Background: Mental health is vital to university students' overall well-being and academic performance. In Nigeria, cultural and institutional barriers often limit mental health awareness and support. This study explores the awareness and practices of mental health promotion among students at the University of Calabar, Nigeria, to address gaps and improve intervention strategies. Materials and Methodology: A mixed-methods approach was adopted, utilizing quantitative surveys (n=500) and qualitative interviews (n=25) with students and university staff. Data collection focused on mental health awareness, help-seeking behaviors, and the accessibility of mental health services. Quantitative data were analyzed using descriptive and inferential statistics, while thematic analysis was applied to qualitative responses. Results: Findings revealed that while 60% of students were aware of basic mental health issues, only 30% actively engaged in mental health-promoting practices. Significant barriers were identified, including stigma, lack of information, and cultural beliefs. Additionally, 45% of students associated mental health challenges with spiritual causes. Female students demonstrated more positive attitudes towards seeking help than males. Only 12% of students had accessed professional mental health support, with most relying on informal sources such as friends or religious leaders. Conclusion: The study highlights significant gaps between mental health awareness and practice among University of Calabar students. Addressing stigma, increasing the visibility of mental health services, and integrating mental health education into university curricula are critical steps. Evidence-based recommendations for promoting mental health include peer-led initiatives, enhanced accessibility to services, and culturally sensitive interventions.
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