Police are frequently the initial responders to situations involving individuals experiencing a mental health crisis. These situations sometimes escalate to the point where police resort to the use of force, resulting at times in injury and, less often, loss of life. This study draws on data from coronial inquest reports of cases involving police use of fatal force against persons with mental illness from one Australian jurisdiction. It examines the contextual factors leading up to these incidents, the personal backgrounds and mental health histories of the individuals in crisis, and the tactical approaches employed by police leading to the use of deadly force. Understanding these insights is crucial as they can potentially guide efforts to reform police practices in dealing with individuals in mental health crises and ultimately may help to prevent fatal outcomes.