UV-vis Absorption Studies Research Articles

Green synthesized silver nanoparticles using Nelumbo nucifera root extract for efficient protein binding, antioxidant and cytotoxicity activities

Silver nanoparticles (AgNPs) with a mean particle size of ∼16.7nm were synthesized using an eco-friendly reducing material, aqueous Nelumbo nucifera root extract. Rapid reduction resulted in the formation of polydispersed nanoparticles. The formation of AgNPs was characterized by surface plasmon resonance, which was determined by ultraviolet–visible (UV–Vis) spectroscopy (band at 412nm), Fourier transform infrared spectroscopy, scanning electron microscopy-energy dispersive X-ray spectroscopy, transmission electron microscopy and X-ray diffraction. The interaction of the green synthesized AgNPs with Bovine Serum Albumin (BSA) at various temperatures was investigated. Fluorescence quenching, synchronous and resonance light scattering spectroscopy along with UV–Vis absorption studies revealed the efficient binding between BSA and the AgNPs. In addition, the AgNPs exhibited moderate antioxidant and cytotoxicity activities against HeLa cell lines.

Synthesis, DNA binding and complex formation reactions of 3-amino-5,6-dimethyl-1,2,4-triazine with Pd(II) and some selected biorelevant ligands

With the purpose of studying the binding behavior of Pd(II) complexes with DNA as the main biological target, and their ability to penetrate reasonably into tumour cells and destroy their replication ability, Pd(ADT)Cl2 complex was synthesized and characterized, where ADT is 3-amino-5,6-dimethyl-1,2,4-triazine. Stoichiometry and stability constants of the complexes formed between various biologically relevant ligands (amino acids, amides, DNA constituents, and dicarboxylic acids) and [Pd(ADT)(H2O)2]2+ were investigated at 25°C and at constant 0.1moldm−3 ionic strength. The concentration distribution diagrams of the various species formed are evaluated. Further investigation of the binding properties of the diaqua complex [Pd(ADT)(H2O)2]2+ with calf thymus DNA (CT-DNA) was investigated by UV–vis spectroscopy. The intrinsic binding constants (Kb) calculated from UV–vis absorption studies was calculated to be 2.00×103moldm−3. The calculated (Kb) value was found to be of lower magnitude than that of the classical intercalator EB (Ethidium bromide) (Kb=1.23(±0.07)×105moldm−3) suggesting an electrostatic and/or groove binding mode for the interaction with CT-DNA. Thermal denaturation has been systematically studied by spectrophotometric method and the calculated ΔTm was nearly 5°C, supporting the electrostatic and/or groove binding mode for the interaction between the complex and CT-DNA

Synthesis, molecular structure, biological properties and molecular docking studies on Mn(II), Co(II) and Zn(II) complexes containing bipyridine-azide ligands.

Metal complexes of the type Mn(bpy)2(N3)2 (1), Co(bpy)2(N3)2·3H2O (2) and Zn2(bpy)2(N3)4 (3) (Where bpy=2,2-bipyridine) have been synthesized and characterized by elemental analysis and spectral (FT-IR, UV-vis) studies. The structure of complexes (1-3) have been determined by single crystal X-ray diffraction studies and the configuration of ligand-coordinated metal(II) ion was well described as distorted octahedral coordination geometry for Mn(II), Co(II) and distorted square pyramidal geometry for Zn(II) complexes. DNA binding interaction of these complexes (1-3) were investigated by UV-vis absorption, fluorescence circular dichroism spectral and molecular docking studies. The intrinsic binding constants Kb of complexes 1, 2 and 3 with CT-DNA obtained from UV-vis absorption studies were 8.37×10(4), 2.23×10(5) and 5.52×10(4)M(-1) respectively. The results indicated that the three complexes are able to bind to DNA with different binding affinity, in the order 2>1>3. Complexes (1-3) exhibit a good binding propensity to bovine serum albumin (BSA) proteins having relatively high binding constant values. Gel electrophoresis assay demonstrated the ability of the complexes 1-3 promote the cleavage ability of the pBR322 plasmid DNA in the presence of the reducing agent 3-mercaptopropionic acid (MPA) but with different cleavage mechanisms: the complex 3 cleaves DNA via hydrolytic pathway (T4 DNA ligase assay), while the DNA cleavage by complexes 1 and 2 follows oxidative pathway. The chemical nuclease activity follows the order: 2>1>3. The effects of various activators were also investigated and the nuclease activity efficacy followed the order MPA>GSH>H2O2>Asc. The cytotoxicity studies of complexes 1-3 were tested invitro on breast cancer cell line (MCF-7) and they found to be active.

TiO2/ZnO core/shell nano-heterostructure arrays as photo-electrodes with enhanced visible light photoelectrochemical performance

The present article reports a facile method for preparing the vertically-aligned 1D arrays of a new type of type II n–n TiO2/ZnO core/shell nano-heterostructures by growing the nano-shell of ZnO on the electrochemically fabricated TiO2 nanotubes core for visible light driven photoelectrochemical applications. The strong interfacial interaction at the type II heterojunction leads to an effective interfacial charge separation and charge transport. The presence of various defects such as surface states, interface states and other defects in the nano-heterostructure enable it for improved visible light photoelectrochemical performance. The presence of such defects has also been confirmed by the UV-vis absorption, cathodoluminescence, and crystallographic studies. The TiO2/ZnO core/shell nano-heterostructures exhibit strong green luminescence due to the defect transitions. The TiO2/ZnO core/shell nano-heterostructures photo-electrode show significant enhancement of visible light absorption and it provides a photocurrent density of 0.7 mA cm−2 at 1 V vs. Ag/AgCl, which is almost 2.7 times that of the TiO2/ZnO core/shell nano-heterostructures under dark conditions. The electrochemical impedance spectroscopy results demonstrate that the substantially improved photoelectrochemical and photo-switching performance of the nano-heterostructures photoanode is because of the enhancement of interfacial charge transfer and the increase in the charge carrier density caused by the incorporation of the ZnO nano-shell on TiO2 nanotube core.

Structural and optical properties of Cd and Mg doped zinc oxide thin films deposited by pulsed laser deposition

The 7 wt % Cd doped and 15 wt % Mg doped ZnO thin films were deposited on quartz substrate by pulse laser deposition system. The structural and optical properties of the prepared ZnO, Cd:ZnO and Mg:ZnO films were investigated by X-Ray diffraction (XRD), photoluminescence and UV-Vis spectroscopy techniques. XRD results indicate that the doped ZnO films maintain wurtzite crystal symmetry without any defects and are oriented along c- axis. Photoluminescence studies show a sharp band edge emission peak at 384 nm for pure ZnO film. This peak is blue shifted to 381 nm with Cd doping and red shifted to 395 nm with Mg doping. UV visible absorption studies reveals a decrease in band gap with Cd doping and an increase in band gap with Mg doping.

Anion Binding Properties of Alkynylplatinum(II) Complexes with Amide-Functionalized Terpyridine: Host-Guest Interactions and Fluoride Ion-Induced Deprotonation.

Molecular sensors able to detect ions are of interest due to their potential application in areas such as pollutant sequestration. Alkynylplatinum(II) terpyridine complexes with an amide-based receptor moiety have been synthesized and characterized. Their anion binding properties based on host–guest interactions have been examined with the use of UV-vis absorption and emission spectral titration studies. Spectral changes were observed for both complexes upon the addition of spherical and nonspherical anions. Their titration profiles were shown to be in good agreement with theoretical results predicting a 1:1 binding model, and the binding constants were determined from the experimental data. Drastic color changes from yellow to orange–red were observed for one of the complexes upon titration with fluoride (F−) ion in acetone. These changes were ascribed to the deprotonation of the amide functionalities induced by F− ion, and this was confirmed by the restoration of spectral changes upon addition of trifluoroacetic acid to the F− ion–complex mixture as well as by electrospray ionization mass spectrometry (ESI-MS) data.

Crafting Semiconductor Organic-inorganic Nanocomposites Via Placing Conjugated Polymers in Intimate Contact with Nanocrystals for Hybrid Solar Cells

Recent advances in the synthesis and assembly of nanocrystals (NCs) provide unique opportunities to exploit NCs for the development of next generation organic/inorganic hybrid solar cells as one of the most promising alternatives to Si solar cells to deliver efficient energy conversion with inexpensive fabrication. Herein, we report two simple yet robust routes to conjugated polymer-quantum rod (CP-QR) nanocomposites, dispensing with the need for ligand exchange chemistry. In the first strategy CdSe QRs were passivated with bromobenzylphosphonic acid (BBPA) which not only induced elongated growth but also functionalized the CdSe QR surface, forming BBPA-CdSe QRs. Subsequently, P3HT-CdSe QRs were yielded by Heck coupling of vinyl-terminated P3HT with BBPA-CdSe QRs. The reduced insulating length of BBPA facilitated improved electron interaction between CP and QR, greatly promoting the potential of P3HT-CdSe QR nanocomposites for use in solar cells with enhanced performance. In the second strategy the alkyne–azide cycloaddition, which belongs to an emerging field of click chemistry, was utilized in the preparation of P3HT-CdSe QR nanocomposites. The aryl bromide of BBPA was converted into azide functional group, forming N3-BPA-CdSe QRs. Subsequent catalyst-free Huisgen 1,3-dipolar cycloaddition between ethynyl-terminated P3HT and N3-BPA-CdSe QRs successfully yielded intimate P3HT-CdSe QR nanocomposites without introducing any deleterious metallic impurity. The charge transfer occurred at the P3HT/CdSe QR interface and was confirmed by systematic UV-Vis absorption, photoluminescence (PL), and time-resolved PL studies. The nanocomposites made by the catalyst-free click reaction exhibited a faster charge transfer from P3HT to CdSe than those produced by Heck coupling.

Prodigiosin analogue designed for metal coordination: stable zinc and copper pyrrolyldipyrrins.

The pyrrolyldipyrrin motif is found in several naturally occurring prodigiosin pigments. The potential roles of the interactions of prodigiosins with transition metals and the properties of metal-bound pyrrolyldipyrrins, however, have been difficult to assess because of the very limited number of well-characterized stable complexes. Here, we show that the introduction of a meso-aryl substituent and an ethyl ester group during the sequential assembly of the three heterocycles affords a pyrrolyldipyrrin of enhanced coordinating abilities when compared to that of natural prodigiosins. UV–visible absorption studies indicate that this ligand promptly binds Zn(II) ions with 2:1 ligand-to-metal stoichiometry and Cu(II) ions with 1:1 stoichiometry. Notably, no addition of base is required for the formation of the resulting stable complexes. The crystal structures reveal that whereas the tetrahedral zinc center engages two nitrogen donors on each ligand, the pseudosquare planar copper complex features coordination of all three pyrrolic nitrogen atoms and employs the ester group as a neutral ligand. This first example of coordination of a redox-active transition metal within a fully conjugated pyrrolyldipyrrin framework was investigated spectroscopically by electron paramagnetic resonance to show that the 1:1 metal-to-ligand ratio found in the crystal structure is also maintained in solution.

Synthesis And Characterization Of Nanofibers Of Conducting Polyaniline And Its Substitute Derivative

Intrinsically conducting polymers have been extensively studied due to their fascinating electronic properties and potential applications. One dimensional conducting polymer nanostructures have been the focus of quite extensive studies worldwide due to their high aspect ratio, high porosity apart from high surface area to volume ratio. In this paper, we report the synthesis of nanofibers of polyaniline and its substitute derivates and their comparative study in respect of electrical conductivity. Nanofibers of doped polyaniline (PANI), poly(o-methoxyaniline) (POMXA) and poly(o-methylaniline) (POMLA) were synthesized without need of any templates by interfacial polymerization. SEM, TEM, FTIR, UV-VIS and XRD were used to characterize the synthesized conducting polymeric materials. The average diameters of the synthesized nanofibers of conducting polymeric materials were in the range of 70-120 nm. The electrical conductivity was found to be in the range of 0.3 - 1.0 S/cm following the order as POMXA < POMLA < PANI which was found to be closely related to the size dependent electrical properties of the nanofibers. Optical band gap of these polymers was evaluated from UV–VIS absorption studies. Direct and indirect transition energy band gaps were determined from Tauc’s plots. Interfacial polymerization was shown to be readily scalable to produce bulk quantities of nanofibers of substitute derivative of polyaniline.

Facile functionalization of Fe2O3 nanoparticles to induce inherent photoluminescence and excellent photocatalytic activity

Herein, we report the emergence of intrinsic multicolor photoluminescence in Fe2O3 nanoparticles (NPs) ranging from blue, cyan, to green, upon facile functionalization and further surface modification with a small organic ligand, Na-tartrate. Moreover, we have found unprecedented photocatalytic property of the functionalized Fe2O3 NPs in the degradation of a model water-contaminant. Meticulous investigation through UV-visible absorption and fluorescence study along with theoretical support from literature unfolds that ligand-to-metal charge-transfer transition from the tartrate ligand to the lowest unoccupied energy level of Fe3+ of the NPs and d−d transitions centered over Fe3+ ions in the NPs play the key role in the emergence of multiple photoluminescence from the ligand functionalized Fe2O3 NPs. Moreover, vibrating sample magnetometry measurements demonstrate that the surface modification changes the magnetic behaviour of Fe2O3 NPs upon functionalization. We believe that the great potential of our versatile, ferromagnetic, multicolor photoluminescent Fe2O3 NPs would stimulate the development of numerous opportunities toward their biological and technological applications.

Influence of Mn/S molar ratio on the microstructure and optical properties of MnS nanocrystals synthesized by wet chemical technique

Manganese sulfide (MnS) microparticles have been successfully synthesized at three different Mn/S ratios of 1:1, 1:2 and 2:1 by wet chemical technique. The effect of molar ratio on crystal structures, morphologies and optical properties of as-prepared sample has been investigated. The particle size, micro strain and dislocation density of MnS particles have been estimated by modified Scherrer formula from X-ray diffraction peak broadening analysis. It has also identified the phase transformation from the metastable β-MnS into γ-MnS microparticles. This work presents the results of morphological characterization by scanning electron microscope. It is evident from the SEM image that MnS particles are almost spherical in shape. The UV–Visible absorption study revealed to determine the optical band gap of the MnS microparticles which shows a blue shift with decreasing particle size and the observed band gap lies in the range of 6.03–4.70 eV. The photoluminescence spectrum of as-prepared samples showed that the two main emission peaks corresponding to the strong UV blue emissions.

Vitamin B2 in nanoscopic environments under visible light: photosensitized antioxidant or phototoxic drug?

Vitamin B2 has been studied as a conventional antioxidant (in the dark) since its discovery in 1926. The effect of visible light on vitamin B2-containing food has a long history of scientific investigation. Although photodegradation of the vitamin producing several photoproducts is evident in certain experimental conditions, phototoxicity revealing an additional oxidative stress in the medium is also clear from some reports. Here we report the photosensitized antioxidant effect of the vitamin, which is found to be greater than 2 orders of magnitude more efficient than that in the dark condition. The photoinduced antioxidant property is apparently paradoxical compared to the reported phototoxic effect of the vitamin. Our present study unravels a unified picture underlying the difference in character of vitamin B2 under visible light irradiation. UV-vis absorption and fluorescence studies in a number of physiologically relevant nanoscopic environments (micelles and reverse micelles) reveal the antioxidant activity to a well-known oxidative stress marker 2,2-diphenyl-1-picrylhydrazyl (DPPH) as well as a phototoxicity effect resulting in self-degradation of the vitamin. Picosecond-resolved Förster resonance energy transfer (FRET) from the vitamin to the marker DPPH in the biomimetic environments clearly reveals the role of proximity of an oxidizing agent in the photoinduced effect of the vitamin. Our systematic and detailed studies unravel a simple picture of the mechanistic pathway of the photosensitized vitamin in the physiologically important environments leading to the antioxidant/phototoxicity effect of the vitamin. The excited vitamin transfers its electron to the oxidizing agent in proximity for the antioxidant effect, but otherwise it employs oxygen to generate reactive oxygen species (ROS), resulting in phototoxicity/self-degradation.

Erratum to: DNA Binding and Equilibrium Investigation of the Interaction of a Model Pd(II) Complex with Some Selected Biorelevant Ligands

The Pd(DAP)Cl2 complex, where DAP is 2,6-diaminopyridine, was synthesized and characterized. The stoichiometries and stability constants of the complexes formed between various biologically relevant ligands (amino acids, amides, DNA constituents, and dicarboxylic acids) and [Pd(DAP)(H2O)2]2+ were investigated at 25 °C and at constant 0.1 mol·dm−3 ionic strength. The concentration distribution diagrams of the various species formed were evaluated. A further investigation of the binding properties of the diaqua complex [Pd(DAP)(H2O)2]2+ with calf thymus DNA (CT-DNA) was investigated by UV–Vis spectroscopy. The intrinsic binding constants (K b) calculated from UV–Vis absorption studies is 1.04 × 103 mol·dm−3. The calculated (K b) value was found to be of lower magnitude than that of the classical intercalator EB (ethidium bromide) (K b = 1.23 (±0.07) × 105 mol·dm−3), suggesting an electrostatic and/or groove binding mode for the interaction with CT-DNA.

Surface Modification of MnFe2O4 Nanoparticles to Impart Intrinsic Multiple Fluorescence and Novel Photocatalytic Properties

The MnFe2O4 nanoparticle has been among the most frequently chosen systems due to its diverse applications in the fields ranging from medical diagnostics to magnetic hyperthermia and site-specific drug delivery. Although numerous efforts have been directed in the synthesis of monodisperse MnFe2O4 nanocrystals, unfortunately, however, studies regarding the tuning of surface property of the synthesized nanocrystals through functionalization are sparse in the existing literature. Herein, we demonstrate the emergence of intrinsic multicolor fluorescence in MnFe2O4 nanoparticles from blue, cyan, and green to red, upon functionalization and further surface modification with a small organic ligand, Na-tartrate. Moreover, we have found an unprecedented photocatalytic property of the functionalized MnFe2O4 nanoparticles in the degradation of a model water contaminant. Detailed characterization through XRD, TEM, and FTIR confirms the very small size and functionalization of MnFe2O4 nanoparticles with a biocompatible ligand. Proper investigation through UV-visible absorption, steady-state and time-resolved photoluminescence study reveals that ligand-to-metal charge-transfer transition from the tartrate ligand to the lowest unoccupied energy level of Mn(2+/3+)or Fe(3+) of the NPs and Jahn-Teller distorted d-d transitions centered over Mn(3+) ions in the NPs play the key role behind the generation of multiple fluorescence from the ligand-functionalized MnFe2O4 nanoparticles. VSM measurements indicates that the superparamagnetic nature of MnFe2O4 nanoparticles remains unchanged even after surface modification. We believe that the developed superparamagnetic, multicolor fluorescent MnFe2O4 nanopaticles would open up new opportunities as well as enhance their beneficial activities toward diverse applications.

Synthesis and photophysical properties of new ruthenium(II) charge-transfer sensitizers containing a 4,7-bis(E-carboxyvinyl)-1,10-phenanthroline ligand

A series of ruthenium(II) complexes containing carboxyvinyl-conjugated phenanthroline and another auxiliary ligand have been designed, synthesized, and characterized. Starting from [RuCl2(p-cymene)]2, two types of Ru(II) complexes, [Ru(dcvphen)(4,7-R2-phenanthroline)(NCS)2] and [Ru(dcvphen)(4,4′-R2-bipyridine)(NCS)2] (dcvphen = 4,7-bis(E-carboxyvinyl)-1,10-phenanthroline, R = –CH = CHCOOH, –COOH, H), were synthesized by a one-pot reaction in DMF. Final products were obtained as a tetrabutylammonium salt form of Ru(II) complexes with reasonable yields. UV-Vis absorption studies on the newly synthesized Ru(II) complexes were carried out. Furthermore, it was shown that a dye-sensitized solar cell fabricated with representative [Ru(dcvphen)2(NCS)2][TBA]2 complex dye exhibited a reasonable power conversion efficiency of 1.0 %.

Synthesis, characterization and multi-spectroscopic DNA interaction studies of a new platinum complex containing the drug metformin

A new platinum(II) complex; [Pt(Met)(DMSO)Cl]Cl in which Met=metformin and DMSO: dimethylsulfoxide, was synthesized and characterized by 1H NMR, IR, UV–Vis spectra, molar conductivity and computational methods. Binding interaction of this complex with calf thymus (CT) DNA has been investigated by using absorption, emission, circular dichroism, viscosity measurements, differential pulse voltammetry and cleavage studies by agarose gel electrophoresis. UV–Vis absorption studies showed hyperchromism. CD studies showed less perturbation on the base stacking and helicity bands in the CD spectrum of CT-DNA (B→C structural transition). In fluorimeteric studies, the Pt(II) complex can bind with DNA–NR complex and forms a new non-fluorescence adduct. The anodic peak current in the differential pulse voltammogram of the Pt(II) complex decreased gradually with the addition of DNA. Cleavage experiments showed that the Pt(II) complex does not induce any cleavage under the experimental setup. Finally all results indicated that Pt(II) complex interact with DNA via groove binding mode.

Processing temperature driven morphological evolution of ZnO nanostructures prepared by electro-exploding wire technique

This article presents an effective approach for the synthesis of ZnO nanoparticles with desired morphology via an environmentally benevolent electro-exploding wire (EEW) technique. In this process, ZnO nanoparticles evolve through the plasma generated from the parent Zn metal. Compared to other typical chemical methods, electro-exploding wire technique is a simple and economical technique that normally operates in water or organic liquids under ambient conditions. The effect of different processing temperatures in the range (5–80 °C), on the morphology of ZnO nanoparticles is clearly demonstrated. At 5 °C, nanoparticles with spherical morphology are observed. However, elliptical morphology is observed at room temperature and multipod nanorods at 50 °C and 80 °C. The evolution of ZnO phase is investigated with the help of time dependent UV-vis absorption and photoluminescence (PL) studies. The mechanism of formation and different morphologies of ZnO nanoparticles formed are also proposed.

Crystal growth, spectral, structural and optical studies of π-conjugated stilbazolium crystal: 4-Bromobenzaldehyde-4′-N′-methylstilbazolium tosylate

Nonlinear optical (NLO) organic compound, 4-bromobenzaldehyde-4′-N′-methylstilbazolium tosylate was synthesized by reflux method. The formation of molecular complex was confirmed from 1H NMR, FT-IR and FT-Raman spectral analyses. The single crystals were grown by slow evaporation solution growth method and the crystal structure and atomic packing of grown crystal was identified. The morphology and growth axis of grown crystal were determined. The crystal perfection was analyzed using high resolution X-ray diffraction study on (001) plane. Thermal stability, decomposition stages and melting point of the grown crystal were analyzed. The optical absorption coefficient (α) and energy band gap (Eg) of the crystal were determined using UV–visible absorption studies. Second harmonic generation efficiency of the grown crystal was examined by Kurtz powder method with different particle size using 1064nm laser. Laser induced damage threshold study was carried out for the grown crystal using Nd:YAG laser.

Biological screening, DNA interaction studies, and catalytic activity of organotin(IV) 2-(4-ethylbenzylidene) butanoic acid derivatives: synthesis, spectroscopic characterization, and X-ray structure

A series of organotin(IV) carboxylates, [Me2SnL2] (1), [Bu2SnL2] (2), [Oct2SnL2] (3), [Me3SnL] (4), and [Ph3SnL] (5), where L = 2-(4-ethylbenzylidene) butanoic acid, have been synthesized and characterized by elemental analysis, FT-IR, and NMR (1H, 13C, and 119Sn). [Me3SnL] (4) was analyzed by single crystal X-ray analysis which showed polymeric structure with distorted trigonal bipyramidal geometry. The complexes were screened for biological activities including antibacterial, antifungal, and cytotoxic activities. UV–vis absorption studies of HL, 1 and 4 with SS-DNA revealed groove binding as well as intercalation, which may be due to the presence of planar phenyl groups that facilitate interaction with DNA. The determined intrinsic binding constants, 6.04 × 103 M−1 (HL), 9.6 × 103 M−1 (1), and 1.7 × 104 M−1 (4), showed that HL and 1 have less binding strength than 4. The catalytic activities of di- and tri-organotin(IV) complexes were assessed in transesterification of triglycerides (linseed oil) into fatty acid methyl esters (biodiesel). The tri-organotin(IV) complexes have better catalytic activity than their di-analogs.

DNA Assisted Synthesis, Characterization and Optical Properties of Zinc Oxide Nanoparticles

Recently biosynthesis of metal oxide nanoparticles had attracted much attention because of the necessity to develop new clean, ecofriendly and cost effective synthesis techniques. Zinc oxide nanoparticles were prepared by co-precipitation, using DNA, a biomaterial, as capping agent. The nanoparticles obtained are characterized using XRD, SEM, and FTIR. The XRD confirms the crystalline nature and formation of nanoparticle. The optical properties were studied using Photoluminescence spectroscopy and UV-Vis absorption studies. Band gap of the material obtained is 3.63eV higher than the bulk value (3.37eV). Broad and intense luminescence emissions make the material suitable for blue lazing applications. The results are compared with Zinc Oxide nanoparticles prepared using EDTA as capping agent and found to be of better quality in many aspects. If metal oxide nanoparticles can be synthesized using DNA as capping agent will it favor the synthesis of medically useful metal oxide directly into human body? 