Universitas Indonesia Research Articles

Investigating Brand Awareness, Brand Image, and Perceived Quality on Customer Loyalty

This study investigates the impact of brand awareness, brand image, and perceived quality on customer loyalty, with a focus on Telkomsel users within the Creative Business program at Universitas Indonesia. Employing a quantitative research methodology, data were collected from 50 respondents using a structured questionnaire and analyzed using SPSS 26. The findings reveal that all three factors—brand awareness, brand image, and perceived quality—positively influence customer satisfaction, which in turn significantly enhances customer loyalty. Specifically, perceived quality emerged as the most influential factor driving customer satisfaction, followed by brand image and brand awareness. The study underscores the critical role of perceived quality in fostering customer loyalty, suggesting that Telkomsel’s success in retaining customers is largely attributed to its high service standards. This research contributes to the literature on brand management in the telecommunications sector and offers practical insights for enhancing customer loyalty through strategic improvements in brand perception and service quality.

Comparison of discussion-based and simulation-based learning methods using the Gas Man® on knowledge of the uptake and distribution of inhalation anesthetics of anesthesia resident: A randomized controlled trial

Abstract Background and Aims: Inhalation anesthetics is basic knowledge that must be mastered by an anesthesiologist. Lack of competencies can result in higher morbidity and mortality in anesthesiology practice. Various learning methods were developed to improve understanding and retention. With the advancement of technology, the utilization of screen-based simulation (SBS) using applications is common, such as the Gas Man® application, to help students understand physiology, pathophysiology, and kinetic inhalation anesthetic agents. The primary objective of this study was to compare the knowledge improvement of anesthesia residents between the simulation-based and discussion-based learning methods on the uptake and distribution of anesthetic inhalation. The secondary objective was to compare the satisfaction levels of participants in both learning methods. Material and Methods: This study is a randomized controlled trial involving anesthesiology and intensive care residents from the Faculty of Medicine, Universitas Indonesia (FKUI) 2022–2023. The participants were randomized into two groups (simulation and discussion groups). A senior attending anesthesiologist led the discussion. The participants answered a pretest, followed by a 1-hour lecture about inhalation gas. Lastly, participants answered a posttest and filled in the satisfaction survey. Statistical analyses used the Mann–Whitney test to compare the two groups. The Wilcoxon test was used to compare the knowledge improvement between the two groups. Results: Thirty-eight residents underwent simulation-based (n = 19) and discussion-based (n = 19) learning methods. The simulation group demonstrated a median (interquartile range) posttest score of 80 (76.67–83.33) compared with the discussion group with a score of 50 (40–66.67) (P value <0.05). More than half of the participants in both groups answered “satisfied.” Conclusion: The simulation-based learning method using the Gas Man® application performed better than the discussion-based learning method on increasing knowledge of the uptake and distribution of inhalation anesthetics in anesthesia residents. Key Message: Simulation-based learning method may improve understanding and retention. This study supported the conclusion that the simulation-based learning method with Gas Man is better than the discussion-based learning method for improving knowledge of the uptake and distribution of inhalation anesthetics.

Expectation and Needs of Medical Students Towards the Implementation of Virtual Simulation in Learning Rational Use of Medicine.

The irrational use of medicines remains prevalent globally despite education efforts, leading to decreased treatment quality and increased healthcare costs. With the rise of online learning during the COVID-19 pandemic, virtual simulation offers a promising solution to enhance the teaching of rational medicine use among medical students. This study aimed to investigate medical students' perspectives and needs regarding the implementation of virtual simulation in learning the rational use of medicines. This study, conducted at Universitas Indonesia from August 2022 to September 2023, used a mixed-method approach to assess the needs for developing virtual simulation in education of rational medicine use. A validated questionnaire with 14 closed-ended and 14 open-ended questions was completed by 281 medical students. The quantitative data were analysed descriptively, using SPSS v16, while thematic analysis was applied to open-ended responses. Students perceived virtual simulations to be the most effective tool for distance learning and suggested features like case scenarios, realistic representation, a good user interface, and user-friendly navigation. The majority preferred a 10-20-minute duration for virtual simulations. Additionally, 52.3% had no prior knowledge of the rational use of medicines, but acknowledged its importance. Virtual simulations could be used to explain the concept, management, and implementation of the rational use of medicines. Virtual simulation should be implemented in distance learning on rational medicine use to increase students' motivation, understanding, retention, interactivity, and focus. The findings might be utilized by medical educators to tailor virtual simulation design to meet medical students' needs and expectations.

International comparison of vocational pre-service teachers’ character education in Indonesia and Malaysia

This study examines the commitment of vocational teacher education students at Universitas Negeri Yogyakarta, Indonesia, and Universiti Tun Hussein Onn Malaysia (UTHM) in applying core character values. The global trend in teacher education links education and economic growth, emphasizing students' competence for the job market. However, teachers are also expected to address social and moral cohesion in the younger generation. The research involved 177 third- and fourth-year students at FPTV UTHM Malaysia and an equal number at FT-UNY, utilizing a questionnaire based on core character values. The findings indicate moderate commitment levels (58.75%) among university students. UTHM students scored slightly higher (2.42) than UNY students (2.28). The study shows that character education for vocational teacher education students in both Indonesia and Malaysia has not reached optimal levels, emphasizing the need to investigate more effective character education models for future vocational teachers.

Promising effect of cisplatin and melatonin combination on the inhibition of cisplatin resistance in ovarian cancer

Background Ovarian cancer management has not yet given a satisfactory result, and the recurrence rate is still high. One of the reasons for this is resistance to chemotherapy. Melatonin and cisplatin may be involved in the chemotherapy resistance of ovarian cancer. Methods A laboratory experiment was performed using melatonin and cisplatin in the SKOV3 cell, from September 2020 to November 2021 at the SCTE and Integrated Laboratory & Research Center Universitas Indonesia. Several variables were used, such as doxorubicin, melatonin, cisplatin, and combination of cisplatin and melatonin at several concentrations (1×, 3/4×, 1/2×, and 1/4×). A total of 24 samples were included and divided into 8 groups. The IC50 values of melatonin, doxorubicin, and cisplatin as well as cell viability was calculated via MTS assay. Subsequently, flow cytometry was performed to assess the effect of cisplatin and melatonin on the mechanisms of CTR1, p-glycoprotein, GSH, ERCC1, e-cadherin, and apoptosis. Analysis of variance and Bonferroni test were employed for the study. Results The IC50 values of melatonin, cisplatin, and doxorubicin were 1.841 mM, 117.5 mM, and 14.72 mM, respectively. The combination groups of cisplatin and melatonin reduced cell viability; decreased the CTR1 mean (19.73), Pgp (6.7), GSH (11.73), and ERCC1 (4.27) in the combination 1 (C1) group; and increased e-cadherin (32.2) and annexin V (53.57) also in the combination 1 (C1) group. Conclusions The combination of melatonin and cisplatin might have an impact on drug resistance via several mechanisms in ovarian cancer.

Preface

3nd ASEAN International Conference on Energy and Environment (AICEE) Nusa Dua Bali, Indonesia, 24 August 2023 Accelerating a Just, Secure, and Resilient Energy Transition in ASEAN through Innovation and Interconnectivity Introduction ASEAN Centre for Energy (ACE) is an intergovernmental organization within ASEAN structure that represents the 10 ASEAN Member States’ (AMS) interests in the energy sector. With their growing population and economic growth, AMS are expected to be a new global epicentrum of energy market in the future. This trend pushes energy security as one of the highest priorities in energy development in the region. On the other hand, the ASEAN Plan of Action for Energy Cooperation (APAEC) Phase II: 2021-2025, a regional blueprint on energy cooperation, has a theme and sub-theme in which embracing energy transition is one of the key elements to achieve regional energy security and environmental sustainability. To further accelerate the progress towards a sustainable future, enhance collaboration among various sectors, and bridge the gap between academia, policymakers, and businesses, we are delighted to announce that the ASEAN Centre for Energy (ACE) will be hosting the 3rd ASEAN International Conference on Energy and Environment (AICEE) in conjunction with The ASEAN Energy Business Forum (AEBF) 2023 and The 41st ASEAN Ministers on Energy Meeting (AMEM) on August 24-25, 2023. These events will offer a platform for academics, practitioners, and stakeholders to network, exchange ideas, and explore innovative solutions to address the challenges of energy and the environment. The conference will take place in Bali, a stunning island renowned for its breathtaking scenery and rich cultural heritage. This unique location will provide participants with a memorable and immersive experience, allowing them to explore the fascinating local culture and gain a deeper understanding of the region’s energy and environmental issues. The event promises to be a remarkable occasion fostering collaboration and driving progress towards a sustainable future. This year’s AICEE is the third edition of the annual flagship conference held by ACE. Under the 3rd AICEE, we received 145 extended abstracts, accepted 96 extended abstracts to be compiled as Conference Proceeding and invited 76 authors to submit their full papers. To proceed with the publication, 59 papers are recommended to be the IOP Publishing process, and 44 papers are accepted for the IOP Publication of 2023 AICEE Volume. The 3rd AICEE was convened in-person presentation in partnership with Universitas Pendidikan Nasional (UNDIKNAS), Universiti Teknologi Malaysia (UTM), Energy Research Institute (ERI) Chulalongkorn University, National Energy Technology Center-National Science and Technology Development Agency (ENTEC-NSTDA), (ASEAN Climate Change and Energy Project (ACCEPT), Universitas Indonesia (UI), Institut Teknologi Bandung (ITB), Hawaii University, Universiti Tenaga Nasional (UNITEN). List of Theme, Topic, Key Dates, Participants, Agenda, Steering Committee, Scientific Committee, Organizing Committee and Documentation are available in this Pdf.

Perceived Enablers of and Barriers to Serious Game as Oral Histology Learning Strategy for Undergraduate Dental Students.

Previously, we reported the serious game HistoRM as an innovative learning approach for an oral histology course. This study aimed to examine the impact of HistoRM on summative assessment and the enablers and barriers factors affecting HistoRM as an interactive learning strategy in an oral histology course. A crossover randomized controlled trial was performed. Study participants were first-year dental students at the Universitas Indonesia. The average final grades of students who participated in HistoRM serious game were significantly higher than those of students who did not participate in this trial (p < 0.001). Positive responses of HistoRM were observed in the learning content, games and learning experience domains. The enabler factors most recognized by the students were the game method, which helped students to understand the learning materials; the immediate feedback provided following each gameplay; as well as the fun and interesting gameplay. The barrier factors most recognized by the students were some challenges of the gameplay, which resulted in a longer time needed to study. While the HistoRM serious game can stimulate student motivation and engagement in learning oral histology, overcoming the barriers is essential for the implementation of serious games as a complementary learning approach in the dental curriculum.

The influence of Intellectual capital (IC) disclosure and geographic location on the sustainability of higher education: A case in Southeast Asian universities

Purpose: This research aims to examine the influence of intellectual capital disclosure and the geographical location of universities on the sustainability of higher education institutions in Southeast Asia. Design/methodology/approach: This research is quantitative and uses secondary data obtained through the annual reports of universities that have the Universitas Indonesia Green Metric Rank. This research uses two stages of data analysis techniques, namely the content analysis stage to determine the number of Intellectual Capital disclosures and the hypothesis testing stage. The analysis tool uses the SPSS version 23 application. The population of this research includes all universities in Southeast Asia that are included in the UI Greenmetric World University Rankings. The sampling technique used was purposive sampling technique, which resulted in 86 analysis units of higher education institutions in Southeast Asia. Findings: The research results prove that the geographical location of universities has a negative and significant influence on Universitas Indonesia Green Metric’s performance in Southeast Asia and human capital has a positive influence on UIGM’s performance in Southeast Asia. However, the structural capital and relational capital components do not affect the UIGM performance of universities in Southeast Asia. Originality/value: The originality of the research is the use of higher education sustainability variables with UIGM proxies and modified IC indicators for universities and geographical areas that have not been widely used to see whether there are fundamental differences in the disclosure of intellectual capital for higher education institutions in Southeast Asia.

Nutritional Status, Sugar Sweetened Beverage Consumption and Physical Activity Level in Male and Female College Students Living in Dormitory

Introduction: The global prevalence of obesity is on the rise, including in Indonesia. High energy intake from sugar is a growing concern worldwide due to its association with weight gain, tooth decay, and non-communicable diseases. A prior study revealed that 10.9% of Indonesian adults consumed energy from sweetened beverages in excess of the WHO recommendation. This study aimed to assess the consumption of sweetened beverages in male and female college students in Indonesia. Method: The study was conducted at Universitas Indonesia and involved 107 subjects aged 19-21 years who resided in student dormitories. Result: The result found the median BMI in female was higher than male. In female, 3 out of 10 students was overweight-obese, while 1 out of 10 in male. Interestingly, the median daily intake of sweetened beverages significantly higher in male than female; 387 (25–1580) vs 246 (0–762) ml/day (p=0.001). Added sugar content in beverages in males was higher than half of Indonesian recommendation (28.4 [1.9–134.4] vs 19.2 [0–61.1]) which contributed to energy as much as 170.9 (12.4–625.7) kcal/ day or about 8.9% of total energy intake than female (108.5 [0–394.4] kcal/day). Compared to Indonesian guideline, 12% of male subjects consumed added sugar higher than 50 g/day. Simultaneously, 7 out of 10 subjects consumed energy from sweetened beverages higher than 10% of their total energy intake (WHO recommendation). The BMI and prevalence of overweight-obese were higher in female, while the sweetened beverage was higher in male. It might be caused by the physical activity in male was higher than female. Although male had higher energy intake from SSB, their energy output through physical activity balanced with energy input. Conclusion: These finding alerted the university as educational institution should take an action to prevent this issue since the prevalence of overweight-obesity and sweetened beverage consumption has occurred in young age.

Medication Adherence among Drug-Resistant Tuberculosis (DR-TB) Patients at Universitas Indonesia Hospital

Background: Drug-resistant tuberculosis (TB-DR) is a deadly disease caused by infectious agents. Indonesia is one of the countries with the highest drug-resistant tuberculosis (TB-DR) rates in the world. The prevalence of tuberculosis cases in Depok City between 2019-2022 showed an increase in cases every year. This study aims to measure the level of adherence of drug-resistant tuberculosis (TB-DR) patients to their treatment using the Eight-Item Morisky Medication Adherence Scale (MMAS-8) questionnaire.Methods: This study is an observational study using a cross-sectional study design, conducted from February 2024 to March 2024 at the University of Indonesia Hospital. Eighty-seven respondents participated in this study. Respondents completed the validated Indonesian version of the MMAS-8 questionnaire after signing informed consent forms.Results: The results of the study showed that 50.6% of respondents had low adherence levels, 47.1% had moderate adherence levels, and 2.3% had high adherence levels. The data was then statistically analyzed using the SPSS version 29 statistical package with Chi-Square analysis, which resulted in a significant correlation (P&lt;0.05) between adherence levels and gender.Conclusion: There was a significant correlation between gender and respondent adherence. More than 50% of drug-resistant tuberculosis (TB-DR) patients at the University of Indonesia Hospital still have low adherence levels to their treatment.

Sustainability and Finance in Developing Nations: Current State and Future Directions

Using the bibliometric analysis on a corpus of 492 Scopus-indexed documents, this study comprehensively analyses the literature on sustainable finance, revealing significant growth from one article in 1991 to 53 in 2024, with 2023 being the peak publication year. The highest citations occurred in 2020, totaling 1,531. Saini, N. and Singhania, M. are among the most productive authors, while Rehman, M.A. leads in citations. Garcia A.S. ranks first among the most cited authors. The Journal of Cleaner Production is the most productive and cited journal. Universitas Indonesia and Kwame Nkrumah University Malaysia are the top productive institutions. Keyword analysis highlights "Sustainable Development" as a central theme, with emerging markets prominently featured. Gracia A.S. leads collaborative research activities, indicating strong interdisciplinary cooperation in sustainable finance.

Determination of warfarin in volumetric absorptive microsampling by liquid chromatography-tandem mass spectrometry

ObjectiveThis study aims to develop and validate bioanalytical method for quantifying warfarin in VAMS samples using liquid chromatography tandem mass spectrometry (LC-MS/MS), directly implementing the method to patients receiving warfarin therapy. MethodsThe UPLC-MS/MS method was developed and optimized, with quercetin as the internal standard. Sample preparation was carried out using protein precipitation with methanol-acetonitrile (1:3 v/v). ResultsChromatographic separation was achieved using Acquity® UPLC BEH C18 column with 0.1 % formic acid-acetonitrile-methanol (30:69:1 v/v) as mobile phase, in isocratic elution. Multiple Reaction Monitoring (MRM) detection was done using m/z values of 307.10 → 161.06 for warfarin and 301.03 → 150.98 for quercetin as internal standard, using Electrospray Ionization (ESI) negative ion source. The clinical application of the bioanalytical method was carried out on 25 patients receiving warfarin therapy at Universitas Indonesia Hospital and warfarin levels were well within the calibration range from 6.05 to 431.39 ng/mL. ConclusionA novel method has been developed to analyze warfarin in VAMS samples. This method has been fully validated according to guideline from FDA 2022 and is linear in the range of 5–500 ng/mL and the value of r ≥ 0.9977, and successfully applied for the analysis of warfarin in VAMS samples of clinical patients.

Class Bias in Indonesian’s Post-Reformation Film Revival

This paper describes how the Indonesian film industry has experienced a revival to counter Hollywood dominance since the beginning of the Reformation Era in the 2000s. However, conditions that hinder the growth of the Indonesian film industry are mainly due to the concentration of movie theatres and film screens in big cities. Indonesian films are predominantly consumed by groups from the upper socioeconomic levels and ignored by the middle and lower economic strata. This article seeks to portray whether the movement against Hollywood dominance would be effective if Indonesian films were only directed at this particular audience segment. To analyse the development of the Indonesian film industry in the post-reformation era (2000-current), the authors used a nationwide survey from Saiful Mujani Research and Consulting, conducted from August 31 to September 9, 2019, shortly before the COVID-19 Pandemic hit globally. To corroborate the survey's findings, the authors also distributed a closed questionnaire to 100 students at Undergraduate Program in Communication, Universitas Indonesia, and followed this with in-depth interviews with several students. The authors seek to study the revival of Indonesian films despite the decade-long dominance of Hollywood films and, recently, South Korean films. The research question proposed in this paper is: Can Indonesia break away from Hollywood's dominance? For this reason, this research focuses on the availability and modality of Indonesian market-targeted millennial and post-millennial film audiences to support the revival of the national film industry to compete with the dominance of Hollywood films. Keywords: Class bias, Indonesian films’ revival, taste culture, movie theaters, Hollywood films.

Epistemology Of Legal Studies: Research Method Characteristics of Theoretical Law Bearers in Indonesia

Doctorate students of legal studies programs in Indonesia use various research methods. This paper aims to analyze research methods patterns used by doctorate students of legal studies in six Indonesian universities. The authors analyzed dissertations from the Doctorate Program of Legal Studies in the following universities: Universitas Indonesia (Depok, West Java), Universitas Padjajaran (Bandung, West Java Province), Universitas Sumatera Utara (Medan, North Sumatra Province), Universitas Airlangga (Surabaya, East Java Province), Universitas Diponegoro (Semarang, Central Java Province), and Universitas Hasanuddin (Makassar, South Sulawesi Province). This philosophical method research used secondary data obtained using the literature review method in the form of dissertations from six universities that establish legal studies doctorate programs. Results showed that there are three patterns of epistemology used by doctorate program students of legal studies in Indonesia, namely those that are based on the doctrinal approach, those based on the non-doctrinal approach, and those based on the combined approach between the doctrinal and the non-doctrinal approaches. In this research, some dissertations with the epistemological pattern were also found that are is based on theoretical assumptions sourced from the teachings of the positivistic legal philosophy school of thought as taught by Austin and Kelsen.

Perbandingan Hasil Radiografi Efusi Pleura Pada Proyeksi Right Lateral Decubitus (RLD) Dan Left Lateral Decubitus (LLD) Pada Klinis Dengue Haemoragic Fever (DHF) Di RSU. Wisata Universitas Indonesia Timur

Dengue Hemorrhagic Fever (DHF) is an infectious disease that can be fatal in a relatively short time. This disease is classified as "difficult to differentiate" from other dengue fever diseases. If without quick and appropriate treatment, the sufferer could fall into an even more fatal condition. And generally the supporting action taken is an X-ray examination of the chest to assess the presence of fluid in the pleura as a result of the Aedes Aegypti mosquito virus. The purpose of this research is to know the Comparison of Radiographic Results of Pleura Effusion on Right Lateral Decubitus Projection and LLD ( Left Lateral Decubitus ) in DHF ( Dengue Haemoragic Fever ) case. This research was conducted in RSU.Wisata Radiology installation of Universitas Indonesia Timur with quantitative research method with experimental design approach. Data collection is done by finding literature, observation, interview, and documentation. From the results of the research that the image of pleural effusion with RLD projection ( Right Lateral Decubitus ) shows better radiographic picture in assessing the level of pleural effusion with clinical DHF ( Dengue Haemoragic Fever ).

Environmental Factors and Management Strategies Influencing Sungkai (Peronema canescens Jack.) Population Dynamics in City Forest, West Wales, Universitas Indonesia Campus, Depok

Sungkai (Peronema canescens), commonly used as an ornamental plant for household demarcation due to its aesthetic appeal, also offers medicinal benefits, effectively utilized in treating diverse ailments encompassing diseases, infections, and inflammations. This study aims to investigate the population dynamics and growth parameters of sungkai in the City Forest, West Wales, Universitas Indonesia Depok, we are focusing on various environmental factors and management practices affecting their development. Measurements of light intensity, temperature, humidity, soil pH, moisture, and wind speed were conducted to assess their impact on sungkai growth. The acquired data undergoes analysis through established formulas, and the outcomes are depicted in diagrams and tables. Results revealed congruence in altitude and light intensity with ideal growth conditions, while discrepancies in air humidity, soil pH, and moisture posed potential limitations to sungkai plant development. Analysis of sungkai tree diameters showcased varied growth rates, possibly influenced by plant spacing and nutrient competition. Furthermore, proposed intensive care practices such as pruning, thinning, and pest management are suggested as vital strategies to optimize sungkai growth. Overall, addressing these environmental factors and employing suitable management practices could significantly contribute to sustaining and enhancing the sungkai population within the City Forest, West Wales, Universitas Indonesia Depok.

Genetic and phenotypic of Pseudomonas aeruginosa sensitive to meropenem antibiotics after exposure to meropenem.

Pseudomonas aeruginosa, drug-resistant, causes health infections. Resistance to the preferred therapy meropenem is a serious threat. This study aimed to analyze changes in meropenem minimum inhibitory concentration (MIC), changes in ampC, mexA, and oprD gene expression, and the correlation between MIC and ampC, mexA, and oprD gene expression after meropenem exposure. Ten isolates of P. aeruginosa from the Clinical Microbiology Department, Faculty of Medicine, Universitas Indonesia were used. After the bacteria were shown to be sensitive to meropenem phenotypically, intrinsic resistance genes were detected using PCR. After meropenem exposure on Days 5 and 12, sensitivity testing was carried out with the concentration gradient method and RNA was detected using real-time RT-PCR. All P. aeruginosa isolates that were phenotypically sensitive to meropenem had the ampC, mexA, and oprD genes. An increase in MIC, an increase in ampC and mexA gene expression, and a decrease in oprD gene expression were observed after meropenem exposure. There was a very strong and significant correlation (p ≤ 0.05) between MIC and oprD gene expression after Day 12 of meropenem exposure. Although there were no significant differences in MIC and ampC, mexA, and oprD gene expression between Day 5 and Day 12, there was a very strong and significant correlation between MIC and oprD gene expression on Day 12 (p ≤ 0.05). This indicates that decreasing oprD gene expression has the potential to increase meropenem resistance in Pseudomonas aeruginosa.

Lymph Node Metastasis in Papillary Thyroid Carcinoma, A Study of BRAF V600E and TERT Promoter Mutations.

This study was designed to determine the role of BRAF V600E and TERT mutations in the incidence of neck lymph node (LN) metastasis in patients with papillary thyroid carcinoma (PTC). This was a cross-sectional study, involving PTC patients at Dr. Cipto Mangunkusumo Hospital, Jakarta. Data were obtained retrospectively based on medical records, except for BRAF V600E and TERT promoter mutations. Tumor tissue specimens of PTC's patients were transferred to the Integrated Laboratory of Faculty of Medicine, Universitas Indonesia. BRAF gene multiplication was performed with KOD One PCR Master Mix (Toyobo KMM-201), while TERT gene multiplication was performed with PCR Master Mix. Data analysis was performed with SPSS version 20. The data were analyzed using univariate and bivariate analysis with the Chi-Square test. 42 PTC patients were included in the study; 19 (45%) had BRAF mutation, 20 (48%) had TERT mutation, and 20 (48%) had LN metastases. BRAF V600E mutation was associated with LN metastasis [p<0.001, OR = 25.33 (95% CI 4.92 - 130.34)], while TERT mutation was not. Patients with BRAF+ and TERT- mutations were 18.00 times (95% CI 2.01 - 161.05) more likely to develop LN metastasis than patients with BRAF- and TERT-. Furthermore, the presence of TERT mutation along with BRAF mutation increased the risk to 60.00 (95% CI 4.72 - 763.04) higher than patients with BRAF- and TERT-. BRAF mutation was associated with LN metastasis in PTC patients, but not TERT mutations. However, the presence of TERT mutation in PTC's patients with BRAF mutation increased the risk of LN metastasis.

Cover, Content, and Editorial Note from Borneo J Pharm Vol. 7 No. 2 May 2024

Assalamu’alaikum Wr. Wb. Alhamdulillahirabbil ‘alamin. The next edition of the Borneo Journal of Pharmacy (Borneo J Pharm), has been published in May 2024. This edition contains ten articles: Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Microbiology Pharmacy, Natural Product Development, Clinical-Community Pharmacy, and Management Pharmacy. This edition includes writings from five countries: Indonesia, Malaysia, Nigeria, Sierra Leone, and Uganda. The authors come from several institutions, including Institut Teknologi Bandung, Universitas Darussalam Gontor, Universitas Koperasi Indonesia, Universitas Lambung Mangkurat, Universitas Muhammadiyah Prof. DR. HAMKA, Institut Pertanian Bogor, Biomatics Indonesia, Indonesian Institute of Bioinformatics, Universitas Nasional, University of Ilorin, Summit University, Ambrose Alli University, Mbarara University of Science and Technology, Kampala International University, Premium Medical Services, Kebbi State University of Science and Technology, Clarke International University, Universitas Muhammadiyah Yogyakarta, International Islamic University Malaysia, Universitas Mahasaraswati Denpasar, Universitas Indonesia, Universitas 17 Agustus 1945 Jakarta, National Research and Innovation Agency of the Republic of Indonesia, Menur National Mental Hospital, and East Java Provincial Health Service. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors, could re-participate for publication in the next edition on August 2024. Wassalamu’alaikum Wr. Wb.

Incorporating Life Cycle Assessment in the Green Metric Ranking: a Conceptual Approach

Integrating sustainability principles into their daily operations is an overarching goal of universities and higher education institutions (HEIs), as knowledge multipliers, have to perform (Filimonau et al., 2021).Various studies have demonstrated that the operational activities of universities cause GWP emissions and, in general, negative environmental impacts, due mainly to student and staff mobility, on-campus energy and water consumption, and waste production (Jürgens et al., 2023). Findler et al. (2019) outlined numerous analytical methods, ranging from input-output analysis to full Life Cycle Assessment (LCA), for evaluating the carbon footprints of universities and colleges.Concurrently, a variety of tools have been devised to measure sustainability based on environmental metrics, such as the Green Metric (GM) ranking developed by Universitas Indonesia (UI). The GM, which is first in which tops university sustainability rankings (Marrone et al., 2018), rates HEIs by utilizing 51 criteria across 6 rating areas. Researchers analyzed the UI Green Metric World Ranking system to examine the requirements for a fair sustainability ranking of worldwide HEIs, although the latter were only examined in general without inspecting each item separately (Boiocchi et al., 2023).In order to lessen the environmental impacts of HEIs, recognized and robust methods must be used to identify appropriate and effective measures. LCA is a standardized (ISO 14040 and 14044) tool for quantifying and reducing environmental impacts throughout the entire life cycle of a product, service, or organization.This study is focused on understanding how LCA can be integrated into GM, and more specifically, how it can assist in achieving a consistent and structured review of specific indexes such as EC4, EC7, EC8, WR2, and TR1.The analysis was conducted by comparing the items one by one. Such a method was implemented as a results of the authors' specialized background, the scientific literature of interest, and the adoption of a critical thinking approach.The study results emphasize the necessity of incorporating LCA into the environmental sustainability strategies of HEIs. This integration is crucial for developing a robust approach adaptable to various local contexts, enhancing the precision in assessing and improving HEIs' sustainability practices. Such a strategy will align HEIs' operational activities more effectively with sustainable development goals. The application of the conceptual approach to a case study is recommended.