An entire forging process for heavy long-axis forgings was divided into three steps:squaring, stretching, chamfering and rounding. Researches of forging process are now focused on the optimization of stretching, but the effect of squaring or chamfering and rounding on the forging quality is neglected. This article is in view of the problems that titanium alloy heavy long-axis forgings were prone to crack and forging process parameters were not easy to control in squaring. Using the Deform software, from strain, damage, forging required load it analyzed that the fillet radius of V-shaped anvil edge influenced quality of titanium alloy heavy long-axis forgings of different diameters in squaring, then we concluded the best combination between diameter of titanium alloy heavy long-axis forgings and fillet radius of V-shaped anvil edge. It provides basis for improving the quality of this kind of forging in squaring.