance (t= -2.977, P=0.006). The cases of M1 portion non-enhancement was 15, slight enhancement 2, strong enhancement 0 in MMD group, and non-enhancement 5, slight enhancement 5, strong enhancement 8 in the A-MMS group, the difference was significant statistically (χ2= 9.794, P=0.001). The cases of M1 portion concentric thickening was 16, 9 cases in the A-MMS group, there was statistic difference between them (χ2=6.317, P=0.012). Wall concentric thickening diagnose the MMD with a sensitivity of 94.1% (16/17), specificity of 50.0% (9/18), accuracy of 71.4% (25/35). Wall strong enhancement appear in the A-MMS with a sensitivity of 44.4% (8/18), specificity of 100%(17/17), accuracy of 71.4% (25/35).With a cut-off the maximum wall thickness of 1.2 mm could be used to noninvasively differential diagnose the MMD and A-MMS with a sensitivity of 55.6% (10/18), specificity of 88.2%(15/17), accuracy of 71.4%(25/35). Conclusion HR-MRI is a good tool for the differential diagnosis between MMD and A-MMS. Key words: Moyamoya disease; Magnetic resonance imaging; Diagnosis, differential

Bilateral ica-mca stenosis patients the value of high resolution mri in distinguish moyamoya from atherosclerotic

Bilateral ica-mca stenosis patients the value of high resolution mri in distinguish moyamoya from atherosclerotic

Value of high resolution MRI in the diagnosis of pleural disease

目的 探讨高分辨磁共振成像(high resolution magnetic resonance imaging, HR-MRI)对胸膜病变的诊断价值.方法对5例正常志愿者和44例胸膜病变患者行常规MRI和HR-MRI检查,对其中20例进行了图像对比噪声比(CNR)与信号强度比(SIR)的测量,比较分析常规MRI和HR-MRI对胸膜病变的诊断价值.结果 HR-MRI T1WI对5例正常人胸壁主要结构的显示情况明显优于常规MR T1WI (P 0.05). 常规MRI与HR-MRI+常规MRI对良、恶性胸膜病变的鉴别诊断的敏感性分别为72%、 88%,特异性为53%、 75%,正确率为68%、 84%,阳性预测值为82%、90%,阴性预测值为44%、69%.但常规MRI与HR-MRI相结合对良恶性胸膜病变的鉴别诊断价值与单纯的常规MRI比较无明显差异(P>0.05).结论 HR-MRI提高了图像空间分辨率,增加了胸膜病变与肋间肌信号的对比,并且可以清楚地显示最内肋间肌及其内侧的胸膜外脂肪线等邻近胸膜的胸壁深层结构,有利于发现早期胸膜病变的胸壁浸润,在临床工作中 HR-MRI可作为MRI检查的重要补充手段。