Structural and tectonic control on karstic hydrogeology of the plateau Mahafaly (semiarid coastal area, South-West of Madagascar). The southwestern coast of Madagascar is characterized by a semiarid climate and low fresh water resources, which slow down the economic development. The studied area, located south of Toliara, is separated into a western coast of aeolian dunes and sandstones, where most of the people live, and the eastern, almost unoccupied, calcareous Mahafaly plateau. The coastal aquifer is dominated by salty water. The conductivity, close to 6000pS/cm in the north, decreases to 3000pS !cm in the south. The coastal plain is bordered to the East by highly karstified Cenozoic limestone, separated by a north-south cliff corresponding to the Toliara fault scarp. Surveys in coastal wells and in karstic aquifers clearly point out tidal influence on piezometric level and conductivity. In the north, the limestone cliff is directly in contact with the sea, whose water contaminates the karstic aquifer according to tidal variations. In the south, fresh water flows out on the beach by resurgences in the Quaternary sandstones, probably connected to the Eocene limestones, 5 km to the east. Drillings and exploration of some shafts on the plateau permitted access to the ground water table. It displays various conductivities ranging between 1500µS/cm and 5000µS/ cm, unusually high for a karstic aquifer far away from the coast. The mapping of such conductivities suggests more complex phenomena than only marine intrusions into the different aquifer systems. Chemical and isotopic analyses show an obvious seawater intrusion and evaporation influence for the coastal aquifer, lin the karstic aquifer, however, trace element analyses evoke contamination by upwelling of deep mineralized water. Salty water is frequent eastward on the basement and in the Mesozic formations. Today, fracture zones in both the coastal sandstones and in the Cenozoic limestone units control ground water circulations. Such fractures result from extensional phases in the past. The surface joint directions N-S, NE-SW and NW-SE . reflect the deep-seated horst and graben structures. Microtectonic analyses give evidence of a post-Eocene WNW-ESE extension, and recent seismic data define an E-W extensional regime. The underground flowpaths are mostly on fractures oriented along the present stress field. The tectonic history in the area and the chemical composition of the waters suggest a connection of the karst aquifer with circulations from deep formations through deep-seated faults belonging to the Toliara fault system. This could explain abnormal salinities in the karstic system, far away from the coast.