The problem of channel estimation for multiple antenna orthogonal frequency division multiplexing (OFDM) systems subject to unknown carrier frequency offset (CFO) is addressed. Multiple signal classification (MUSIC)-like algorithm, which generally has been used for direction estimation or frequency estimation, is used for channel estimation in multiple antenna OFDM systems. A reduced dimensional (RD)-MUSIC based algorithm for channel estimation is proposed in multiple antenna OFDM systems with unknown CFO. The Cramér-Rao bound (CRB) of channel estimation in multiple antenna OFDM systems with unknown CFO is derived. The proposed algorithm has a superior performance of channel estimation compared with the Capon method and the least squares method.