Ureteral Pseudodiverticulosis Research Articles

Bilateral Pyelonephritis in a Cat with Multiple Urinary Malformations Including Ureteral Pseudodiverticulosis

Ureteral pseudodiverticulosis is an unusual acquired abnormality in humans and dogs. This report describes the first feline case of ureteral pseudodiverticulosis, associated with right retrocaval ureter and malposition of the uretero-vesical junctions, in the context of pyelonephritis. The coexistence of pseudodiverticulosis with other urinary abnormalities suggested that this lesion should be considered in other patients with urinary pathology.

Commentary: Ureteral pseudodiverticulosis is diagnosable on computed tomography.

Commentary: Ureteral pseudodiverticulosis is diagnosable on computed tomography.

Diagnostic imaging characteristics of ureteral pseudodiverticulosis in three dogs

Ureteral pseudodiverticulosis is rarely reported in veterinary medicine. This case study aimed to describe the radiographic, ultrasonographic and computed tomographic findings for dogs with radiologically confirmed ureteral pseudodiverticulosis. Three dogs met the inclusion criteria. Radiographic findings included multiple small, round-shaped mineral opacities located around the periphery of the ureters (3/3), and multiple contrast medium-filled outpouchings that appeared and disappeared when the contrast medium washed in and out on intravenous excretory urography (2/3). The outpouchings were approximately 1 mm in diameter. In the ultrasonographic images, the mineral foci were located adjacent to the ureter, but not within the ureteral lumen (1/3). Contrast-enhanced CT findings were similar to those of excretory urography (2/3). Ureteral pseudodiverticulosis should be considered in the differential diagnosis for old-aged and small-breed dogs with radiopaque materials along the ureteral pathways; excretory urography or contrast-enhanced CT are recommended for a more definitive imaging diagnosis.

Ureteral pseudodiverticulosis and urothelial cell carcinoma: rethinking the association.

To compare frequency of new and recurrent urothelial cell carcinoma (UCC) among patients with and without pseudodiverticulosis on imaging. This retrospective case-control study compared all 113 sequential patients with ureteral pseudodiverticulosis on radiographic urography between 1/1/2002 and 12/31/2012. Six patients were lost to follow-up. 107 patients without pseudodiverticulosis were matched by imaging modality, clinical indication, and tumor grade. Known UCC and primary outcome of new or recurrent UCC were determined through pathology on cystoscopy or clinical follow-up. Nearly half of patients with pseudodiverticulosis had known UCC at the time of imaging (49/107, 46%). Mean cystoscopy follow-up was 7.0 and 4.6years for pseudodiverticulosis cases with and without known UCC, respectively, and 7.5 and 7.3years for controls, respectively. Mean clinic follow-up was 7.5 and 6.0years for pseudodiverticulosis cases with and without known UCC, respectively, and 6.4 and 7.6years for controls, respectively. Among patients with known UCC at the time of imaging, similar rates of recurrent UCC were demonstrated on follow-up among patients with pseudodiverticulosis (6/49, 12%) and without (7/49, 14%). Among patients with no known history of UCC at the time of imaging, no patients with pseudodiverticulosis developed UCC on follow-up and 5% (3/58) of patients without pseudodiverticulosis developed UCC. Although half of patients with ureteral pseudodiverticulosis have a known diagnosis of UCC, the presence of pseudodiverticulosis did not signify an increased likelihood of developing new or recurrent UCC over the follow-up period.

Ureteral Pseudodiverticulosis

Presented is a case of ureteral pseudodiverticulosis diagnosed by multidetector computed tomography (CT). Axial and coronal reformatted CT images revealed multiple small (2-4 mm) outpouchings of both ureters, characteristic of ureteral pseudodiverticulosis. The unenhanced CT also revealed a 6-mm stone at the left ureterovesical junction and a high attenuation lesion at the right ureterovesical junction suspect for an associated uroepithelial neoplasm.

Pseudodiverticulosis uretral: A propósito de un caso

To report a new case of bilateral ureteral pseudodiverticulosis associated with a transitional cell carcinoma of the bladder.70 year-old male patient under ambulatory study for hematuria.The intravenous urography (IVU) shows images of addition in relation to bilateral ureteral pseudodiverticulosis. Urine cytology and cystoscopy showed the existence of a concomitant tumor.The diagnosis of ureteral pseudodiverticulosis is incidentally made on an IVU indicated for other reasons. Although it is a benign pathology, it is necessary to follow these patients because of its association with transitional cell carcinoma.

Ureteral pseudodiverticulosis: The case for the retrograde urogram

Ureteral pseudodiverticula are small outpouchings along the length of the ureter diagnosed primarily by the retrograde urogram. They are associated with hematuria and urinary tract infections, although it is not known whether they cause these associated symptoms or are a result of them. Herein we report 2 cases that highlight the characteristic clinical correlates of ureteral pseudodiverticulosis and review the pertinent literature.

Pseudodiverticulosis: unusual appearance for metastases to the ureter.

A rare pseudodiverticular pattern of metastatic malignancy to the ureter is reported along with pathologic findings at postmortem examination in three patients. There was no clinical or pathological obstruction. This pattern is due to malignancy-induced edema in the subepithelial connective tissues and muscularis propria causing displacement of these layers into the ureteral lumen resulting in an undulating epithelial surface. The epithelium itself is normal. Metastases to the ureter is uncommon in life unless associated with ureteral obstruction. Ureteral pseudodiverticulosis found in vivo in a nonobstructed patient with known metastatic malignancy is likely due to inflammatory causes and usually reversible with antibiotic and medical therapy. A patient with widespread malignancy showing nonreversibility of the ureteral pseudodiverticular pattern, even in the absence of obstruction, should be considered a candidate for impending obstruction and followed closely for ureteral stent placement.

Ureteral pseudodiverticulosis.

There have been few reported cases of ureteral diverticula less than 4 mm in diameter; these are best described as pseudodiverticula based on their appearance in specimens obtained for pathologic study. An additional 23 patients are reported, 15 of whom were examined by urinalysis, urine culture, cystoscopy, and cytologic studies of the urine. Cytologic findings are of interest because of previous reports suggesting an association between ureteral diverticula and transitional cell carcinoma in the urinary tract. Hematuria, transitional cell carcinoma, and benign prostatic hyperplasia were the most common presenting conditions. Infection was found in only three. Diverticula were multiple in 91%, bilateral in 69%, and were predominantly upper and midureteral in location. Urine cytologic studies failed to detect early uroepithelial malignancy, but nonspecific cellular atypia and an association with malignancy in 30% of these patients suggests that close follow-up of patients with ureteral pseudodiverticulosis is prudent.