Use Of African Traditional Medicine Research Articles

Concentration of Toxic Heavy Metals and Phytochemicals in a Medicinal Plant (Asclepias fruticosa) Collected Around Mining Areas in Brits, Pretoria

The use of African traditional medicine in rural and peri-urban areas is common due to its affordability and accessibility. The study aimed to determine the levels of toxic heavy metals in the medicinal plant (Asclepias fruticosa) samples collected around three mining areas in Brits using ICP-OES. The phytochemical screening analysis was done to indicate the absence or presence of different phytochemicals in the medicinal plant. The results of the qualitative phytochemical analysis indicated the presence of flavonoids, alkaloids, proteins, and carbohydrates in Asclepias fruticosa collected from all the mining areas. The results of the heavy metals showed that the mean highest concentration for all the heavy metals was recorded for Mn from the leaves of the medicinal plants. The trend in the heavy metals accumulation was roots > leaves > stems from all the sites, and the differences were significant (p < 0.05). The range of heavy metals in the plant was in the range Mn (12.33 ± 2.31-85.33 ± 51.07 μg.g-1), Zn (10.67 ± 0.58-60.33 ± 0.56 μg.g-1), Cr (3.43 ± 0.06 -34.90 ± 0.10 μg.g-1), Cu (8.67 ± 0.12-18.8 ± 1.57 μg.g-1), Ni (5.67 ± 0.12-23.23 ± 1.7 μg.g-1) and Pb (0.53 ± 0.013-1.59 ± 0.15 μg.g-1). The values of the heavy metals Cr, Zn, and Ni in the plant exceeded the recommended limits set by WHO for human consumption. Heavy metals in the medicinal plant were accumulated in the roots and not translocated to the stems and leaves. It is therefore recommended that communities staying around the mines should be discouraged from picking and using medicinal plants growing around the mines and should be educated on the safety of medicinal plants growing around the mines.

“Piercing the veil into Beliefs”: Christians Metaphysical Realities vis-à-vis Realities on African Traditional Medicine

This paper centres on the contentions between the use of African Traditional medicine and convoluted beliefs among some Christianity groups. It is argued that most Pentecostal churches in Africa vilify African cultural practices and deter their converts from using African traditional medicine. Feelings of disgrace and trepidation when asked about traditional healing frequently make it difficult, particularly for the individuals who have become Christians and have acknowledged western medicine, to reveal their insight into non-western treatments. Against this backdrop, the primary aim of this paper is to unveil the conflict between Christianity and the use of African traditional medicine. The broad aim is to create a platform for a conjectural dialogue towards appreciation for a ‘new world order’ that necessitates an integration of African Traditional Religion and Christianity through adopting a comprehension of cultural differences. The paper draws in the existing scholarly literature on the contention that Pentecostalism do not acclimatize with cultural practices of the African indigenous people preceding persuading them about switching to God who is introduced in the Bible. It has been established that as per the Bible and Christian teachings, the use of traditional medicine is a cursed thing. The authors recommend a confrontation of the healing crisis in Africa through fostering cordial cooperation and of biomedicine, African traditional practitioners and Christian groups.

PLANTS USED BY AFRICAN TRADITIONAL HEALERS IN THE MANAGEMENT OF ORAL DISEASES: A REVIEW

Background: Plants form the basis of African traditional medicine which has contributed to significantly to the reduction of mortality, morbidity and disability due to many diseases. Medicinal plants have been reported to be an essential aspect oral health delivery cutting across all facets of oral health care.
 Method: Publications and reports on the use of African traditional medicine in oral health care were reviewed from published scientific journals, books, reports from national, regional and international organizations, research theses, conference papers and other grey material. International online databases such as MEDLINE, Science Direct, Scopus and Google were also searched up to 2015. Publications were limited to the English and French language
 Results: This review identified medicinal plant use by traditional healers in preventive, therapeutic and surgical aspects in the oral health and also identified some research gaps which further studies should be carried out.
 Conclusion: Medicinal plants has enormous benefits in the management of oral diseases but faces some challenges like toxicity, processing and follow-ups. Research on medicinal plants use in African traditional medicine in oral health is still scanty and most often incomplete.

Biomedical healthcare and African traditional healing in the management of HIV and AIDS: complimentary or competing cosmologies?

In South Africa, African traditional healers and biomedical practitioners play important roles in the management of HIV and AIDS, but provide healthcare services in isolation of each other, despite legislative recognition of both types of healing. An interpretive, qualitative research approach was employed to elicit the views of both groups regarding the feasibility of collaboration. Semi-structured interviews were conducted with a sample of 20 participants with 10 persons from each group. Key findings were that African traditional healers referred their patients to hospitals but never received referrals from biomedical health care practitioners. The traditional healers took precautions to avoid drug interactions between their medicines and antiretrovirals (ARVs). Biomedical healthcare practitioners recommended that traditional medicine only be used externally to avoid interaction with ARVs. Lack of shared knowledge, poor dosages and medical complications due to the use of African traditional medicine were viewed as threats to the collaboration between the two groups, while open communication, research into the efficacy, scientific administration and proper dosages of African traditional medicine were articulated as facilitating factors. The main conclusion was that biomedical practitioners, traditional healers and government officials responsible for formulating healthcare policies need to be involved in devising a framework that would facilitate ways of encouraging collaboration between these two healthcare systems.

The role of the South African Journal of Botany as a vehicle to promote medicinal plant research– A bibliometric appraisal

South Africa's unique flora and extensive use of African traditional medicines has created a unique research opportunity on medicinal plants for local and international scientists. In this paper, submitted to a special issue of South African Journal of Botany(SAJB) dedicated to “sub-Saharan Ethnobotany”, we aim to explore the research landscape on medicinal plant research as published in SAJB. A bibliometric assessment (1982–2017) showed that medicinal plant research represents 24% of the published volume in SAJB and that contributions on this topic are increasing exponentially. Although most papers are broad-basedinvitro screening studies, the range of topics covered is impressive. Antimicrobial (41%) and anti-oxidant (21%) studies dominate the research space with fewer studies focusing on diseases highly relevant to the African continent, e.g. malaria (3%) and tuberculosis (2%). Although the SAJB has contributed greatly to disseminating knowledge on important species (e.g. Aspalathus and Cyclopia) several taxa of potential economic relevance remain poorly investigated (e.g. Adansonia, Bulbine etc.). The citation footprint and authorship networks which have been established attest the pivotal role the SAJB has played to build research capacity and create awareness in this important field of research.

Commercial herbal medicines used as African traditional medicines: Ngoma Herbal Tonic Immune Booster interferes with a rapid urine drug screening test.

The prevalent use of African traditional medicine by the general public has been reported. With commercialisation and marketing, some of the herbal medicines (HMs) used are readily available over the counter, most of them promoted as immune boosters. These commercial HMs have not been taken through clinical trials and other tests that would validate their composition and safety, and other properties such as their effect on laboratory diagnostic tests. To investigate the cross-reactivity of selected HMs with commonly tested drugs of abuse (DoA) using a qualitative rapid urinalysis assay. The six HMs selected were bought from local pharmacies. A rapid urinalysis screening test was performed with the Instant View Multi-Drug of Abuse Test kit from Labstix Diagnostics. Drug-free urine (DFU) was pooled from samples donated by healthy volunteers. Urine samples that had tested positive for DoA were obtained from a pharmacology laboratory. Aliquots of the urine samples were spiked with the HMs in neat and diluted form, and tested at various time intervals. The results for the DFU samples spiked with the HMs remained negative. There were no significant changes in pH or specific gravity of the samples. The results of samples that had tested positive for tetrahydrocannabinol (THC) were not altered by five of the HMs when spiked at 40% v/v. The HM Ngoma Herbal Tonic Immune Booster caused false-negative results for the THC test. An important finding is that the herbal mixture Ngoma Herbal Tonic Immune Booster caused false-negative results for the cannabinoid screening test. It adds to the list of substances that may be potential adulterants of urine for screening tests.

Traditional, complementary and alternative medicine use by HIV patients a decade after public sector antiretroviral therapy roll out in South Africa: a cross sectional study.

BackgroundThe roll out of antiretroviral therapy in the South African public health sector in 2004 was preceded by the politicisation of HIV-infection which was used to promote traditional medicine for the management of HIV/AIDS. One decade has passed since; however, questions remain on the extent of the use of traditional, complementary and alternative medicine (TCAM) by HIV-infected patients. This study therefore aimed at investigating the prevalence of the use of African traditional medicine (ATM), complementary and alternative medicines (CAM) by adult patients in the eThekwini and UThukela Health Districts, South Africa.MethodsA cross- sectional study was carried out at 8 public health sector antiretroviral clinics using interviewer-administered semi-structured questionnaires. These were completed from April to October 2014 by adult patients who had been on antiretroviral therapy (ART) for at least three months. Use of TCAM by patients was analysed by descriptive statistics using frequency and percentages with standard error. Where the associated relative error was equal or greater to 0.50, the percentage was rejected as unstable. A p-value <0.05 was estimated as statistically significant.ResultsThe majority of the 1748 participants were Black Africans (1685/1748, 96.40 %, SE: 0.00045), followed by Coloured (39/1748, 2.23 %, SE: 0.02364), Indian (17/1748, 0.97 %, SE: 0.02377), and Whites (4/1748, 0.23 %, SE: 0.02324), p < 0.05. The prevalence of ATM use varied prior to (382/1748, 21.85 %) and after ART initiation (142/1748, 8.12 %), p <0.05, specifically by Black African females both before (14.41 %) and after uptake (5.49 %), p < 0.05. Overall, 35 Black Africans, one Coloured and one Indian (37/1748, 2.12 %) reported visiting CAM practitioners for their HIV condition and related symptoms post ART.ConclusionDespite a progressive implementation of a successful antiretroviral programme over the first decade of free antiretroviral therapy in the South African public health sector, the use of TCAM is still prevalent amongst a small percentage of HIV infected patients attending public healthcare sector antiretroviral clinics. Further research is needed to explore reasons for use and health benefits or risks experienced by the minority that uses both conventional antiretroviral therapy with TCAM.

A review of the role of African traditional medicine in the management of oral diseases

Background: Poverty, inadequacy of health services, shortage of health workers, infectious diseases scourges, rampant shortage of drugs and equipment in existing health facilities make traditional medicine an important component of healthcare in Africa, especially in oral health care. This review was done to document the role of African traditional medicine in oral health care delivery in order to provide a comprehensive documentation, identify research gaps, and suggest perspectives for future research. Materials and Methods: Available references or reports in English and French on the use of African traditional medicine in oral health care were consulted from published scientific journals, books, reports from national, regional and international organizations, theses, conference papers and other grey materials. Literature was searched on international online databases such as Pubmed, MEDLINE, Science Direct, Scopus and Google using the MeSH words “Traditional medicine or healer”, “oral health”, “dental caries”, “dental”, “primary oral health care’ and “medicinal plants”. Results: Contemporary African communities operate a pluralistic health system whereby highly sophisticated biomedical health care co-exists and even competes with traditional medical practices. Though most patients opt for dual consultations, the introduction of biomedicine has never replaced traditional indigenous medicine and traditional healers are consulted for several reasons making dual treatment a common occurrence in many communities. Factors such as the lack of health care workers, inequalities in the health sector due to socio-cultural and socio-economic disparities prevent people from patronising both health care systems. Therapeutic methods used by African traditional healers include herbalism, psychotherapy, simple surgical procedures, rituals and symbolism. The types of medications used by traditional healers were classified as preventive and prophylactic medications. Some practices of traditional healers included tooth extractions with medicinal plants and also in other practices resulting in exposure to blood; practices involving the use of shared instruments had been reported to be responsible for the transmission of HIV/AIDS. Other harmful practices include gemectomy, uvulectomy and different forms of infant oral mutilations. Conclusion: Traditional healers provide dental care, but their work was not integrated with that of a dentist. Traditional healers have special qualities that make them highly effective in primary oral health care therefore making them inevitable stakeholders in primary oral health care delivery. The research gaps in this review include the integration of traditional medicine into the oral health care systems of many African countries and the evaluation of the treatment outcomes of traditional medicine in dental care.

Traditional medicine use and the anaesthetist

This review considers traditional medicine, with an emphasis on traditional African medicine and its influence on perioperative care. Western and Eastern herbal remedies are widely used. The paucity of good quality evidence concerning these medicinal products has led to only some of the effects of these medicines being known. The wide range of preparatory methods and lack of regulation has resulted in patient exposure to unknown side-effects. The nature of the use of African traditional medicine is even less known, and probably disclosed to the Western health practitioner even less. This review aims to raise awareness of African traditional medicine healthcare practice and its implications in a perioperative population.

A cross-sectional analytical study of geophagia practices and blood metal concentrations in pregnant women in Johannesburg, South Africa.

Geophagia, a form of pica, has been shown to be widely practised in sub-Saharan Africa, especially among pregnant women. To assess the prevalence of geophagia and examine exposure to selected metals and associated risk factors in women attending an antenatal clinic at Rahima Moosa Mother and Child Hospital, Johannesburg, South Africa, during June and July 2010. We conducted a cross-sectional study on a convenience sample of 307 pregnant women, ranging in age from 18 to 46 years. Structured interviews were conducted to understand geophagia practices. Blood samples were collected to determine haemoglobin values and concentrations of arsenic, cadmium, mercury and lead. Statistical analyses using the χ2 test, Wilcoxon's rank-sum test and logistic regression analyses were performed as appropriate. Mean parity was 1.4 and the mean (standard deviation) gestational age 30.3 (6.0) weeks. Geophagia was reported by 60 women (19.5%), and the majority purchased soil from street vendors (83.3%). The prevalence of anaemia in the study sample was 16.9% (95% confidence interval 13.1 - 21.6%). Geophagic women had significantly higher blood lead levels than non-geophagic women (2.1 v. 1.4 µg/dl; p<0.001). Anaemia, the use of African traditional medicines and craving of non-nutritive substances in a previous pregnancy were associated with geophagia. Geophagia is practised by a considerable proportion of pregnant women in Johannesburg, especially migrant women. Greater vigilance in respect of pica, especially geophagia, may be needed as part of antenatal care programmes to avoid potentially detrimental health effects of the practice.

Health and wellness in Southern Africa: Incorporating indigenous and western healing practices

Current healing systems in Southern Africa focus on the holistic approach to the health and wellness of patients. Biomedical approaches and traditional healing systems that incorporate spiritual healing, mental healing, physical and social healing play a crucial and significant role in health delivery systems in Southern Africa. An integrative approach has been accepted as a vital component of holistic healing. Often, biomedicine has been criticized for overlooking the relationship of the social and spiritual being to the body and the effect the former has on the latter. Medicine and healing are cultural practices; hence the process of healing and the interpretation of illness reflect and reinforce the cultural definitions of the health problem. Biomedical technology often determines what is to be taken as authoritative knowledge and, in turn, establishes a particular domain of power. Biomedicine typically extends this privileged position to economics, politics, and class relationships. While the situation of traditional medicine appears to remain weak and marginalized. effort is being made in most African countries to integrate biomedicine and alternative healing paradigms. This paper explores the influence of traditional beliefs and practices and the use of African traditional medicine in the healing process. It further discusses the integration of indigenous healing systems and western medical approaches. The paper concludes that where both biomedical practices and traditional healing systems exist, patients should have a choice of the healing approach and process they prefer, the former or the latter, or a combination of both. Key words: Biomedicine, culture, traditional medicine, holistic approach, western medicine.

ETHICAL AND REGULATORY ISSUES SURROUNDING AFRICAN TRADITIONAL MEDICINE IN THE CONTEXT OF HIV/AIDS

It has been estimated that more than 80% of people in Africa use traditional medicine (TM). With the HIV/AIDS epidemic claiming many lives in Africa, the majority of people affected rely on TM mainly because it is relatively affordable and available to the poor populations who cannot afford orthodox medicine. Whereas orthodox medicine is practiced under stringent regulations and ethical guidelines emanating from The Nuremburg Code, African TM seems to be exempt from such scrutiny. Although recently there have been calls for TM to be incorporated into the health care system, less emphasis has been placed on ethical and regulatory issues. In this paper, an overview of the use of African TM in general, and for HIV/AIDS in particular, is given, followed by a look at: (i) the relative laxity in the application of ethical standards and regulatory requirements with regards to TM; (ii) the importance of research on TM in order to improve and demystify its therapeutic qualities; (iii) the need to tailor-make intellectual property laws to protect traditional knowledge and biodiversity. A framework of partnerships involving traditional healers' associations, scientists, policy makers, patients, community leaders, members of the communities, and funding organizations is suggested as a possible method to tackle these issues. It is hoped that this paper will stimulate objective and constructive debate that could enhance the protection of patients' welfare.