Unilateral Angioedema Research Articles

Alteplase-induced facial orolingual angioedema (P12-5.012)

<h3>Objective:</h3> Represent post-thrombolysis angioedema, a relatively common adverse effect seen after administration of alteplase for acute ischemic stroke. <h3>Background:</h3> r-TPA induced angioedema is a common clinical finding after medication infusion for acute stroke. The incidence of this complication ranges from 1.3–8% (3, 4). Prognosis is usually good; most patients have symptom resolution within 72 hours (5). <h3>Design/Methods:</h3> Literature review revealed how signs and symptoms of angioedema differ in presentation and severity. We gathered case reports from the last decade to identify the most common location of stroke, site of edema, treatment used and complications of angioedema. <h3>Results:</h3> Symptoms usually began within 150 minutes after initial infusion (mean 70 minutes) and usually presented with unilateral angioedema, contralaterally to the side of the stroke. Approximately 30% of the patients required mechanical ventilation; most were on treatment with ACE inhibitors. The authors usually treated patients with a combination of steroids, antihistamines, adrenalin, or Icatibant, with complete recovery within 24 to 48 hours. <h3>Conclusions:</h3> Patients treated with Icatibant improved within minutes and achieved full remission in the first three hours. We believe it may become the standard of care in patients presenting with this uncommon but potentially life-threatening complication. <b>Disclosure:</b> Dr. Ayala Alvarez has nothing to disclose. Dr. Roque Sanchez has nothing to disclose. Dr. Jimenez-Ruiz has nothing to disclose. Dr. GOMEZ FIGUEROA has nothing to disclose. Omar Cardenas-Sanchez has nothing to disclose. Dr. Ruiz-Sandoval has nothing to disclose.

Unilateral Angioedema of Tongue following Ginseng containing Multivitamin intake in patient with SLE: A case report.

Unilateral angioedema of tongue is a rare presentation of allergic reaction. If not identified and treated immediately, may lead to compromise of the airway and warrant tracheostomy or sometimes may also lead to death. In lupus patients, angioedema may be due to an acquired type of C1 inhibitor deficiency. Acquired angioedema can also be drug induced mostly seen with the use of non-steroidal anti-inflammatory drugs, contrast media, proton pump inhibitors and serotonin reuptake inhibitors. There are rare cases reported of angioedema related to Ginseng intake.

Ceftriaxone Induced Unilateral Facial Angioedema

We report a case receiving treatment with diclofenac sodium and ceftriaxone, who presented with facial unilateral angioedema attacks twice. Unilateral angioedema is a rare adverse reaction after NSAID usage. There is no previous report in the literature about ceftriaxone induced unilateral facial angioedema. To our knowledge this is the first reported case of unilateral facial angioedema following ceftriaxone treatment.

Unilateral tongue angioedema caused by angiotensin-converting enzyme inhibitor

We report a case of an elderly man receiving treatment with perindopril, who presented with angioedema of the left side of the tongue, floor of the mouth and upper neck. This affected his speech and swallowing, and occurred one day after a burr hole and evacuation procedure undertaken to treat a subdural haematoma. The patient was kept under close observation and treated with intravenous hydrocortisone. The angioedema resolved completely in two days. This is the third reported case of unilateral tongue angioedema occurring secondary to angiotensin-converting enzyme inhibitor use. Case report and literature review concerning angiotensin-converting enzyme inhibitor induced angioedema. Unilateral angioedema of the tongue is a rare adverse reaction to angiotensin-converting enzyme inhibitors. Early recognition may prevent unnecessary surgical intervention and complications.

Aspirin‐induced unilateral angioedema of the tongue

Aspirin‐induced unilateral angioedema of the tongue