Unilateral Nasal Lesions Research Articles

Evaluation of narrow band imaging for diagnosis of unilateral nasal lesions.

This study aimed to investigate the effect of narrow band imaging (NBI) examination on differentiating diagnosis between benign and malignant neoplasms involving nasal cavity. A retrospective study was conducted to analyse cases from January 2018 to December 2019 at a single centre. A total of 188 consecutive patients who were newly diagnosed with lesions in unilateral nasal cavity underwent complete examination with white light endoscopy (WLE) and NBI endoscopy. Biopsy specimens were harvested from the target lesions and sent to the pathologist for definite diagnosis. Participants with a history of congenital malformation, trauma and surgery in nasal cavity were excluded from the study. Endoscopic diagnosis was assessed using sensitivity, specificity, accuracy, positive and negative predictive values (PPV and NPV, respectively). In identifying benign and malignant lesions of nasal cavity, NBI had a significant higher sensitivity (92.7% vs 70.7%, P=.020) and NPV (98% vs 92.3%, P=.032) than WLE, but there were no significant differences between NBI and WLE in specificity (98.6% vs 97.3%, P=.684), accuracy (97.3% vs 91.5%, P=.416) and PPV (95% vs 87.9%, P=.400). NBI as an emerging technique can improve the diagnostic accuracy by distinguishing benign and malignant lesions in nasal cavity and remains a promising and helpful adjunct to the endoscopy techniques.

Incidence of nasal inverted papilloma in unilateral nasal lesions in Damietta Governorate

Background Unilateral nasal lesions are a characteristics group that need special attention from ear, nose and throat surgeons. Inverted nasal papilloma is one of such lesions. However, its incidence and pattern are not well-defined in Egypt.Aim To estimate the incidence of inverted nasal papilloma among patients with unilateral nasal lesions.Patients and methods A prospective analysis of patients presented and treated owing to unilateral nasal lesion was conducted in a 2-year duration. Patient demographics, clinical presentation, and histopathological diagnoses were document.Results There were 117 (53 males and 64 female) patients with unilateral nasal lesions. The mean age was 44.14 (±10.80) years. Nasal obstruction was reported in 50.4%, nasal discharge in 17.1%, epistaxis in 12%, and facial pain in 5.1%. The lesion was inflammatory in 79.5% and neoplastic in 20.5%. The most common inflammatory lesion was chronic rhinosinusitis (44.4%), whereas the most common neoplastic lesion was inverted papilloma in 10.3%, and squamous cell carcinoma in 4.3%. However, males were significantly higher in neoplastic and inverted nasal papilloma. Nasal obstruction was increased in inflammatory lesions, whereas nasal discharge, facial pain, and epistaxis were increased in neoplastic group.Conclusion Inverted nasal papilloma was reported in 10.3%. It had male predilection and usually presented in the fifth decade, and nasal discharge, epistaxis, and facial pain were significantly associated with the disease.

Tumor carcinoide atípico nasal. Descripción de un caso

Introduction: Carcinoid tumors are neuroendocrine tumors that are usually located on the gastrointestinal system, but infrequent in the sinus area. Description: The case of a 55-year-old woman with a unilateral nasal mass is described. The pathological analysis shows histological and immunohistochemical characteristics compatible with atypical carcinoid tumor. Discussion: carcinoid tumors may be typical or atypical according to their degree of differentiation. Although rare, they should be considered in differential diagnosis of unilateral polyposis. Treatment is essentially surgical. Conclusions: This case highlights the importance of histopathological analysis of all unilateral nasal lesions.

Tek taraflı nazal patolojilerin klinik prezentasyonu ve yönetimi

Objective: To evaluate the histopathological examination results, frequency of lesions and associated symptoms in patients with established unilateral nasal pathology. Methods: Medical records of 73 patients with unilateral nasal lesions who undergone histopathological examination were analyzed retrospectively. Clinical presentation, examination and radiological findings, treatment and follow-up process of the patients were evaluated. Results: Neoplastic (n=16) and non-neoplastic (n=57) pathologies were detected in 73 patients. Non-neoplastic lesions consisted of inflammatory polyps (n=16), chronic sinusitis (n=11), anthrocoanal polyps (n=6) which were the most striking unilateral nasal pathologies. Neoplastic group (n=16) comprised of 2 malignant and 14 benign cases which were classified as adenocarcinoma (n=1), adenoid cystic carcinoma (n=1), inverted papilloma (n=8), hemangioendothelioma (n=1), capillary hemangioma (n=1), fibrous dysplasia (n=1), osteoma (n=1) and pyogenic granuloma (n=2). The most frequently observed symptom was unilateral nasal obstruction. Especially in cases with neoplasms, the frequency of epistaxis increased significantly (p

Incidence of neoplasia in patients with clinically suspicious nasal lesions and the value of computed tomography imaging in diagnosis.

There is no consensus as to whether all routine bilateral polypectomy specimens should be sent for formal histopathological diagnosis to exclude underlying neoplastic pathology. This study assessed the necessity for histopathological investigation as routine practice in cases of bilateral and unilateral nasal lesions by estimating the incidence of unexpected pathologies. It also evaluated the ability of computed tomography to predict histopathological diagnosis in patients with unilateral nasal lesions. A retrospective analysis was conducted of 98 patients undergoing nasal polypectomy over a 12-month period. Five of 23 patients with a unilateral lesion on nasendoscopy had inverted papillomas on histopathological examination. None of the 75 patients with clinically bilateral lesions on nasendoscopy showed evidence of neoplasia on histopathological examination. Patients with inverted papillomas had significantly lower total Lund-Mackay scores than those with bilateral polyps. Asymmetry scores of inverted papilloma patients were significantly higher compared to both bilateral and unilateral polyps patients. The results suggest that histopathological diagnosis is only necessary in unilateral lesion patients as no unexpected histopathological diagnoses were made in bilateral lesion patients. Computed tomography imaging may have a role in predicting histopathological diagnosis by demonstrating asymmetry and less overall sinus opacification in patients with neoplastic lesions.

Narrow-band imaging in the diagnosis of vascular nasal lesions

The management of unilateral nasal lesions can sometimes be a challenge and an ordinary bioptic assessment should be avoided in order to prevent complications due to their possible vascular or meningoencephalic origin. Narrow-band imaging (NBI) endoscopy could improve the diagnosis of vascular nasal formations by enhancing the visualisation of the mucosal microvascular supply. We describe the case of a 68-year-old male patient who was brought to our attention because of a left nasopharyngeal mass that had elsewhere been unsuccessfully biopsied (with conspicuous bleeding) and assessed by means of traditional endoscopic and radiological techniques. NBI endoscopy revealed increased vasculature covering most of the mucosal surface without any features suggestive for malignancy. Subsequent angiography showed that the feeding vessel was the left sphenopalatine artery, which was embolised using 150–250μm Contour embospheres. The mass was then completely removed surgically using an NBI-assisted endoscopic technique, and a histopathological examination revealed it was a hemangiopericytoma-like (HPCL) tumor. This case suggests the usefulness of NBI endoscopy in diagnosing unilateral vascularised nasal lesions and guiding the therapeutic approach before and during major surgery.