University Hospital In Ankara Research Articles

Effect of Spirituality on Psychological Resilience and Hope in Patient-Family Caregiver Dyads Experiencing Gynecological Cancer: An Actor-Partner Interdependence Analysis.

Women experiencing gynecological cancer (GCPs) and family caregivers (FCGs) use spirituality to cope with cancer. However, the dual relationship between the impact of spirituality on psychological resilience and hope among both GCPs and FCGs has not yet been explored. To examine the interdependent relationship between spirituality, psychological resilience, and hope of women with gynecological cancer and their FCGs at the dyadic level. In this cross-sectional study, 107 dyads were recruited from the gynecological oncology departments of 2 university hospitals in Ankara, Turkey. The GCPs and FCGs completed a Patient/Family Caregiver Information Form, Spiritual Well-being Scale, Connor-Davidson Resilience Scale, and Dispositional Hope Scale. Data were analyzed using descriptive statistics and Pearson's correlations. This study used the Actor-Partner Interdependence Model. Spirituality of both GCPs and FCGs had a significant positive effect on their psychological resilience ( B = 0.918, P < .001; B = 0.435, P < .001, respectively) and hope ( B = 0.350, P < .001; B = 0.246, P < .001, respectively). However, the spirituality of GCPs and FCGs did not have a partner effect on psychological resilience ( B = -0.150, P < .052; B = -0.150, P = .052, respectively) and hope ( B = -0.012, P = .810; B = 0.073, P = .157, respectively). Spirituality of GCPs and their FCGs positively affected their psychological resilience and hope, but the effect on each other was limited. Health professionals, especially nurses, should focus on tailoring spiritual care interventions to the unique needs of each individual within the GCP and FCG dyads. Personalized approaches that recognize and address the specific spiritual concerns of patients and caregivers may be more effective in promoting psychological resilience and hope.

Evaluation of the Training Given to Emergency Department Nurses on Ventrogluteal Site Injection Administration: A Quasi-Experimental Study

Evidence-based data recommends injection to the ventrogluteal (VG) site instead of the dorsogluteal (DG) site for intramuscular injection (IMI) due to the risk of sciatic nerve damage. Despite this, it has been seen that nurses do not prefer this site due to insufficient information and negative opinions. The aim of this study was to determine how the training on administering an injection to the site provided to the nurses affects their knowledge, view and preference for the practice. The study design was a single-group, quasi-experimental pretest-posttest. The study was conducted with 30 nurses in the Adult Emergency Service of Hacettepe University Hospitals in Ankara, Turkey, between May and August 2020. The data was collected by using a nurse information form and forms that evaluated the nurses’ knowledge, opinions and practices regarding using the VG site. The data was analysed by using number, percentage, mean, standard deviation, Friedman test, Wilcoxon test, and McNemar test. As a result of the study, it was found that while the views of 86.7% (n = 26) of the nurses about the VG site changed positively after the training, the mean score of the VG site was 14.80+3.09 before the training, and 18.50+1.68 after the training (p &lt; .001). After the training, 7 of 16 nurses started to prefer the VG site for injection administration (p &gt; .05). The training provided on the VG site increased the knowledge of nurses, changed their views, and affected their preference for the practice. It is recommended that nurses repeat the training on IMI administration to the VG site and assess their abilities on a regular basis.

Calcineurin inhibitors in unplanned pregnancies with active lupus disease: A retrospective observational study.

To evaluate the use of calcineurin inhibitors (CNIs), specifically tacrolimus, in unplanned pregnancies with active lupus disease among patients with systemic lupus erythematosus (SLE). The study includes data from pregnancies in women diagnosed with SLE at Gazi University Hospital in Ankara, Türkiye, between January 2010 and July 2022. The study categorized pregnancies into planned and unplanned groups based on lupus nephritis presence, emphasizing the need for inactive lupus disease for at least 6 months before attempting conception in planned pregnancies. The outcomes of pregnancies involving CNIs, particularly tacrolimus, were assessed. In our cohort comprising 632 SLE patients, 39 individuals reported 42 pregnancies. Among the 42 pregnancies, 14 have a history of lupus nephritis. We observed that 8 of 14 patients with a history of lupus nephritis had unplanned pregnancies. Three patients used cyclosporine and 2 used tacrolimus during their pregnancy; their pregnancies were completely healthy, and no lupus flare was observed during their pregnancies. The pregnancy of 2 patients who used azathioprine and 1 last patient who used no immunosuppressive treatment ended in abortion. This study reveals that tacrolimus can be effectively used in unplanned pregnancies with active lupus disease, providing favorable maternal and fetal outcomes. The findings emphasize the importance of considering CNIs, particularly tacrolimus, in the management of SLE pregnancies, even in cases of unplanned pregnancies with a history of lupus nephritis.

Examination of Self-Care Behavior Profile and Self-Care Management in Hypertension Patients

Introduction: The main purpose of disease management in hypertension, which is a chronic disease, is to ensure management through treatment and care behavior. Aim: The aim of study was to investigate the effct and relationship between self-care behavior profies of patients with hypertension on their self-care management. Method: This descriptive study was conducted on 268 hypertension patients who applied to the cardiology outpatient clinic of a university hospital in Ankara between September 2022 and March 2023. Results: The mean overall score of Self-Care Management in Chronic Diseases was 115.220 ± 23.745, while the mean of Hypertension Self-Care Profie Behavior Scale score was 46.246 ± 9.599. When the overall scores of the patients for the Hypertension Self-Care Profie Behavior Scale and the Self-Care Management in Chronic Diseases Scale were compared, a positive high-level correlation (r = 0.702; p &amp;lt; 0.05) was discovered. There was a strong correlation between self-care behavior and management in chronic diseases, according to regression analysis (F = 258.123; p &amp;lt; 0.05). The total change in self-care behavior level was explained by self-care management in chronic diseases by 49.1% (R2 = 0.491). Self-care management in chronic diseases increased the total level of self-care behavior (ß = 0.702). Conclusion: As a result of the research, it was revealed that hypertension patients with good self-care behavior were able to control their condition better and had less diffilty in managing the disease. Therefore, strengthening patients' self-care behaviors in the management of hypertension is an important issue that nurses should focus on.

Evaluation of Candidemia in Solid-Organ Transplant Recipients.

Solid-organ transplant recipients have high rates of invasive fungal infections. Candida species are the most commonly isolated fungi. Our aim was to identify risk factors, clinical presentations, and outcomes of candidemia in solid-organ transplant recipients. We evaluated adult (≥18 years old) transplant recipients seen from May 2011 to December 2022 at Baskent University Ankara Hospital. From medical records, we retrospectively reviewed age, sex, transplant type, candidemia agent, risk factors, concomitant infections, and mortality of patients with Candida detected in blood culture. We used SPSS statistics software (version 25) to analyze data. There were 1080 organ transplants performed during the study period (717 kidney, 279 liver, 84 heart). There were 855 who were ≥18 years (655 kidney, 127 liver, 73 heart), of whom candidemia was detected in 26 (16 male; 11 kidney, 11 liver, 4 heart) with a median age of 47.5 years. The most common agents were Candida albicans and Candida glabrata. The most common chronic diseases were hypertension, cirrhosis, and cardiomyopathy. Eighteen patients had a concomitant focus of infection. Ten patients had pneumonia accompanying candidemia. The 30-day mortality rate was as high as 53.8%. The mean duration of candidemia after transplant was 23 months. Catheter-related candidemia was observed in 65% of patients. The 30-day mortality was found to be significantly higher in patients followed in the intensive care unit (P = .014), receiving total parenteral nutrition (P = .001), using broad-spectrum antibiotics (P = .001), and having pneumonia (P = .042) accompanying candidemia. For adult solid-organ transplant recipients with candidemia, careful monitoring is essential for successful management of total parenteral nutrition, central catheter, use of broadspectrum antibiotics, and invasive interventions.

Monocyte to high-density lipoprotein cholesterol ratio decreased in patients with psoriasis treated with ixekizumab.

Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a novel inflammatory biomarker which has been associated with cardiovascular diseases. To study MHR in patients with psoriasis treated with biological agents. Between April 2019 and August 2022, MHR was retrospectively evaluated in patients with psoriasis before and 3 months after treatment with infliximab, adalimumab, etanercept, ixekizumab, secukinumab, and ustekinumab in a university hospital in Ankara, Turkey. This study included 128 patients, 53 females and 75 males. 39 (30.5%) patients were treated with infliximab, 26 (20.3%) with adalimumab, 8 (6.3%) with etanercept, 18 (14.1%) with ixekizumab, 12 (9.4%) with secukinumab, and 25 (19.5%) with ustekinumab. The median MHR was 0.0127 (0.0086-0.0165) in females and 0.0146 (0.0119-0.0200) in males (p = 0.011). The median MHR decreased after treatment with adalimumab, ixekizumab, secukinumab, and ustekinumab, whereas it increased after treatment with infliximab and etanercept (p = 0.790, p = 0.015, p = 0.754, p = 0.221, p = 0.276, p = 0.889, respectively). MHR significantly decreased in patients with psoriasis after treatment with ixekizumab. Since high MHR levels have been associated with poor clinical outcomes in patients with cardiovascular diseases, ixekizumab might have a positive impact in the treatment of psoriasis patients who had cardiovascular diseases. We suggest that MHR may be useful both in establishing appropriate biological agent treatment and in the follow-up of patients with psoriasis treated with biological agents.

Adnexal torsion: a single-center retrospective study of diagnosis and treatment

Aims: This study was conducted to review the clinical, laboratory, and ultrasound findings of patients with a confirmed post-operative adnexal torsion diagnosis in a tertiary university hospital and to reflect the management of adnexal torsion.&#x0D; Methods: 44 patients (ages [15,44] with a median of 30 yr) who had an operation at Ankara University Hospital Gynecology and Obstetrics Clinics between October 2013 and February 2021 and in whom the preoperative diagnosis of adnexal torsion was confirmed intraoperatively were included in this retrospective study. Patients’ complaints, existing risk factors, physical examination, laboratory, and radiological findings were evaluated.&#x0D; Results: 26 (65%) of the patients complained about acute abdominal pain isolated on one side. Torsion was observed on the right side in 29 (66%) patients. Risk factors: History of ovarian torsion in 1 patient (2%), in vitro fertilization treatment in 5 (11%) patients, 4 (9%) of which also had ovarian hyperstimulation syndrome and 2 (5%) of them had polycystic ovary syndrome, and finally, 28 (65%) patients had increased ovarian size on ultrasound. Ovarian blood flow was not observed in 25 (81%) of 31 patients who underwent transvaginal Doppler ultrasound. Preoperative blood examination showed anemia (Hb10000/mm³) in 26 (59%), and an increase of neutrophil-lymphocyte ratio (NLR) (&gt;3) in 36 (82%). Laparoscopy was performed in 37 (84%) patients and laparotomy in 7 (16%).&#x0D; Conclusion: There is no objective diagnostic tool that can definitively lead to the diagnosis of adnexal torsion. It may be recommended to use ultrasound, Doppler, and NLR in addition to clinical findings and anamnesis. Considering the consequences of delay in the treatment, the most appropriate approach would be to perform a laparoscopy if torsion is suspected. Additionally, the patient’s age, menopausal status, ovarian pathology, and desire for fertility are factors that should be considered in the treatment decision, and ovarian protection should be the primary goal.

Identification of TLE Focus from EEG Signals by Using Deep Learning Approach.

Temporal lobe epilepsy, a neurological disease that causes seizures as a result of excessive neural activities in the brain, is the most common type of focal seizure, accounting for 30-35% of all epilepsies. Detection of epilepsy and localization of epileptic focus are essential for treatment planning and epilepsy surgery. Currently, epileptic focus is decided by expert physician by examining the EEG records and determining EEG channel where epileptic patterns begins and continues intensely during seizure. Examination of long EEG recordings is very time-consuming process, requires attention and decision can vary depending on physician. In this study, to assist physicians in detecting epileptic focus side from EEG recordings, a novel deep learning-based computer-aided diagnosis system is presented. In the proposed framework, ictal epochs are detected using long short-term memory network fed with EEG subband features obtained by discrete wavelet transform, and then, epileptic focus identification is realized by using asymmetry score. This algorithm was tested on EEG database obtained from the Ankara University hospital. Experimental results showed ictal and interictal epochs were classified with accuracy of 86.84%, sensitivity of 86.96% and specificity of 89.68% on Ankara University hospital dataset, and 96.67% success rate was obtained on Bonn EEG dataset. In addition, epileptic focus was identified with accuracy of 96.10%, sensitivity of 100% and specificity of 93.80% by using the proposed deep learning-based algorithm and university hospital dataset. These results showed that proposed method can be used properly in clinical applications, epilepsy treatment and surgical planning as a medical decision support system.

Determining the mothers’ first-aid self-efficacy in-home accidents in Turkey

&lt;b&gt;Aim:&lt;/b&gt; This study aims to determine the first-aid self-efficacy of mothers with children aged 0-4 years.&lt;br /&gt; &lt;b&gt;Methods:&lt;/b&gt; This descriptive study is conducted in a university hospital in Ankara, Turkey with 403 mothers who have children aged 0-4 years. The questionnaire method has been used to collect data in the study. The questionnaire consists of two parts. In the first part of it ‘‘the socio-demographic characteristics form’’ and in the second part of it ‘‘the first-aid self-efficacy scale’’, which is used to determine the mothers’ first-aid self-efficacy, were included. The analysis of the research data is performed with SPSS statistical program.&lt;br /&gt; &lt;b&gt;Results: &lt;/b&gt;The age range of the participants in the study is 19-46 years and the mean age is 29.41±7.40 years. 46.2% of the mothers are 19-28 years old, 93.3% are married, 39.2% are graduated from high school, and 54.8% are housewives. 86.3% of the mothers state that they have not had the first-aid training and 42.9% of them state that they have encountered a situation requiring the first-aid resulting mostly (60.1%) in an injury. The mean score of the scale is 30.90±9.50.&lt;br /&gt; &lt;b&gt;Conclusions:&lt;/b&gt; In our study, it is found that the first-aid self-efficacy of mothers is low. The mothers with an undergraduate degree have higher first-aid self-efficacy than the ones who graduated from a primary school and those who had the first-aid training have higher first-aid self-efficacy than the ones who did not receive the first-aid training. To increase the first-aid self-efficacy of mothers, the first-aid trainings should be organized by public/private health institutions and non-governmental organizations, practices should be made on models and repeated periodically. It is suggested that more centers and fathers to be included in these trainings in the future.

THE EFFECT OF TALENT MANAGEMENT ON NURSES' PERCEPTIONS OF WORK MOTIVATION AND ORGANIZATIONAL TRUST

This study was conducted to determine the Effect of Talent Management on Nurses' Perceptions of Work Motivation and Organizational Trust. In this context, data obtained from all nurses working in ministry of health hospitals and university hospitals in Ankara were evaluated. For the data, the talent management practices scale consisting of 7 sub-dimensions (attraction, selection and placement, commitment, retention, training, rewarding, talent pool), nurse work motivation scale consisting of 25 factors and the organizational trust scale, which consists of 3 sub-dimensions (trust in the institution, trust in colleagues, trust in the manager) was used. As a result of the research, nurses' perceptions of talent management were found to be moderate (x=3,146), their perceptions of work motivation (x=3,839) and organizational trust perceptions (x=3,566) were found to be higher than the average. According to the findings, nurses' perceptions of talent management, work motivation and organizational trust have positive correlation to each other. The perception of talent management of nurses working in the ministry of health was found to be higher than those in the university. It has been concluded that the nurses working at the university trust their institution more than the ministry of health. The effect of talent management on work motivation was found to be higher in university hospitals. On the other hand, it has been concluded that the effect of talent management on organizational trust is higher in ministry of health hospitals.

Examination of Nurses’ Attitudes About Patient Safety According to Sociodemographic Characteristics

Background: Patient safety is a high priority for healthcare systems worldwide. It is considered an indicator of the quality of care. Establishing a patient safety attitude is the first priority in order to create a patient safety culture. Nurses play a critical role in protecting and supporting patients because of the nature of their job. In this way, especially nurses’ attitudes about patient safety will be determined, and threats to patient safety that may arise in the future will be prevented. Methods: In this regard, this study aimed to examine the nurses’ attitudes about patient safety according to certain sociodemographic characteristics. To accomplish this goal, the relevant data of the nurses were obtained by using the Patient Safety Attitude Scale consisting of 6 dimensions and 46 items. The research population consists of 245 nurses working in a University hospital in Ankara. The sample was not calculated, and a questionnaire was distributed to all employees of which 215 nurses completed the questionnaire. Data were collected between 1-30 April 2021. Ethics committee approval was obtained from the hospital. The data obtained were subjected to multivariate regression analysis. Results: The scale used was reliable (r=0.80). The mean of the general patient safety attitude scale is 3.22 with a standard deviation of 0.54. The majority of the participants were found to be between the age groups of 19-26 (38.1%), women (84.7%), and single (52.1%). We also found that the weekly working time of nurses and whether they got patient safety training or no had a statistically significant effect on patient safety attitudes (p&lt;0.05). Therefore, it could be said that as the working time of nurses increased, a decrease in patient safety attitudes were observed, and they exhibited more patient safety attitudes as they got patient safety training. Conclusion: From this point of view, determining the weekly working hours of nurses more appropriately and making them more trained about patient safety may play a key role in creating a higher level of patient safety attitude.

Statin adherence in patients with high cardiovascular risk: a cross-sectional study

ABSTRACT Objectives Statin adherence is an essential problem although lifetime medication is recommended especially in patients with high cardiovascular risk. The importance of perceived risk as a predictor of adherence among cardiology patients has not been fully explored. This study aimed to test the importance of perceived risk as a predictor of statin adherence amongst hypercholesterolemic patients to identify predictors associated with poor adherence. Methods This cross-sectional study was conducted at cardiology outpatient clinics of the University hospital in Ankara, Turkey. A total of 327 consecutive patients with high CV risk were recruited. Self-reported Morisky Green Levine Medication Adherence Scale was used to assess statin adherence. Results Of the patients studied, 34.5% had concerns about side effects. Also, the mean age was 63.85 ± 11.29 years, 66.1% were men, 32.4% applied non-drug alternative therapies, 53.2% had a Mediterranean-style diet and 20.8% checked their lipid values irregularly. Participants reported 50.2% high, 30% moderate, and 19.9% low statin medication adherence. Low-density lipoprotein cholesterol (LDL-C), Total Cholesterol (TC), Triglyceride (TG) and high-density lipoprotein (HDL) control rates were 44.6%, 74.3%, 61.5% and 41.6%. On multiple logistic regression, concern about side effects was associated with a statistically significant quadruple elevation of odds of non-adherence. Also, being male, former smokers, not having complementary interventions, having regular visits, being educated for more than 5 years, having low depressive symptom scores, living in a rural, being never or former smokers, employee were significant predictors of high medication adherence scores. Conclusion Approximately half of the patients reported high medication adherence. Proper strategies to improve adherence would include patient education efforts focused on patients with concerns about side effects and those who are female, less educated, current smokers, interested in complementary interventions, have irregular follow-up visits, and have depressive symptoms. Brief medication adherence scales may facilitate the assessment of patients’ adherence.

Ruhsal Bozuklukları Olan Bireylere Bakım Verenlerde Bilişsel Esneklik, Empatik Eğilim ve Hastalık Yükü

Araştırmanın örneklemini Ocak 2021-Ocak 2022 tarihleri arasında Ankara’da bir üniversite hastanesinin psikiyatri servisinde yatarak tedavi alan ve araştırmaya dahil olma kriterlerini karşılayan 45 bakım veren birey oluşturmuştur. Araştırmanın verileri; ‘Katılımcı Bilgi Formu’, ‘Bilişsel Esneklik Ölçeği’, ‘Empatik Eğilim Ölçeği’ ve ‘Hastalık Yükü Ölçeği’ veri toplama araçları kullanılarak araştırmacılar tarafından yüz yüze toplanmıştır. Araştırma sonucunda elde edilen verilerin analizi için Sosyal Bilimler İçin İstatistik Paket Programı (SPSS Inc. Chicago,IL,USA) 22.0 kullanılmıştır. Tanımlayıcı veriler ortalama, standart sapma, sayı ve yüzde ile belirtilmiştir. Verilerin normal dağılıma uyum sağlayıp sağlamadıkları test edilmiş ve normal dağılıma uyum göstermemesi nedeniyle gruplar arası karşılaştırmalarda Mann-Whitney U Testi ve Kruskal Wallis Testi kullanılmıştır. Veriler arasındaki ilişkilerin incelenmesi ise Spearman’s Correlation Testi ile yapılmıştır. İstatistiksel anlamlılık p≤0.05 olarak alınmıştır. Sonuç olarak; ruhsal bozukluğu olan bireylere bakım verenlerin bilişsel esneklikleri, empatik eğilimleri ve hastalık yükleri arasında istatistiksel olarak anlamlı ilişki olduğu saptanmıştır.

QUALITY OF LIFE OF CHILDREN WITH CANCER ACCORDING TO MOTHERS: A QUALITATIVE STUDY

Hastanede yatan iki-yedi yaş arasındaki kanserli çocukların yaşam kalitelerinin anne görüşlerine göre incelenmesini amaçlayan araştırma, nitel boyutta olgubilim (fenomenoloji) desendedir. Araştırmanın çalışma grubu, Ankara’da bulunan iki üniversite hastanesinin onkoloji servisinde yatan, kanser tanısını en az altı ay önce almış, majör fizik ve motor gelişim bozukluğu olmayan 10 çocuğun annesinden oluşmaktadır. Araştırmanın verileri “Genel Bilgi Formu” ve “Anne Görüşme Formu” ile toplanmıştır. Verilerin analizinde içerik analizi ve betimsel analiz yönteminden yararlanılmıştır. Annelerin çoğunluğu kanser hastası olan çocuklarının; fiziksel sorunlar yaşadığını, tanı ve tedavi sürecinde olumsuz duygu değişimleri yaşadığını belirtmiştir. Anneler, çocuklarının sosyal, duygusal, dil ve kaba motor gelişimlerinin olumsuz etkilendiğini, fiziksel sorunlarının olduğunu, iletişim sorunları yaşadıklarını, oyun yaşantılarının değiştiğini ve yaşam kalitelerinin hastalıktan etkilendiğini belirtmişlerdir. Ayrıca, çocuklarının tanı ve tedavi sürecinde çocuk gelişimci ile karşılaştıklarını, hizmet aldıklarını ve aldıkları çocuk gelişimi hizmetlerinden memnun olduklarını ifade etmişlerdir. Ortaya çıkan temalar doğrultusunda, kanserli çocukların yaşamış olduğu fiziksel sorunlar, duygu değişimleri, gelişimleri, fiziksel sorunları, iletişim sorunları, oyun yaşantıları, yaşam kaliteleri ve çocuk gelişimcilerle karşılaşma durumları ile ilgili sonuçlara ulaşılmıştır.

CN15 Individual factors leading to delay in diagnosis in patients with colorectal cancer and their illness perceptions

The purpose of this study was to determine the time elapsed between the first symptoms and seeking medical help, factors contributing to the delay and disease perception in patients with colorectal cancer. The study was conducted at the medical oncology outpatient clinic of a University Hospital in Ankara and included 114 patients who were diagnosed with colorectal cancer. The data were obtained by using the questionnaire form and the brief illness perception questionnaire. The elapsed time between patients’ first symptoms and seeking medical health was classified into ‘‘normal’’ when it was less than one month, ‘‘delay’’ when it was between one and three months, ‘‘long-term delay’’ when it was more than three months, and ‘‘very serious delay’’ when it was more than six months. In the analysis of the data, chi-square test, one-way analysis of variance and correlation tests were used. The mean elapsed time between patients’ first symptoms and seeking medical health was 7.27±11.02 month (range: 1 - 62.5 month), 60.6% of patients were delayed over a month and there is a serious delay in 31.6% of them. Most of the patients (76.3%) stated that they did not know the signs and symptoms of colorectal cancer and 16.7% stated that they had a screening test. It was determined that 89.9% of patients experienced symptoms and signs before colorectal cancer diagnosis. The most common complaints were changes in bowel habits (20.3%), rectal bleeding (14.1%) and abdominal pain (10.3%). When the factors contributing to the delay were evaluated, 60% of them did not stated any reason, 17% stated perceiving the symptoms as temporary or insignificant. A significant relationship was found between the delay in diagnosis and level of education and the change in bowel habit (p<0.05). The mean score of brief illness perception was found to be 21.74 ± 11.36 (range: 0- 56). The three most important factors that they believed to cause illness were stress (32.8%), nutrition (24.9%) and sadness (13.6%). Although the individuals participating in the study have symptoms that may be a symptom of colorectal cancer; there was considerable delay in the time to seeking medical help due to lack of awareness about the symptoms of colorectal cancer.

Throat Symptoms Before and After Septal Surgery in Adults With Nasal Septum Deviation.

To investigate subjective throat symptoms with the Qualities of Sore Throat Index (QuaSTI) in adults with nasal septum deviation. Prospective study. Baskent University Ankara Hospital. Group 1 included patients with septum deviation. Preoperative data were obtained through evaluation of subjective nasal obstruction with the NOSE (Nasal Obstruction Symptom Evaluation) and throat symptoms with the QuaSTI (group 1a). After 3 months, the same patient group was reevaluated with the NOSE and QuaSTI to obtain postoperative data (group 1b). Group 2 was formed of healthy volunteers with no nasal obstruction. The mean ± SD and median (range) values of the QuaSTI total score were 33.39 ± 29.50 and 18.5 (0-90) in group 1a, 7.49 ± 4.31 and 7 (0-18) in group 2, and 7.58 ± 9.24 and 4.50 (0-49) in group 1b (group 1a vs 2, P < .001; group 1a vs 1b, P < .0001). A significant difference was determined between groups 1a and 2 with respect to the QuaSTI sensory score (26.58 ± 23.54 and 18 [0-73] vs 6.51 ± 3.58 and 7 [0-15], P < .001, respectively) and between groups 1a and 1b for the QuaSTI functional score (6.03 ± 6.62 and 3 [0-20] vs 1.50 ± 2.47 and 0.50 [0-13], P = .004). No significant difference was found between groups 1a and 2 in terms of the QuaSTI emotional score (P = .126). Various persistent sensory and functional throat symptoms can be seen in patients experiencing nasal obstruction associated with septum deviation, and the majority of these symptoms recover after septal surgery.

The prevalence and distribution of human papillomavirus in 4267 Turkish women with or without cervical lesions: A hospital-based study.

In the present study, it was aimed to screen the genotypes of human papillomavirus(HPV) retrospectively in women with gynecological symptoms who were admitted to a tertiary care university hospital in Ankara, Turkey. A total of 4267 cervical swab samples of women aged 18-79 years were sent to Medical Virology Laboratory from January 2017 to November 2020. Nucleic acid extraction and amplification of samples were done by an automated system. The test can detect 14 high-risk HPV (HR-HPV) types in a single analysis that performs a real-time polymerase chain reaction, by providing individual results on the highest-risk genotypes HPV 16 and HPV 18 and pooled results on other high-risk genotypes (OHR-HPV) (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68). HPV DNA positivity was detected in 14.2% (605/4267) of the samples. HPV type 16 and type 18 were detected in 2.4% and 0.7% of the samples, respectively. OHR-HPV types were found in 8.8% of the samples. Of the 1.9% and 0.4% samples had mixed types with type 16+OHR-HPV and type 18+OHR-HPV, respectively. The results of this study presented the rates of HR-HPV genotypes of a university hospital in Ankara, over a 4-year period. It was observed that the positivity rate of type 18 is decreasing and someOHR-HPV types are increasing. HPV vaccination is not in the national immunization program in Turkey yet, however,HPV vaccines are available and the vaccination rates for women are increasing.

Vein-associated tumors: Our six-year surgical experiences in Başkent University Ankara Hospital

Vein-associated tumors: Our six-year surgical experiences in Başkent University Ankara Hospital

Retrospective evaluation of viral respiratory tract infections in a university hospital in Ankara, Turkey (2016-2019).

Viruses are responsible for two-thirds of all acute respiratory tract infections. This study aims to retrospectively detect respiratory tract viruses in patients from all age groups who visited the hospital. A total of 1592 samples from 1416 patients with respiratory tract symptoms were sent from several clinics to the Molecular Microbiology Laboratory at Gazi University Hospital from February 2016 to January 2019. Nucleic acid extraction from nasopharyngeal swabs, throat swabs or bronchoalveolar lavage (BAL) samples sent to our laboratory was done using a commercial automated system. Extracted nucleic acids were amplified by a commercial multiplex-real time Polymerase Chain Reaction (PCR) method, which can detect 18 viral respiratory pathogens. Among 1592 samples, 914 (57.4%) were positive for respiratory viruses. The most prevalent were rhinovirus (25.2%) and influenza A virus (12.1%), the least prevalent was the bocavirus (2.6%). Rhinovirus was the most detected as a single agent (21.2%, 194/914) among all positive cases, followed by coronavirus (9.3%, 85/914). The detection rates of coronavirus, human adenovirus, respiratory syncytial virus A/B, human parainfluenza viruses, human metapneumovirus-A/B, human parechovirus, enterovirus and influenza B virus were 9.9%, 8%, 7.7%, 5%, 3.4%, 3.1%, 3%, and 2.8%, respectively. The most detected viral agents in our study were influenza A virus and rhinovirus. Laboratory diagnosis of respiratory viruses is helpful to prevent unnecessary antibiotic use and is essential in routine diagnostics for antiviral treatment. Multiplex Real-time PCR method is fast and useful for the diagnosis of viral respiratory infections.

Effectiveness of a Pressure Injury Prevention Care Bundle; Prospective Interventional Study in Intensive Care Units.

The purpose of this study was to assess the effectiveness of a pressure injury prevention care bundle. Prospective interventional study. Participants were 13 nurses and 104 patients cared for in the intensive care unit for at least 24 hours in a university hospital in Ankara, Turkey. The study was conducted in 2 stages: the pre-care and post-care bundle stages. In the pre-care bundle stage, the pressure injury incidence of the patients was followed by the nurses. At the end of the third month, the researcher held a 1-day training program for the nurses about the care bundle use to promote correct implementation. In the post-care bundle stage, the nurses provided care according to the bundle. Compliance with the care bundle was assessed. Pressure injury incidence rates in the pre- and post-care bundle stages were compared. The incidence of stage 1 pressure injury was 15.11 (1000 patient-days) in the pre-care bundle stage and 6.79 (1000 patient-days) in the post-care bundle stage; this reduction was not statistically significant. A pressure injury prevention bundle was implemented in an intensive care unit, resulting in a decline in stage 1 pressure injuries.