AbstractThis paper investigates the effects of magnetohydrodynamics and heat transfer on the peristaltic transport of Prandtl fluid in a vertical endoscopic tube. The reduction of the complexity of the equations governing the flow of Prandtl fluid entails the use of long wavelength and low Reynolds number approximations. These complex equations for the pressure gradient and velocity profile are handled analytically using the perturbation technique with convective boundary conditions, and the temperature and concentration profiles are carefully solved for the exact solution. The frictional forces and pressure rise are also simulated with numerical integration. The resulting formulas for velocity, temperature, concentration, pressure rise, and pressure gradient are graphed using the MATLAB and MATHMATICA software, and the effects of all the different physical parameters are investigated and assessed. The streamlines with five distinct wave types are sketched at the conclusion to show the phenomenon of trapping. It is investigated that the velocity profile rises due to buoyancy forces and falls due to the influence of magnetic forces.