Use Of Hydrofluoric Acid Research Articles

Unmasking Fluorinated Moieties on the Surface of Hydride-Terminated Silicon Nanoparticles.

Despite the widespread use of hydrofluoric acid (HF) in the preparation of silicon surfaces, the true nature of fluorinated surface species remains unclear. Here, we employ an array of characterization techniques led by solid-state nuclear magnetic resonance spectroscopy to uncover the nature of fluorinated moieties on the surface of hydride-terminated silicon nanoparticles (H-SiNPs). A structural model that explains the observed trends in 19F and 29Si magnetic shielding is proposed and further supported by quantum chemical computations. Fluorine is incorporated into local oxidation domains on the surface and clustered at the interface of the oxide and surrounding hydride-terminated surface. Silicon sites capped by a single fluorine are also identified by their distinct 19F and 29Si chemical shifts, providing insight into how fluorine termination influences the electronic structure. The extent of fluorine passivation and the effects of fluorine on the optical properties of SiNPs are also discussed. Finally, challenges associated with Teflon contamination are highlighted that future explorations of nanomaterials may have to contend with.

Remarkable Enhancement of Photocatalytic Activity of High-Energy TiO2 Nanocrystals for NO Oxidation through Surface Defluorination.

The superior photocatalytic activity of TiO2 nanocrystals with exposed high-energy (001) facets, achieved through the use of hydrofluoric acid as a shape-directing reagent, is widely reported. However, in this study, we report for the first time the detrimental effect of surface fluorination on the photoreactivity of high-energy faceted TiO2 nanocrystals towards NO oxidation (resulting in a NO removal rate of only 5.9%). This study aims to overcome this limitation by exploring surface defluorination as an effective strategy to enhance the photocatalytic oxidation of NO on TiO2 nanocrystals enclosed with (001) facets. We found that surface defluorination, achieved through either NaOH washing (resulting in an improved NO removal rate of 23.2%) or calcination (yielding an enhanced NO removal rate of 52%), leads to a large increase in the photocatalytic oxidation of NO on TiO2 nanocrystals with enclosed (001) facets. Defluorination processes stimulate charge separation, effectively retarding recombination and significantly promoting the production of reactive oxygen species, including superoxide radicals (·O2-), singlet oxygen (1O2), and hydroxyl radicals (·OH). Both in situ diffuse reflectance infrared Fourier-transform spectroscopy and density functional theory calculations confirm the higher adsorption of NO after defluorination, thus facilitating the oxidation of NO on TiO2 nanocrystals.

HF-free microwave-assisted synthesis of MXene as an electrocatalyst for hydrogen evolution in alkaline media.

MXenes, characterized by their robustness, flexibility, and large surface-to-volume ratio facilitating efficient energy transfer with fast response times, have emerged as promising electrocatalysts for hydrogen generation through electrochemical water-splitting. However, the conventional synthetic route to MXenes typically involves the use of hydrofluoric acid (HF) to obtain MXenes with terminal F-functional groups. Unfortunately, these fluorine groups can negatively impact the electrocatalytic performance of MXenes. Moreover, HF is highly toxic, necessitating the development of more environmentally friendly synthetic methods. In response to these challenges, we have developed a novel HF-free microwave-assisted synthesis approach for MXenes. This method harnesses the benefits of uniform heating, homogeneous nucleation, and rapid crystal development, resulting in MXene crystallites with limited size. Importantly, our microwave-assisted approach utilizes a fluoride-free, less hazardous etchant as compared to HF for the synthesis and functionalization of MXene. The as-obtained MXene exhibits significantly improved performance towards the electrochemical hydrogen evolution reaction in alkaline media. Specifically, it demonstrates an overpotential of 140 mV at a current density of 10 mA cm-2 and a Tafel slope of 84 mV dec-1. These results highlight the potential of our HF-free microwave-assisted synthesis approach for producing high-quality MXenes with enhanced electrocatalytic activity for hydrogen generation.

A unique sustainable chemical method for the recovery of pure silicon from waste crystalline silicon solar panels

The present work suggests a unique approach for recovering pure silicon from end-of-life silicon solar panels by a direct treatment which does not involve the use of Hydrofluoric Acid (HF). Firstly, the better alkaline treatment between NaOH and KOH was determined. Then, effects of HF etching time and concentration were studied by comparing different etching treatments. Metal impurities such as Ag, Sn, and heavy metal Pb decreased considerably during the acid leaching studies with suitable concentrations. The major impurity Aluminium was reduced significantly by a two-step chemical treatment which ensures minimal silicon loss. Although it is possible to recover 4 N pure silicon by both (with and without HF etching) methods, direct treatment is preferred since the process eliminates potential human health and environmental concerns associated with HF. The recovered silicon samples were analysed by ICP-OES to detect impurity concentration, by XRD for phase identification and SEM analysis for surface morphology. The critical doping impurities, boron and phosphorous dropped considerably to 18.7 ppm and ND in direct treatment. Thus, the study not only provides an alternative way for recovering pure silicon without the use of harmful chemicals such as HF, but it also recommends a 6 M nitric acid leaching treatment before the etching procedure to lower the concentration of metallic impurities. The results are based on treatments with commercial grade chemicals which ensures the scalability of the process at commercial batch. The profit analysis of the recoverable metals was carried out and estimated to be nearly $19 for an 18 kg c-Si module.

Hybrid ceramic repair strength, surface roughness, and bond failure, using methylene blue-activated low-level laser therapy, Carbon dioxide, and Ti: Al2O3 laser

AimsTo evaluate the impact of various pretreatment regimes (LLLT, Ti-sapphire laser, CO2, and HFA-S) on hybrid ceramics, specifically focusing on their ability to enhance repair strength and minimize surface roughness (Ra). Material and methodsDiscs were made from hybrid ceramics and after disinfection were randomly divided into four groups based on different surface conditioning techniques. Each group consisted of 15 discs, resulting in a total sample size of 60. dics in group 1 was surface treated with Low-level laser therapy (LLLT) using methylene blue (MB), Discs in group 2 with Ti-sapphire laser, Discs in group 3 with CO2 laser, and discs in group 4 with HFA-S. Five samples from each group were assessed for Ra. The remaining 10 samples from each group underwent repair using a porcelain repair kit in adherence to the planned instructions. The bond strength of each sample in all groups was measured using a universal testing machine. Following the bond strength testing, the specimens from all study groups were analyzed to determine the mode of failure. To evaluate the data, a two-way analysis of variance (ANOVA) was used, followed by post hoc multiple comparisons. ResultsThe highest repair bond strength was observed in group 4 hybrid ceramics pretreated with HFA-S (19.05±0.79 MPa). The lowest repair bond scores were observed in group 1 hybrid ceramics preconditioned with LLLT in the presence of Photosensitizer (13.41±0.36 MPa). The highest Ra scores were exhibited in group 2 surface treated with Ti-sapphire laser (0.0515±0.16 µm) and the lowest Ra scores were observed in Group 4 HFA-S (0.0311±0.79 µm). Predominant bond failure among different investigated groups was cohesive. ConclusionThe current gold standard for hybrid ceramic conditioning is the use of hydrofluoric acid (HFA) combined with a silane coupling agent. Low-level laser therapy with methylene blue photosensitizer is not recommended for the treatment of hybrid ceramics.

Effect of different surface treatment protocols on the bond strength between lithium disilicate and resin cements.

Because the use of hydrofluoric acid (HF) poses health risks if handled improperly, many clinicians prefer to have the ceramic restorations pre-etched in dental laboratories. However, during the try-in procedure, the pre-etched glass-ceramic restorations may be contaminated with saliva resulting in reduced bond strength. This in-vitro study aimed to investigate the effect of different surface treatments on the bond strength of lithium disilicate (LD) glass-ceramic restorations (IPS e.max Press, Ivoclar Vivadent) to two resin cements. One-hundred eighty blocks (4X4X3mm) of LD glass-ceramic were divided into twelve groups (n = 15), of which six received Variolink Esthetic DC (VE) cement and six received RelyX Ultimate (RU) cement, following the surface treatments: G1) Control: Hydrofluoric Acid + Silane (HF + Sil); G2) Hydrofluoric Acid + Saliva + Silane (HF + S + Sil); G3) Hydrofluoric Acid + Saliva + Ivoclean + Silane (HF + S + IC + Sil); G4) Hydrofluoric Acid + Saliva + Phosphoric Acid + Silane (HF + S + P + Sil); G5) Hydrofluoric Acid + Saliva + Monobond Etch & Prime (HF + S + EP); G6) Monobond Etch & Prime (EP). Following treatment, a resin-cement cylinder (2.3mm diameter) was built on the glass-ceramic surface, photocured (20s), stored in distilled water (37°C, 24h) and submitted to the shear bond strength test. Bond strength data (MPa) were subjected to two-way ANOVA and Tukey (α = 0.01). Cement type and surface treatment had a significant effect on the bond strength (p < 0.001) (Table 4). Single-step Monobond Etch & Prime (EP) significantly improved the bond strength of resin-cements to glass-ceramic with and without saliva contamination.

Potential critical sources of error in the analysis of microcharcoal in Greenlandic palynological samples – an initial study

AbstractIt is common practice to count charcoal particles alongside pollen and non‐pollen palynomorphs in palynological samples. The classification of material as charcoal is dependent upon a number of morphological criteria which, in certain geological zones, could be misclassified. In a preliminary study we tested the effects of different preparation techniques on the count result of charcoal from the same samples of Greenland lake sediments. We demonstrate that the use of hydrofluoric acid has a major impact on the number of recorded charcoal particles. We show that detrital biotite is responsible for a large fraction of the particles misclassified as charcoal and suggest that by using a neodymium magnet any inaccuracy can be minimised. This protocol was then applied to further samples which removed the biotite fraction from the total charcoal count.

Enhanced Corrosion Resistance and Biocompatibility of NaMgF3Coating on Mg–Zn–Ca Alloy: An In Vivo and In Vitro Study

The objective of the present work is to investigate the in vitro and in vivo performance of NaMgF3coating on Mg–3Zn–0.2Ca (MZC) alloy for bone applications. NaMgF3coating is developed on MZC alloy by using NaF solution, which prepares the F−containing coating while avoiding the use of hydrofluoric acid, which is of higher toxicity. The dense NaMgF3coating with a thickness of ≈20 μm contributes to reducing the corrosion rate of MZC exposed to Hanks’ solution by ≈43% from 0.7 to 0.4 mm y−1. The NaMgF3coating also depresses the corrosion rate of MZC in vivo, causing the residual volume of the implanted MZC rods to increase from below 70% to ≈90%. Besides, the toughness value of MZC rods coated with NaMgF3after implantation is 2780 MJ m−3, which demonstrates the continuous and sufficient mechanical support that is provided by it for bone repair. Importantly, osteoblasts can adhere and differentiate on the coating surface, and the NaMgF3coating enhanced the biocompatibility and osteogenesis of the MZC alloy. So, the NaMgF3‐coated MZC alloy could be used in bone repair applications.

Novel acid-free process intensification for the synthesis of non-precious metal-nitrogen-carbon electrocatalysts for oxygen reduction reaction

In this work, a set of PGM-free mono-metallic electrocatalysts (FeAD-N-CAF, Co-N-CAF, Mn-N-CAF, Ni-N-CAF) were synthesized using multiple silica templates with a modified acid-free sacrificial support method, characterized and tested for oxygen reduction reaction (ORR) in acidic, neutral and alkaline electrolytes. The removal of the silica template is achieved simultaneously to pyrolysis through the addition of Teflon powder to the mass of precursors before the heat treatment, resulting in a simple, fast and green approach compared to the conventional method based on the use of hydrofluoric acid (HF). Rotating ring disk electrode tests show that the iron-based electrocatalyst, among all, have higher activity for ORR. An electrocatalyst loading study was conducted with FeAD-N-CAF revealing a dual-site reaction mechanism and a maximum activity reached at 700 μg cm−2, while accelerated durability test highlighted its promising stability. This novel synthesis route can be classified as a new intensified sustainable synthesis process.

How to Clean and Safely Remove HF from Acid Digestion Solutions for Ultra-Trace Analysis: A Microwave-Assisted Vessel-Inside-Vessel Protocol.

The complete dissolution of silicate-containing materials, often necessary for elemental determination, is generally performed by microwave-assisted digestion involving the forced use of hydrofluoric acid (HF). Although highly efficient in dissolving silicates, this acid exhibits many detrimental effects (e.g., formation of precipitates, corrosiveness to glassware) that make its removal after digestion essential. The displacement of HF is normally achieved by evaporation in open-vessel systems: atmospheric contamination or loss of analytes can occur when fuming-off HF owing to the non-ultraclean conditions necessarily adopted for safety reasons. This aspect strongly hinders determination at the ultra-trace level. To overcome this issue, we propose a clean and safe microwave-assisted procedure to induce the evaporative migration of HF inside a sealed “vessel-inside-vessel” system: up to 99.9% of HF can be removed by performing two additional microwave cycles after sample dissolution. HF migrates from the digestion solution to a scavenger (ultrapure H2O) via a simple physical mechanism, and then, it can be safely dismissed/recycled. The procedure was validated by a soil reference material (NIST 2710), and no external or cross-contamination was observed for the 27 trace elements studied. The results demonstrate the suitability of this protocol for ultra-trace analysis when the utilization of HF is mandatory.

What Is the Most Effective Technique for Bonding Brackets on Ceramic-A Systematic Review and Meta-Analysis.

Background: There has been an increase in demand for orthodontic treatment within the adult population, who likely receive restorative treatments using ceramic structures. The current state of the art regarding the most effective method to achieve an appropriate bond strength of brackets on ceramic surfaces isn’t consensual. This systematic review aims to compare the available surface treatments to ceramics and determine the one that allows to obtain the best bond strength. Methods: This systematic review followed the PRISMA guidelines and the PICO methodology was used, with the question “What is the most effective technique for bonding brackets on ceramic crowns or veneers?”. The research was carried out in PubMed, Web of Science, Embase and Cochrane Library databases. In vitro and ex vivo studies were included. The methodological quality was evaluated using the guidelines for reporting of preclinical studies on dental materials by Faggion Jr. Results: A total of 655 articles searched in various databases were initially scrutinized. Sevety one articles were chosen for quality analysis. The risk of bias was considered medium to high in most studies. The use of hydrofluoric acid (HF), silane and laser afforded the overall best results. HF and HF plus laser achieved significantly highest bond strength scores in felsdphatic porcelain, while laser was the best treatment in lithium disilicate ceramics. Conclusions: The most effective technique for bonding brackets on ceramic is dependent on the type of ceramic.

Fluoridic Acid in the Infrared Spectroscopy Analysis of Chemical Composition of Organic Matter

Fourier transform infrared spectroscopy (FTIR) assists in investigating functional groups of soil organic matter (SOM). However, the use of this tool is impaired given the low organic carbon levels and high content of oxides in tropical soils, resulting in low quality spectra and in turn requiring the use of hydrofluoric acid (HF). The objective of this study was to verify the efficiency of using HF in removing the mineral fraction and to increase the C concentration to enable visualizing the bands related to SOM in infrared spectra in soil samples under forest system. The HF treatment was efficient in removing mineral components and proportionally increasing C. The FTIR with HF enabled identifying differences between coarse and fine fractions. The spectra of the HF samples showed that the coarse fractions presented bands related to aromatic material and the fine fractions presented more labile components, with the absence of more recalcitrant components.

Comparison between modified LST Fastfloat and conventional HF methods for pollen preparation in highly minerogenic sediments

Pollen analysis is a commonly used method to interpret vegetation and environmental change. The standard pollen preparation technique in minerogenic sediments involves the use of hydrofluoric acid (HF) which is highly toxic. Currently the European legislation requires that hazardous chemicals should be substituted with less hazardous or non-toxic chemicals if possible. In the present paper the authors introduce a safer pollen preparation method, based on the use of low-toxic heavy liquid lithium heteropoly-tungstate (LST Fastfloat) and provide instructions for pollen preparation with the LSTFastflow method. Furthermore, five paired samples were processed from clayey and silty sediments with LST Fastfloat and conventional HF methods and the pollen and spore counting results obtained from these two methods were compared to test if there is statistically significant differences between the taxa. Calculation of the 95% confidence interval revealed statistical agreement in all studied taxa except one taxon in one sample pair. However, the study revealed systematic differences within two taxa, Betula and Pinus. Thus caution is needed when comparing results obtained by HF and heavy liquid (LST Fastfloat) methods.

Cleaning Zirconia Surface Prior To Bonding: A Comparative Study of Different Methods and Solutions

To evaluate resin cement bond strength after removal of salivary contamination from a zirconia surface using different cleaning solutions and air-borne particle abrasion. One-hundred and twenty zirconia specimens (KATANA STML, Noritake) were prepared and divided into 12 groups (n = 10). Groups were subjected to a notched-edge shear bond strength test (ISO 29022) to analyze the bonding efficiency of a resin cement (Panavia V5, Kuraray Noritake Dental Inc.) before and after contamination with saliva. Group 1 (control) was prepared and cemented without salivary contamination. Group 2 was coated with ceramic primer (Clearfil Ceramic Primer Plus, Kuraray Noritake Dental Inc.) then subjected to salivary contamination then tested. Group 3 was contaminated, cleaned by air-borne particle abrasion, ceramic primer and resin cement applied, and tested. Groups 4 to 12 were contaminated, and then different cleaning solutions (water, 4.5% hydrofluoric acid, 35% phosphoric acid, Ivoclean, KATANA cleaner, Zirclean, sodium hypochlorite 4%, and 7.5%) were used to decontaminate the zirconia surface, followed by ceramic primer, resin cement application, and tested.One-way ANOVA and Tukey post-hoc analysis was used to analyze the data. One-way ANOVA showed statistical differences among cleaning procedures (p < 0.001, F = 13.48). Air-borne particle abrasion was the only group which provided a bond strength (21 ± 2.8 MPa) that was not statistically different than the control group in which no contamination occurred (25.3 ± 3.3 MPa) (p = 0.247). The use of hydrofluoric acid and zirconia cleaning solutions resulted in bond strengths values which were not statistically different from each other (17.5-19.1 MPa). Air-borne particle, zirconia cleaning solutions and hydrofluoric acid are feasible to decontaminate the zirconia surface from saliva prior to bonding the restoration.

POSSIBILITIES OF IMPROVING THE SHEAR STRENGTH BETWEEN DIFFERENT TYPE OF CEMENT AND ZIRCONIA CERAMICS: LITERATURE REVIEW

Background: Zirconia ceramics are a modern dental material which has a wide range of application in restoration of frontal and distal teeth. This is due to its improved mechanical properties and aesthetics. Aim: This literature review analyses the possibilities for improvement of the bond strength between zirconia ceramics and different types of cement which are used for fixation of prosthetic constructions. Review Results: The evidence from the literature indicates that preliminary treatment of zirconia ceramics increases the bond strength significantly to the cement. In this respect, different methods and materials are used for the treatment of the zirconium dioxide surface. Some of them include only mechanical treatment with diamond burs, a different type of lasers and sandblasting with aluminum oxide. Other methods have chemical action by the use of hydrofluoric acid and fluoride compounds. According to some data, zirconium structure does not allow etching which leads to application of different type of primers for increasing the shear strength. Studies show that silane application significantly improves the shear bond strength to the cement, as well as, zirconium tensile strength. Optimal results are registered with a combination of treatment with mechanical methods and silane application. Conclusion: Preliminary mechanical and chemical treatment of zirconia surface improves the shear bond strength considerably to the cement. The variety of surface treatment methods complicates the establishment of a standard protocol for fixation of zirconium prosthetic constructions.

CSB urges better refinery inspections, HF substitutes

The US Chemical Safety and Hazard Investigation Board (CSB) has repeated its call for a review of refineries’ use of hydrofluoric acid (HF) and urged owners and regulators to conduct intensive insp...

Pretreatment of Coal by Acid Leaching As Feedstock Preparation For Co-Gasification With Biomass

Co-gasification process of coal and biomass is believed to be one of the promising way to produce hydrogen. The mixing of coal and biomass can solve the problems that usually happened during gasification of pure coal or pure biomass. Furthermore, the presence of synergistic effect between coal and biomass may increase the hydrogen production due to Alkali and Alkaline Earth Metal (AAEM) content in the biomass. However, the synergistic effect may be hindered by the presence of silica in the coal. The present study focuses on the reduction of silica content of coal by acid leaching. Based on the result, it is found that the use of hydrofluoric acid may significantly reduce the silica content shown by the reduction of ash content in the coal. Furthermore, acid leaching process also causes the increase of surface area of the coal which may increase the possibility of AAEM attachment to the surface and thus the gas production may increase as well.

Comparison of Shear Bond Strength Orthodontic Brackets Bonded to Zirconia and Lithium Disilicate Crowns.

Aimof this study was to analyze Shear Bond Strength (SBS) and Adhesive Remnant Index (ARI) of ceramic and metallic orthodontic brackets bonded to zirconia or lithium-disilicate ceramics used for prosthetic restorations, conditioned with hydrofluoric acid (HFA) or phosphoric acid (PhA), as well as to determine the Porcelain Fracture Index (PFI), in order to examine the condition of the ceramic surface after debonding.Material and methodsThe research was conducted on 96 prepared all-ceramic samples divided into 8 groups combined from the type of ceramic material, orthodontic brackets, and surface conditioning. SBS was tested with Universal Testing Machine, and the samples were analyzed using a Scanning Electron Microscope, to determine ARI and PFI. Statistical data were processed using ANOVA, with the level of significance α = 0.05.ResultsLithium-disilicate showed better bond strength in almost all groups. However, no significant difference between the groups was noticed and none of the factors had a significant influence on the mean values of SBS (p>0.05). Nevertheless, ARI significantly depended on the type of bracket (p = 0.005), and PFI significantly depended on the type of etchant (p = 0.029).ConclusionThe use of HFA for surface etching of zirconia and lithium-disilicate, does not cause a significant increase in the SBS values as compared to etching with PhA and silane application. Furthermore, HFA can weaken the surface structure of the ceramic, and considering its toxicity, might not be the best suitable conditioner prior to orthodontic bonding to lithium disilicate, and in particular to zirconia, also taking into account its crystalline structure.

Straightforward and Relatively Safe Process for the Fluoride Exchange of Trivalent and Tetravalent Group 13 and 14 Phthalocyanines.

To avoid the use of hydrofluoric acid, a series of fluorinated trivalent and tetravalent metal-containing phthalocyanines (MPcs) were synthesized using a straightforward one-step halide substitution process using cesium fluoride (CsF) as the fluoride source and by reflux in N,N-dimethylformamide for less than an hour. The resulting fluoro MPcs were characterized and compared to the parent chloro MPcs. In some cases, very little change in properties was observed between the fluoro MPcs and the chloro MPcs. In other cases, such as fluoro aluminum phthalocyanine, a blue shift in the absorbance characteristics and an increase in oxidation and reduction potential of as much as 0.22 V was observed compared to the chloro derivative. Thermo gravimetric analysis was performed on all halo-MPcs, indicating that the choice of halo substitution on the axial position can have an effect on the decomposition or sublimation temperature of the final compound. After initial establishment and characterization of the fluoro MPcs, the halide substitution reaction of difluoro silicon phthalocyanine (F2-SiPc) was further explored by scaling the reaction up to a gram scale as well as considering tetrabutylammonium fluoride (TBAF) as an additional safe fluoride source. The scaled-up reactions producing F2-SiPc using CsF and TBAF as fluoride exchange sources were successfully reproducible, resulting in reaction yields of 100 and 73%, respectively. Both processes led to pure final products but results indicate that CsF, as the fluoride exchange reagent, appears to be the superior reaction process as it has a much higher yield.

Investigation of a Proactive Glass Filler Removal in IC Substrate Build Up Films and its Effect on Topography and Copper Adhesion Reliability

Across all areas within the electronics industry, there is a general trend to push for a smaller footprint and reduce unit size where ever possible. Printed Circuit Board (PCB) production is not exempt from this trend and one of the major challenges facing the industry is the drive to produce an ever increasing interconnect density. While there is a wide range of dielectric materials available to PCB designers, due to their well-balanced properties, the materials of choice often remain those based on epoxy based resins. However for high end applications, where the ability to produce interconnects of the desired size, in combination with other target properties is critical, there has been a switch away from woven glass reinforcement towards a system based on glass particles. Such spheres, typically with diameters in the order of microns, allow for improved thermal expansion control within the final board, and due to their small size also enable smoother surface topographies when compared to the previous glass fibre reinforced materials. Irrespective of the reinforcement system utilized, the desmear operation, which is widely used during the electroless Copper process, can expose the filler material, and especially in the case of the glass sphere fillers, can lead to a reduction in their anchoring in the surrounding resin matrix, which may result with reduced adhesion and potentially blistering of the deposited electroless Copper layer. The use of hydrofluoric acid, is a recognized industrial method for removal of glass fillers, however in addition to the health concerns posed by its use, it has been shown in previous studies, that a complete dissolution of surface exposed glass fillers creates a sponge like structure, which leads to a reduced overall rigidity. This paper presents a wet chemical approach that is not based on hydrofluoric acid, as a means of removal of exposed glass reinforcement materials, and examines its effect on the surface topography prior to Copper plating and on the final Copper adhesion on commonly used substrate build up films. We describe an increased Copper to substrate adhesion where a less drastic means of attacking the glass fillers is employed and propose an explanation by less residual glass fillers on the surface which are easily lifted off by the plated Cu-film. In addition, we show that crevices are created between the remaining surface exposed glass fillers and their surrounding resin matrix, which after being filled during plating act as anchoring points, thus increasing overall adhesion between the dielectric and overlying Copper layer. For commonly used base materials a significant improvement of the blister performance, as well as an enhanced Copper to substrate adhesion was observed. It is clearly understood that the absolute value of peel strength is dependent upon surface topography, which in turn is influenced by the resin curing conditions and the applied desmear process. Nevertheless, we have obtained adhesion improvements through glass filler removal on a number of base materials with a wide range of surface roughness. Typically used within advanced substrate designs, the cleaning of blind micro vias is of paramount importance, and the removal of glass fillers from such features is a challenging task. Within this work, we have shown that the use of additives within the process chemistry can impact the solution exchange within these features so that glass filler removal therein is optimized. Thus, besides increasing Copper to resin adhesion, the employed chemical treatment also facilitates the creation of inner layer connectivity and aids in their final reliability performance.