Unobserved Heterogeneity In Data Research Articles

A home-based approach to understanding seatbelt use in single-occupant vehicles in Tennessee: Application of a latent class binary logit model

Although the enforcement of seatbelt use is considered to be an effective strategy in reducing road injuries and fatalities, lack of seatbelt use still accounts for a substantial proportion of fatal crashes in Tennessee, United States. This problem has raised the need to better understand factors influencing seatbelt use. These factors may arise from spatial/temporal characteristics of a driving location, type of vehicle, demographic and socioeconomic attributes of the vehicle occupants, driver behaviours, attitudes, and social norms. However, the above factors may not have the same effects on seatbelt use across different individuals. In addition, the behavioural factors are usually difficult to measure and may not always be readily available. Meanwhile, residential locations of vehicle occupants have been shown to be associated with their behavioural patterns and thus may serve as a proxy for behavioural factors. However, the suitability of geographic and residential locations of vehicle occupants to understand the seatbelt use behaviour is not known to date.This study aims to fill the above gaps by incorporating the residential location characteristics of vehicle occupants in addition to their demographics and crash characteristics into their seatbelt use while accounting for the varying effects of these factors on individual seatbelt use choices. To achieve this goal, empirical data are collected for vehicular crashes in Tennessee, United States, and the home addresses of vehicle occupants at the time of the crash are geocoded and linked with the census tract information. The resulting data is then used as explanatory variables in a latent class binary logit model to investigate the determinants of vehicle occupants’ seatbelt use at the time of the crash. The latent class specification is employed to capture the unobserved heterogeneity in data. Results show that Tennessean drivers belong to two general categories—conformist and eccentric—with gender, vehicle type, and income per capita determining the likelihood of these categories. Overall, male drivers, younger drivers, and drivers who have consumed drugs are less likely to wear a seatbelt, whereas drivers who come from areas with higher population density, travel time, and income per capita are more likely to wear a seatbelt. In addition, driving during the day and in rainy weather are associated with an increased likelihood of seatbelt use. The findings of this study will help developing effective policies to increase seatbelt use rate and improve safety.

Evidence for overdispersion in the distribution of malaria parasites and leukocytes in thick blood smears

BackgroundMicroscopic examination of stained thick blood smears (TBS) is the gold standard for routine malaria diagnosis. Parasites and leukocytes are counted in a predetermined number of high power fields (HPFs). Data on parasite and leukocyte counts per HPF are of broad scientific value. However, in published studies, most of the information on parasite density (PD) is presented as summary statistics (e.g. PD per microlitre, prevalence, absolute/assumed white blood cell counts), but original data sets are not readily available. Besides, the number of parasites and the number of leukocytes per HPF are assumed to be Poisson-distributed. However, count data rarely fit the restrictive assumptions of the Poisson distribution. The violation of these assumptions commonly results in overdispersion. The objectives of this paper are to investigate and handle overdispersion in field-collected data.MethodsThe data comprise the records of three TBSs of 12-month-old children from a field study of Plasmodium falciparum malaria in Tori Bossito, Benin. All HPFs were examined systemically by visually scanning the film horizontally from edge to edge. The numbers of parasites and leukocytes per HPF were recorded and formed the first dataset on parasite and leukocyte counts per HPF. The full dataset is published in this study. Two sources of overdispersion in data are investigated: latent heterogeneity and spatial dependence. Unobserved heterogeneity in data is accounted for by considering more flexible models that allow for overdispersion. Of particular interest were the negative binomial model (NB) and mixture models. The dependent structure in data was modelled with hidden Markov models (HMMs).ResultsThe Poisson assumptions are inconsistent with parasite and leukocyte distributions per HPF. Among simple parametric models, the NB model is the closest to the unknown distribution that generates the data. On the basis of model selection criteria AIC and BIC, HMMs provided a better fit to data than mixtures. Ordinary pseudo-residuals confirmed the validity of HMMs.ConclusionFailure to take overdispersion into account in parasite and leukocyte counts may entail important misleading inferences when these data are related to other explanatory variables (malariometric or environmental). Its detection is therefore essential. In addition, an alternative PD estimation method that accounts for heterogeneity and spatial dependence should be seriously considered in epidemiological studies with field-collected parasite and leukocyte data.

Finite-Mixture Structural Equation Models for Response-Based Segmentation and Unobserved Heterogeneity

Finite-Mixture Structural Equation Models for Response-Based Segmentation and Unobserved Heterogeneity