Substance Abuse Research Articles

What Effect does Ideological Extremism have on Mass Shootings? An Assessment of Motivational Inconsistencies, Risk Profiles, and Attack Behaviors

ABSTRACT Much like other violent extremists, some mass shooters embrace inconsistent, mixed, or customized beliefs and attack for a combination of personal and ideological reasons. This makes it difficult to understand what effects ideology has on their behavior. To obtain empirical answers, we studied (1) the frequency of extreme ideological interests and motives among public mass shooters, (2) differences between perpetrators with and without extreme ideological interests, and (3) the degree of consistency between their ideologies and attack outcomes. Findings suggest that from 1966–2023, approximately one-quarter of public mass shooters in the United States had extreme ideological interests and roughly 70 percent of them were partially motivated by those extreme beliefs. Mass shooters with and without extremist interests showed similar rates of childhood trauma, mental health problems, suicidality, crisis, substance abuse, and criminal records, but ideological shooters were more likely to create legacy tokens, use semi-automatic or automatic rifles, kill strangers and non-white victims, and be copycats or role models. It appears extremism was sometimes a correlate and sometimes a cause of their behavior, with a clear effect on shaping some attacks. Nevertheless, inconsistencies were common, and many attackers did not target locations or victims that fit their ideological enemies.

A Study on the Drug Abuse and Crimes Impacts on Youth

A Study on the Drug Abuse and Crimes Impacts on Youth

Modelling the nicotine pharmacokinetic profile for e-cigarettes using real time monitoring of consumers’ physiological measurements and mouth level exposure

Pharmacokinetic (PK) studies can provide essential information on abuse liability of nicotine and tobacco products but are intrusive and must be conducted in a clinical environment. The objective of the study was to explore whether changes in plasma nicotine levels following use of an e-cigarette can be predicted from real time monitoring of physiological parameters and mouth level exposure (MLE) to nicotine before, during, and after e-cigarette vaping, using wearable devices. Such an approach would allow an -effective pre-screening process, reducing the number of clinical studies, reducing the number of products to be tested and the number of blood draws required in a clinical PK study Establishing such a prediction model might facilitate the longitudinal collection of data on product use and nicotine expression among consumers using nicotine products in their normal environments, thereby reducing the need for intrusive clinical studies while generating PK data related to product use in the real world.An exploratory machine learning model was developed to predict changes in plasma nicotine levels following the use of an e-cigarette; from real time monitoring of physiological parameters and MLE to nicotine before, during, and after e-cigarette vaping. This preliminary study identified key parameters, such as heart rate (HR), heart rate variability (HRV), and physiological stress (PS) that may act as predictors for an individual’s plasma nicotine response (PK curve). Relative to baseline measurements (per participant), HR showed a significant increase for nicotine containing e-liquids and was consistent across sessions (intra-participant). Imputing missing values and training the model on all data resulted in 57% improvement from the original’learning’ data and achieved a median validation R2 of 0.70.The study is in its exploratory phase, with limitations including a small and non-diverse sample size and reliance on data from a single e-cigarette product. These findings necessitate further research for validation and to enhance the model's generalisability and applicability in real-world settings. This study serves as a foundational step towards developing non-intrusive PK models for nicotine product use.

Using the Preparation Phase of the Multiphase Optimization Strategy to Design an Antiextremism Program in Bahrain: Formative and Pilot Research.

Extremism continues to raise concerns about conflict and violent attacks that can lead to deaths, injuries, trauma, and stress. Adolescents are especially vulnerable to radicalization by extremists. Given its location in a region that often experiences extremism, Bahrain developed 4 peaceful coexistence lessons and 4 antiextremism lessons to be implemented as part of their Drug Abuse Resistance Education (D.A.R.E.) program. The aim of this study is to report the results of the preparation phase of the multiphase optimization strategy (MOST) to develop a peaceful coexistence program and an antiextremism program implemented by D.A.R.E. officers in Bahrain. We developed conceptual models for the peaceful coexistence and antiextremism programs, indicating which mediators each lesson should target, the proximal outcomes that should be shaped by these mediators, and the distal and ultimate outcomes that the intervention should change. We recruited 20 middle schools to pilot test our research protocol, survey measures, and the existing intervention lessons. A total of 854 seventh and ninth grade students completed a pretest survey, 4 peaceful coexistence intervention lessons, and an immediate posttest survey; and a total of 495 ninth grade students completed the pretest survey, 4 antiextremism lessons, and an immediate posttest survey. A series of 3-level models, nesting students within classrooms within schools, tested mean differences from pretest to posttest. Pilot test results indicated that most measures had adequate reliability and provided promising evidence that the existing lessons could change some of the targeted mediators and proximal outcomes. Specifically, students who completed the peaceful coexistence lessons reported significant changes in 5 targeted mediating variables (eg, injunctive norms about intolerance, P<.001) and 3 proximal outcomes [eg, social skills empathy (P=.008); tolerance beliefs (P=.041)]. Students who completed the antiextremism lessons reported significant changes in 3 targeted mediators [eg, self-efficacy to use resistance skills themselves (P<.001)], and 1 proximal outcome (ie, social skills empathy, P<.001). An effective antiextremism program has the potential to protect youth from radicalization and increase peaceful coexistence. We used the preparation phase of MOST to (1) develop a conceptual model, (2) identify the 4 lessons in each program as the components we will evaluate in the optimization phase of MOST, (3) pilot test the existing lessons, our newly developed measures, and research protocol, and (4) determine that our optimization objective will be all effective components. We will use these results to revise the existing lessons and conduct optimization trials to evaluate the efficacy of the individual lessons.

Effects of Drug and Substance Abuse on Academic Performance among Secondary School Students, Kauma Subcounty, Kilifii County, Kenya

Purpose: The study aims at investigating effects of substance abuse in Kauma Sub County of Kilifi County of the Coast Province. The Purpose is of the study is to uncover the effects of substance abuse and its relation to academic performance in Secondary schools in Kauma, with the purpose of recommending how to address the Situation. Methodology: The study involves Random selection of Schools and random filling of questioners by learners and Teachers. It was pegged on Uri Bronfenbrenner’s’ Ecological Contextual Theory (1979). Which denotes that behavior is controlled by ecological environmental systems that affects positively or negatively the personality of man culminating to the totality of one’s character. Findings: The research found that the cultural norms of Disco Matanga has greatly contributed to Palm wine (Mnazi), Muguka/ Ghat and Marijuana abuse. Efforts by the Presidency to address the issue and stop the vice has met stiff resistance from locals and politicians for their own motives which were not captured in this research. The research also found that 70% of Secondary school students scored D plus and below in National Examinations. Unique Contribution to Theory, Policy and Practice: The research recommends collaborative efforts on addressing drug abuse in secondary school students and the use of Faith based organizations , academic institutions, Intercountry – National and NGO approaches in Guidance and Counselling with emphasis to co-curricular and art therapies to first educate and inform the population on the effects of drug Abuse, the economic strain on both county and national government on rehabilitation and apply the multi sectorial approach to scaffold the emotional, mental, physiological effects on health and academics with subsequent methods to address the issue including further research studies..

Which pediatric practices use substance use consultation services?

Substance use disorders (SUD) are common in adolescents and young adults, though few youth with SUD receive treatment, and rates of medication for substance use disorder treatment are much lower in youth compared to adults. Pediatric primary care could present an opportunity for youth with SUD to access medication, though pediatric providers may need support. Massachusetts has provided a substance use consultation line for pediatric providers since 2018. One large network of independent primary care practices within the state has been further supported by access to resources provided through a grant from the Substance Abuse and Mental Health Services Administration. In this paper, we describe the services provided in Massachusetts and examine whether additional resources are associated with increased use of the consultation line as a marker of provider engagement in SUD treatment.

Workforce estimate to treat mental disorders in the Kingdom of Saudi Arabia

BackgroundMental, neurological, and substance abuse (MNS) disorders describe a range of conditions that affect the brain and cause distress or functional impairment. In the Middle East and North Africa (MENA), MNS disorders make up 10.88 percent of the burden of disease as measured in disability-adjusted life years. The Kingdom of Saudi Arabia (KSA) is one of the main providers of mental health services and one of the largest contributors to mental health research in the region. Within the past decade, mental health resources and services has increased.MethodsWe employ a needs-based workforce estimate as a planning exercise to arrive at the total number of psychiatrists, nurses, and psychosocial care providers needed to meet the epidemiological need of mental health conditions of the population of KSA. Estimates for a potential mental health workforce gap were calculated using five steps: Step 1—Quantify target population for priority mental health conditions. Step 2—Identify number of expected cases per year. Step 3—Set target service coverage for each condition. Step 4—Estimate cost-effective health care service resource utilization for each condition. Step 5—Estimate service resources needed for each condition.ResultsThe planning exercise indicates an epidemiologic need for a total of 17,100 full-time-equivalent (FTE) health care providers to treat priority MNS disorders. KSA appears to have a need-based shortage of 10,400 health workers to treat mental disorders. A total of 100 psychiatrists, 5700 nurses, and 4500 psychosocial care providers would be additionally needed (that is, above and beyond current levels) to address the priority mental health conditions. The shortfall is particularly severe for nurses and psychosocial workers who make up 98.9 percent of the shortfall. This shortage is substantial when compared to other high-income countries. Overall, the workforce needed to treat MNS conditions translates to 49.2 health workers per 100,000 population.ConclusionChallenges to addressing the shortfall are Saudi specific which includes awareness of cultural customs and norms in the medical setting. These challenges are compounded by the lack of Saudi nationals in the mental health workforce. Saudi nationals make up 29.5 percent of the physician workforce and 38.8 percent of the nursing workforce. Policymakers and planners supplement this shortfall with non-Saudi providers, who must be mindful of Saudi-specific cultural considerations. Potential solutions to reducing the shortfall of mental health care workers includes nurse task shifting and training of general practitioners to screen for, and treat, a subset of MNS disorders.

Use of Cannabinoids by People Who Consume Kratom in the United States.

To estimate lifetime, past-year, and past-month prevalence of kratom, cannabis, and cannabidiol-only product use among adults 18 years and older in the United States, using 2 independent datasets. Utilizing (a) the 2022 National Survey on Drug Use and Health (NSDUH) and (b) a 2022 online national convenience sample of adults who use kratom regularly (from our research group at the National Institute on Drug Abuse [NIDA]), we examined key demographic information as well as lifetime, past-year, and past-month substance use and preferences. Among the full sample of adults from the 2022 NSDUH, the prevalence of lifetime use was 49.69% for cannabis, 34.09% for cannabidiol-only products, and 1.93% for kratom. When solely examining participants who have used kratom, both independent datasets showed higher proportions of cannabis use over the lifetime-92.81% (95% confidence interval: 90.31-95.31) in the NSDUH subset and 92.16% (95% confidence interval: 89.37-94.95) in our NIDA sample. Our study demonstrates that people are co-using kratom with cannabis and/or cannabidiol-only products at the same time or during the same time period, though more research is needed to understand people's motivations and practices for such co-use. Co-use might result in herb-herb interactions that may impact research findings and clinical outcomes for people who use kratom.

Effects of Drug Abuse on the Academic Performance of Students of Selected Tertiary Institutions in Lagos, Nigeria

Drug abuse has become an international phenomenon, a torn in the flesh of nations across the globe. It has been identified as one of the precarious vices; an impediment to the academic excellence of students of tertiary institutions; and a threat to the future of the Nigerian nation. The task of the paper was to interrogate the effects of drug abuse on the academic performance of students of selected tertiary institutions in Lagos, Nigeria. A quantitative method of data collection was employed to get the task of the paper done. The work adopted social learning theory as its theoretical framework. The study found peer group pressure, experimental curiosity, remedy for low self-esteem, poor parenting and influence of role models among others as root causes of drug abuse among students of tertiary institutions in Nigeria. The finding revealed that the rise of drug abuse among the students of higher institutions of learning in Nigeria is at an alarming rate; by implication, absenteeism from school activities, loss of memory, lack of seriousness in academic work, declining grades, increased potential for dropping out of school and suspension from school to mention a few are attributed to drug abuse. The study concluded by recommending a peer education intervention strategy, enactment of laws to discourage drug abuse, inclusion of mandatory drug education in all educational programs, constant monitoring of students by parents, and setting up of guidance and counselling offices across the campuses. Constant awareness programmes about the effects of drug abuse on academic achievement are also appropriate.

Eligibility for Substance Use Clinical Trials Among Emergency Psychiatry Patients: The Impact of Exclusion Criteria

Objective: The first objective was to identify common exclusion criteria used in clinical trials. The second objective was to quantify the degree to which these criteria exclude emergency psychiatry patients. Methods: Qualitative Content Analysis was used for the first objective, identifying common exclusion criteria used in recent high-impact substance use clinical trials. A retrospective record review was used for the second objective, which examined the frequency of these exclusion criteria in a 1-month sample of adults receiving psychiatric evaluation in an emergency department. Results: Most trials had exclusions for co-occurring psychiatric problems (76.6%), medical problems (74.0%), prior or current treatment (72.7%), motivation for change (61.1%), pregnancy or lactation (57.1%), or using other specified substances of abuse (54.6%). In the clinical sample, exclusions for co-occurring psychiatric problems would make 94.7% of patients ineligible. Other exclusions had a combined effect of making 76% of patients ineligible. Conclusions: Clinical trials using typical exclusion criteria exclude nearly all emergency psychiatry patients with substance use problems.

Sugar addiction and its role in obesity among adolescents residing in an urban field practice area of Bagalkot: A cross-sectional study

Obesity, a multi-factorial process is showing an increasing trend among children and adolescents leading to increased prevalence of insulin resistance, paving the way for cardio-metabolic risk factors. It has been proposed that certain food items as well as eating habits are addictive in a way that is similar to substances of abuse. Thus, this study was conducted among adolescents to determine the frequency of sugar addiction, the influencing factors and its association with obesity. A cross-sectional study was designed and 250 late adolescents (17–19 years old) chosen from colleges coming under urban field practice area of Bagalkot were enrolled in the study. A self-administered questionnaire which consisted of three sections - socio-demographic details, validated Modified Yale Food Addiction Scale (mYFAS) and Physical Activity Questionnaire for Adolescents (PAQ-A) was used to collect data regarding sugar addiction and physical activity in our study. Sugar addiction was found among 7.6%of adolescents and it was associated with overweight and obesity which was statistically significant (X=42.72, p&amp;#60;0.0001). Factors which significantly contributed to sugar addiction among adolescents were; adolescents staying in hostel (p&amp;#60;0.001), working mother’s (p&amp;#60;0.0001) and socio-economic status (p=0.02). Univariate analysis (unadjusted odds ratio) showed that risk factors such as sugar addiction (Odds ratio 9.6, 95% C.I. 2.18-42.8, p=0.003) and reduced physical activity (Odds ratio 3.8, 95% C.I. 2.02-7.26, p=0.0001) were associated with overweight and obesity.Incorporation of measures against hyper palatable sugary foods into public health policy recommendations and a further detailed evaluation regarding sugar addiction may provide a new insight and help in prevention and treatment of obesity.

Sex and gender differences in the Italian forensic psychiatric population: a residences for the execution of security measures study

Although sex and gender differences are well-known in psychiatry, their research in the forensic psychiatric population is still limited. This study is aimed at bridging this gap by examining gender-specific factors and treatment needs among forensic psychiatric patients who are highly dangerous. By retrospectively analyzing data from a 1-year observational study on the Italian Residences for the Execution of Security Measures (REMS) patients (n = 730), we compared the main sociodemographic, clinical, and criminological variables between n = 80 female and n = 650 male patients. Female offenders exhibited a higher prevalence of personality (p < 0.001) and depressive disorders (p < 0.001), as well as more severe crimes leading to REMS admission, notably homicide or attempted homicide (p < 0.05). Furthermore, female offenders had a less frequent history of substance abuse (p < 0.001) than male offenders. Despite these differences, there was no evidence of gender-based differences in different sociodemographic and clinical parameters. This study highlights gender differences in forensic psychiatric patients and underscores the importance of nuanced assessment for implementing tailored interventions in forensic psychiatric care.

The effect of cognitive behavioral therapy-based psychoeducation on substance abuse proclivity in adolescent smokers

ABSTRACT Aim The aim of this study is to determine how CBT-based psychoeducation affects substance abuse proclivity in adolescent smokers. Materials and Methods The study is an experimental study model with pretest–posttest control group. As a result of the power analysis carried out for the sample of the study, the sample size was calculated to be 110 adolescent smokers at a significance level of 0.05, confidence interval of 95%, an effect size of 0.7, and power of population representation of 0.95. A Descriptive Characteristics Form and SAPS were used to collect the data. The experimental group received eight sessions of cognitive-behavioral therapy-based psychoeducation. No educational program was applied to the control group. The data were analyzed using number, percentage, mean, standard deviation, chi-square, dependent samples t-test and independent samples t-test. Results Substance abuse proclivity was determined in adolescents who smoked cigarettes in the experimental and control groups. The SAPS total score average of the individuals in the experimental group decreased after psychoeducation compared to before psychoeducation. The difference between the posttest SAPS total mean scores of the control and experimental groups was statistically significant. Conclusion CBT-based psychoeducation was found to be effective in reducing substance use proclivities in adolescent smokers.

Physical restraint and associated agitation.

Physical restraint of patients in intensive care units (ICUs) has an estimated prevalence of 50%. Many medical centres do not have specific protocols for physical restraint, and the decision of whether to physically restrain a patient is up to the nursing staff. Disadvantages of physical restraint include injuries, exacerbation of agitation and an increased risk of developing post-traumatic stress disorder (PTSD). To report prevalence and outcomes in terms of morbidity and mortality of physical restraint in general ICU patients in an 800-bed secondary medical centre. This retrospective study included 647 patients admitted to a general ICU in an 800-bed secondary medical centre in Kfar Saba, Israel, between January and December 2020. Data included demographics, medical history, length of stay, need for mechanical ventilation, number of ventilation days, 28-day mortality, reason for admission, agitation rate assessed by Richmond Agitation and Sedation Scale (RASS) score, need for physical restraint and need for anti-psychotics. Among the patients, 40% (256 of 647) required physical restraint. Older adult patients had a greater likelihood of being physically restrained along with those admitted because of sepsis or acute respiratory failure. Among the study sample, 11% (71 of 647) required anti-psychotics. Patients who were restrained had longer duration of ventilation (5.9 ± 8.2 vs. 0.36 ± 1.4 days; p < .001) and higher 28-day mortality (0.26 ± 0.45 vs. 0.07 ± 0.25, Z = 6.86, p < .001). There was no difference in medical history, except for chronic drug abuse, which was more frequent in the restraint group (18 [6.9%] vs. 11 [2.8%], respectively; p = .019), as well as the use of anti-psychotic medications (24 [9.3%] vs. 19 [4.8%], respectively; p = .034) and anti-depressants (55 [21.2%] vs. 59 [14.8%], respectively; p = .042). The restraint group had higher disease severity scores, as reflected in requirements for vasopressor support (174 [67.2%] vs. 69 [17.3%], respectively; p < .001) and need for dialysis (39 [15.1%] vs. 19 [4.8%], respectively; p < .001); higher frequency of in-hospital anti-psychotic treatment (60 [23.2%] vs. 11 [2.8%], respectively; p < .001); a greater tendency for agitation events and more severe agitation scores (episodes of RASS above zero [1.7 ± 4.0 vs. 0.04 ± 0.27, respectively; p < .001] and maximum RASS score [0.19 ± 1.6 vs. 0.01 ± 0.54, respectively; p < .001]). Overall, advanced age, number of ventilation days and need for dialysis were associated with increased 28-day mortality. In the restraint group, advanced age, chronic use of diuretics and the use of dialysis during ICU admission were associated with increased mortality risk. Restrained patients tended to have higher morbidity and mortality during ICU and hospital stays, as well as a greater tendency for agitation events and more severe agitation scores, with an increased need for in-hospital anti-psychotic treatment. These findings regarding patient characteristics might be used to formulate treatment plans to reduce the rate of physical restraint in the ICU. Because restrained ICU patients tend to have higher morbidity and mortality, treatment plans should be formulated to reduce the rate of physical restraint in the ICU. NCT04771793.

Political constructions of people who use drugs in the Philippines: A qualitative content analysis

BackgroundThis paper examines the political constructions of people who use drugs in the Philippines throughout the presidency of Rodrigo Duterte (2016–2022), during which the government engaged in a ‘war on drugs’ and promoted a punitive drug regime. MethodsBuilding on and drawing inspiration from the global drug policy scholarship that has looked at the ways in which drugs are framed and problematised in various domains, this study used qualitative content analysis to review 96 documents from national government agencies - including strategic action plans, directives, memorandums, guidelines, annual reports, and legislative measures. ResultsForemost, the study finds that various terms were interchangeably used to refer to ‘drug users’ - dependent, offender, personality, abuser - and all of them contributed to the problematisation of people who use drugs as a societal “menace”. As “drug dependents”, they were likewise portrayed as necessitating treatment or rehabilitation. Moreover, presented as victims or passive subjects, their agency and subjectivity are not acknowledged in the documents, even as counter-discourses, mainly from opposition lawmakers, challenge these portrayals and call for people-centered, harm reduction approaches. ConclusionOverall, these overlapping framings cast people who use drugs simultaneously as victims, criminals, deviants, and sick individuals to the detriment of their security, health, and well-being - and to the retrogression of drug policy in the country.

Forensic Characterisation of Complex Suicides: A Literature Review

Complex suicides refer to using two or more suicide modes. In the literature, complex suicides are distinguished into planned and unplanned. Using multiple methods is related to ensuring a fatal result or because the first method appears too painful, time-consuming, or ineffective. The review aims to provide an overview of the critical features of complex suicides in the forensic context. The review was conducted by searching online databases (PubMed Central and Scopus) up to March 2023. We identified 52 articles that met the inclusion criteria, describing 261 cases. Suicides were classified as planned in 136 cases (52.1%); 105 cases (40.2%) were defined as unplanned, while in the remaining 20 cases (7.7%), the authors did not propose any classification. In 2/261 (0.8%) cases, four modes were indicated, three modes were observed in 34/261 cases (13%), and in 224/261 (85.8%) cases the suicides were carried out using a combination of two distinct methods. The method most frequently employed in the first instance in unplanned suicides were sharp-force injuries and stabbing, followed by mechanical asphyxia (hanging, self-strangulation, plastic bag suffocation) and a fall from height. Regarding planned suicide, the most frequent suicide methods were asphyxia, intoxication (drugs, substances of abuse, or alcohol), and poisoning via toxic substances. Complex suicides represent a relatively rare entity in forensic pathology; nevertheless, they can be challenging for the forensic pathologist in terms of differential diagnosis compared to homicides, due to the sometimes multifaceted presentation.

Examining the Psychological Measures and Feasibility of Recreational Trail Rides in Reducing Cravings for Addictive Substances among Veterans: A Replication Pilot Study.

Equine-assisted services have been gaining popularity as complementary therapies for a variety of populations with a diversity of diagnoses. Interventions using equines might benefit the military Veteran population through building therapeutic alliance as well as reducing symptoms. This pilot observational study is primarily aimed to investigate safety, feasibility, and acceptability of equine-assisted services for Veterans with substance abuse disorders. It is the second pilot observational study, the first being completed in 2022. Secondary outcomes included recording the impact of trail riding on psychological measures among Veterans at a large Veterans Administration medical center. The study included a total of 32 Veterans who participated in trail riding sessions from May 4, 2022 to August 31, 2022. The study utilized the Positive and Negative Affect Scale, Adult Hope Scale, and Craving Experience Questionnaire to assess changes in positive affect, negative affect, hope components, and substance craving. The results indicated significant reductions in negative affect and substance craving after the first session, with positive effects observed in subsequent sessions. However, demographic and diagnostic variables did not predict significant changes in psychological instruments. Overall, the study demonstrated that trail riding was a safe and feasible intervention and may have potential benefits for improving emotional well-being and reducing substance cravings among Veterans. It is recommended that future studies research mechanisms of action, as well as conduct more rigorous investigations, including controlled trials using larger sample sizes and longitudinal research, to best determine lasting effects of these types of complementary therapies.

Functional seizures and binge eating disorder: A cross-sectional study

ObjectiveFunctional seizures (FS) are brief, involuntary changes in behaviour or consciousness, distinct from epileptic seizures, potentially associated with psychological dissociation. Binge eating disorder (BED) was linked to psychological and somatic dissociation also. However, any connection between FS and BED is insufficiently explored. We aimed to assess BED prevalence in individuals with FS, anxiety/depression (AD), and healthy subjects (HS), to investigate dissociation’s link to binge eating, and to explore psychological characteristics of FS individuals. MethodParticipants underwent evaluations based on ILAE guidelines and DSM-5 criteria, including questionnaires assessing binge eating, dissociation, anxiety, depression and personality traits. Inclusion criteria were age > 18 years, no history of substance abuse, no history of epilepsy, and no use of medications inducing eating disorders. ResultsWe found significantly more frequent and severe binge-eating symptoms in individuals with FS and AD compared to HS. Depression and dissociation correlated with binge-eating symptoms in both AD and FS groups. The PID-5 facet ’Perseveration’ predicted binge-eating attitudes only in FS individuals; they reported more childhood emotional neglect and increased disinhibition compared do AD people. DiscussionThis study underscores the commonality of binge-eating symptoms in FS individuals, emphasizing its association with dissociation symptoms. This finding support the hypothesis of a link between dissociation and eating disorders. Unique clinical characteristics in individuals with FS were identified, as a compulsive dimension related to binge-eating symptoms, providing a comprehensive understanding of their psychological profile and guiding targeted therapeutic interventions.

Converging on Institutional Logics: The Expansion of Syringe Service Programs in a Midwest State

ABSTRACT Institutional logics are theoretical constructs that describe how organizations and other actors make sense of, and organize their everyday practices. This paper describes how syringe service programs (SSPs) have incorporated disparate institutional logics in efforts to meet the needs of a stigmatized population. SSPs are a type of human service organization that allows intravenous drug users (IDUs) to obtain unused needles, stemming the spread of bloodborne infections. Using qualitative interviews with 26 SSP employees at 22 SSP programs in a Midwestern US state, we reveal how these individuals understand how their organizations adapt to different logics (community, state, and professional) during changes in the field. We use Skelcher and Smith’s types of organizational hybridity to describe how SSPs incorporate different institutional logics into their work. Implications for understanding what happens at the organizational and field level as external pressures shape organizational activity and logic adoption are discussed.

T122 - The Controlled Substances Act Regulations on Schedule I Researcher Registrations and the Need to Investigate New Substances of Abuse

T122 - The Controlled Substances Act Regulations on Schedule I Researcher Registrations and the Need to Investigate New Substances of Abuse