Health Urgency Research Articles

“Let’s say it wears an Ebola Coat, but it’s not Ebola”: The Rhetoric and Politics of Reframing a Vaccine for a Transnational Clinical Trial

Focusing on how disease, health and vaccine research take on different forms, meanings and interpretations in diverse contexts, we examine the use of rhetoric to recruit people living with HIV in sub-Saharan Africa for an Ebola vaccine clinical trial. Conducted after the West African Ebola outbreak in a country that had not been affected by Ebola, the urgency, relevance and materiality of disease, health and biomedical research takes on different shapes, meanings and understandings. The limitations of multilateral initiatives to address inequalities in associated healthcare and access to essential medicines and vaccines highlight the tensions created when neither local researchers nor patient communities have been involved in the design or planning of the trial, and when the pathologies targeted by experimental technologies are either inappropriate for the people they are aimed at, or unfold without the knowledge of a social consensus. By deciphering the metaphorical discourse on an Ebola vaccine candidate and the erasure of a viral ontology from the hybrid technology to which it gives rise, we understand that the discourse of clinic staff makes it possible to establish a scientific truth in the service of instrumental productivity: manufacturing consent and recruiting arms for vaccine shots. In this article, we show that the closure of biomedicine to an esoteric discourse reflects the weakness of science in communicating what it actually does and the techniques it produces. It also addresses the failure of community engagement in the field of emerging infectious diseases.

Healthy city development: Indonesian government plans to build a new capital city

The urgency of urban health in Indonesia is very worrying because most of Indonesia’s population now lives in urban areas with minimal supporting infrastructure. That prompted this study to analyze the government’s response to the healthy city development plan in the new capital city. This study uses a qualitative approach that focuses on thematic analysis. It helps check official government documents related to healthy city development plans. The relevant documents that were found were in the form of regulations. This regulation is Law of the Republic of Indonesia Number 3 of 2022 concerning the National Capital (Ibu Kota Negara, IKN). This official document was coded by maximizing the analysis tool, namely NVivo 12 Plus. This study succeeded in mapping several bare references in the healthy city development plan for the new capital city by the Indonesian government. Some of these primary references include the healthy city model (World Health Organization, WHO), the healthy city strategy (Cardiff), and (Vancouver). All of these primary references aim to improve the quality of life of residents in cities through city development that focuses on health. However, there are several challenges that the Indonesian government may face in the future, including problems with air pollution, environmentally friendly transportation, and the provision of green public spaces, health facilities, universal health services, and other infrastructure. This all requires adequate capacity and budget plans, including ensuring transparency in budget management. This study also encourages collaboration between the government, the private sector, and civil society to support the development of healthy cities that run well and sustainably.

Emerging global trends in next-generation alternatives to classic antibiotics for combatting multidrug-resistant bacteria

The issue of antibiotic resistance by pathogenic bacteria is considered one of the major global threats to current public health. The need to find solutions to this problem is driving the development of new therapies as alternatives to the use of conventional antibiotics. For this reason, the number of research studies and published works on this topic has increased significantly in recent years. The present study aims to analyze global scientific production data regarding the development of new therapies as alternatives to the use of conventional antibiotics, with the goal of determining the latest trends in the field and facilitating the creation of effective alternatives. A total of 47,702 studies have been published in just 13 years (2010–2023), a massive quantity surpassed only by research related to the recent COVID-19 pandemic, demonstrating the current state of health urgency. The United States and China lead the research efforts in terms of institutions, authors, and journals, demonstrating intense collaboration between two of the world's leading economic powers. Antimicrobial peptides (AMPs), nanotechnology, plant-based methods, phage therapy, probiotics, vaccines, or antibodies are being more extensively investigated compared to other more novel alternatives including bacteriocins and CRISPR-based therapies. Our results indicate that most of the studied alternatives are used in combination to enhance treatment efficacy. Specifically, many of them are focused on preventing the development of biofilms, which appear as the primary virulence agent of resistant pathogenic bacteria. Our results provide new data that may help in the search for novel alternatives or in improving current treatments for the development of an effective solution. In addition, our data can also be of great assistance in promoting international collaboration between countries and institutions with greater experience in the field.

Teaming up to overcome challenges toward translation of new therapeutics for osteoarthritis.

As a leading global cause of musculoskeletal-related disability, osteoarthritis (OA) represents a public health urgency. Understanding of disease pathogenesis has advanced substantially in the past decade, yet no disease-modifying therapeutics have advanced to the clinic. To address this challenge, the CARE-AP (Cartilage Repair strategies to alleviate Arthritis Pain) collaborative research team was convened to bring together relevant multidisciplinary expertise and perspectives from across the VA research community nationwide. The first CARE-AP Annual Research Symposium took place (virtually) in February 2022 with roughly 90 participants. A number of innovative and therapeutic strategies were discussed, including siRNA approaches coupled with novel nanoparticle-based delivery systems, cellular engineering approaches to develop reparative cells that can probe the joint environment and respond to disease-specific cues, and novel biofabrication techniques to improve tissue engineering and effect "biological joint replacement." In addition, challenges and advances in rehabilitation approaches, imaging outcomes, and clinical studies were presented, which were integrated into a framework of recommendations for running "preclinical trials" to improve successful clinical translation.

Adapted vaccine strategy: facing the persistent challenges of COVID-19

Adapted vaccine strategy: facing the persistent challenges of COVID-19

New Frontiers in Diagnosis and Prevention of Acute Kidney Injury (AKI): The Role of Dendritic Cells and Innovative High-Throughput Techniques

Kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD), represent a general, public health urgency, causing a heavy burden to global health care systems. Moreover, AKI is a frequent complication of hospitalization, and it is associated with short-term morbidity and mortality rate greater than 50%, as a result of its relationship with other severe complications. Furthermore, multiple pathophysiologic processes are involved in AKI, such as cellular death, apoptosis, mesenchymal transition, cellular infiltration, inflammation, cytokines release, coagulation, and complement activation. Since increasing evidence highlighted the central role of the immune system in AKI pathophysiology, several efforts have been made to delineate the link between this disease and the different population of immune cells. This narrative review aims to describe the role played by dendritic cells (DCs) in AKI, with a special focus on recent findings suggesting DCs suppression as a promising strategy to prevent AKI negative side effects and ameliorate renal injury and dysfunction. Furthermore, we briefly summarize the main characteristics of innovative high-throughput techniques, including as genomics, transcriptomics, proteomics, and metabolomics in the context of AKI.

Prevalence and influencing factors of self-medication during the COVID-19 pandemic in the Arab region: a multinational cross-sectional study

BackgroundThe novel coronavirus pandemic (COVID-19) has begun with a wave of misinformation and fear of infection. This may have led people to self-medicate inappropriately. The World Health Organization describes self-medication (SM) as utilizing medicines to relieve symptoms or health conditions without consulting a physician. Inappropriate drug use is a burden on both health resources and patient health in the Arab region. This study aimed to detect the prevalence and influencing factors of self-medication among the general Arab population during the COVID-19 pandemic.MethodsA multinational cross-sectional study was conducted among the general population of ten Arab countries from early August to late October 2021. Participants aged 18 years or older could join the study via social media platforms. A convenience sampling technique was used. A developed and validated web-based questionnaire was used to collect data on self-medication practice, associated influencing factors, information sources, commonly used medications, and commonly treated conditions. Descriptive, univariate, and multivariate regression analyses were applied using IBM SPSS v 26 and R v 4.0.0 software.ResultsA total of 8163 participants completed the questionnaire, and 518 participants were excluded from the analysis due to inconsistencies in their data. Almost two-thirds (62.7%) of participants reported practicing self-medication during the COVID-19 pandemic. At the country level, Egypt had the highest prevalence of self-medication practice (72.1%), while Palestine had the lowest prevalence (40.4%). The most commonly used drugs were analgesics, antipyretics, and vitamins (86, 65.1, and 57.1%, respectively), while antitussives and antibiotics scored 47.6 and 43.3%, respectively. Experience with similar health conditions (74.6%) and urgency of the problem (47.2%) were the most frequent factors that led to self-medication. Additionally, 38.2% of the self-medicated participants (SMPs) used drugs as prophylaxis against COVID-19. Pharmacist consultation was the most common source of information about self-medication (66.7%). Multivariate analysis showed that predictors of self-medication were older age (p = 0.008), presence of chronic illness (p = 0.015), and having monthly income or medical insurance that does not cover the treatment cost (p = 0.001, p < 0.001, respectively).ConclusionSelf-medication is considered a common practice across the Arab population. It is necessary to regulate policies and raise awareness among the public about self-medication.

A Novel Inpatient Buprenorphine Induction Program for Adolescents With Opioid Use Disorder.

Morbidity and mortality from nonprescribed opioid use and opioid use disorder (OUD) in adolescents have risen dramatically. Medication for opioid use disorder (MOUD) with buprenorphine reduces nonprescribed opioid use and prevents overdoses, though <5% of adolescents with OUD have timely access, partly because of barriers associated with buprenorphine induction. Induction in an inpatient pediatric setting has the potential to address such barriers and improve adolescent MOUD access. We developed and implemented a protocol for inpatient buprenorphine induction and linkage to MOUD care within a safety-net health system. After 1 year, we conducted descriptive analysis of participant characteristics, rates of induction completion and treatment linkage, and adverse events. We analyzed field notes from multidisciplinary huddles to identify implementation facilitators and barriers. During May 2021 to July 2022, we completed 46 admissions for 36 patients aged 12 to 21 years. All used fentanyl and no other opioids. Forty of 46 (87%) admissions resulted in completed induction, and 3 additional patients never developed withdrawal symptoms and were discharged with maintenance buprenorphine. Linkage to ongoing treatment occurred within 2 weeks for 31 of 43 (72%) admissions for which buprenorphine was started. We identified facilitators and barriers to program implementation and maintenance. These results provide promising preliminary evidence of the feasibility of inpatient buprenorphine induction for adolescents with OUD. Given the public health urgency and severe shortage of adolescent access to MOUD, these results prompt consideration of broader clinical implementation and research to facilitate rapid expansion of access to evidence-based OUD care.

Short Communication: Kajian Etik, Kesejahteraan, dan Kesehatan Hewan dalam Fenomena Topeng Monyet

The phenomenon of dancing monkeys is a cultural and traditional art in Indonesia by exploiting primates, especially the Macaca fascicularis or long-tailed macaque species. Law enforcement efforts related to the dancing monkey phenomenon seem biased. Apart from the fact that the long-tailed macaque is one of the unprotected animals, there is also no strict enforcement of existing laws, although they can often be charged with animal health and welfare regulations. This study discusses the urgency of ethics, animal welfare, and health in primates who used dancing monkeys as objects. The method used is a descriptive-qualitative approach based on the relevant scientific literature. There is still very little research related to the dancing monkey phenomenon, both in terms of ethics, animal welfare, and health, the urgency and further recommendations from the results of this study can be used to encourage efforts to prevent the dancing monkey phenomenon in the community by providing suggestions that can be applied to the community such as education, development of informative media, management of educative tourism objects based on wildlife and ecotourism, and participating in volunteering for animal observers or animal welfare in Indonesia.

COVID-19: epidemiological data of 1263 patients from southern Minas Gerais, Brazil

Background: COVID-19 is an easily contagious and high-speed viral disease that is directly affecting people's lives and exposing the fragility of health systems around the world, especially in Brazil. In this context, the present research sought to observe, through medical records, the conduct of positive patients with COVID-19.Methods: The methodology used was the analysis of medical records of patients with COVID-19 in five hospitals in Minas Gerais. The following data were collected from patients who were hospitalized from March 2020 to October 2020: personal characteristics; pathological antecedents and evolution of the clinical picture.Results: The results found describe the number of patients in each of the analysed hospitals. In addition, the predominant age, the sex of the patients in percentage, the number of patients with subarachnoid hemorrhage (SAH), chronic obstructive pulmonary disease (COPD), diabetes, dyslipidemia, altered D-dimer, anemia and hematologic change are described. Intensive care unit (ICU) and ward admissions are also addressed, as well as the type of respiratory complication, percentage of individuals who required intubation, intubation time and outcome. The results were used in statistical analysis for the association between variables with the Chi-square test to verify the significance between them. The outcome was compared with age, sex, diabetes, dyslipidemia, D-dimer biomarker, anemia, hematological changes and type of hospitalization. With the type of hospitalization, diabetes and dyslipidemia were compared.Conclusions: Faced with all this context of public health urgency, this work helps in the standardization of variables to collaborate in the fight against this giant and persistent virus that public health is trying to fight.

Time to Revise the WHO Categories for Severe Rabies Virus Exposures-Category IV?

Rabies is a devastating disease and affects millions of people globally, yet it is preventable with appropriate and timely postexposure prophylaxis (PEP). The current WHO exposure categories (Categories I, II, and III) need revision, with a special Category IV for severe exposures. Rare cases of PEP failure have occurred in severe bites to the head and neck. Multiple factors, including route, wound severity, depth, contamination, viral dose, proximity to highly innervated areas and the CNS, and the number of lesions, remain unconsidered. Injuries in areas of high neural density are the most significant considering lyssavirus pathophysiology. Current recommendations do not account for these factors. A Category IV designation would acknowledge the severity and the increased risk of progression. Subsequently, patient management would be optimized with wound care and the appropriate administration of rabies-immune globulin/monoclonal antibodies (RIG/MAbs). All Category IV exposures would be infiltrated with the full dose of intact RIG (i.e., human RIG or MAbs) if the patient was previously unvaccinated. More concentrated RIG/MAb formulations would be preferred. As a world rabies community, we cannot tolerate PEP failures. A fourth WHO categorization will improve the care of these high-risk patients and highlight the global health urgency of this neglected disease.

Prevalence of multimorbidity and its correlates among older adults in Eastern Nepal

BackgroundThe number of people with multimorbidity is surging around the world. Although multimorbidity has been introduced in policy and practice in developed countries, developing countries like Nepal have not considered it as a matter of public health urgency due to the lack of enough epidemiological data. Multimorbidity profoundly affects older adults’ wellbeing; therefore, it is crucial to estimate its prevalence and determinants. This study aimed to estimate the prevalence of multimorbidity among older adults in Eastern Nepal and identify its correlates.MethodologyA community-based cross-sectional survey was conducted in three districts of Eastern Nepal. Data were collected between July and September 2020, among 847 Nepali older adults, aged 60 and older, where study participants were recruited through a multi-stage cluster sampling technique. Semi-structured interviews were conducted at the community settings to collect data. Logistic regression assessed correlates of multimorbidity. SAS 9.4 was used to run all statistical tests and analyses.ResultsMore than half (66.5%) of the participants had at least one of the five non-communicable chronic conditions; hypertension (31.6%), osteoarthritis (28.6%), chronic respiratory disease (18.0%), diabetes (13.5%), and heart disease (5.3%). The prevalence of multimorbidity was 22.8%. In the adjusted model, increased age (for 70–79 years, OR: 3.11, 95% CI: 1.87–5.18; for 80 + years, OR: 4.19, 95% CI: 2.32–7.57), those without a partner (OR: 1.52, 95% CI: 1.00–2.30), residing in urban areas (OR: 1.71, 95% CI: 1.16–2.51), and distant from health center (OR: 1.66, 95% CI: 1.04–2.64) were significantly associated with multimorbidity.ConclusionsThis study found one in five study participants had multimorbidity. The findings will assist policymakers and stakeholders in understanding the burden of multimorbidity among the older population and identifying the groups in most need of health promotion intervention. Future interventions may include developing horizontal multimorbid approaches and multisectoral strategies specifically tailored to meet the needs of those populations.

A Strategic Framework for Community Engagement in Oceans and Human Health.

Over the past two decades, scientific research on the connections between the health and resilience of marine ecosystems, and human health, well-being, and community prosperity has expanded and evolved into a distinct "metadiscipline" known as Oceans and Human Health (OHH), recognized by the scientific community as well as policy makers. OHH goals are diverse, and seek to improve public health outcomes, promote sustainable use of aquatic systems and resources, and strengthen community resilience. OHH research has historically included some level of community outreach and partner involvement; however, the increasing disruption of aquatic environments and urgency of public health impacts calls for a more systematic approach to effectively identify and engage with community partners to achieve project goals and outcomes. Herein, we present a strategic framework developed collaboratively by community engagement personnel from the four recently established U.S. Centers for Oceans and Human Health (COHH). This framework supports researchers in defining levels of community engagement and in aligning partners, purpose, activities, and approaches intentionally in their community engagement efforts. Specifically, we describe: (1) a framework for a range of outreach and engagement approaches; (2) the need for identifying partners, purpose, activities, and approaches; and (3) the importance of making intentional alignment among them. Misalignment across these dimensions may lead to wasting time or resources, eroding public trust, or failing to achieve intended outcomes. We illustrate the framework with examples from current COHH case studies, and conclude with future directions for strategic community engagement in OHH and other environmental health contexts.

Successful management report of COVID-19 with unusual symptoms after heart surgery

COVID-19 is a pandemic and general health urgency with global concern which is rapidly spreading with the new sign. A 72-years-old man with diagnosis of myocardial infarction is transferred to the operating room for the coronary artery bypass surgery. The coronavirus-2019 test and the other diagnostic methods related to it were done and the result was negative. He returned to the hospital with hypotension two months after surgery. At first, the surgeon thought that these symptoms were related to the side effects of the cardiac medicines, so stopped taking and decreased the dose of those medicines. However, the hypotension persisted while the patient complained of anorexia, dizziness, and nausea. Considering the fact that the patient’s daughter was a health care worker who suffered from COVID-19, chest High-Resolution CT (HRCT) was conducted showing multi-focal peripheral consolidations in both lungs purposing viral pneumonia. Consequently, the patient was isolated. COVID-19 Polymerase Chain Reaction (PCR) was cheeked, which turned out to be positive and confirmed the diagnosis. Patients received intensive care in the hospital for six days and were discharged in good general condition to pass the rest of the isolation period at home. It is recommended according to the common symptoms of the coronavirus-2019 disease and the side effects of the cardiac patients’ medicines, such as vertigo, nausea, and vomiting, that these symptoms, in the case of these symptoms’ occurrence for the patients of coronary artery bypass surgery, can be resulted from the coronavirus-2019 disease, not from the medicine effects.

To the understanding of public health systems in Ukraine

The scientific article is devoted to the study of an important issue of public health in Ukraine. Today, the nation's health is a priority in the field of health care, both in terms of funding and regulation. This situation is due primarily to the COVID-19 pandemic. The paper defines the concept of "public health" and its normative guidelines. The legislation in the field of health care in terms of ensuring the functioning of the public health system is analyzed. Public health is seen as a system of measures aimed at preventing disease, physical and psychological conditions, increasing life expectancy and quality of life through epidemiological surveillance of health indicators. The factors that determine the urgency of public health at the present stage of development of Ukraine are outlined. Emphasis is placed on epidemiological surveillance as a component of public health, on disease prevention. The article considers health risks as the probability of adverse health effects (including death) that occur in the presence of factors of physical, biological or any other origin, including of unknown nature. proposals for priority steps in the systematic update of public health regulations have been made. Such regulation should take into account the experience of combating COVID-19 on the ability to monitor indicators and risks to public health at both national and international levels; on public health emergencies. And this should be done with an emphasis on the competencies of public authorities in the field of public health. Public health should be a priority in the implementation of health policy, which will reduce the burden on the public health system in the long run.

Making Connections to Improve Health Outcomes.

This issue of Global Advances in Health and Medicine sends a vital message about the importance of whole person health. Whole person health rests on the idea that our health involves multiple interconnected factors across physiological systems, as well as biological, behavioral, social, and environmental domains. The urgency of better understanding whole person health is highlighted by the current global health crisis. Yet, biomedical research often favors a reductionist approach. The current emphasis on diseases or single organ systems can fall short when it comes to addressing the interconnected factors that contribute to worse health outcomes. This, coupled with a fragmented health care delivery system, contributes to the challenges that patients face every day in becoming healthier. As part of the U.S. National Institutes of Health, our role at the National Center for Complementary and Integrative Health (NCCIH) is to foster research in this field. NCCIH’s twenty years of research has built a body of knowledge that has established a clear path forward for exploring whole person health in the coming years. Within the framework of our strategic plan, NCCIH is working to build research methods for studying whole person health and explore how this understanding of health can transform the way complementary and integrative health is perceived and implemented within the wider health care delivery system.The collection of papers highlighted in this month’s issue of Global Advances in Health and Medicine sends an important and encouraging signal about the efforts being made to deliver health care in a way that recognizes the importance of whole person health. Each of these studies provides new insights on how stakeholders might approach transforming the delivery of health care, integrating approaches that can improve health outcomes for people.

URGENCY OF HEALTH IN INCREASING INCOME FAMILY IN THE TIME OF COVID-19

The purpose of this research activity regarding the urgency of health in increasing family income in the Covid-19 mass was carried out to provide awareness and awareness to the public, that there is a correlation between health and increasing family income amid of COVID-19. The objects in this research activity were 20 people from the Harapan Jaya HKm Batu Ampar group at the Pasaman Raya orphanage. In this activity, the method used is in-depth interviews involving all objects that have been defined. The results of this study are the object in this study that understands and understands the causality between increasing family income and the health condition experienced. Increased family income will be in line with health that is always maintained, both in terms of food consumption, self-sterilization when going out of the house, and so on. When health is maintained, self-mobility will also be high which will have a positive impact on increasing family income

Social Determinants of Suboptimal Cardiovascular Health Among Pregnant Women in the United States.

BackgroundSuboptimal cardiovascular health (CVH) and social determinants of health (SDOH) have a significant impact on maternal morbidity and mortality. We aimed to evaluate the association of SDOH with suboptimal CVH among pregnant women in the United States.Methods and ResultsWe examined cross‐sectional data of pregnant women aged 18 to 49 years from the National Health Interview Survey (2013–2017). We ascertained optimal and suboptimal CVH based on the presence of 0 to 1 and ≥2 risk factors (hypertension, diabetes, hyperlipidemia, current smoking, obesity, and insufficient physical activity), respectively. We calculated an aggregate SDOH score representing 38 variables from 6 domains (economic stability; neighborhood, physical environment, and social cohesion; community and social context; food; education; and healthcare system) and divided into quartiles. We used Poisson regression model to evaluate the association of SDOH with suboptimal CVH and risk factors. Our study included 1433 pregnant women (28.8±5.5 years, 13% non‐Hispanic Black). Overall, 38.4% (95% CI, 33.9–43.0) had suboptimal CVH versus 51.7% (95% CI, 47.0–56.3) among those in the fourth SDOH quartile. Risk ratios of suboptimal CVH, smoking, obesity, and insufficient physical activity were 2.05 (95% CI, 1.46–2.88), 8.37 (95% CI, 3.00–23.43), 1.54 (95% CI, 1.17–2.03), and 1.19 (95% CI, 1.01–1.42), respectively among those in the fourth SDOH quartile compared with the first quartile.ConclusionsOver 50% of pregnant women with the highest SDOH burden had suboptimal CVH, highlighting the public health urgency for interventions in socially disadvantaged pregnant women with renewed strategies toward improving modifiable risk factors, especially smoking and insufficient physical activity.

KEEPING THE BODY IMMUNE IN ISLAMIC PERSPECTIVE IN PANDEMIC TIMES

This research is about maintaining the body's immunity from an islamic perspective during a pandemic. Health is a very attentive thing in Islam, so Islam recommends that you always be able to maintain health so that your body's immune or immune system can stay better and stay strong. This library research aims to understand the urgency of health in Islam and maintain immunity in Islam. This study uses a descriptive method by describing the information in the relevant library materials. The data collection technique in this study is a documentary technique. Namely, information is extracted through documents from various library materials. It is analyzed using content analysis, namely, examining the object of discussion through analysis of books, essays, magazines, articles, and all forms of communication that can be analyzed. The results of this study indicate that the body's immunity or immunity in Islam is adequate rest, eating halal and good food and not excessive (in moderation), and regular exercise. Apart from adequate rest, adequate nutrition, and regular exercise. It is also recommended to maintain mental health, which of course, influences on increasing one's immunity or immunity by constantly reading the Qur'an, praying, and remembering Allah.

The Food Equity and Environmental Data Sovereignty (FEEDS) Project: Protocol for a Quasi-Experimental Study Evaluating a Digital Platform for Climate Change Preparedness.

BackgroundDespite having the tools at our disposal to enable an adequate food supply for all people, inequities in food acquisition, distribution, and most importantly, food sovereignty, worsen food insecurity. The detrimental impact of climate change on food systems and mental health is further exacerbated by a lack of food sovereignty. We urgently require innovative solutions to enable food sovereignty, minimize food insecurity, and address climate change–related mental distress (ie, solastalgia). Indigenous communities have a wealth of Traditional Knowledge for climate change adaptation and preparedness to strengthen food systems. Traditional Knowledge combined with Western methods can revolutionize ethical data collection, engagement, and knowledge mobilization.ObjectiveThe Food Equity and Environmental Data Sovereignty (FEEDS) Project takes a participatory action, citizen science approach for early detection and warning of climate change impacts on food sovereignty, food security, and solastalgia. The aim of this project is to develop and implement a sustainable digital platform that enables real-time decision-making to mitigate climate change–related impacts on food systems and mental well-being.MethodsCitizen science enables citizens to actively contribute to all aspects of the research process. The FEEDS Project is being implemented in five phases: participatory project planning, digital climate change platform customization, community-led evaluation, digital platform and project refinement, and integrated knowledge translation. The project is governed by a Citizen Scientist Advisory Council comprising Elders, Traditional Knowledge Keepers, key community decision makers, youth, and FEEDS Project researchers. The Council governs all phases of the project, including coconceptualizing a climate change platform, which consists of a smartphone app and a digital decision-making dashboard. Apart from capturing environmental and health-related big data (eg, weather, permafrost degradation, fire hazards, and human movement), the custom-built app uses artificial intelligence to engage and enable citizens to report on environmental hazards, changes in biodiversity or wildlife, and related food and mental health issues in their communities. The app provides citizens with valuable information to mitigate health-related risks and relays big data in real time to a digital dashboard.ResultsThis project is currently in phase 1, with the subarctic Métis jurisdiction of Île-à-la-Crosse, Saskatchewan, Canada.ConclusionsThe FEEDS Project facilitates Indigenous Peoples’ self-determination, governance, and data sovereignty. All citizen data are anonymous and encrypted, and communities have ownership, access, control, and possession of their data. The digital dashboard system provides decision makers with real-time data, thereby increasing the capacity to self-govern. The participatory action research approach, combined with digital citizen science, advances the cocreation of knowledge and multidisciplinary collaboration in the digital age. Given the urgency of climate change, leveraging technology provides communities with tools to respond to existing and emerging crises in a timely manner, as well as scientific evidence regarding the urgency of current health and environmental issues.International Registered Report Identifier (IRRID)PRR1-10.2196/31389